Engineering lipid overproduction in the oleaginous yeast Yarrowia lipolytica

Metabolic Engineering

Volumn 29, Issue , 2015, Pages 56-65

  Qiao, Kangjian ^a   Imam Abidi, Syed Hussain ^a,c   Liu, Hongjuan ^a,d   Zhang, Haoran ^a   Chakraborty, Sagar ^a   Watson, Nicki ^b   Kumaran Ajikumar, Parayil ^a,e   Stephanopoulos, Gregory ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c Butazyme Incorporation   (United States)

^d TSINGHUA UNIVERSITY   (China)

^e Manus Biosynthesis   (United States)

Author keywords

Autophagy; Biodiesel; Metabolic engineering; Triacylglycerol

Indexed keywords

BIODIESEL; CELL DEATH; CELL PROLIFERATION; COST EFFECTIVENESS; MAMMALS; METABOLISM; PRODUCTIVITY; REVERSE ENGINEERING; SATURATED FATTY ACIDS; SUGARS; YEAST;

ACETYL-COA CARBOXYLASE; ALLOSTERIC INHIBITION; AUTOPHAGY; BIODIESEL PRODUCTION; COST-EFFECTIVE PRODUCTION; LIPID PRODUCTIVITIES; STEAROYL-COA DESATURASE; TRIACYLGLYCEROLS;

METABOLIC ENGINEERING;

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; ACYL COENZYME A DESATURASE 9 DELTA; BIODIESEL; CELLULOSE; DIACYLGLYCEROL ACYLTRANSFERASE; GLUCOSE; GLYCEROL; MONOUNSATURATED FATTY ACID; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID; DELTA-9 FATTY ACID DESATURASE; FUNGAL PROTEIN; LIPID;

ARTICLE; AUTOPHAGY; BIOMASS PRODUCTION; CATALYST; CELL GROWTH; COST EFFECTIVENESS ANALYSIS; CYTOSKELETON; ELECTRON MICROSCOPY; FED BATCH FERMENTATION; FLUORESCENCE MICROSCOPY; LIMIT OF QUANTITATION; LIPID STORAGE; LIPOGENESIS; METABOLIC ENGINEERING; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PRODUCTIVITY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE ENGINEERING; RNA ISOLATION; SERIAL ANALYSIS OF GENE EXPRESSION; TRANSMISSION ELECTRON MICROSCOPY; WILD TYPE; YARROWIA LIPOLYTICA; BIOSYNTHESIS; GENETICS; METABOLISM; YARROWIA;

MAMMALIA; YARROWIA LIPOLYTICA;

ACETYL-COA CARBOXYLASE; DIACYLGLYCEROL O-ACYLTRANSFERASE; FATTY ACID DESATURASES; FUNGAL PROTEINS; LIPIDS; METABOLIC ENGINEERING; YARROWIA;

EID: 84924657793     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.02.005     Document Type: Article

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