메뉴 건너뛰기




Volumn 22, Issue 6, 2009, Pages 1277-1282

Genetic and molecular alterations associated with oral squamous cell cancer (Review)

Author keywords

Methylation; Oncogenes; Oral squamous cell carcinoma; Tumor suppressor genes

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; HLA B35 ANTIGEN; MEMBRANE ANTIGEN; PROTEIN P53; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A;

EID: 70449363866     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000565     Document Type: Review
Times cited : (103)

References (64)
  • 2
    • 0024010601 scopus 로고
    • Mechanisms of carcinogenesis with particular reference to the oral mucosa
    • Boyd NM and Reade PC: Mechanisms of carcinogenesis with particular reference to the oral mucosa. J Oral Pathol 17: 193-201, 1988.
    • (1988) J Oral Pathol , vol.17 , pp. 193-201
    • Boyd, N.M.1    Reade, P.C.2
  • 3
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D and Weinberg RA: The hallmarks of cancer. Cell 100: 57-70, 2000.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 84984934477 scopus 로고    scopus 로고
    • Expression profiling using cDNA microarrays
    • Duggan DJ, Bittner M, Chen Y, et al: Expression profiling using cDNA microarrays. Nat Genet 21: 10-14, 1999.
    • (1999) Nat Genet , vol.21 , pp. 10-14
    • Duggan, D.J.1    Bittner, M.2    Chen, Y.3
  • 5
    • 0035057561 scopus 로고    scopus 로고
    • Validation of array-based gene expression profiles by real-time (kinetic) RT-PCR
    • Rajeevan MS, Vernon SD, Taysavang N, et al: Validation of array-based gene expression profiles by real-time (kinetic) RT-PCR. J Mol Diagn 3: 26-31, 2001.
    • (2001) J Mol Diagn , vol.3 , pp. 26-31
    • Rajeevan, M.S.1    Vernon, S.D.2    Taysavang, N.3
  • 6
    • 15744381713 scopus 로고
    • Kinetic PCR analysis: Real-time monitoring of DNA amplification reactions
    • Higuchi R, Fockler C, Dollinger G and Watson R: Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (NY) 11: 1026-1030, 1993.
    • (1993) Biotechnology (NY) , vol.11 , pp. 1026-1030
    • Higuchi, R.1    Fockler, C.2    Dollinger, G.3    Watson, R.4
  • 7
    • 0031022694 scopus 로고    scopus 로고
    • Continuous fluorescence monitoring of rapid cycle DNA amplification
    • Wittwer CT, Herrmann MG, Moss AA and Rasmussen RP: Continuous fluorescence monitoring of rapid cycle DNA amplification. Biotechniques 22: 130-131, 134-138, 1997.
    • (1997) Biotechniques , vol.22 , Issue.130-131 , pp. 134-138
    • Wittwer, C.T.1    Herrmann, M.G.2    Moss, A.A.3    Rasmussen, R.P.4
  • 8
    • 0035959741 scopus 로고    scopus 로고
    • Oral cancer in vivo gene expression profiling assisted by laser capture microdissection and microarray analysis
    • Alevizos I, Mahadevappa M, Zhang X, et al: Oral cancer in vivo gene expression profiling assisted by laser capture microdissection and microarray analysis. Oncogene 20: 6196-6204, 2001.
    • (2001) Oncogene , vol.20 , pp. 6196-6204
    • Alevizos, I.1    Mahadevappa, M.2    Zhang, X.3
  • 9
    • 0037129361 scopus 로고    scopus 로고
    • Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells
    • Al Moustafa AE, Alaoui-Jamali MA, Batist G, et al: Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells. Oncogene 21: 2634-2640, 2002.
    • (2002) Oncogene , vol.21 , pp. 2634-2640
    • Al Moustafa, A.E.1    Alaoui-Jamali, M.A.2    Batist, G.3
  • 10
    • 19244367006 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in human salivary gland tumors by DNA microarrays
    • Francioso F, Carinci F, Tosi L, et al: Identification of differentially expressed genes in human salivary gland tumors by DNA microarrays. Mol Cancer Ther 1: 533-538, 2002.
    • (2002) Mol Cancer Ther , vol.1 , pp. 533-538
    • Francioso, F.1    Carinci, F.2    Tosi, L.3
  • 11
    • 0036023456 scopus 로고    scopus 로고
    • Gene expression profiling of advanced head and neck squamous cell carcinomas and two squamous cell carcinoma cell lines under radio/chemotherapy using cDNA arrays
    • Hartmann KA, Modlich O, Prisack HB, et al: Gene expression profiling of advanced head and neck squamous cell carcinomas and two squamous cell carcinoma cell lines under radio/chemotherapy using cDNA arrays. Radiother Oncol 63: 309-320, 2002.
    • (2002) Radiother Oncol , vol.63 , pp. 309-320
    • Hartmann, K.A.1    Modlich, O.2    Prisack, H.B.3
  • 12
    • 0037108186 scopus 로고    scopus 로고
    • A lymph node metastatic mouse model reveals alterations of metastasis-related gene expression in metastatic human oral carcinoma sublines selected from a poorly metastatic parental cell line
    • Zhang X, Liu Y, Gilcrease MZ, Yuan, et al: A lymph node metastatic mouse model reveals alterations of metastasis-related gene expression in metastatic human oral carcinoma sublines selected from a poorly metastatic parental cell line. Cancer 95: 1663-1672, 2002.
    • (2002) Cancer , vol.95 , pp. 1663-1672
    • Zhang, X.1    Liu, Y.2    Gilcrease, M.Z.3    Yuan4
  • 13
    • 0036786327 scopus 로고    scopus 로고
    • Transcriptional expression profiles of oral squamous cell carcinomas
    • Mendez E, Cheng C, Farwell DG, et al: Transcriptional expression profiles of oral squamous cell carcinomas. Cancer 95: 1482-1494, 2002.
    • (2002) Cancer , vol.95 , pp. 1482-1494
    • Mendez, E.1    Cheng, C.2    Farwell, D.G.3
  • 14
    • 0037210621 scopus 로고    scopus 로고
    • Ibrahim SO, Aarsaether N, Holsve MK, et al: Gene expression profile in oral squamous cell carcinomas and matching normal oral mucosal tissues from black Africans and white Caucasians: the case of the Sudan vs. Norway. Oral Oncol 39: 37-48, 2003.
    • Ibrahim SO, Aarsaether N, Holsve MK, et al: Gene expression profile in oral squamous cell carcinomas and matching normal oral mucosal tissues from black Africans and white Caucasians: the case of the Sudan vs. Norway. Oral Oncol 39: 37-48, 2003.
  • 15
    • 0038604838 scopus 로고    scopus 로고
    • Classification and identification of genes associated with oral cancer based on gene expression profiles. A preliminary study
    • Kuo WP, Hasina R, Ohno-Machado L and Lingen MW: Classification and identification of genes associated with oral cancer based on gene expression profiles. A preliminary study. N Y State Dent J 69: 23-26, 2003.
    • (2003) N Y State Dent J , vol.69 , pp. 23-26
    • Kuo, W.P.1    Hasina, R.2    Ohno-Machado, L.3    Lingen, M.W.4
  • 16
    • 0037399879 scopus 로고    scopus 로고
    • Genomic dissection for characterization of cancerous oral epithelium tissues using transcription profiling
    • Hwang D, Alevizos I, Schmitt WA, et al: Genomic dissection for characterization of cancerous oral epithelium tissues using transcription profiling. Oral Oncol 39: 259-268, 2003.
    • (2003) Oral Oncol , vol.39 , pp. 259-268
    • Hwang, D.1    Alevizos, I.2    Schmitt, W.A.3
  • 17
    • 0041522501 scopus 로고    scopus 로고
    • Identification of potential biomarkers of lymph node metastasis in oral squamous cell carcinoma by cDNA microarray analysis
    • Nagata M, Fujita H, Ida H, et al: Identification of potential biomarkers of lymph node metastasis in oral squamous cell carcinoma by cDNA microarray analysis. Int J Cancer 106: 683-689, 2003.
    • (2003) Int J Cancer , vol.106 , pp. 683-689
    • Nagata, M.1    Fujita, H.2    Ida, H.3
  • 18
    • 33646682821 scopus 로고    scopus 로고
    • Disease mechanism and biomarkers of oral squamous cell carcinoma
    • Brinkman BM and Wong DT: Disease mechanism and biomarkers of oral squamous cell carcinoma. Curr Opin Oncol 18: 228-233, 2006.
    • (2006) Curr Opin Oncol , vol.18 , pp. 228-233
    • Brinkman, B.M.1    Wong, D.T.2
  • 19
    • 33750704289 scopus 로고    scopus 로고
    • Identification of a gene signature for rapid screening of oral squamous cell carcinoma
    • Ziober AF, Patel KR, Alawi F, et al: Identification of a gene signature for rapid screening of oral squamous cell carcinoma. Clin Cancer Res 12: 5960-5971, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 5960-5971
    • Ziober, A.F.1    Patel, K.R.2    Alawi, F.3
  • 20
    • 34147163862 scopus 로고    scopus 로고
    • Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma
    • Nguyen ST, Hasegawa S, Tsuda H, et al: Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma. Cancer Sci 98: 740-746, 2007.
    • (2007) Cancer Sci , vol.98 , pp. 740-746
    • Nguyen, S.T.1    Hasegawa, S.2    Tsuda, H.3
  • 21
    • 33846295585 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas
    • Martinez I, Wang J, Hobson KF, et al: Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas. Eur J Cancer 43: 415-432, 2007.
    • (2007) Eur J Cancer , vol.43 , pp. 415-432
    • Martinez, I.1    Wang, J.2    Hobson, K.F.3
  • 22
    • 20144386704 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): Overexpression of NPM, CDK1 and NDRG1 and under-expression of CHES1
    • Chang JT, Wang HM, Chang KW, et al: Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): overexpression of NPM, CDK1 and NDRG1 and under-expression of CHES1. Int J Cancer 114: 942-949, 2005.
    • (2005) Int J Cancer , vol.114 , pp. 942-949
    • Chang, J.T.1    Wang, H.M.2    Chang, K.W.3
  • 23
    • 12544256773 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in oral squamous cell carcinoma
    • Arora S, Matta A, Shukla NK, et al: Identification of differentially expressed genes in oral squamous cell carcinoma. Mol Carcinog 42: 97-108, 2005.
    • (2005) Mol Carcinog , vol.42 , pp. 97-108
    • Arora, S.1    Matta, A.2    Shukla, N.K.3
  • 24
    • 4544287424 scopus 로고    scopus 로고
    • Global gene expression profiles of human head and neck squamous carcinoma cell lines
    • Jeon GA, Lee JS, Patel V, et al: Global gene expression profiles of human head and neck squamous carcinoma cell lines. Int J Cancer 112: 249-258, 2004.
    • (2004) Int J Cancer , vol.112 , pp. 249-258
    • Jeon, G.A.1    Lee, J.S.2    Patel, V.3
  • 25
    • 1642494850 scopus 로고    scopus 로고
    • Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck
    • Ginos MA, Page GP, Michalowicz BS, et al: Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck. Cancer Res 64: 55-63, 2004.
    • (2004) Cancer Res , vol.64 , pp. 55-63
    • Ginos, M.A.1    Page, G.P.2    Michalowicz, B.S.3
  • 26
    • 0038164876 scopus 로고    scopus 로고
    • Identification of 9 genes differentially expressed in head and neck squamous cell carcinoma
    • Gonzalez HE, Gujrati M, Frederick M, et al: Identification of 9 genes differentially expressed in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 129: 754-759, 2003.
    • (2003) Arch Otolaryngol Head Neck Surg , vol.129 , pp. 754-759
    • Gonzalez, H.E.1    Gujrati, M.2    Frederick, M.3
  • 27
    • 0347927487 scopus 로고    scopus 로고
    • Gene discovery in oral squamous cell carcinoma through the Head and Neck Cancer Genome Anatomy Project: Confirmation by microarray analysis
    • Leethanakul C, Knezevic V, Patel V, et al: Gene discovery in oral squamous cell carcinoma through the Head and Neck Cancer Genome Anatomy Project: confirmation by microarray analysis. Oral Oncol 39: 248-258, 2003.
    • (2003) Oral Oncol , vol.39 , pp. 248-258
    • Leethanakul, C.1    Knezevic, V.2    Patel, V.3
  • 28
    • 25444435694 scopus 로고    scopus 로고
    • Gene expression profile of cervical tissue compared to exfoliated cells: Impact on biomarker discovery
    • Steinau M, Lee DR, Rajeevan MS, et al: Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discovery. BMC Genomics 6: 64, 2005.
    • (2005) BMC Genomics , vol.6 , pp. 64
    • Steinau, M.1    Lee, D.R.2    Rajeevan, M.S.3
  • 29
    • 38149007268 scopus 로고    scopus 로고
    • Molecular pathogenesis of oral squamous cell carcinoma: Implications for therapy
    • Choi S and Myers JN: Molecular pathogenesis of oral squamous cell carcinoma: implications for therapy. J Dent Res 87: 14-32, 2008.
    • (2008) J Dent Res , vol.87 , pp. 14-32
    • Choi, S.1    Myers, J.N.2
  • 31
    • 34548462222 scopus 로고    scopus 로고
    • Clinicopathologic significance of EpCAM expression in squamous cell carcinoma of the tongue and its possibility as a potential target for tongue cancer gene therapy
    • Yanamoto S, Kawasaki G, Yoshitomi I, et al: Clinicopathologic significance of EpCAM expression in squamous cell carcinoma of the tongue and its possibility as a potential target for tongue cancer gene therapy. Oral Oncol 43: 869-877, 2007.
    • (2007) Oral Oncol , vol.43 , pp. 869-877
    • Yanamoto, S.1    Kawasaki, G.2    Yoshitomi, I.3
  • 32
    • 0035040893 scopus 로고    scopus 로고
    • Homozygous deletions on the short arm of chromosome 3 in human oral squamous cell carcinomas
    • Uzawa N, Akanuma D, Negishi A, et al: Homozygous deletions on the short arm of chromosome 3 in human oral squamous cell carcinomas. Oral Oncol 37: 351-356, 2001.
    • (2001) Oral Oncol , vol.37 , pp. 351-356
    • Uzawa, N.1    Akanuma, D.2    Negishi, A.3
  • 33
    • 42049095049 scopus 로고    scopus 로고
    • Losses of 3p14 and 9p21 as shown by fluorescence in situ hybridization are early events in tumorigenesis of oral squamous cell carcinoma and already occur in simple keratosis
    • Schwarz S, Bier J, Driemel O, et al: Losses of 3p14 and 9p21 as shown by fluorescence in situ hybridization are early events in tumorigenesis of oral squamous cell carcinoma and already occur in simple keratosis. Cytometry A 73: 305-311, 2008.
    • (2008) Cytometry A , vol.73 , pp. 305-311
    • Schwarz, S.1    Bier, J.2    Driemel, O.3
  • 34
    • 0029061585 scopus 로고
    • Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma
    • El-Naggar AK, Hurr K, Batsakis JG, et al: Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma. Cancer Res 55: 2656-2659, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2656-2659
    • El-Naggar, A.K.1    Hurr, K.2    Batsakis, J.G.3
  • 35
    • 57649230131 scopus 로고    scopus 로고
    • Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma
    • Ohta S, Uemura H, Matsui Y, et al: Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107: 81-91, 2009.
    • (2009) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.107 , pp. 81-91
    • Ohta, S.1    Uemura, H.2    Matsui, Y.3
  • 36
    • 0344586773 scopus 로고    scopus 로고
    • Loss of 9p21 is embedded in a complex but consistent pattern of genomic imbalances in oral squamous cell carcinomas
    • Gebhart E, Liehr T, Wolff E, et al: Loss of 9p21 is embedded in a complex but consistent pattern of genomic imbalances in oral squamous cell carcinomas. Cytogenet Genome Res 101: 106-112, 2003.
    • (2003) Cytogenet Genome Res , vol.101 , pp. 106-112
    • Gebhart, E.1    Liehr, T.2    Wolff, E.3
  • 38
    • 0033064227 scopus 로고    scopus 로고
    • Towards a molecular phototyping system for allelic variants of MICA, encoded by polymorphisms in exons 2, 3 and 4 of MHC class I chain-related genes
    • Stephens HA, Vaughan RW, Collins R, et al: Towards a molecular phototyping system for allelic variants of MICA, encoded by polymorphisms in exons 2, 3 and 4 of MHC class I chain-related genes. Tissue Antigens 53: 167-174, 1999.
    • (1999) Tissue Antigens , vol.53 , pp. 167-174
    • Stephens, H.A.1    Vaughan, R.W.2    Collins, R.3
  • 40
    • 33846252746 scopus 로고    scopus 로고
    • Mechanisms of EGFR gene transcription modulation: Relationship to cancer risk and therapy response
    • Brandt B, Meyer-Staeckling S, Schmidt H, et al: Mechanisms of EGFR gene transcription modulation: relationship to cancer risk and therapy response. Clin Cancer Res 12: 7252-7260, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 7252-7260
    • Brandt, B.1    Meyer-Staeckling, S.2    Schmidt, H.3
  • 41
    • 42949097680 scopus 로고    scopus 로고
    • ErbB2 and fatty acid synthase (FAS) expression in 102 squamous cell carcinomas of the tongue: Correlation with clinical outcomes
    • Silva SD, Perez DE, Alves FA, et al: ErbB2 and fatty acid synthase (FAS) expression in 102 squamous cell carcinomas of the tongue: correlation with clinical outcomes. Oral Oncol 44: 484-490, 2008.
    • (2008) Oral Oncol , vol.44 , pp. 484-490
    • Silva, S.D.1    Perez, D.E.2    Alves, F.A.3
  • 42
    • 2342582224 scopus 로고    scopus 로고
    • Pharmacodiagnostic value of the HER family in head and neck squamous cell carcinoma
    • Schartinger VH, Kacani L, Andrle J, et al: Pharmacodiagnostic value of the HER family in head and neck squamous cell carcinoma. ORL J Otorhinolaryngol Relat Spec 66: 21-26, 2004.
    • (2004) ORL J Otorhinolaryngol Relat Spec , vol.66 , pp. 21-26
    • Schartinger, V.H.1    Kacani, L.2    Andrle, J.3
  • 43
    • 34547731920 scopus 로고    scopus 로고
    • Diabetes increases both N-ras and ets-1 expression during rat oral oncogenesis resulting in enhanced cell proliferation and metastatic potential
    • Vairaktaris E, Goutzanis L, Kalokerinos G, et al: Diabetes increases both N-ras and ets-1 expression during rat oral oncogenesis resulting in enhanced cell proliferation and metastatic potential. In Vivo 21: 615-621, 2007.
    • (2007) In Vivo , vol.21 , pp. 615-621
    • Vairaktaris, E.1    Goutzanis, L.2    Kalokerinos, G.3
  • 44
    • 58249094168 scopus 로고    scopus 로고
    • Inhibition of cyclin D1 expression by cyclin D1 shRNAs in human oral squamous cell carcinoma cells is associated with increased cisplatin chemo-sensitivity
    • Zhou X, Zhang Z, Yang X, et al: Inhibition of cyclin D1 expression by cyclin D1 shRNAs in human oral squamous cell carcinoma cells is associated with increased cisplatin chemo-sensitivity. Int J Cancer 124: 483-489, 2009.
    • (2009) Int J Cancer , vol.124 , pp. 483-489
    • Zhou, X.1    Zhang, Z.2    Yang, X.3
  • 45
    • 45249104366 scopus 로고    scopus 로고
    • CCND1 polymorphisms (A870G and C1722G) modulate its protein expression and survival in oral carcinoma
    • Sathyan KM, Nalinakumari KR, Abraham T and Kannan S: CCND1 polymorphisms (A870G and C1722G) modulate its protein expression and survival in oral carcinoma. Oral Oncol 44: 689-697, 2008.
    • (2008) Oral Oncol , vol.44 , pp. 689-697
    • Sathyan, K.M.1    Nalinakumari, K.R.2    Abraham, T.3    Kannan, S.4
  • 46
    • 42249115842 scopus 로고    scopus 로고
    • A genotype-phenotype examination of cyclin D1 on risk and outcome of squamous cell carcinoma of the head and neck
    • Marsit CJ, Black CC, Posner MR and Kelsey KT: A genotype-phenotype examination of cyclin D1 on risk and outcome of squamous cell carcinoma of the head and neck. Clin Cancer Res 14: 2371-2377, 2008.
    • (2008) Clin Cancer Res , vol.14 , pp. 2371-2377
    • Marsit, C.J.1    Black, C.C.2    Posner, M.R.3    Kelsey, K.T.4
  • 47
    • 39149098856 scopus 로고    scopus 로고
    • Prognostic significance of TP53 mutations in oral squamous cell carcinoma with human papilloma virus infection
    • Kozomara RJ, Brankovic-Magic MV, Jovic NR, et al: Prognostic significance of TP53 mutations in oral squamous cell carcinoma with human papilloma virus infection. Int J Biol Markers 22: 252-257, 2007.
    • (2007) Int J Biol Markers , vol.22 , pp. 252-257
    • Kozomara, R.J.1    Brankovic-Magic, M.V.2    Jovic, N.R.3
  • 48
    • 0037105785 scopus 로고    scopus 로고
    • Alterations of p16(INK4a) and p14(ARF) in patients with severe oral epithelial dysplasia
    • Kresty LA, Mallery SR, Knobloch TJ, et al: Alterations of p16(INK4a) and p14(ARF) in patients with severe oral epithelial dysplasia. Cancer Res 62: 5295-5300, 2002.
    • (2002) Cancer Res , vol.62 , pp. 5295-5300
    • Kresty, L.A.1    Mallery, S.R.2    Knobloch, T.J.3
  • 49
    • 0034961861 scopus 로고    scopus 로고
    • Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas
    • Shintani S, Nakahara Y, Mihara M, et al: Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas. Oral Oncol 37: 498-504, 2001.
    • (2001) Oral Oncol , vol.37 , pp. 498-504
    • Shintani, S.1    Nakahara, Y.2    Mihara, M.3
  • 50
    • 0035155163 scopus 로고    scopus 로고
    • FHIT RNA and protein expression in oral squamous cell carcinomas
    • Van Heerden WF, Swart TJ, Robson B, et al: FHIT RNA and protein expression in oral squamous cell carcinomas. Anticancer Res 21: 2425-2428, 2001.
    • (2001) Anticancer Res , vol.21 , pp. 2425-2428
    • Van Heerden, W.F.1    Swart, T.J.2    Robson, B.3
  • 51
    • 0033230366 scopus 로고    scopus 로고
    • Immunohistochemical evaluation of Fhit protein expression in oral squamous cell carcinomas
    • Van Heerden WF, Swart TJ, van Heerden MB, et al: Immunohistochemical evaluation of Fhit protein expression in oral squamous cell carcinomas. J Oral Pathol Med 28: 433-437, 1999.
    • (1999) J Oral Pathol Med , vol.28 , pp. 433-437
    • Van Heerden, W.F.1    Swart, T.J.2    van Heerden, M.B.3
  • 52
    • 34748881761 scopus 로고    scopus 로고
    • Computer-assisted analysis of cell proliferation markers in oral lesions
    • Teresa DB, Neves KA, Neto CB and Fregonezi PA: Computer-assisted analysis of cell proliferation markers in oral lesions. Acta Histochem 109: 377-387, 2007.
    • (2007) Acta Histochem , vol.109 , pp. 377-387
    • Teresa, D.B.1    Neves, K.A.2    Neto, C.B.3    Fregonezi, P.A.4
  • 53
    • 0034162860 scopus 로고    scopus 로고
    • Experimental oral carcinoma of the tongue and buccal mucosa: Possible biologic markers linked to cancers at two anatomic sites
    • Schwartz JL, Gu X, Kittles RA, et al: Experimental oral carcinoma of the tongue and buccal mucosa: possible biologic markers linked to cancers at two anatomic sites. Oral Oncol 36: 225-235, 2000.
    • (2000) Oral Oncol , vol.36 , pp. 225-235
    • Schwartz, J.L.1    Gu, X.2    Kittles, R.A.3
  • 54
    • 38849141639 scopus 로고    scopus 로고
    • Intracellular pH regulation in oral squamous cell carcinoma is mediated by increased V-ATPase activity via over-expression of the ATP6V1C1 gene
    • Otero-Rey EM, Somoza-Martin M, Barros-Angueira F and Garcia-Garcia A: Intracellular pH regulation in oral squamous cell carcinoma is mediated by increased V-ATPase activity via over-expression of the ATP6V1C1 gene. Oral Oncol 44: 193-199, 2008.
    • (2008) Oral Oncol , vol.44 , pp. 193-199
    • Otero-Rey, E.M.1    Somoza-Martin, M.2    Barros-Angueira, F.3    Garcia-Garcia, A.4
  • 55
    • 43649098854 scopus 로고    scopus 로고
    • Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma
    • Imai T, Toyota M, Suzuki H, et al: Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma. Cancer Sci 99: 958-966, 2008.
    • (2008) Cancer Sci , vol.99 , pp. 958-966
    • Imai, T.1    Toyota, M.2    Suzuki, H.3
  • 56
    • 27744557989 scopus 로고    scopus 로고
    • Novel management of oral cancer: A paradigm of predictive oncology
    • Sudbo J: Novel management of oral cancer: a paradigm of predictive oncology. Clin Med Res 2: 233-242, 2004.
    • (2004) Clin Med Res , vol.2 , pp. 233-242
    • Sudbo, J.1
  • 57
    • 38649112304 scopus 로고    scopus 로고
    • TROP2: A novel prognostic marker in squamous cell carcinoma of the oral cavity
    • Fong D, Spizzo G, Gostner JM, et al: TROP2: a novel prognostic marker in squamous cell carcinoma of the oral cavity. Mod Pathol 21: 186-191, 2008.
    • (2008) Mod Pathol , vol.21 , pp. 186-191
    • Fong, D.1    Spizzo, G.2    Gostner, J.M.3
  • 58
    • 43549127319 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor (CTGF/CCN2) in head and neck squamous cell carcinoma
    • Mullis TC, Tang X and Chong KT: Expression of connective tissue growth factor (CTGF/CCN2) in head and neck squamous cell carcinoma. J Clin Pathol 61: 606-610, 2008.
    • (2008) J Clin Pathol , vol.61 , pp. 606-610
    • Mullis, T.C.1    Tang, X.2    Chong, K.T.3
  • 59
    • 33749020302 scopus 로고    scopus 로고
    • Validity of messenger RNA expression analyses of human saliva
    • Kumar SV, Hurteau GJ and Spivack SD: Validity of messenger RNA expression analyses of human saliva. Clin Cancer Res 12: 5033-5039, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 5033-5039
    • Kumar, S.V.1    Hurteau, G.J.2    Spivack, S.D.3
  • 60
    • 33846667831 scopus 로고    scopus 로고
    • Detection of serum Cyfra 21-1 in patients with primary oral squamous cell carcinoma
    • Zhong LP, Zhu HG, Zhang CP, et al: Detection of serum Cyfra 21-1 in patients with primary oral squamous cell carcinoma. Int J Oral Maxillofac Surg 36: 230-234, 2007.
    • (2007) Int J Oral Maxillofac Surg , vol.36 , pp. 230-234
    • Zhong, L.P.1    Zhu, H.G.2    Zhang, C.P.3
  • 61
    • 34848886852 scopus 로고    scopus 로고
    • Increased Cyfra 21-1 concentration in saliva from primary oral squamous cell carcinoma patients
    • Zhong LP, Zhang CP, Zheng JW, et al: Increased Cyfra 21-1 concentration in saliva from primary oral squamous cell carcinoma patients. Arch Oral Biol 52: 1079-1087, 2007.
    • (2007) Arch Oral Biol , vol.52 , pp. 1079-1087
    • Zhong, L.P.1    Zhang, C.P.2    Zheng, J.W.3
  • 62
    • 33846331272 scopus 로고    scopus 로고
    • Salivary analysis in oral cancer patients: DNA and protein oxidation, reactive nitrogen species, and antioxidant profile
    • Bahar G, Feinmesser R, Shpitzer T, et al: Salivary analysis in oral cancer patients: DNA and protein oxidation, reactive nitrogen species, and antioxidant profile. Cancer 109: 54-59, 2007.
    • (2007) Cancer , vol.109 , pp. 54-59
    • Bahar, G.1    Feinmesser, R.2    Shpitzer, T.3
  • 63
    • 42749093304 scopus 로고    scopus 로고
    • The expression of the receptor for glycation endproducts (RAGE) in oral squamous cell carcinomas
    • Landesberg R, Woo V, Huang L, et al: The expression of the receptor for glycation endproducts (RAGE) in oral squamous cell carcinomas. Oral Surg Oral Med Oral Patho Oral Radiol Endod 105: 617-624, 2008.
    • (2008) Oral Surg Oral Med Oral Patho Oral Radiol Endod , vol.105 , pp. 617-624
    • Landesberg, R.1    Woo, V.2    Huang, L.3
  • 64
    • 0036836089 scopus 로고    scopus 로고
    • Advances in the diagnosis of oral premalignant and malignant lesions
    • Epstein JB, Zhang L and Rosin M: Advances in the diagnosis of oral premalignant and malignant lesions. J Can Dent Assoc 68: 617-621, 2002.
    • (2002) J Can Dent Assoc , vol.68 , pp. 617-621
    • Epstein, J.B.1    Zhang, L.2    Rosin, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.