S100A12 expression in thoracic aortic aneurysm is associated with increased risk of dissection and perioperative complications

Journal of the American College of Cardiology

Volumn 60, Issue 8, 2012, Pages 775-785

  Das, Deepanjana ^a   Gawdzik, Joseph ^a   Dellefave Castillo, Lisa ^a   McNally, Elizabeth M ^a   Husain, Aliya ^a   Raman, Jai ^a   Hofmann Bowman, Marion A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

aortic smooth muscle cells; cell death; receptor for advanced glycation end products; S100 proteins; thoracic aortic aneurysm and dissection

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CALCIUM BINDING PROTEIN; CASPASE 3; MOLECULAR MARKER; MYELOPEROXIDASE; PROTEIN S100 A12; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ANEURYSM SURGERY; ANIMAL CELL; ANIMAL TISSUE; AORTA DISSECTING ANEURYSM; AORTA MEDIA; APOPTOSIS; ARTICLE; CELL CULTURE; ELECTIVE SURGERY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PERIOPERATIVE COMPLICATION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK ASSESSMENT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; THORACIC AORTA ANEURYSM;

ANEURYSM, DISSECTING; ANIMALS; AORTIC ANEURYSM, THORACIC; APOPTOSIS; CELLS, CULTURED; HUMANS; IMMUNOBLOTTING; IN SITU NICK-END LABELING; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; OXIDATIVE STRESS; PERIOPERATIVE PERIOD; POSTOPERATIVE COMPLICATIONS; RECEPTORS, IMMUNOLOGIC; RESEARCH DESIGN; S100 PROTEINS; SIGNAL TRANSDUCTION; UP-REGULATION; VASCULAR SURGICAL PROCEDURES;

EID: 84865137945     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2012.04.027     Document Type: Article

References (36)

1. L.F. Hiratzka, G.L. Bakris, J.A. Beckman 2010 ACCF/AHA/AATS/ACR/ASA/SCA/ SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine J Am Coll Cardiol 55 2010 e27 e129
2. M. Hofmann Bowman, J. Wilk, A. Heydemann S100A12 mediates aortic wall remodeling and aortic aneurysm Circ Res 106 2010 145 154
3. J.P. Habashi, D.P. Judge, T.M. Holm Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome Science 312 2006 117 121
4. M.A. Hofmann, S. Drury, C. Fu RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides Cell 97 1999 889 901 (Pubitemid 29375048)
5. M.A. Hofmann Bowman, J. Gawdzik, U. Bukhari S100A12 in vascular smooth muscle accelerates vascular calcification in apolipoprotein E-null mice by activating an osteogenic gene regulatory program Arterioscler Thromb Vasc Biol 31 2011 337 344
6. S. Rosenberg, M.R. Elashoff, P. Beineke Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients Ann Intern Med 153 2010 425 434
7. A.P. Burke, F.D. Kolodgie, A. Zieske Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study Arterioscler Thromb Vasc Biol 24 2004 1266 1271 (Pubitemid 38880019)
8. R. He, D.C. Guo, A.L. Estrera Characterization of the inflammatory and apoptotic cells in the aortas of patients with ascending thoracic aortic aneurysms and dissections J Thorac Cardiovasc Surg 131 2006 671 678
9. R. He, D.C. Guo, W. Sun Characterization of the inflammatory cells in ascending thoracic aortic aneurysms in patients with Marfan syndrome, familial thoracic aortic aneurysms, and sporadic aneurysms J Thorac Cardiovasc Surg 136 2008 922 929 929e1
10. W.C. Roberts, T.J. Vowels, J.M. Ko Comparison of the structure of the aortic valve and ascending aorta in adults having aortic valve replacement for aortic stenosis versus for pure aortic regurgitation and resection of the ascending aorta for aneurysm Circulation 123 2011 896 903
11. W.C. Roberts, T.J. Vowels, B.L. Kitchens Aortic medial elastic fiber loss in acute ascending aortic dissection Am J Cardiol 108 2011 1639 1644
12. S.A. Nashef, F. Roques, P. Michel, E. Gauducheau, S. Lemeshow, R. Salamon European system for cardiac operative risk evaluation (EuroSCORE) Eur J Cardiothorac Surg 16 1999 9 13 (Pubitemid 29336425)
13. T. Hasegawa, A. Kosaki, T. Kimura The regulation of EN-RAGE (S100A12) gene expression in human THP-1 macrophages Atherosclerosis 171 2003 211 218 (Pubitemid 37486072)
14. N. Mahajan, A. Bahl, V. Dhawan C-reactive protein (CRP) up-regulates expression of receptor for advanced glycation end products (RAGE) and its inflammatory ligand EN-RAGE in THP-1 cells: inhibitory effects of atorvastatin Int J Cardiol 142 2010 273 278
15. H. Chen, L. Cheng, S. Yang Molecular characterization, induced expression, and transcriptional regulation of porcine S100A12 gene Mol Immunol 47 2010 1601 1607
16. -/- mice J Clin Invest 118 2008 183 194
17. K. Loser, T. Vogl, M. Voskort The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells Nat Med 16 2010 713 717
18. J.D. Gottsch, S.W. Eisinger, S.H. Liu, A.L. Scott Calgranulin C has filariacidal and filariastatic activity Infect Immun 67 1999 6631 6636
19. S. Berthier, M.H. Paclet, S. Lerouge Changing the conformation state of cytochrome b558 initiates NADPH oxidase activation: MRP8/MRP14 regulation J Biol Chem 278 2003 25499 25508 (Pubitemid 36835301)
20. J. Gawdzik, L. Mathew, G. Kim, T.S. Puri, M.A. Hofmann Bowman Vascular remodeling and arterial calcification are directly mediated by S100A12 (EN-RAGE) in chronic kidney disease Am J Nephrol 33 2011 250 259
21. M.A. Hofmann Bowman, A. Heydemann, J. Gawdzik, R.A. Shilling, B. Camoretti-Mercado Transgenic expression of human S100A12 induces structural airway abnormalities and limited lung inflammation in a mouse model of allergic inflammation Clin Exp Allergy 41 2011 878 889
22. S. Yui, Y. Nakatani, M. Mikami Calprotectin (S100A8/S100A9), an inflammatory protein complex from neutrophils with a broad apoptosis-inducing activity Biol Pharm Bull 26 2003 753 760 (Pubitemid 39655290)
23. S. Ghavami, C. Kerkhoff, W.J. Chazin S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2 Biochim Biophys Acta 1783 2008 297 311
24. J.H. Boyd, B. Kan, H. Roberts, Y. Wang, K.R. Walley S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end products Circ Res 102 2008 1239 1246
25. J.N. Tsoporis, S. Izhar, H. Leong-Poi, J.F. Desjardins, H.J. Huttunen, T.G. Parker S100B interaction with the receptor for advanced glycation end products (RAGE): a novel receptor-mediated mechanism for myocyte apoptosis postinfarction Circ Res 106 2010 93 101
26. K. Croce, H. Gao, Y. Wang Myeloid-related protein-8/14 is critical for the biological response to vascular injury Circulation 120 2009 427 436
27. M.M. Averill, S. Barnhart, L. Becker S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation Circulation 123 2011 1216 1226
28. W. Lesniak Epigenetic regulation of S100 protein expression Clin Epigenetics 2 2011 77 83
29. K.L. Rock, E. Latz, F. Ontiveros, H. Kono The sterile inflammatory response Annu Rev Immunol 28 2010 321 342
30. T. Bergsbaken, S.L. Fink, B.T. Cookson Pyroptosis: host cell death and inflammation Nat Rev Microbiol 7 2009 99 109
31. S.S. Shaw, A.M. Schmidt, A.K. Banes, X. Wang, D.M. Stern, M.B. Marrero S100B-RAGE-mediated augmentation of angiotensin II-induced activation of JAK2 in vascular smooth muscle cells is dependent on PLD2 Diabetes 52 2003 2381 2388 (Pubitemid 37059510)
32. S.F. Yan, R. Ramasamy, A.M. Schmidt The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature Circ Res 106 2010 842 853
33. F. Zhang, K.C. Kent, D. Yamanouchi Anti-receptor for advanced glycation end products therapies as novel treatment for abdominal aortic aneurysm Ann Surg 250 2009 416 423
34. A. Bierhaus, S. Chevion, M. Chevion Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells Diabetes 46 1997 1481 1490 (Pubitemid 27369087)
35. H. Kim, H.J. Kim, K. Lee Alpha-lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway J Cell Mol Med 16 2012 273 286
36. M. Liao, Z. Liu, J. Bao A proteomic study of the aortic media in human thoracic aortic dissection: implication for oxidative stress J Thorac Cardiovasc Surg 136 2008 65 72 72e13