Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway

Cancer Letters

Volumn 360, Issue 2, 2015, Pages 125-133

  Zhao, Xiao Ping ^a   Wang, Meng ^a   Song, Yong ^a   Song, Kai ^a   Yan, Ting lin ^a   Wang, Lin ^a   Liu, Ke ^a   Shang, Zheng jun ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Adhesion; Fibroblasts; Melanoma; Microvesicles; VCAM 1; VLA 4

Indexed keywords

EPIDERMAL GROWTH FACTOR; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL ADHESION; CELL COMMUNICATION; CELL HYPOXIA; CELL INTERACTION; CELL TRANSFORMATION; CELL VACUOLE; CONTROLLED STUDY; FIBROBLAST; MELANOMA; MELANOMA CELL; MICROVESICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; SIGNAL TRANSDUCTION; UPREGULATION; 3T3 CELL LINE; ANIMAL; CELL MEMBRANE; CYTOPLASM VESICLE; ENZYMOLOGY; EXPERIMENTAL MELANOMA; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CELL COMMUNICATION; CELL MEMBRANE; CYTOPLASMIC VESICLES; FIBROBLASTS; INTEGRIN ALPHA4BETA1; MAP KINASE SIGNALING SYSTEM; MELANOMA, EXPERIMENTAL; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NIH 3T3 CELLS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84924855001     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.01.032     Document Type: Article

References (36)

1. Skog J., Wurdinger T., van Rijn S., Meijer D.H., Gainche L., Sena-Esteves M., et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol 2008, 10:1470-1476.
2. Al-Nedawi K., Meehan B., Kerbel R.S., Allison A.C., Rak J. Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:3794-3799.
3. Valenti R., Huber V., Iero M., Filipazzi P., Parmiani G., Rivoltini L. Tumor-released microvesicles as vehicles of immunosuppression. Cancer Res 2007, 67:2912-2915.
4. Lawrenson K., Grun B., Benjamin E., Jacobs I.J., Dafou D., Gayther S.A. Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer. Neoplasia 2010, 12:317-325.
5. Pavlides S., Whitaker-Menezes D., Castello-Cros R., Flomenberg N., Witkiewicz A.K., Frank P.G., et al. The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma. Cell Cycle 2009, 8:3984-4001.
6. Kaplan R.N., Riba R.D., Zacharoulis S., Bramley A.H., Vincent L., Costa C., et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005, 438:820-827.
7. Lu X., Mu E., Wei Y., Riethdorf S., Yang Q., Yuan M., et al. VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging alpha4beta1-positive osteoclast progenitors. Cancer Cell 2011, 20:701-714.
8. Slack-Davis J.K., Atkins K.A., Harrer C., Hershey E.D., Conaway M. Vascular cell adhesion molecule-1 is a regulator of ovarian cancer peritoneal metastasis. Cancer Res 2009, 69:1469-1476.
9. Valcarcel M., Carrascal T., Crende O., Vidal-Vanaclocha F. IL-18 regulates melanoma VLA-4 integrin activation through a hierarchized sequence of inflammatory factors. J. Invest. Dermatol 2013, 134(2):470-480.
10. Hind E., Heugh S., Ansa-Addo E.A., Antwi-Baffour S., Lange S., Inal J. Red cell PMVs, plasma membrane-derived vesicles calling out for standards. Biochem. Biophys. Res. Commun 2010, 399:465-469.
11. Castellana D., Zobairi F., Martinez M.C., Panaro M.A., Mitolo V., Freyssinet J.M., et al. Membrane microvesicles as actors in the establishment of a favorable prostatic tumoral niche: a role for activated fibroblasts and CX3CL1-CX3CR1 axis. Cancer Res 2009, 69:785-793.
12. Chen G., Zhu J.Y., Zhang Z.L., Zhang W., Ren J.G., Wu M., et al. Transformation of cell-derived microparticles into quantum-dot-labeled nanovectors for antitumor siRNA delivery. Angewandte Chemie 2014, 54(3):1036-1040.
13. Peinado H., Aleckovic M., Lavotshkin S., Matei I., Costa-Silva B., Moreno-Bueno G., et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat. Med 2012, 18:883-891.
14. Condeelis J., Pollard J.W. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006, 124:263-266.
15. Branco-Price C., Zhang N., Schnelle M., Evans C., Katschinski D.M., Liao D., et al. Endothelial cell HIF-1alpha and HIF-2alpha differentially regulate metastatic success. Cancer Cell 2012, 21:52-65.
16. Al-Nedawi K., Meehan B., Micallef J., Lhotak V., May L., Guha A., et al. Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat. Cell Biol 2008, 10:619-624.
17. van Niel G., Porto-Carreiro I., Simoes S., Raposo G. Exosomes: a common pathway for a specialized function. J. Biochem 2006, 140:13-21.
18. Grant R., Ansa-Addo E., Stratton D., Antwi-Baffour S., Jorfi S., Kholia S., et al. A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma. J. Immunol. Methods 2011, 371:143-151.
19. Klemke M., Weschenfelder T., Konstandin M.H., Samstag Y. High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers. J. Cell. Physiol 2007, 212:368-374.
20. Wysoczynski M., Ratajczak M.Z. Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors. Int. J. Cancer 2009, 125:1595-1603.
21. Tartour E., Dorval T., Mosseri V., Deneux L., Mathiot C., Brailly H., et al. Serum interleukin 6 and C-reactive protein levels correlate with resistance to IL-2 therapy and poor survival in melanoma patients. Br. J. Cancer 1994, 69:911-913.
22. Allinen M., Beroukhim R., Cai L., Brennan C., Lahti-Domenici J., Huang H., et al. Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell 2004, 6:17-32.
23. Okamoto I., Roka F., Krogler J., Endler G., Kaufmann S., Tockner S., et al. The EGF A61G polymorphism is associated with disease-free period and survival in malignant melanoma. J. Invest. Dermatol 2006, 126:2242-2246.
24. Cameron M.D., Schmidt E.E., Kerkvliet N., Nadkarni K.V., Morris V.L., Groom A.C., et al. Temporal progression of metastasis in lung: cell survival, dormancy, and location dependence of metastatic inefficiency. Cancer Res 2000, 60:2541-2546.
25. Luzzi K.J., MacDonald I.C., Schmidt E.E., Kerkvliet N., Morris V.L., Chambers A.F., et al. Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. Am. J. Pathol 1998, 153:865-873.
26. Dhomen N., Marais R. BRAF signaling and targeted therapies in melanoma. Hematol. Oncol. Clin. North Am 2009, 23:529-545. ix.
27. Hess A.R., Postovit L.M., Margaryan N.V., Seftor E.A., Schneider G.B., Seftor R.E., et al. Focal adhesion kinase promotes the aggressive melanoma phenotype. Cancer Res 2005, 65:9851-9860.
28. Ho J., de Moura M.B., Lin Y., Vincent G., Thorne S., Duncan L.M., et al. Importance of glycolysis and oxidative phosphorylation in advanced melanoma. Mol. Cancer 2012, 11:76.
29. Jiang C.C., Chen L.H., Gillespie S., Wang Y.F., Kiejda K.A., Zhang X.D., et al. Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis. Cancer Res 2007, 67:9750-9761.
30. Knutson J.R., Iida J., Fields G.B., McCarthy J.B. CD44/chondroitin sulfate proteoglycan and alpha 2 beta 1 integrin mediate human melanoma cell migration on type IV collagen and invasion of basement membranes. Mol. Biol. Cell 1996, 7:383-396.
31. Meier F., Busch S., Lasithiotakis K., Kulms D., Garbe C., Maczey E., et al. Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment. Br. J. Dermatol 2007, 156:1204-1213.
32. Stahl J.M., Sharma A., Cheung M., Zimmerman M., Cheng J.Q., Bosenberg M.W., et al. Deregulated Akt3 activity promotes development of malignant melanoma. Cancer Res 2004, 64:7002-7010.
33. Grange C., Tapparo M., Collino F., Vitillo L., Damasco C., Deregibus M.C., et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res 2011, 71:5346-5356.
34. Hood J.L., San R.S., Wickline S.A. Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis. Cancer Res 2011, 71:3792-3801.
35. Jung T., Castellana D., Klingbeil P., Cuesta Hernandez I., Vitacolonna M., Orlicky D.J., et al. CD44v6 dependence of premetastatic niche preparation by exosomes. Neoplasia 2009, 11:1093-1105.
36. Yu X., Harris S.L., Levine A.J. The regulation of exosome secretion: a novel function of the p53 protein. Cancer Res 2006, 66:4795-4801.