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Volumn 98, Issue , 2015, Pages 1-8

Arginase inhibition enhances angiogenesis in endothelial cells exposed to hypoxia

Author keywords

Angiogenesis; Arginase; Endothelial cell; Endothelial nitric oxide synthase (eNOS); Reactive oxygen species (ROS)

Indexed keywords

ARGINASE; ARGINASE 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SERINE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A;

EID: 84924856530     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2014.11.002     Document Type: Article
Times cited : (23)

References (45)
  • 2
    • 84857535891 scopus 로고    scopus 로고
    • Critical role of hypoxia sensor-HIF-1alpha in VEGF gene activation. Implications for angiogenesis and tissue injury healing
    • Ahluwalia A., Tarnawski A.S. Critical role of hypoxia sensor-HIF-1alpha in VEGF gene activation. Implications for angiogenesis and tissue injury healing. Curr. Med. Chem. 2012, 19:90-97.
    • (2012) Curr. Med. Chem. , vol.19 , pp. 90-97
    • Ahluwalia, A.1    Tarnawski, A.S.2
  • 6
    • 67349119514 scopus 로고    scopus 로고
    • Regulation of angiogenesis by oxygen sensing mechanisms
    • Fong G.H. Regulation of angiogenesis by oxygen sensing mechanisms. J. Mol. Med. (Berl) 2009, 87:549-560.
    • (2009) J. Mol. Med. (Berl) , vol.87 , pp. 549-560
    • Fong, G.H.1
  • 7
    • 33645780634 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase in vascular disease: from marvel to menace
    • Forstermann U., Munzel T. Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation 2006, 113:1708-1714.
    • (2006) Circulation , vol.113 , pp. 1708-1714
    • Forstermann, U.1    Munzel, T.2
  • 8
    • 84877102554 scopus 로고    scopus 로고
    • Crosstalk between oxygen- and nitric oxide-dependent signaling pathways in angiogenesis
    • Fraisl P. Crosstalk between oxygen- and nitric oxide-dependent signaling pathways in angiogenesis. Exp. Cell Res. 2013, 319:1331-1339.
    • (2013) Exp. Cell Res. , vol.319 , pp. 1331-1339
    • Fraisl, P.1
  • 10
    • 84866940088 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factor 1 in atherosclerosis
    • Gao L., Chen Q., Zhou X., Fan L. The role of hypoxia-inducible factor 1 in atherosclerosis. J. Clin. Pathol. 2012, 65:872-876.
    • (2012) J. Clin. Pathol. , vol.65 , pp. 872-876
    • Gao, L.1    Chen, Q.2    Zhou, X.3    Fan, L.4
  • 11
    • 84864490199 scopus 로고    scopus 로고
    • Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production
    • Gonon A.T., Jung C., Katz A., Westerblad H., Shemyakin A., Sjoquist P.O., Lundberg J.O., Pernow J. Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production. PLoS One 2012, 7:e42038.
    • (2012) PLoS One , vol.7 , pp. e42038
    • Gonon, A.T.1    Jung, C.2    Katz, A.3    Westerblad, H.4    Shemyakin, A.5    Sjoquist, P.O.6    Lundberg, J.O.7    Pernow, J.8
  • 13
    • 0035000258 scopus 로고    scopus 로고
    • Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell metabolism
    • Hoffmann A., Gloe T., Pohl U. Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell metabolism. J. Cell. Physiol. 2001, 188:33-44.
    • (2001) J. Cell. Physiol. , vol.188 , pp. 33-44
    • Hoffmann, A.1    Gloe, T.2    Pohl, U.3
  • 15
    • 2142649185 scopus 로고    scopus 로고
    • Dual actions of nitric oxide on angiogenesis: possible roles of PKC, ERK, and AP-1
    • Jones M.K., Tsugawa K., Tarnawski A.S., Baatar D. Dual actions of nitric oxide on angiogenesis: possible roles of PKC, ERK, and AP-1. Biochem. Biophys. Res. Commun. 2004, 318:520-528.
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 520-528
    • Jones, M.K.1    Tsugawa, K.2    Tarnawski, A.S.3    Baatar, D.4
  • 16
    • 72049107764 scopus 로고    scopus 로고
    • Arginase inhibition mediates cardioprotection during ischaemia-reperfusion
    • Jung C., Gonon A.T., Sjoquist P.O., Lundberg J.O., Pernow J. Arginase inhibition mediates cardioprotection during ischaemia-reperfusion. Cardiovasc. Res. 2010, 85:147-154.
    • (2010) Cardiovasc. Res. , vol.85 , pp. 147-154
    • Jung, C.1    Gonon, A.T.2    Sjoquist, P.O.3    Lundberg, J.O.4    Pernow, J.5
  • 19
    • 0042889191 scopus 로고    scopus 로고
    • Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis
    • Kimura H., Esumi H. Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis. Acta Biochim. Pol. 2003, 50:49-59.
    • (2003) Acta Biochim. Pol. , vol.50 , pp. 49-59
    • Kimura, H.1    Esumi, H.2
  • 20
    • 0033975850 scopus 로고    scopus 로고
    • Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide
    • Kimura H., Weisz A., Kurashima Y., Hashimoto K., Ogura T., D'Acquisto F., Addeo R., Makuuchi M., Esumi H. Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide. Blood 2000, 95:189-197.
    • (2000) Blood , vol.95 , pp. 189-197
    • Kimura, H.1    Weisz, A.2    Kurashima, Y.3    Hashimoto, K.4    Ogura, T.5    D'Acquisto, F.6    Addeo, R.7    Makuuchi, M.8    Esumi, H.9
  • 21
    • 0035910429 scopus 로고    scopus 로고
    • Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide
    • Kimura H., Weisz A., Ogura T., Hitomi Y., Kurashima Y., Hashimoto K., D'Acquisto F., Makuuchi M., Esumi H. Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide. J. Biol. Chem. 2001, 276:2292-2298.
    • (2001) J. Biol. Chem. , vol.276 , pp. 2292-2298
    • Kimura, H.1    Weisz, A.2    Ogura, T.3    Hitomi, Y.4    Kurashima, Y.5    Hashimoto, K.6    D'Acquisto, F.7    Makuuchi, M.8    Esumi, H.9
  • 22
    • 84859157095 scopus 로고    scopus 로고
    • Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins
    • Krause B.J., Prieto C.P., Munoz-Urrutia E., San Martin S., Sobrevia L., Casanello P. Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins. Placenta 2012, 33:360-366.
    • (2012) Placenta , vol.33 , pp. 360-366
    • Krause, B.J.1    Prieto, C.P.2    Munoz-Urrutia, E.3    San Martin, S.4    Sobrevia, L.5    Casanello, P.6
  • 24
    • 0036150703 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1/vascular endothelial growth factor pathway for adventitial vasa vasorum formation in hypertensive rat aorta
    • Kuwahara F., Kai H., Tokuda K., Shibata R., Kusaba K., Tahara N., Niiyama H., Nagata T., Imaizumi T. Hypoxia-inducible factor-1/vascular endothelial growth factor pathway for adventitial vasa vasorum formation in hypertensive rat aorta. Hypertension 2002, 39:46-50.
    • (2002) Hypertension , vol.39 , pp. 46-50
    • Kuwahara, F.1    Kai, H.2    Tokuda, K.3    Shibata, R.4    Kusaba, K.5    Tahara, N.6    Niiyama, H.7    Nagata, T.8    Imaizumi, T.9
  • 25
    • 84883725551 scopus 로고    scopus 로고
    • Therapeutic potential of the nitrite-generated NO pathway in vascular dysfunction
    • Madigan M., Zuckerbraun B. Therapeutic potential of the nitrite-generated NO pathway in vascular dysfunction. Front. Immunol. 2013, 4:174.
    • (2013) Front. Immunol. , vol.4 , pp. 174
    • Madigan, M.1    Zuckerbraun, B.2
  • 27
    • 0036402941 scopus 로고    scopus 로고
    • Regulation of enzymes of the urea cycle and arginine metabolism
    • Morris S.M. Regulation of enzymes of the urea cycle and arginine metabolism. Annu. Rev. Nutr. 2002, 22:87-105.
    • (2002) Annu. Rev. Nutr. , vol.22 , pp. 87-105
    • Morris, S.M.1
  • 28
    • 70350303578 scopus 로고    scopus 로고
    • Recent advances in arginine metabolism: roles and regulation of the arginases
    • Morris S.M. Recent advances in arginine metabolism: roles and regulation of the arginases. Br. J. Pharmacol. 2009, 157:922-930.
    • (2009) Br. J. Pharmacol. , vol.157 , pp. 922-930
    • Morris, S.M.1
  • 29
    • 59249083671 scopus 로고    scopus 로고
    • Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders
    • Morris C.R., Gladwin M.T., Kato G.J. Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders. Curr. Mol. Med. 2008, 8:620-632.
    • (2008) Curr. Mol. Med. , vol.8 , pp. 620-632
    • Morris, C.R.1    Gladwin, M.T.2    Kato, G.J.3
  • 30
    • 84859161881 scopus 로고    scopus 로고
    • Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium
    • Prieto C.P., Krause B.J., Quezada C., San Martin R., Sobrevia L., Casanello P. Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium. Placenta 2011, 32:932-940.
    • (2011) Placenta , vol.32 , pp. 932-940
    • Prieto, C.P.1    Krause, B.J.2    Quezada, C.3    San Martin, R.4    Sobrevia, L.5    Casanello, P.6
  • 33
    • 33750491292 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling
    • Ryoo S., Lemmon C.A., Soucy K.G., Gupta G., White A.R., Nyhan D., Shoukas A., Romer L.H., Berkowitz D.E. Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling. Circ. Res. 2006, 99:951-960.
    • (2006) Circ. Res. , vol.99 , pp. 951-960
    • Ryoo, S.1    Lemmon, C.A.2    Soucy, K.G.3    Gupta, G.4    White, A.R.5    Nyhan, D.6    Shoukas, A.7    Romer, L.H.8    Berkowitz, D.E.9
  • 34
    • 72049086478 scopus 로고    scopus 로고
    • Arginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia
    • Sankaralingam S., Xu H., Davidge S.T. Arginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia. Cardiovasc. Res. 2010, 85:194-203.
    • (2010) Cardiovasc. Res. , vol.85 , pp. 194-203
    • Sankaralingam, S.1    Xu, H.2    Davidge, S.T.3
  • 35
    • 34447579911 scopus 로고    scopus 로고
    • Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats
    • Sasaki A., Doi S., Mizutani S., Azuma H. Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 292:L1480-L1487.
    • (2007) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.292 , pp. L1480-L1487
    • Sasaki, A.1    Doi, S.2    Mizutani, S.3    Azuma, H.4
  • 37
    • 84896983593 scopus 로고    scopus 로고
    • Hypobaric hypoxia induced arginase expression limits nitric oxide availability and signaling in rodent heart
    • Singh M., Padhy G., Vats P., Bhargava K., Sethy N.K. Hypobaric hypoxia induced arginase expression limits nitric oxide availability and signaling in rodent heart. Biochim. Biophys. Acta 2014, 1840:1817-1824.
    • (2014) Biochim. Biophys. Acta , vol.1840 , pp. 1817-1824
    • Singh, M.1    Padhy, G.2    Vats, P.3    Bhargava, K.4    Sethy, N.K.5
  • 38
    • 84885963273 scopus 로고    scopus 로고
    • Development of novel arginase inhibitors for therapy of endothelial dysfunction
    • Steppan J., Nyhan D., Berkowitz D.E. Development of novel arginase inhibitors for therapy of endothelial dysfunction. Front. Immunol. 2013, 4:278.
    • (2013) Front. Immunol. , vol.4 , pp. 278
    • Steppan, J.1    Nyhan, D.2    Berkowitz, D.E.3
  • 39
    • 0036645303 scopus 로고    scopus 로고
    • Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
    • Takemoto M., Sun J., Hiroki J., Shimokawa H., Liao J.K. Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation 2002, 106:57-62.
    • (2002) Circulation , vol.106 , pp. 57-62
    • Takemoto, M.1    Sun, J.2    Hiroki, J.3    Shimokawa, H.4    Liao, J.K.5
  • 40
    • 79955008189 scopus 로고    scopus 로고
    • Angiogenic signaling aberrantly induced by tumor hypoxia
    • Takenaga K. Angiogenic signaling aberrantly induced by tumor hypoxia. Front. Biosci. (Landmark Ed.) 2011, 16:31-48.
    • (2011) Front. Biosci. (Landmark Ed.) , vol.16 , pp. 31-48
    • Takenaga, K.1
  • 41
    • 33747429424 scopus 로고    scopus 로고
    • Upregulation of arginase by H2O2 impairs endothelium-dependent nitric oxide-mediated dilation of coronary arterioles
    • Thengchaisri N., Hein T.W., Wang W., Xu X., Li Z., Fossum T.W., Kuo L. Upregulation of arginase by H2O2 impairs endothelium-dependent nitric oxide-mediated dilation of coronary arterioles. Arterioscler. Thromb. Vasc. Biol. 2006, 26:2035-2042.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 2035-2042
    • Thengchaisri, N.1    Hein, T.W.2    Wang, W.3    Xu, X.4    Li, Z.5    Fossum, T.W.6    Kuo, L.7
  • 42
    • 84870278725 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization and cell death during myocardial infarction: roles of calcium and reactive oxygen species
    • Webster K.A. Mitochondrial membrane permeabilization and cell death during myocardial infarction: roles of calcium and reactive oxygen species. Futur. Cardiol. 2012, 8:863-884.
    • (2012) Futur. Cardiol. , vol.8 , pp. 863-884
    • Webster, K.A.1
  • 44
    • 33646038243 scopus 로고    scopus 로고
    • Endothelial arginase: a new target in atherosclerosis
    • Yang Z., Ming X.F. Endothelial arginase: a new target in atherosclerosis. Curr. Hypertens. Rep. 2006, 8:54-59.
    • (2006) Curr. Hypertens. Rep. , vol.8 , pp. 54-59
    • Yang, Z.1    Ming, X.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.