Impaired attention and synaptic senescence of the prefrontal cortex involves redox regulation of NMDA receptors

Journal of Neuroscience

Volumn 35, Issue 9, 2015, Pages 3966-3977

  Guidi, Michael ^a   Kumar, Ashok ^a   Foster, Thomas C ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Aging; Attention; Executive function; NMDA receptor; Prefrontal cortex; Redox state

Indexed keywords

DITHIOTHREITOL; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POSTSYNAPTIC DENSITY PROTEIN 95;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSOCIATION; ATTENTION; BRAIN DEPTH STIMULATION; BRAIN ELECTROPHYSIOLOGY; DECISION MAKING; EXECUTIVE FUNCTION; EXPERIMENTAL BEHAVIORAL TEST; EXTRACELLULAR FIELD POTENTIAL RECORDING; HIPPOCAMPUS; LATENT PERIOD; MALE; METABOLIC REGULATION; MIDDLE AGED; NONHUMAN; OXIDATION REDUCTION STATE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SENESCENCE; SENSORIMOTOR FUNCTION; SYNAPSE; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION; TASK PERFORMANCE; TRAINING; WESTERN BLOTTING; ANIMAL; EXCITATORY POSTSYNAPTIC POTENTIAL; FISCHER 344 RAT; GROWTH, DEVELOPMENT AND AGING; LEARNING; OXIDATION REDUCTION REACTION; PHYSIOLOGY; REACTION TIME;

AGING; ANIMALS; ATTENTION; CUES; EXCITATORY POSTSYNAPTIC POTENTIALS; MALE; OXIDATION-REDUCTION; PREFRONTAL CORTEX; RATS; RATS, INBRED F344; REACTION TIME; RECEPTORS, N-METHYL-D-ASPARTATE; SERIAL LEARNING; SYNAPSES;

EID: 84924777565     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3523-14.2015     Document Type: Article

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