Lysophosphatidylcholine increases the neurotoxicity of Alzheimer's amyloid β1-42 peptide: Role of oligomer formation

Neuroscience

Volumn 292, Issue , 2015, Pages 159-169

  Sheikh, A Md ^a   Michikawa, M ^b   Kim, S U ^c,d   Nagai, A ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d Chung Ang University College of Medicine   (South Korea)

Author keywords

Alzheimer's disease; Amyloid ; Lysophosphatidylcholine; Neuronal apoptosis; Oligomer

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CASPASE; CASPASE 9; LACTATE DEHYDROGENASE; LYSOPHOSPHATIDYLCHOLINE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TETRAZOLIUM; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); BAX PROTEIN, HUMAN; BCL2 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; DOT HYBRIDIZATION; ENZYME RELEASE; HUMAN; HUMAN CELL; IMMUNOASSAY; IMMUNOPRECIPITATION; MICELLE; NERVE DEGENERATION; NEUROTOXICITY; NICK END LABELING; OLIGOMERIZATION; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUPERNATANT; WESTERN BLOTTING; CELL SURVIVAL; IMMUNOBLOTTING; METABOLISM; NERVE CELL; PHYSIOLOGY; TUMOR CELL LINE; TUNEL ASSAY;

AMYLOID BETA-PEPTIDES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; LYSOPHOSPHATIDYLCHOLINES; NEURONS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES;

EID: 84925004232     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.02.034     Document Type: Article

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