ROS-triggered signaling pathways involved in the cytotoxicity and tumor promotion effects of pentachlorophenol and tetrachlorohydroquinone

Chemical Research in Toxicology

Volumn 28, Issue 3, 2015, Pages 339-350

  Chen, Hsiu Min ^a   Lee, Yu Hsuan ^a   Wang, Ying Jan ^a,b,c  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b ASIA UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROLIPOATE; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; PENTACHLOROPHENOL; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TETRACHLOROHYDROQUINONE; TUMOR PROMOTER; 2,3,5,6-TETRACHLOROHYDROQUINONE; CARCINOGEN; HYDROQUINONE DERIVATIVE; POLLUTANT;

APOPTOSIS; CARCINOGENESIS; CELL DEATH; CELL TRANSFORMATION; CYTOTOXICITY; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; FIBROBLAST; GENE OVEREXPRESSION; GENOTOXICITY; HUMAN; IN VITRO STUDY; LIPID PEROXIDATION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN DEPLETION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SPLEEN CELL; TUMOR MODEL; TUMOR PROMOTION; ANIMAL; DRUG EFFECTS; METABOLISM; POLLUTANT; TOXICITY;

MAMMALIA;

ANIMALS; CARCINOGENS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; HUMANS; HYDROQUINONES; OXIDATIVE STRESS; PENTACHLOROPHENOL; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84924865675     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx500487w     Document Type: Review

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