Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol

Chemico-Biological Interactions

Volumn 105, Issue 1, 1997, Pages 1-16

  Wang, Ying Jan ^a   Ho, Yuan Soon ^b   Chu, Shen Way ^a   Lien, Heng Jung ^a   Liu, Ting Hsiu ^a   Lin, Jen Kun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Glutathione depletion; p53 protein; Tetrachlorohydroquinone; Transformation

Indexed keywords

DNA FRAGMENT; GLUTATHIONE; PROTEIN P53; TETRACHLOROHYDROQUINONE;

ANIMAL CELL; ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; EMBRYO; FIBROBLAST; GENOTOXICITY; LIVER; METABOLITE; MOUSE; NONHUMAN;

3T3 CELLS; ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMES; DNA FRAGMENTATION; ELECTROPHORESIS, CAPILLARY; GLUTATHIONE; HYDROQUINONES; MICE; MICE, INBRED C3H; PENTACHLOROPHENOL; PESTICIDES; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0030849329     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(97)00023-9     Document Type: Article

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