Elevated gene expression of S100A12 is correlated with the predominant clinical inflammatory factors in patients with bacterial pneumonia

Molecular Medicine Reports

Volumn 11, Issue 6, 2015, Pages 4345-4352

  Hou, Fei ^a   Wang, Likui ^b   Wang, Hong ^a   Gu, Junchao ^a   Li, Meiling ^c   Zhang, Jingkai ^c   Ling, Xiao ^c   Gao, Xiaofang ^c   Luo, Cheng ^c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF MICROBIOLOGY   (China)

^c TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Heatmap; Inflammatory factor; Reverse transcription quantitative polymerase chain reaction; S100A12

Indexed keywords

ADENOSINE TRIPHOSPHATE; BECLIN 1; CURCUMIN; LIPOCORTIN 5; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BNIP3; PROTEIN LC3B I; PROTEIN LC3B II; SIRTUIN 1; UNCLASSIFIED DRUG; AUTACOID; CALGRANULIN C;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATPASE ACTIVITY ASSAY; AUTOPHAGY; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CURCUMA LONGA; MTT ASSAY; MUSCLE CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; WESTERN BLOTTING; ADULT; AGED; BACTERIAL PNEUMONIA; CASE CONTROL STUDY; CLUSTER ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; HUMAN; MALE; METABOLISM; MIDDLE AGED; RADIOGRAPHY; YOUNG ADULT;

BACTERIA (MICROORGANISMS);

ADULT; AGED; CASE-CONTROL STUDIES; CLUSTER ANALYSIS; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; PNEUMONIA, BACTERIAL; S100A12 PROTEIN; TOMOGRAPHY, X-RAY COMPUTED; YOUNG ADULT;

EID: 84924716436     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3295     Document Type: Article

References (40)

1. Maletzki C, Bodammer P, Breitruck A and Kerkhoff C: S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma. Hepat Mon 12: e7240, 2012.
2. Schafer BW, Wicki R, Engelkamp D, Mattei MG and Heizmann CW: Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. Genomics 25: 638-643, 1995.
3. Yamamura T, Hitomi J, Nagasaki K, et al: Human CAAF1 gene molecular cloning, gene structure, and chromosome mapping. Biochem Biophys Res Commun 221: 356-360, 1996.
4. Roth J, Vogl T, Sorg C and Sunderkotter C: Phagocyte-specific S100 proteins: a novel group of proinflammatory molecules. Trends Immunol 24: 155-158, 2003.
5. Guignard F, Mauel J and Markert M: Identification and characterization of a novel human neutrophil protein related to the S100 family. Biochem J 309: 395-401, 1995.
6. Marti T, Erttmann KD and Gallin MY: Host-parasite interaction in human onchocerciasis: identification and sequence analysis of a novel human calgranulin. Biochem Biophys Res Commun 221: 454-458, 1996.
7. Ryckman C, Robichaud GA, Roy J, Cantin R, Tremblay MJ and Tessier PA: HIV-1 transcription and virus production are both accentuated by the proinflammatory myeloid-related proteins in human CD4+ T lymphocytes. J Immunol 169: 3307-3313, 2002.
8. Moroz OV, Antson AA, Dodson GG, et al: Crystallization and preliminary X-ray diffraction analysis of human calcium-binding protein S100A12. Acta Crystallogr D Biol Crystallogr 56: 189-191, 2000.
9. Ilg EC, Troxler H, Burgisser DM, et al: Amino acid sequence determination of human S100A12 (P6, calgranulin C, CGRP, CAAF1) by tandem mass spectrometry. Biochem Biophys Res Commun 225: 146-150, 1996.
10. Cole AM, Kim YH, Tahk S, et al: Calcitermin, a novel antimicrobial peptide isolated from human airway secretions. FEBS Lett 504: 5-10, 2001.
11. Filipek A, Jastrzebska B, Nowotny M and Kuznicki J: CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family. J Biol Chem 277: 28848-28852, 2002.
12. Morbini P, Villa C, Campo I, Zorzetto M, Inghilleri S and Luisetti M: The receptor for advanced glycation end products and its ligands: a new inflammatory pathway in lung disease. Mod Pathol 19: 1437-1445, 2006.
13. Kikkawa T, Sato N, Kojika M, et al: Significance of measuring S100A12 and sRAGE in the serum of sepsis patients with postoperative acute lung injury. Dig Surg 27: 307-312, 2010.
14. Hofmann MA, Drury S, Fu C, et al: RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97: 889-901, 1999.
15. Moroz OV, Antson AA, Murshudov GN, et al: The three-dimensional structure of human S100A12. Acta Crystallogr D Biol Crystallogr 57: 20-29, 2001.
16. Moroz OV, Antson AA, Dodson EJ, et al: The structure of S100A12 in a hexameric form and its proposed role in receptor signalling. Acta Crystallogr D Biol Crystallogr 58: 407-413, 2002.
17. Machelska H, Schopohl JK, Mousa SA, Labuz D, Schafer M and Stein C: Different mechanisms of intrinsic pain inhibition in early and late inflammation. J Neuroimmunol 141: 30-39, 2003.
18. Stein C, Schafer M and Machelska H: Attacking pain at its source: new perspectives on opioids. Nat Med 9: 1003-1008, 2003.
19. Medzhitov R: Origin and physiological roles of inflammation. Nature 454: 428-435, 2008.
20. Spiekerkoetter E, Guignabert C, de Jesus Perez V, et al: S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4. Circ Res 105: 639-647, 2009.
21. Dabritz J, Langhorst J, Lugering A, et al: Improving relapse prediction in inflammatory bowel disease by neutrophil-derived S100A12. Inflamm Bowel Dis 19: 1130-1138, 2013.
22. Hofmann BMA, Heydemann A, Gawdzik J, Shilling RA and Camoretti-Mercado B: Transgenic expression of human S100A12 induces structural airway abnormalities and limited lung inflammation in a mouse model of allergic inflammation. Clin Exp Allergy 41: 878-889, 2011.
23. van Zoelen MA, Achouiti A and van der Poll T: RAGE during infectious diseases. Front Biosci (Schol Ed) 3: 1119-1132, 2011.
24. Batliwalla FM, Baechler EC, Xiao X, et al: Peripheral blood gene expression profiling in rheumatoid arthritis. Genes Immun 6: 388-397, 2005.
25. Das D, Gawdzik J, Dellefave-Castillo L, McNally EM, Husain A, et al: S100A12 expression in thoracic aortic aneurysm is associated with increased risk of dissection and perioperative complications. J Am Coll Cardiol 60: 775-785, 2012.
26. Brinar M, Cleynen I, Coopmans T, et al: Serum S100A12 as a new marker for inflammatory bowel disease and its relationship with disease activity. Gut 59: 1728-1729, 2010.
27. Dabritz J, Jenke A, Wirth S and Foell D: Fecal phagocyte-specific S100A12 for diagnosing necrotizing enterocolitis. J Pediatr 161: 1059-1064, 2012.
28. Nakashima M, Sakai T, Hiraiwa H, et al: Role of S100A12 in the pathogenesis of osteoarthritis. Biochem Biophys Res Commun 422: 508-514, 2012.
29. Foell D, Ichida F, Vogl T, et al: S100A12 (EN-RAGE) in monitoring Kawasaki disease. Lancet 361: 1270-1272, 2003.
30. Foell D, Kucharzik T, Kraft M, et al: Neutrophil derived human S100A12 (EN-RAGE) is strongly expressed during chronic active inflammatory bowel disease. Gut 52: 847-853, 2003.
31. Ginocchio CC, Lotlikar M, Falk L, et al: Clinical performance of the 3M Rapid Detection Flu A+B Test compared to R-Mix culture, DFA and BinaxNOW Influenza A&B Test. J Clin Virol 45: 146-149, 2009.
32. Rongeat N, Ledroit S, Chauvet L et al: Automatic cytometric device using multiple wavelength excitations. J Biomed Opt 16: 057006, 2011.
33. Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408, 2001.
34. Braun RP and Lee JS: Immunogenic duplex nucleic acids are nuclease resistant. J Immunol 141: 2084-2089, 1988.
35. Smyth GK: Limma: linear models for microarray data. In: Bioinformatics and Computational Biology Solutions using R and Bioconductor. Gentleman R, Carey V, Dudoit SR, Irizarry WH and Huber W (eds). Springer, New York, pp 397-420, 2005.
36. Pradeep AR, Martande SS, Singh SP, et al: Correlation of human S100A12 (EN-RAGE) and high-sensitivity C-reactive protein as gingival crevicular fluid and serum markers of inflammation in chronic periodontitis and type 2 diabetes. Inflamm Res 63: 317-323, 2014.
37. Dellinger RP, Levy MM, Rhodes A, et al: Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 39: 165-228, 2013.
38. Gaïni S, Koldkjaer OG, Pedersen C and Pedersen SS: Procalcitonin, lipopolysaccharide-binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis: a prospective study. Critical care 10: R53, 2006.
39. Ballou SP and Kushner I: C-reactive protein and the acute phase response. Adv Intern Med 37: 313-336, 1992.
40. Pietzsch J and Hoppmann S: Human S100A12: a novel key player in inflammation. Amino Acids 36: 381-389, 2009.