Angiotensin-converting enzyme inhibition attenuates lipopolysaccharide-induced lung injury by regulating the balance between angiotensin-converting enzyme and angiotensin-converting enzyme 2 and inhibiting mitogen-activated protein kinase activation

Shock

Volumn 43, Issue 4, 2015, Pages 395-404

  Li, Yingchuan ^a   Zeng, Zhen ^a   Li, Yachun ^a   Huang, Weifeng ^a   Zhou, Ming ^a   Zhang, Xiaoli ^a   Jiang, Wei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Acute lung injury; Angiotensin converting enzyme; Captopril; Lipopolysaccharide; Mitogen activated protein kinases

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; ANGIOTENSIN[1-7]; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MLN 4760; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2-(1-CARBOXY-2-(3-(3,5-DICHLOROBENZYL)-3H-IMIDAZOL-4-YL)ETHYLAMINO)-4-METHYLPENTANOIC ACID; IMIDAZOLE DERIVATIVE; LEUCINE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; GENE EXPRESSION; IN VITRO STUDY; LUNG PARENCHYMA; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN PHOSPHORYLATION; PULMONARY MICROVASCULAR ENDOTHELIAL CELL; RAT; ANALOGS AND DERIVATIVES; ANIMAL; CELL SURVIVAL; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; LUNG INJURY; MALE; METABOLISM; MICROCIRCULATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CAPTOPRIL; CELL SURVIVAL; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; IMIDAZOLES; INTERLEUKIN-6; LEUCINE; LIPOPOLYSACCHARIDES; LUNG INJURY; MALE; MAP KINASE SIGNALING SYSTEM; MICROCIRCULATION; PEPTIDYL-DIPEPTIDASE A; RATS; RATS, SPRAGUE-DAWLEY; RENIN-ANGIOTENSIN SYSTEM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84924853970     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000302     Document Type: Article

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