Losartan prevents sepsis-induced acute lung injury and decreases activation of nuclear factorκB and mitogen-activated protein kinases

Shock

Volumn 31, Issue 5, 2009, Pages 500-506

  Shen, Lihan ^a   Mo, Hongying ^a   Cai, Lin ^a   Kong, Tianhan ^b   Zheng, Weihao ^a   Ye, Jihui ^a   Qi, Junhua ^b   Xiao, Zhenglun ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b Department of Guangzhou Research Institute of Snake Venom ^*  (China)

Author keywords

Angiotensin II; ARDS; MAPK; NF B; Renin angiotensin system; Signal transduction

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; ANGIOTENSIN RECEPTOR ANTAGONIST;

ACUTE LUNG INJURY; ACUTE RESPIRATORY TRACT DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD GAS; CECUM; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HISTOPATHOLOGY; LIGATION; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PROTECTION; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SEPSIS; SURVIVAL; ANIMAL; BAGG ALBINO MOUSE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; WESTERN BLOTTING;

ACUTE LUNG INJURY; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BLOTTING, WESTERN; INTERLEUKIN-1BETA; INTERLEUKIN-6; LOSARTAN; MALE; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHORYLATION; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649383521     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318189017a     Document Type: Article

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