p53 mutations associated with breast, colorectal, liver, lung, and ovarian cancers

Environmental Health Perspectives

Volumn 104, Issue 12, 1996, Pages 1324-1331

  Lasky, Tamar ^a   Silbergeld, Ellen ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

Amino acid; Cancer; Database; Epidemiology; Gene; Molecular epidemiology; Mutation; p53

Indexed keywords

AMINO ACID; ARGININE; CYSTEINE; GENE PRODUCT; HISTIDINE;

AMINO ACID SUBSTITUTION; ARTICLE; BASE PAIRING; BREAST CANCER; COLORECTAL CANCER; COMPARATIVE STUDY; DATA BASE; GENE MUTATION; HUMAN; LIVER CANCER; LUNG CANCER; OVARY CANCER; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TUMOR SUPPRESSOR GENE;

EID: 0030484547     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.961041324     Document Type: Article

References (36)

1. Harris CC, Hollstein M. Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 329:1318-1327 (1993).
2. Selivanova G, Wiman KG. p53: a cell cycle regulator activated by DNA damage. Adv Cancer Res 66:143-148 (1995).
3. Hollstein M, Sidransky D, Harris CC. p53 mutations in human cancer. Science 253:49-53 (1991).
4. Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878 (1994).
5. Bogler O, Huang HJ, Kleihues P, Cavenee WK. The p53 gene and its role in human brain tumors. Glia 15:308-327 (1995).
6. Kastan MB, Canman CE, Leonard CJ. p53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev 14:3-15 (1995).
7. Lee JM, Bernstein A. Apoptosis, cancer and the p53 tumour suppressor gene. Cancer Metastasis Rev 14:149-161 (1995).
8. Gotz C, Montenarh M. p53: DNA damage, DNA repair, and apoptosis. Rev Physiol Biochem Pharmacol 127:65-95 (1996).
9. Ozbun MA, Butel JS. Tumor suppressor p53 mutations and breast cancer: a critical analysis. Adv Cancer Res 66:71-141 (1995).
10. Harris CC. The 1995 Walter Hubert Lecture - molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene. Br J Cancer 73:261-269 (1996.)
11. Harris CC. 1995 Deichmann Lecture-p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology and cancer risk assessment. Toxicol Lett 82-83:1-7 (1995).
12. Harris CC. p53: At the crossroads of molecular carcinogenesis and risk assessment. Science 262:1980-1981 (1993).
13. 1 induces the transversion of G to T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc Natl Acad Sci USA 90:8586-8590 (1993).
14. Hollstein M, Marion MJ, Lehman T, Welsh J, Harris CC, Martel-Planche G, Kusters I, Montesano R. p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers. Carcinogenesis 15:1-3 (1994).
15. Takeshima Y, Inai K, Bennett WP, Metcalf RA, Welsh JA, Yonehara S, Hayashi Y, Fujihara M, Yamakido M, Akiyama M. p53 mutations in lung cancers from Japanese mustard gas workers. Carcinogenesis 15:2075-2079 (1994).
16. Basset-Seguin N, Moles JP, Mils V, Dereure O, Guilhou JJ. TP53 tumor suppressor gene and skin Carcinogenesis. J Invest Dermatol 103:102S-106S (1994).
17. Nakazawa H, English D, Randell PL, Nakazawa K, Martel N, Armstrong BK, Yamasaki H. UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement. Proc Natl Acad Sci USA 91:360-364(1994).
18. Taguchi M, Watanabe S, Yashima K, Murakami Y, Sekiya T, lkeda S. Aberrations of the tumor suppressor p53 gene and p53 protein in solar keratosis in human skin. J Invest Dermatol 103:500-533 (1994).
19. Daya-Grosjean L, Dumaz N, Sarasin A. The specificity of p53 mutation spectra in sunlight induced human cancers. J Photochem Photobiol B 28:115-24 (1995).
20. Hussain SP, Aguilar F, Cerutti P. Mutagenesis of codon 248 of the human p53 tumor suppressor gene by N-ethyl-N-nitrosourea. Oncogene 9:13-18 (1994).
21. Esteve A, Sorlie T, Martel-Planche G, Hollstein M, Kusters I, Lewalter J, Vineis P, StephanOdenthal M, Montesano R. Screening for p53 gene mutations in archived tumors of workers occupationally exposed to carcinogens: examples from analysis of bladder tumors. J Occup Environ Med 37:59-68 (1995).
22. Vogelstein B, Kinzler KW. Carcinogens leave fingerprints. Nature 355:209-210 (1992).
23. Biggs PJ, Warren W, Venitt S, Stratton MR. Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer. Mutagenesis 8:275-283 (1993).
24. Chang F, Syrjanen S, Tervahauta A, Kurvinen K, Wang L, Syrjanen K. Frequent mutations of p53 gene in oesophageal squamous cell carcinomas with and without human papillomavirus (HPV) involvement suggest the dominant role of environmental carcinogens in oesophageal Carcinogenesis. Br J Cancer 70:346-351 (1994).
25. Hartmann A, Rosanelli G, Blaszyk H, Cunningham JM, McGovern RM, Schroeder JJ, Schaid DJ, Kovach JS, Sommer SS. Novel pattern of p53 mutation in breast cancers from Austrian women. J Clin Invest 95:686-689 (1995).
26. Watanabe M, Ushijima T, Kakiuchi H, Shiraishi T, Yatani R, Shimazaki J, Kotake T, Sugimura T, Nagao M. p53 gene mutations in human prostate cancers in Japan: different mutation spectra between Japan and Western countries. Jpn J Cancer Res 85:904-910 (1994).
27. Redston MS, Caldas C, Seymour AB, Hruban RH, da Costa L, Yeo CJ, Kern SE. p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res 54:3025-3033 (1994).
28. Chi SG, deVere-White RW, Meyers FJ, Siders DB, Lee F, Gumerlock PH. p53 in prostate cancer: frequent expressed transition mutations. J Natl Cancer Inst 86:926-933 (1994).
29. Levine AJ, Wu MC, Chang A, Silver A, Attiyeh EF, Lin J, Epstein CB. The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype. Ann NY Acad Sci 768:111-128 (1995).
30. Shibata A, Ohneseit PF, Tsai YC, Spruck CR, Nichols PW, Chiang HS, Lai MK, Jones PA. Mutational spectrum in the p53 gene in bladder tumors from the endemic area of black foot disease in Taiwan. Carcinogenesis 15:1085-1087 (1994).
31. Cariello NF, Cui L, Beroud C, Soussi T. Database and software for the analysis of mutations in the human p53 gene. Cancer Res 54:4454-4460 (1994).
32. Hollstein M, Rice K, Greenblatt MS, Soussi T, Fuchs R, Sorlie T, Hovig E, Smith-Sorensen B, Montesano R, Harris CC. Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res 22:3551-3555 (1994).
33. Cariello NF, Piegorsch WW, Adams WT, Skopek TR. Computer program for the analysis of mutational spectra: application to p53 mutations. Carcinogenesis 15:2281-2285 (1994).
34. Hennekens CH, Buring JE. Epidemiology in medicine. Boston:Little, Brown and Company, 1987.
35. Denissenko MF, Pao A, Tang M, Pfeifer GP. Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in p53. Science 274:430-432 (1996)
36. Hartmann A, Blaszyk H, McGovern RM, Schroeder JJ, Cunningham J, De Vries EM, Kovach JS, Sommer SS. p53 gene mutations inside and outside of exons 5-8: the patterns differ in breast and other cancers. Oncogene 10:681-688 (1995).