메뉴 건너뛰기




Volumn 17, Issue 2, 2015, Pages 253-260

Alterations of gene profiles in Leydig-cell-regenerating adult rat testis after ethane dimethane sulfonate-treatment

Author keywords

ethane dimethane sulfonate; gene profiling; Leydig cell; steroidogenesis

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450 1B1; CYTOCHROME P450 2A1; ETHYLENE GLYCOL DIMESYLATE; FATTY ACID BINDING PROTEIN; MESSENGER RNA; PROTEOLIPID PROTEIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; ANTISPERMATOGENIC AGENT; CYP2A1 PROTEIN, RAT; MESYLIC ACID DERIVATIVE; PKIB PROTEIN, RAT; SIGNAL PEPTIDE; STEROID MONOOXYGENASE; UNSPECIFIC MONOOXYGENASE;

EID: 84924727947     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.4103/1008-682X.136447     Document Type: Article
Times cited : (39)

References (42)
  • 2
    • 33644558342 scopus 로고    scopus 로고
    • In search of rat stem Leydig cells: Identification, isolation, and lineage-specific development
    • Ge RS, Dong Q, Sottas CM, Papadopoulos V, Zirkin BR, et al. In search of rat stem Leydig cells: identification, isolation, and lineage-specific development. Proc Natl Acad Sci U S A 2006; 103: 2719-24.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2719-2724
    • Ge, R.S.1    Dong, Q.2    Sottas, C.M.3    Papadopoulos, V.4    Zirkin, B.R.5
  • 3
    • 57749207570 scopus 로고    scopus 로고
    • Regulation of Leydig cells during pubertal development
    • Payne AH, Hardy MP, editors Totowa: Humana Press
    • Ge RS, Hardy MP. Regulation of Leydig cells during pubertal development. In: Payne AH, Hardy MP, editors. The Leydig Cell in Health and Disease. Totowa: Humana Press; 2007. p. 55-70.
    • (2007) The Leydig Cell in Health and Disease , pp. 55-70
    • Ge, R.S.1    Hardy, M.P.2
  • 6
    • 0031790274 scopus 로고    scopus 로고
    • Variation in the end products of androgen biosynthesis and metabolism during postnatal differentiation of rat Leydig cells
    • Ge RS, Hardy MP. Variation in the end products of androgen biosynthesis and metabolism during postnatal differentiation of rat Leydig cells. Endocrinology 1998; 139: 3787-95.
    • (1998) Endocrinology , vol.139 , pp. 3787-3795
    • Ge, R.S.1    Hardy, M.P.2
  • 7
    • 0024498263 scopus 로고
    • Kinetic studies on the development of the adult population of Leydig cells in testes of the pubertal rat
    • Hardy MP, Zirkin BR, Ewing LL. Kinetic studies on the development of the adult population of Leydig cells in testes of the pubertal rat. Endocrinology 1989; 124: 762-70.
    • (1989) Endocrinology , vol.124 , pp. 762-770
    • Hardy, M.P.1    Zirkin, B.R.2    Ewing, L.L.3
  • 8
    • 74949101637 scopus 로고    scopus 로고
    • 7alpha-hydroxytestosterone affects 1 beta-hydroxysteroid dehydrogenase 1 direction in rat Leydig cells
    • Hu GX, Lian QQ, Chen BB, Prasad PV, Kumar N, et al. 7alpha-hydroxytestosterone affects 1 beta-hydroxysteroid dehydrogenase 1 direction in rat Leydig cells. Endocrinology 2010; 151: 748-54.
    • (2010) Endocrinology , vol.151 , pp. 748-754
    • Hu, G.X.1    Lian, Q.Q.2    Chen, B.B.3    Prasad, P.V.4    Kumar, N.5
  • 9
    • 0023685339 scopus 로고
    • The regulation of the proliferation and differentiation of rat Leydig cell precursor cells after EDS administration or daily HCG treatment
    • Teerds KJ, De Rooij DG, Rommerts FF, Wensing CJ. The regulation of the proliferation and differentiation of rat Leydig cell precursor cells after EDS administration or daily HCG treatment. J Androl 1988; 9: 343-51.
    • (1988) J Androl , vol.9 , pp. 343-351
    • Teerds, K.J.1    De Rooij, D.G.2    Rommerts, F.F.3    Wensing, C.J.4
  • 10
    • 0025362321 scopus 로고
    • Development of a new Leydig cell population after the destruction of existing Leydig cells by ethane dimethane sulphonate in rats: An autoradiographic study
    • Teerds KJ, de Rooij DG, Rommerts FF, Wensing CJ. Development of a new Leydig cell population after the destruction of existing Leydig cells by ethane dimethane sulphonate in rats: an autoradiographic study. J Endocrinol 1990; 126: 229-36.
    • (1990) J Endocrinol , vol.126 , pp. 229-236
    • Teerds, K.J.1    De Rooij, D.G.2    Rommerts, F.F.3    Wensing, C.J.4
  • 11
    • 0033014725 scopus 로고    scopus 로고
    • Identification of markers for precursor and leydig cell differentiation in the adult rat testis following ethane dimethyl sulphonate administration
    • Teerds KJ, de Boer-Brouwer M, Dorrington JH, Balvers M, Ivell R. Identification of markers for precursor and leydig cell differentiation in the adult rat testis following ethane dimethyl sulphonate administration. Biol Reprod 1999; 60: 1437-45.
    • (1999) Biol Reprod , vol.60 , pp. 1437-1445
    • Teerds, K.J.1    De Boer-Brouwer, M.2    Dorrington, J.H.3    Balvers, M.4    Ivell, R.5
  • 12
    • 0035977842 scopus 로고    scopus 로고
    • Hormones and testis development and the possible adverse effects of environmental chemicals
    • Sharpe RM. Hormones and testis development and the possible adverse effects of environmental chemicals. Toxicol Lett 2001; 120: 221-32.
    • (2001) Toxicol Lett , vol.120 , pp. 221-232
    • Sharpe, R.M.1
  • 13
    • 0001935970 scopus 로고    scopus 로고
    • Regeneration of Leydig cells after depletion by EDS: A model for postnatal Leydig cell renewal
    • Payne AH, Hardy MP, Russell LD, editors Vienna, IL: Cache River Press
    • Teerds KJ. Regeneration of Leydig cells after depletion by EDS: a model for postnatal Leydig cell renewal. In: Payne AH, Hardy MP, Russell LD, editors. The Leydig Cell. Vienna, IL: Cache River Press; 1996. p. 203-20.
    • (1996) The Leydig Cell , pp. 203-220
    • Teerds, K.J.1
  • 14
    • 44449094728 scopus 로고    scopus 로고
    • Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero
    • Lin H, Ge RS, Chen GR, Hu GX, Dong L, et al. Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero. Proc Natl Acad Sci U S A 2008; 105: 7218-22.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 7218-7222
    • Lin, H.1    Ge, R.S.2    Chen, G.R.3    Hu, G.X.4    Dong, L.5
  • 15
    • 0019793063 scopus 로고
    • Serum levels of follicle stimulating hormone, luteinizing hormone, prolactin, testosterone, 5 alpha-dihydrotestosterone, 5 alpha-androstane-3 alpha, 17 beta-diol, 5 alpha-androstane-3 beta, 17 beta-diol, and 17 beta-estradiol from male beagles with spontaneous or induced benign prostatic hyperplasia
    • Cochran RC, Ewing LL, Niswender GD. Serum levels of follicle stimulating hormone, luteinizing hormone, prolactin, testosterone, 5 alpha-dihydrotestosterone, 5 alpha-androstane-3 alpha, 17 beta-diol, 5 alpha-androstane-3 beta, 17 beta-diol, and 17 beta-estradiol from male beagles with spontaneous or induced benign prostatic hyperplasia. Invest Urol 1981; 19: 142-7.
    • (1981) Invest Urol , vol.19 , pp. 142-147
    • Cochran, R.C.1    Ewing, L.L.2    Niswender, G.D.3
  • 16
    • 0242468437 scopus 로고    scopus 로고
    • Effects of insulin-like growth factor I on steroidogenic enzyme expression levels in mouse leydig cells
    • Wang GM, O'Shaughnessy PJ, Chubb C, Robaire B, Hardy MP. Effects of insulin-like growth factor I on steroidogenic enzyme expression levels in mouse leydig cells. Endocrinology 2003; 144: 5058-64.
    • (2003) Endocrinology , vol.144 , pp. 5058-5064
    • Wang, G.M.1    O'Shaughnessy, P.J.2    Chubb, C.3    Robaire, B.4    Hardy, M.P.5
  • 17
    • 1242298819 scopus 로고    scopus 로고
    • Development of leydig cells in the insulin-like growth factor-I (igf-I) knockout mouse: Effects of igf-I replacement and gonadotropic stimulation
    • Wang G, Hardy MP. Development of leydig cells in the insulin-like growth factor-I (igf-I) knockout mouse: effects of igf-I replacement and gonadotropic stimulation. Biol Reprod 2004; 70: 632-9.
    • (2004) Biol Reprod , vol.70 , pp. 632-639
    • Wang, G.1    Hardy, M.P.2
  • 18
    • 0024338398 scopus 로고
    • Corticosteroid 11 beta-dehydrogenase in rat testis
    • Phillips DM, Lakshmi V, Monder C. Corticosteroid 11 beta-dehydrogenase in rat testis. Endocrinology 1989; 125: 209-16.
    • (1989) Endocrinology , vol.125 , pp. 209-216
    • Phillips, D.M.1    Lakshmi, V.2    Monder, C.3
  • 19
    • 0030724858 scopus 로고    scopus 로고
    • Developmental changes in glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase oxidative and reductive activities in rat Leydig cells
    • Ge RS, Hardy DO, Catterall JF, Hardy MP. Developmental changes in glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase oxidative and reductive activities in rat Leydig cells. Endocrinology 1997; 138: 5089-95.
    • (1997) Endocrinology , vol.138 , pp. 5089-5095
    • Ge, R.S.1    Hardy, D.O.2    Catterall, J.F.3    Hardy, M.P.4
  • 20
    • 77953814972 scopus 로고    scopus 로고
    • Transcriptional profiling of luteinizing hormone receptor-deficient mice before and after testosterone treatment provides insight into the hormonal control of postnatal testicular development and Leydig cell differentiation
    • Griffin DK, Ellis PJ, Dunmore B, Bauer J, Abel MH, et al. Transcriptional profiling of luteinizing hormone receptor-deficient mice before and after testosterone treatment provides insight into the hormonal control of postnatal testicular development and Leydig cell differentiation. Biol Reprod 2010; 82: 1139-50.
    • (2010) Biol Reprod , vol.82 , pp. 1139-1150
    • Griffin, D.K.1    Ellis, P.J.2    Dunmore, B.3    Bauer, J.4    Abel, M.H.5
  • 21
    • 65949110564 scopus 로고    scopus 로고
    • In utero and lactational exposures to diethylhexyl-phthalate affect two populations of Leydig cells in male Long-Evans rats
    • Lin H, Lian QQ, Hu GX, Jin Y, Zhang Y, et al. In utero and lactational exposures to diethylhexyl-phthalate affect two populations of Leydig cells in male Long-Evans rats. Biol Reprod 2009; 80: 882-8.
    • (2009) Biol Reprod , vol.80 , pp. 882-888
    • Lin, H.1    Lian, Q.Q.2    Hu, G.X.3    Jin, Y.4    Zhang, Y.5
  • 22
    • 0036195674 scopus 로고    scopus 로고
    • Changes in Leydig cell gene expression during development in the mouse
    • O'Shaughnessy PJ, Willerton L, Baker PJ. Changes in Leydig cell gene expression during development in the mouse. Biol Reprod 2002; 66: 966-75.
    • (2002) Biol Reprod , vol.66 , pp. 966-975
    • O'Shaughnessy, P.J.1    Willerton, L.2    Baker, P.J.3
  • 23
    • 0029655550 scopus 로고    scopus 로고
    • Vitronectin in the cytoplasm of Leydig cells in the rat testis
    • Sawada H, Sugawara I, Kitami A, Hayashi M. Vitronectin in the cytoplasm of Leydig cells in the rat testis. Biol Reprod 1996; 54: 29-35.
    • (1996) Biol Reprod , vol.54 , pp. 29-35
    • Sawada, H.1    Sugawara, I.2    Kitami, A.3    Hayashi, M.4
  • 25
    • 0028839606 scopus 로고
    • Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action
    • Gnessi L, Emidi A, Jannini EA, Carosa E, Maroder M, et al. Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action. J Cell Biol 1995; 131: 1105-21.
    • (1995) J Cell Biol , vol.131 , pp. 1105-1121
    • Gnessi, L.1    Emidi, A.2    Jannini, E.A.3    Carosa, E.4    Maroder, M.5
  • 26
    • 0023682673 scopus 로고
    • Functional properties of developing rat Leydig cells after treatment with ethylene dimethanesulphonate (EDS)
    • Vreeburg JT, Ooms MP, Rommerts FF, Teerds KJ. Functional properties of developing rat Leydig cells after treatment with ethylene dimethanesulphonate (EDS). J Reprod Fertil 1988; 84: 63-9.
    • (1988) J Reprod Fertil , vol.84 , pp. 63-69
    • Vreeburg, J.T.1    Ooms, M.P.2    Rommerts, F.F.3    Teerds, K.J.4
  • 27
    • 2442490787 scopus 로고    scopus 로고
    • DD-RT-PCR identifies 7-dehydrocholesterol reductase as a key marker of early Leydig cell steroidogenesis
    • Anbalagan M, Yashwanth R, Jagannadha Rao A. DD-RT-PCR identifies 7-dehydrocholesterol reductase as a key marker of early Leydig cell steroidogenesis. Mol Cell Endocrinol 2004; 219: 37-45.
    • (2004) Mol Cell Endocrinol , vol.219 , pp. 37-45
    • Anbalagan, M.1    Yashwanth, R.2    Jagannadha Rao, A.3
  • 28
    • 77953591767 scopus 로고    scopus 로고
    • CYP1B1 expression in rat testis and Leydig cells is not inducible by aryl hydrocarbon receptor agonists
    • Deb S, Kawai M, Chang TK, Bandiera SM. CYP1B1 expression in rat testis and Leydig cells is not inducible by aryl hydrocarbon receptor agonists. Xenobiotica 2010; 40: 447-57.
    • (2010) Xenobiotica , vol.40 , pp. 447-457
    • Deb, S.1    Kawai, M.2    Chang, T.K.3    Bandiera, S.M.4
  • 29
    • 0037972887 scopus 로고    scopus 로고
    • Differentiation-dependent expression of 17beta-hydroxysteroid dehydrogenase, type 10, in the rodent testis: Effect of aging in Leydig cells
    • Ivell R, Balvers M, Anand RJ, Paust HJ, McKinnell C, et al. Differentiation-dependent expression of 17beta-hydroxysteroid dehydrogenase, type 10, in the rodent testis: effect of aging in Leydig cells. Endocrinology 2003; 144: 3130-7.
    • (2003) Endocrinology , vol.144 , pp. 3130-3137
    • Ivell, R.1    Balvers, M.2    Anand, R.J.3    Paust, H.J.4    McKinnell, C.5
  • 30
    • 0025723431 scopus 로고
    • Cellular localization of cytochrome P450IIA1 in testes of mature Sprague-Dawley rats
    • Seng JE, Leakey JE, Arlotto MP, Parkinson A, Gandy J. Cellular localization of cytochrome P450IIA1 in testes of mature Sprague-Dawley rats. Biol Reprod 1991; 45: 876-82.
    • (1991) Biol Reprod , vol.45 , pp. 876-882
    • Seng, J.E.1    Leakey, J.E.2    Arlotto, M.P.3    Parkinson, A.4    Gandy, J.5
  • 31
    • 0026325268 scopus 로고
    • Immunoreactive cytochrome P-450 (17 alpha) in rat and guinea-pig gonads, adrenal glands and brain
    • Le Goascogne C, Sananès N, Gouézou M, Takemori S, Kominami S, et al. Immunoreactive cytochrome P-450 (17 alpha) in rat and guinea-pig gonads, adrenal glands and brain. J Reprod Fertil 1991; 93: 609-22.
    • (1991) J Reprod Fertil , vol.93 , pp. 609-622
    • Le Goascogne, C.1    Sananès, N.2    Gouézou, M.3    Takemori, S.4    Kominami, S.5
  • 32
    • 0034194457 scopus 로고    scopus 로고
    • Absence of correlation between in situ expression of cytochrome P450 17alpha hydroxylase/lyase and 3beta-hydroxysteroid dehydrogenase/(Delta5-4) isomerase messenger ribonucleic acids and steroidogenesis during pubertal development in the rat testis
    • Mack SO, Garrett WM, Guthrie HD. Absence of correlation between in situ expression of cytochrome P450 17alpha hydroxylase/lyase and 3beta-hydroxysteroid dehydrogenase/(Delta5-4) isomerase messenger ribonucleic acids and steroidogenesis during pubertal development in the rat testis. J Steroid Biochem Mol Biol 2000; 73: 19-28.
    • (2000) J Steroid Biochem Mol Biol , vol.73 , pp. 19-28
    • Mack, S.O.1    Garrett, W.M.2    Guthrie, H.D.3
  • 33
    • 79955064344 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein is a useful marker for Leydig cells and sex-cord stromal tumors
    • Dong L, Wang H, Su Z, Niu S, Wang R, et al. Steroidogenic acute regulatory protein is a useful marker for Leydig cells and sex-cord stromal tumors. Appl Immunohistochem Mol Morphol 2011; 19: 226-32.
    • (2011) Appl Immunohistochem Mol Morphol , vol.19 , pp. 226-232
    • Dong, L.1    Wang, H.2    Su, Z.3    Niu, S.4    Wang, R.5
  • 34
    • 0033843856 scopus 로고    scopus 로고
    • Expression and regulation of connexin43 in rat Leydig cells
    • You S, Li W, Lin T. Expression and regulation of connexin43 in rat Leydig cells. J Endocrinol 2000; 166: 447-53.
    • (2000) J Endocrinol , vol.166 , pp. 447-453
    • You, S.1    Li, W.2    Lin, T.3
  • 35
    • 0033559336 scopus 로고    scopus 로고
    • Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: A control enzyme in ketogenesis
    • Hegardt FG. Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: a control enzyme in ketogenesis. Biochem J 1999; 338: 569-82.
    • (1999) Biochem J , vol.338 , pp. 569-582
    • Hegardt, F.G.1
  • 36
    • 0027404070 scopus 로고
    • Diazepam binding inhibitor is a paracrine/autocrine regulator of Leydig cell proliferation and steroidogenesis: Action via peripheral-type benzodiazepine receptor and independent mechanisms
    • Garnier M, Boujrad N, Oke BO, Brown AS, Riond J, et al. Diazepam binding inhibitor is a paracrine/autocrine regulator of Leydig cell proliferation and steroidogenesis: action via peripheral-type benzodiazepine receptor and independent mechanisms. Endocrinology 1993; 132: 444-58.
    • (1993) Endocrinology , vol.132 , pp. 444-458
    • Garnier, M.1    Boujrad, N.2    Oke, B.O.3    Brown, A.S.4    Riond, J.5
  • 37
    • 45249107787 scopus 로고    scopus 로고
    • Leydig cell re-generation and expression of cell signaling molecules in the germ cell-free testis
    • O'Shaughnessy PJ, Morris ID, Baker PJ. Leydig cell re-generation and expression of cell signaling molecules in the germ cell-free testis. Reproduction 2008; 135: 851-8.
    • (2008) Reproduction , vol.135 , pp. 851-858
    • O'Shaughnessy, P.J.1    Morris, I.D.2    Baker, P.J.3
  • 38
    • 0028107819 scopus 로고
    • Persistent expression of a truncated form of the luteinizing hormone receptor messenger ribonucleic acid in the rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate
    • Tena-Sempere M, Zhang FP, Huhtaniemi I. Persistent expression of a truncated form of the luteinizing hormone receptor messenger ribonucleic acid in the rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate. Endocrinology 1994; 135: 1018-24.
    • (1994) Endocrinology , vol.135 , pp. 1018-1024
    • Tena-Sempere, M.1    Zhang, F.P.2    Huhtaniemi, I.3
  • 39
    • 0034662155 scopus 로고    scopus 로고
    • Cloning and mapping of human PKIB and PKIG, and comparison of tissue expression patterns of three members of the protein kinase inhibitor family, including PKIA
    • Zheng L, Yu L, Tu Q, Zhang M, He H, et al. Cloning and mapping of human PKIB and PKIG, and comparison of tissue expression patterns of three members of the protein kinase inhibitor family, including PKIA. Biochem J 2000; 349: 403-7.
    • (2000) Biochem J , vol.349 , pp. 403-407
    • Zheng, L.1    Yu, L.2    Tu, Q.3    Zhang, M.4    He, H.5
  • 40
    • 68949098575 scopus 로고    scopus 로고
    • Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways
    • Chung S, Furihata M, Tamura K, Uemura M, Daigo Y, et al. Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways. Oncogene 2009; 28: 2849-59.
    • (2009) Oncogene , vol.28 , pp. 2849-2859
    • Chung, S.1    Furihata, M.2    Tamura, K.3    Uemura, M.4    Daigo, Y.5
  • 42
    • 0035704726 scopus 로고    scopus 로고
    • Degeneration and restoration of spermatogenesis in relation to the changes in Leydig cell population following ethane dimethanesulfonate treatment in adult rats
    • Bakalska M, Atanassova N, Angelova P, Koeva I, Nikolov B, et al. Degeneration and restoration of spermatogenesis in relation to the changes in Leydig cell population following ethane dimethanesulfonate treatment in adult rats. Endocr Regul 2001; 35: 209-15.
    • (2001) Endocr Regul , vol.35 , pp. 209-215
    • Bakalska, M.1    Atanassova, N.2    Angelova, P.3    Koeva, I.4    Nikolov, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.