Molecular responses in the telomere-mitochondrial axis of ageing in the elderly: A candidate gene approach

Mechanisms of Ageing and Development

Volumn 145, Issue , 2015, Pages 51-57

  Pieters, Nicky ^a   Janssen, Bram G ^a   Valeri, Linda ^b   Cox, Bianca ^a   Cuypers, Ann ^a   Dewitte, Harrie ^c   Plusquin, Michelle ^a   Smeets, Karen ^a   Nawrot, Tim S ^a,d  

^a HASSELT UNIVERSITY   (Belgium)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c Primary Health Care Center GVHV   (Belgium)

^d Occupational and Environmental Medicine ^*  (Belgium)

Author keywords

Ageing; Mitochondrial DNA content; Targeted transcriptomics; Telomere length

Indexed keywords

MITOCHONDRIAL DNA; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; PROTEIN P53; SIRTUIN 1; TRANSCRIPTION FACTOR NRF2;

ADULT; AGED; AGING; ARTICLE; CORRELATION ANALYSIS; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; LEUKOCYTE; LEUKOCYTE TELOMERE LENGTH; MALE; MITOCHONDRION; NORMAL HUMAN; NRF1 GENE; NRF2 GENE; PGC 1ALPHA GENE; PGC 1BETA GENE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIRT1 GENE; SMOKING; TELOMERE HOMEOSTASIS; TUMOR SUPPRESSOR GENE; CLINICAL TRIAL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; TELOMERE;

AGED; AGING; DNA, MITOCHONDRIAL; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LEUKOCYTES; MALE; TELOMERE; TELOMERE HOMEOSTASIS;

EID: 84924756757     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2015.02.003     Document Type: Article

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