IL-18 regulates melanoma VLA-4 integrin activation through a hierarchized sequence of inflammatory factors

Journal of Investigative Dermatology

Volumn 134, Issue 2, 2014, Pages 470-480

  Valcárcel, María ^a   Carrascal, Teresa ^b   Crende, Olatz ^b   Vidal Vanaclocha, Fernando ^c  

^a Innoprot SL   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^c UNIVERSIDAD SAN PABLO CEU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; HYDROGEN PEROXIDE; INTERLEUKIN 18; INTERLEUKIN 1BETA; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VERY LATE ACTIVATION ANTIGEN 4;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL SUBPOPULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MELANOMA B16; MELANOMA CELL; METASTASIS POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; TUMOR MICROENVIRONMENT; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; CELL ADHESION; CELL LINE, TUMOR; HUMANS; INFLAMMATION; INTEGRIN ALPHA4BETA1; INTERLEUKIN-18; LIVER; LIVER NEOPLASMS; MALE; MELANOMA; MICE; MICE, INBRED C57BL; MICE, NUDE; PRIMARY CELL CULTURE; RECEPTORS, INTERLEUKIN-18; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RISK FACTORS; SKIN NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84892825349     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.342     Document Type: Article

References (38)

1. Anasagasti MJ, Alvarez A, Martin JJ et al. (1997) Sinusoidal endothelium release of hydrogen peroxide enhances very late antigen-4-mediated melanoma cell adherence and tumor cytotoxicity during interleukin-1 promotion of hepatic melanoma metastasis in mice. Hepatology 25: 840-6
2. Anasagasti MJ, Olaso E, Calvo F et al. (1997) Interleukin 1-dependent and -independent mouse melanoma metastases. J Natl Cancer Inst 89: 645-51
3. Barazi HO, Li Z, Cashel JA et al. (2002) Regulation of integrin function by CD47 ligands. Differential effects on alpha vbeta 3 and alpha 4beta1 integrin-mediated adhesion. J Biol Chem 277:42859-66
4. Canetti CA, Leung BP, Culshaw S et al. (2003) IL-18 enhances collageninduced arthritis by recruiting neutrophils via TNF-Alpha and leukotriene B4. J Immunol 171:1009-15
5. Chigaev A, Blenc AM, Braaten JV et al. (2001) Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. J Biol Chem 276:48670-8
6. Crende O, Sabatino M, Valcárcel M et al. (2013) Metastatic lesions with interleukin-18 dependent and independent genes in advanced stage melanoma patients. Am J Pathol 183:69-82
7. Hue J, Kim A, Song H et al. (2005) IL-18 enhances SCF production of melanoma cells by regulating ROI and p38 MAPK activity. Immunol Lett 96:211-7
8. Jouanneau J, Moens G, Bourgeois Y et al. (1994) A minority of carcinoma cells producing acidic fibroblast growth factor induces a community effect for tumor progression. Proc Natl Acad Sci USA 91:286-90
9. Jung MK, Song HK, Kim KE et al. (2006) IL-18 enhances the migration ability of murine melanoma cells through the generation of ROI and the MAPK pathway. Immunol Lett 107:125-30
10. Kim J, Kim C, Kim TS et al. (2006) IL-18 enhances thrombospondin-1 production in human gastric cancer via JNK pathway. Biochem Biophys Res Commun 344:1284-9
11. Kirsner RS, Eaglstein WH (1993) The wound healing process. Dermatol Clin Rev 11:629-40
12. Lissoni P, Brivio F, Rovelli F et al. (2000) Serum concentrations of interleukin-18 in early and advanced cancer patients: Enhanced secretion in metastatic disease. J Biol Regul Homeost Agents 14:275
13. Liu SY, Tsai MY, Chuang KP et al. (2008) Ligand binding of leukocyte integrin very late antigen-4 involves exposure of sulfhydryl groups and is subject to redox modulation. Eur J Immunol 38:410-23
14. Luque A, Gómez M, Puzon W et al. (1996) Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain. J Biol Chem 271:11067-75
15. Ly LV, Bronkhorst IH, van Beelen E et al. (2010) Inflammatory cytokines in eyes with uveal melanoma and relation with macrophage infiltration. Invest Ophthalmol Vis Sci 51:5445-51
16. Ma'rquez J, Kohli M, Arteta B et al. (2013) Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation. Int J Cancer. doi:10.1002/ijc.28232
17. Martìn-Padura I, Mortarini R, Lauri D et al. (1991) Heterogeneity in human melanoma cell adhesion to cytokine activated endothelial cells correlates with VLA-4 expression. Cancer Res 51:2239-41
18. Mattei S, Colombo MP, Melani C et al. (1994) Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int J Cancer 56:853-7
19. Mendoza L, Valcárcel M, Carrascal T et al. (2004) Inhibition of cytokineinduced microvascular arrest of tumor cells by recombinant endostatin prevents experimental hepatic melanoma metastasis. Cancer Res 64: 304-10
20. Moretti S, Pinzi C, Spallanzani A et al. (1999) Immunohistochemical evidence of cytokine networks during progression of human melanocytic lesions. Int J Cancer 84:160-8
21. Nakai N, Hartmann G, Kishimoto S et al. (2010) Dendritic cell vaccination in human melanoma: Relationships between clinical effects and vaccine parameters. Pigment Cell Melanoma Res Rev 23:607-19
22. Olaso E, Salado C, Egilegor E et al. (2003) Proangiogenic role of tumoractivated hepatic stellate cells in experimental melanoma metastasis. Hepatology 37:304-10
23. Park S, Yoon SY, Kim KE et al. (2009) Interleukin-18 induces transferrin expression in breast cancer cell line MCF-7. Cancer Lett 286: 189-95
24. Puren AJ, Fantuzzi G, Gu Y et al. (1998) Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFaproduction from non-CD14+ human blood mononuclear cells. J Clin Invest 101:711-21
25. Richmond A, Yang J, Su Y (2009) The good and the bad of chemokines/chemokine receptors in melanoma. Pigment Cell Melanoma Res Rev 22:175-86
26. Ruth JH, Park CC, Amin MA et al. (2010) Interleukin-18 as an in vivo mediator of monocyte recruitment in rodent models of rheumatoid arthritis. Arthritis Res Ther 12:R118
27. Saini A, Seller Z, Davies D et al. (1997) Activation status and function of the VLA-4 (alpha4beta1) integrin expressed on human melanoma cell lines. Int J Cancer 73:264-70
28. Schlesinger M, Naggi A, Torri G et al. (2010) Blocking of integrin-mediated human MV3 melanoma cell binding by commercial and modified heparins. Int J Clin Pharmacol Ther 48:448-50
29. Tarhini AA, Millward M, Mainwaring P et al. (2009) A phase 2, randomized study of SB-485232, rhIL-18, in patients with previously untreated metastatic melanoma. Cancer 115:859-68
30. Valca'rcel M, Mendoza L, Herna'ndez JJ et al. (2011) Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2. J Transl Med 9:142
31. Vidal-Vanaclocha F (2008) The prometastatic microenvironment of the liver. Cancer Microenviron 1:13-29
32. Vidal-Vanaclocha F (2011) The liver prometastatic reaction of cancer patients: Implications for microenvironment-dependent colon cancer gene regulation. Cancer Microenviron 4:163-80
33. Vidal-Vanaclocha F, Amézaga C, Asumendi A et al. (1994) Interleukin-1 receptor blockade reduces the number and size of murine B16 melanoma hepatic metastases. Cancer Res 54:2667-72
34. Vidal-Vanaclocha F, Fantuzzi G, Mendoza L et al. (2000) IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci USA 97:734-9
35. Vidal-Vanaclocha F, Mendoza L, Telleria N et al. (2006) Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression. Cancer Metastasis Rev 25:417-34
36. Yurkovetsky ZR, Kirkwood JM, Edington HD et al. (2010) Multiplex analysis of serum cytokines in melanoma patients treated with interferon-Alpha2b. Invest Ophthalmol Vis Sci 51:5445-51
37. Zimmer L, Livingstone E, Hillen U et al. (2012) Panniculitis with arthralgia in patients with melanoma treated with selective BRAF inhibitors and its management. Arch Dermatol 48:357-61
38. Zubia A, Mendoza L, Vivanco S et al. (2005) Application of stereocontrolled stepwise [3+2] cycloadditions to the preparation of inhibitors of alpha4beta1-integrin-mediated hepatic melanoma metastasis. Angew Chem Int Ed Engl 44:2903-7