-
2
-
-
67650807295
-
Sitespecific molecular signatures predict aggressive disease in HNSCC
-
Belbin TJ, Schlecht NF, Smith RV, Adrien LR, Kawachi N, Brandwein-Gensler M, Bergman A, Chen Q, Childs G, Prystowsky MB: Sitespecific molecular signatures predict aggressive disease in HNSCC. Head Neck Pathol 2008; 2: 243-256.
-
(2008)
Head Neck Pathol
, vol.2
, pp. 243-256
-
-
Belbin, T.J.1
Schlecht, N.F.2
Smith, R.V.3
Adrien, L.R.4
Kawachi, N.5
Brandwein-Gensler, M.6
Bergman, A.7
Chen, Q.8
Childs, G.9
Prystowsky, M.B.10
-
3
-
-
77956980116
-
Tobacco and alcohol use increases the risk of both HPV-associated and HPV-independent head and neck cancers
-
Smith EM, Rubenstein LM, Haugen TH, Hamsikova E, Turek LP: Tobacco and alcohol use increases the risk of both HPV-associated and HPV-independent head and neck cancers. Cancer Causes Control 2010; 21: 1369-1378.
-
(2010)
Cancer Causes Control
, vol.21
, pp. 1369-1378
-
-
Smith, E.M.1
Rubenstein, L.M.2
Haugen, T.H.3
Hamsikova, E.4
Turek, L.P.5
-
4
-
-
67349186933
-
Global epidemiology of oral and oropharyngeal cancer
-
Warnakulasuriya S: Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009; 45: 309-316.
-
(2009)
Oral Oncol
, vol.45
, pp. 309-316
-
-
Warnakulasuriya, S.1
-
5
-
-
77954190940
-
Human papillomavirus and survival of patients with oropharyngeal cancer
-
Ang KK, Harris J, Wheeler R, Weber R, Rosenthal DI, Nguyen-Tan PF, Westra WH, Chung CH, Jordan RC, Lu C, et al: Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 2010; 363: 24-35.
-
(2010)
N Engl J Med
, vol.363
, pp. 24-35
-
-
Ang, K.K.1
Harris, J.2
Wheeler, R.3
Weber, R.4
Rosenthal, D.I.5
Nguyen-Tan, P.F.6
Westra, W.H.7
Chung, C.H.8
Jordan, R.C.9
Lu, C.10
-
6
-
-
39649109915
-
Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial
-
Fakhry C, Westra WH, Li S, Cmelak A, Ridge JA, Pinto H, Forastiere A, Gillison ML: Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 2008; 100: 261-269.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 261-269
-
-
Fakhry, C.1
Westra, W.H.2
Li, S.3
Cmelak, A.4
Ridge, J.A.5
Pinto, H.6
Forastiere, A.7
Gillison, M.L.8
-
7
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt MS, Bennett WP, Hollstein M, Harris CC: Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res 1994; 54: 4855-4878.
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
8
-
-
0029972806
-
P53: Puzzle and paradigm
-
Ko LJ, Prives C: p53: puzzle and paradigm. Genes Dev 1996; 10: 1054-1072.
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
9
-
-
0042692855
-
Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity
-
Resnick MA, Inga A: Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity. Proc Natl Acad Sci U S A 2003; 100: 9934-9939.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 9934-9939
-
-
Resnick, M.A.1
Inga, A.2
-
10
-
-
84862636275
-
Mutant p53: One name, many proteins
-
Freed-Pastor WA, Prives C: Mutant p53: one name, many proteins. Genes Dev 2012; 26: 1268-1286.
-
(2012)
Genes Dev
, vol.26
, pp. 1268-1286
-
-
Freed-Pastor, W.A.1
Prives, C.2
-
11
-
-
10944236962
-
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
-
Olive KP, Tuveson DA, Ruhe ZC, Yin B, Willis NA, Bronson RT, Crowley D, Jacks T: Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell 2004; 119: 847-860.
-
(2004)
Cell
, vol.119
, pp. 847-860
-
-
Olive, K.P.1
Tuveson, D.A.2
Ruhe, Z.C.3
Yin, B.4
Willis, N.A.5
Bronson, R.T.6
Crowley, D.7
Jacks, T.8
-
12
-
-
70349443284
-
When mutants gain new powers: News from the mutant p53 field
-
Brosh R, Rotter V: When mutants gain new powers: News from the mutant p53 field. Nat Rev Cancer 2009; 9: 701-713.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 701-713
-
-
Brosh, R.1
Rotter, V.2
-
13
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA: Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
14
-
-
80052158097
-
The mutational landscape of head and neck squamous cell carcinoma
-
Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, Kryukov GV, Lawrence MS, Sougnez C, McKenna A, et al: The mutational landscape of head and neck squamous cell carcinoma. Science 2011; 333: 1157-1160.
-
(2011)
Science
, vol.333
, pp. 1157-1160
-
-
Stransky, N.1
Egloff, A.M.2
Tward, A.D.3
Kostic, A.D.4
Cibulskis, K.5
Sivachenko, A.6
Kryukov, G.V.7
Lawrence, M.S.8
Sougnez, C.9
McKenna, A.10
-
15
-
-
72549102589
-
Human papillomavirus in head and neck cancer: Its role in pathogenesis and clinical implications
-
Chung CH, Gillison ML: Human papillomavirus in head and neck cancer: its role in pathogenesis and clinical implications. Clin Cancer Res 2009; 15: 6758-6762.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6758-6762
-
-
Chung, C.H.1
Gillison, M.L.2
-
16
-
-
84891916240
-
Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins (review)
-
Ruttkay-Nedecky B, Jimenez Jimenez AM, Nejdl L, Chudobova D, Gumulec J, Masarik M, Adam V, Kizek R: Relevance of infection with human papillomavirus: the role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins (review). Int J Oncol 2013; 43: 1754-1762.
-
(2013)
Int J Oncol
, vol.43
, pp. 1754-1762
-
-
Ruttkay-Nedecky, B.1
Jimenez Jimenez, A.M.2
Nejdl, L.3
Chudobova, D.4
Gumulec, J.5
Masarik, M.6
Adam, V.7
Kizek, R.8
-
17
-
-
84881424926
-
Enhanced radiation sensitivity in HPV-positive head and neck cancer
-
Kimple RJ, Smith MA, Blitzer GC, Torres AD, Martin JA, Yang RZ, Peet CR, Lorenz LD, Nickel KP, Klingelhutz AJ, et al: Enhanced radiation sensitivity in HPV-positive head and neck cancer. Cancer Res 2013; 73: 4791-4800.
-
(2013)
Cancer Res
, vol.73
, pp. 4791-4800
-
-
Kimple, R.J.1
Smith, M.A.2
Blitzer, G.C.3
Torres, A.D.4
Martin, J.A.5
Yang, R.Z.6
Peet, C.R.7
Lorenz, L.D.8
Nickel, K.P.9
Klingelhutz, A.J.10
-
18
-
-
0028960673
-
Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck
-
Brennan JA, Boyle JO, Koch WM, Goodman SN, Hruban RH, Eby YJ, Couch MJ, Forastiere AA, Sidransky D: Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. N Engl J Med 1995; 332: 712-717.
-
(1995)
N Engl J Med
, vol.332
, pp. 712-717
-
-
Brennan, J.A.1
Boyle, J.O.2
Koch, W.M.3
Goodman, S.N.4
Hruban, R.H.5
Eby, Y.J.6
Couch, M.J.7
Forastiere, A.A.8
Sidransky, D.9
-
19
-
-
0026468373
-
Frequent p53 mutations in head and neck cancer
-
Somers KD, Merrick MA, Lopez ME, Incognito LS, Schechter GL, Casey G: Frequent p53 mutations in head and neck cancer. Cancer Res 1992; 52: 5997-6000.
-
(1992)
Cancer Res
, vol.52
, pp. 5997-6000
-
-
Somers, K.D.1
Merrick, M.A.2
Lopez, M.E.3
Incognito, L.S.4
Schechter, G.L.5
Casey, G.6
-
20
-
-
0029996069
-
Clinical implications of the p53 gene
-
Sidransky D, Hollstein M: Clinical implications of the p53 gene. Annu Rev Med 1996; 47: 285-301.
-
(1996)
Annu Rev Med
, vol.47
, pp. 285-301
-
-
Sidransky, D.1
Hollstein, M.2
-
21
-
-
0031971038
-
TP53 genetic alterations in head-and-neck carcinomas from Brazil
-
Nagai MA, Miracca EC, Yamamoto L, Moura RP, Simpson AJ, Kowalski LP, Brentani RR: TP53 genetic alterations in head-and-neck carcinomas from Brazil. Int J Cancer 1998; 76: 13-18.
-
(1998)
Int J Cancer
, vol.76
, pp. 13-18
-
-
Nagai, M.A.1
Miracca, E.C.2
Yamamoto, L.3
Moura, R.P.4
Simpson, A.J.5
Kowalski, L.P.6
Brentani, R.R.7
-
22
-
-
0037151917
-
No consent should be needed for using leftover body material for scientific purposes. for
-
van Diest PJ: No consent should be needed for using leftover body material for scientific purposes. For. BMJ 2002; 325: 648-651.
-
(2002)
BMJ
, vol.325
, pp. 648-651
-
-
Van Diest, P.J.1
-
24
-
-
0032407336
-
Differences in expression of oncogenes and tumor suppressor genes in different sites of head and neck squamous cell
-
Takes RP, Baatenburg de Jong RJ, Schuuring E, Litvinov SV, Hermans J, Van Krieken JH: Differences in expression of oncogenes and tumor suppressor genes in different sites of head and neck squamous cell. Anticancer Res 1998; 18: 4793-4800.
-
(1998)
Anticancer Res
, vol.18
, pp. 4793-4800
-
-
Takes, R.P.1
Baatenburg De Jong, R.J.2
Schuuring, E.3
Litvinov, S.V.4
Hermans, J.5
Van Krieken, J.H.6
-
25
-
-
84892619242
-
Differences in methylation profiles between HPVpositive and HPV-negative oropharynx squamous cell carcinoma: A systematic review
-
van Kempen PM, Noorlag R, Braunius WW, Stegeman I, Willems SM, Grolman W: Differences in methylation profiles between HPVpositive and HPV-negative oropharynx squamous cell carcinoma: A systematic review. Epigenetics 2014; 9: 194-203.
-
(2014)
Epigenetics
, vol.9
, pp. 194-203
-
-
Van Kempen, P.M.1
Noorlag, R.2
Braunius, W.W.3
Stegeman, I.4
Willems, S.M.5
Grolman, W.6
-
26
-
-
84886433630
-
Unique DNA methylation loci distinguish anatomic site and HPV status in head and neck squamous cell carcinoma
-
Lleras RA, Smith RV, Adrien LR, Schlecht NF, Burk RD, Harris TM, Childs G, Prystowsky MB, Belbin TJ: Unique DNA methylation loci distinguish anatomic site and HPV status in head and neck squamous cell carcinoma. Clin Cancer Res 2013; 19: 5444-5455.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 5444-5455
-
-
Lleras, R.A.1
Smith, R.V.2
Adrien, L.R.3
Schlecht, N.F.4
Burk, R.D.5
Harris, T.M.6
Childs, G.7
Prystowsky, M.B.8
Belbin, T.J.9
-
27
-
-
0030484547
-
P53 mutations associated with breast, colorectal, liver, lung, and ovarian cancers
-
Lasky T, Silbergeld E: P53 mutations associated with breast, colorectal, liver, lung, and ovarian cancers. Environ Health Perspect 1996; 104: 1324-1331.
-
(1996)
Environ Health Perspect
, vol.104
, pp. 1324-1331
-
-
Lasky, T.1
Silbergeld, E.2
-
28
-
-
37349055876
-
TP53 mutations and survival in squamous-cell carcinoma of the head and neck
-
Poeta ML, Manola J, Goldwasser MA, Forastiere A, Benoit N, Califano JA, Ridge JA, Goodwin J, Kenady D, Saunders J, et al: TP53 mutations and survival in squamous-cell carcinoma of the head and neck. N Engl J Med 2007; 357: 2552-2561.
-
(2007)
N Engl J Med
, vol.357
, pp. 2552-2561
-
-
Poeta, M.L.1
Manola, J.2
Goldwasser, M.A.3
Forastiere, A.4
Benoit, N.5
Califano, J.A.6
Ridge, J.A.7
Goodwin, J.8
Kenady, D.9
Saunders, J.10
-
29
-
-
0034801362
-
Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese
-
Hsieh LL, Wang PF, Chen IH, Liao CT, Wang HM, Chen MC, Chang JT, Cheng AJ: Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese. Carcinogenesis 2001; 22: 1497-1503.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1497-1503
-
-
Hsieh, L.L.1
Wang, P.F.2
Chen, I.H.3
Liao, C.T.4
Wang, H.M.5
Chen, M.C.6
Chang, J.T.7
Cheng, A.J.8
-
30
-
-
0029900625
-
P53 gene mutations in oral carcinomas from India
-
Munirajan AK, Tutsumi-Ishii Y, Mohanprasad BK, Hirano Y, Munakata N, Shanmugam G, Tsuchida N: p53 gene mutations in oral carcinomas from India. Int J Cancer 1996; 66: 297-300.
-
(1996)
Int J Cancer
, vol.66
, pp. 297-300
-
-
Munirajan, A.K.1
Tutsumi-Ishii, Y.2
Mohanprasad, B.K.3
Hirano, Y.4
Munakata, N.5
Shanmugam, G.6
Tsuchida, N.7
-
31
-
-
0035890360
-
Increased p53 mutation frequency during tumor progression-results from a breast cancer cohort
-
Norberg T, Klaar S, Karf G, Nordgren H, Holmberg L, Bergh J: Increased p53 mutation frequency during tumor progression-results from a breast cancer cohort. Cancer Res 2001; 61: 8317-8321.
-
(2001)
Cancer Res
, vol.61
, pp. 8317-8321
-
-
Norberg, T.1
Klaar, S.2
Karf, G.3
Nordgren, H.4
Holmberg, L.5
Bergh, J.6
-
32
-
-
0032833964
-
Head and neck cancer in nonsmokers: A distinct clinical and molecular entity
-
Koch WM, Lango M, Sewell D, Zahurak M, Sidransky D: Head and neck cancer in nonsmokers: A distinct clinical and molecular entity. Laryngoscope 1999; 109: 1544-1551.
-
(1999)
Laryngoscope
, vol.109
, pp. 1544-1551
-
-
Koch, W.M.1
Lango, M.2
Sewell, D.3
Zahurak, M.4
Sidransky, D.5
-
33
-
-
0027415517
-
Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract
-
Chung KY, Mukhopadhyay T, Kim J, Casson A, Ro JY, Goepfert H, Hong WK, Roth JA: Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract. Cancer Res 1993; 53: 1676-1683.
-
(1993)
Cancer Res
, vol.53
, pp. 1676-1683
-
-
Chung, K.Y.1
Mukhopadhyay, T.2
Kim, J.3
Casson, A.4
Ro, J.Y.5
Goepfert, H.6
Hong, W.K.7
Roth, J.A.8
-
34
-
-
0032922061
-
Sequencing analysis of RNA and DNA of exons 1 through 11 shows p53 gene alterations to be present in almost 100% of head and neck squamous cell cancers
-
Kropveld A, Rozemuller EH, Leppers FG, Scheidel KC, de Weger RA, Koole R, Hordijk GJ, Slootweg PJ, Tilanus MG: Sequencing analysis of RNA and DNA of exons 1 through 11 shows p53 gene alterations to be present in almost 100% of head and neck squamous cell cancers. Lab Invest 1999; 79: 347-353.
-
(1999)
Lab Invest
, vol.79
, pp. 347-353
-
-
Kropveld, A.1
Rozemuller, E.H.2
Leppers, F.G.3
Scheidel, K.C.4
De Weger, R.A.5
Koole, R.6
Hordijk, G.J.7
Slootweg, P.J.8
Tilanus, M.G.9
-
35
-
-
0035992224
-
A new marker determining clonal outgrowth
-
Mao L: A new marker determining clonal outgrowth. Clin Cancer Res 2002; 8: 2021-2023.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2021-2023
-
-
Mao, L.1
-
36
-
-
43949101000
-
Use of trastuzumab in the therapy of breast cancer
-
Riemer AB, Zielinski CC: Use of trastuzumab in the therapy of breast cancer. Ther Umsch 2008; 65: 217-222.
-
(2008)
Ther Umsch
, vol.65
, pp. 217-222
-
-
Riemer, A.B.1
Zielinski, C.C.2
-
37
-
-
84861495556
-
Therapeutic targeting of the epidermal growth factor receptor in human cancer
-
Dhomen NS, Mariadason J, Tebbutt N, Scott AM: Therapeutic targeting of the epidermal growth factor receptor in human cancer. Crit Rev Oncog 2012; 17: 31-50.
-
(2012)
Crit Rev Oncog
, vol.17
, pp. 31-50
-
-
Dhomen, N.S.1
Mariadason, J.2
Tebbutt, N.3
Scott, A.M.4
-
38
-
-
75149134332
-
Toward the rational design of p53-stabilizing drugs: Probing the surface of the oncogenic Y220C mutant
-
Basse N, Kaar JL, Settanni G, Joerger AC, Rutherford TJ, Fersht AR: Toward the rational design of p53-stabilizing drugs: probing the surface of the oncogenic Y220C mutant. Chem Biol 2010; 17: 46-56.
-
(2010)
Chem Biol
, vol.17
, pp. 46-56
-
-
Basse, N.1
Kaar, J.L.2
Settanni, G.3
Joerger, A.C.4
Rutherford, T.J.5
Fersht, A.R.6
|