Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses

Molecular Carcinogenesis

Volumn 54, Issue 4, 2015, Pages 291-300

  Shrotriya, Sangeeta ^a   Tyagi, Alpna ^a   Deep, Gagan ^a,b   Orlicky, David J ^c   Wisell, Joshua ^c   Wang, Xiao Jing ^b,c   Sclafani, Robert A ^b,c   Agarwal, Rajesh ^a,b   Agarwal, Chapla ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

AMPK; Biomarkers; Chemoprevention; Head and neck squamous cell carcinoma; Tumor progression

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; ADENYLATE KINASE; BROXURIDINE; GRAPE SEED EXTRACT; PROTEIN P62; RESVERATROL; THREONINE; ANTINEOPLASTIC AGENT; CARCINOGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; STILBENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CARCINOGENESIS; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG MECHANISM; DYSPLASIA; ENZYME ACTIVATION; FEMALE; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; INCIDENCE; LABELING INDEX; MOUSE; NICK END LABELING; NONHUMAN; PRECANCER; PRIORITY JOURNAL; TONGUE CANCER; TONGUE TUMORIGENESIS; ANIMAL; C57BL MOUSE; CARCINOMA, SQUAMOUS CELL; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PATHOLOGY; TONGUE; TONGUE NEOPLASMS; TUNEL ASSAY;

MUS; VITACEAE;

4-NITROQUINOLINE-1-OXIDE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; CARCINOGENESIS; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; FEMALE; GRAPE SEED EXTRACT; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; STILBENES; TONGUE; TONGUE NEOPLASMS;

EID: 84924763597     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22099     Document Type: Article

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