Metabolites of 5F-AKB-48, a synthetic cannabinoid receptor agonist, identified in human urine and liver microsomal preparations using liquid chromatography high-resolution mass spectrometry

Drug Testing and Analysis

Volumn 7, Issue 3, 2015, Pages 199-206

  Holm, Niels Bjerre ^a   Pedersen, Anders Just ^a   Dalsgaard, Petur Weihe ^a   Linnet, Kristian ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

High resolution mass spectrometry; Human liver microsomes; Metabolites; Synthetic cannabinoids; Urine

Indexed keywords

BIOMOLECULES; BODY FLUIDS; COPYRIGHTS; DRUG PRODUCTS; FORENSIC SCIENCE; HYDROXYLATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

CANNABINOID RECEPTORS; CARBOXAMIDES; HIGH RESOLUTION MASS SPECTROMETRY; HUMAN LIVER; HUMAN LIVER MICROSOMES; HUMAN URINE; INDAZOLE; MICROSOMAL PREPARATIONS; SYNTHETIC CANNABINOID; URINE;

METABOLITES;

ADAMANTANE DERIVATIVE; AMIDE; CANNABINOID RECEPTOR AGONIST; DRUG METABOLITE; FLUORINE DERIVATIVE; HYDROXYL GROUP; INDAZOLE DERIVATIVE; N (1 ADAMANTYL) 1 (5 FLUOROPENTYL) 1H INDAZOLE 3 CARBOXAMIDE; UNCLASSIFIED DRUG; ADAMANTANE; DESIGNER DRUG; N-​(1-ADAMANT​YL)-​1-​(5-​FLUOROPENTYL)-​1H-​INDAZOLE-​3-​CARBOXAMIDE;

ARTICLE; CONTROLLED STUDY; DEALKYLATION; DEFLUORINATION; DIHYDROXYLATION; DRUG HYDROXYLATION; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG OXIDATION; FOURIER TRANSFORM MASS SPECTROMETRY; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MEASUREMENT ACCURACY; MONOHYDROXYLATION; PRIORITY JOURNAL; TRIHYDROXYLATION; URINE; ANALOGS AND DERIVATIVES; MASS SPECTROMETRY; METABOLISM; PROCEDURES;

ADAMANTANE; CANNABINOID RECEPTOR AGONISTS; CHROMATOGRAPHY, LIQUID; DESIGNER DRUGS; HUMANS; INDAZOLES; MASS SPECTROMETRY; MICROSOMES, LIVER;

EID: 84924726886     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.1663     Document Type: Article

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