Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease

Frontiers in Aging Neuroscience

Volumn 7, Issue FEB, 2015, Pages

  Silva Albequerque, Marilia ^a,b,c   Mahar, Ian ^a,d   Davoli, Maria Antonietta ^a   Chabot, Jean Guy ^a,d   Mechawar, Naguib ^a,d   Quirion, Rémi ^a,d   Krantic, Slavica ^a,d,e  

^a DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c Research Group on Neuropharmacology of Aging   (Brazil)

^d MCGILL UNIVERSITY   (Canada)

^e SORBONNE UNIVERSITÉ   (France)

Author keywords

Alzheimer's disease; Hippocampal sub regions; Neuropeptide Y; Parvalbumin; Somatostatin

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALBUMIN; MOLECULAR LAYER; NEUROPEPTIDE Y; PARAVALBUMIN; SOMATOSTATIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; EXPERIMENTAL MODEL; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL; NERVE CELL EXCITABILITY; NERVE CELL NETWORK; NONHUMAN; PROTEIN EXPRESSION; STRATUM ORIENS; STRATUM PYRAMIDALE; STRATUM RADIATUM;

EID: 84924609104     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2015.00030     Document Type: Article

References (33)

1. Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356.
2. Hardy J (2006) A hundred years of Alzheimer's disease research. Neuron 52, 3-13.
3. Nelson AP, O'Connor MG (2008) Mild cognitive impairment: a neuropsychological perspective. CNS Spectr 13, 56-64.
4. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
5. Ramos B, Baglietto-Vargas D, del Rio JC, Moreno-Gonzalez I, Santa-Maria C, Jimenez S, Caballero C, Lopez-Tellez JF, Khan ZU, Ruano D, Gutierrez A, Vitorica J (2006) Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1xAPP transgenic model of Alzheimer's disease. Neurobiol Aging 27, 1658-1672.
6. Krantic S, Isorce N, Mechawar N, Davoli MA, Vignault E, Albuquerque M, Chabot JG, Moyse E, Chauvin JP, Aubert I, McLaurin J, Quirion R (2012) Hippocampal GABAergic neurons are susceptible to amyloid-beta toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model. J Alzheimers Dis 29, 293-308.
7. Jolas T, Zhang XS, Zhang Q, Wong G, Del Vecchio R, Gold L, Priestley T (2002) Long-term potentiation is increased in the CA1 area of the hippocampus of APP(swe/ind) CRND8 mice. Neurobiol Dis 11, 394-409.
8. Del Vecchio RA, Gold LH, Novick SJ, Wong G, Hyde LA (2004) Increased seizure threshold and severity in young transgenic CRND8 mice. Neurosci Lett 367, 164-167.
9. Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L (2007) Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron 55, 697-711.
10. Gleichmann M, Chow VW, Mattson MP (2011) Homeostatic disinhibition in the aging brain and Alzheimer's disease. J Alzheimers Dis 24, 15-24.
11. Palop JJ, Mucke L (2009) Epilepsy and cognitive impairments in Alzheimer disease. Arch Neurol 66, 435-440.
12. Verret L, Mann EO, Hang GB, Barth AM, Cobos I, Ho K, Devidze N, Masliah E, Kreitzer AC, Mody I, Mucke L, Palop JJ (2012) Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell 149, 708- 721.
13. Maccaferri G, Lacaille JC (2003) Interneuron Diversity series: Hippocampal interneuron classifications--making things as simple as possible, not simpler. Trends Neurosci 26, 564-571.
14. Klausberger T, Magill PJ, Marton LF, Roberts JD, Cobden PM, Buzsaki G, Somogyi P (2003) Brain-state- and cell-type-specific firing of hippocampal interneurons in vivo. Nature 421, 844-848.
15. Klausberger T, Marton LF, Baude A, Roberts JD, Magill PJ, Somogyi P (2004) Spike timing of dendrite-targeting bistratified cells during hippocampal network oscillations in vivo. Nat Neurosci 7, 41-47.
16. Goutagny R, Jackson J, Williams S (2009) Self-generated theta oscillations in the hippocampus. Nat Neurosci 12, 1491-1493.
17. Jackson J, Amilhon B, Goutagny R, Bott JB, Manseau F, Kortleven C, Bressler SL, Williams S (2014) Reversal of theta rhythm flow through intact hippocampal circuits. Nat Neurosci 17, 1362-1370.
18. Chishti MA, Yang DS, Janus C, Phinney AL, Horne P, Pearson J, Strome R, Zuker N, Loukides J, French J, Turner S, Lozza G, Grilli M, Kunicki S, Morissette C, Paquette J, Gervais F, Bergeron C, Fraser PE, Carlson GA, George-Hyslop PS, Westaway D (2001) Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 276, 21562-21570.
19. Franklin KBJ, Paxinos G (2007) The Mouse Brain in Stereotaxic coordinates., Academic Press, San Diego.
20. Saiz-Sanchez D, De La Rosa-Prieto C, Ubeda-Banon I, Martinez-Marcos A (2013) Interneurons and beta-amyloid in the olfactory bulb, anterior olfactory nucleus and olfactory tubercle in APPxPS1 transgenic mice model of Alzheimer's disease. Anat Rec (Hoboken) 296, 1413-1423.
21. Saiz-Sanchez D, Ubeda-Banon I, De la Rosa-Prieto C, Martinez-Marcos A (2012) Differential expression of interneuron populations and correlation with amyloid-beta deposition in the olfactory cortex of an AbetaPP/PS1 transgenic mouse model of Alzheimer's disease. J Alzheimers Dis 31, 113-129.
22. Lemmens MA, Sierksma AS, Rutten BP, Dennissen F, Steinbusch HW, Lucassen PJ, Schmitz C (2011) Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer's disease. Brain Struct Funct 216, 227-237.
23. Saiz-Sanchez D, De la Rosa-Prieto C, Ubeda-Banon I, Martinez-Marcos A (2014) Interneurons, tau and amyloid-beta in the piriform cortex in Alzheimer's disease. Brain Struct Funct.
24. Freund TF, Buzsaki G (1996) Interneurons of the hippocampus. Hippocampus 6, 347- 470.
25. Goutagny R, Gu N, Cavanagh C, Jackson J, Chabot JG, Quirion R, Krantic S, Williams S (2013) Alterations in hippocampal network oscillations and theta-gamma coupling arise before Abeta overproduction in a mouse model of Alzheimer's disease. Eur J Neurosci 37, 1896-1902.
26. Takahashi H, Brasnjevic I, Rutten BP, Van Der Kolk N, Perl DP, Bouras C, Steinbusch HW, Schmitz C, Hof PR, Dickstein DL (2010) Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer's disease. Brain Struct Funct 214, 145-160.
27. Stanley EM, Fadel JR, Mott DD (2012) Interneuron loss reduces dendritic inhibition and GABA release in hippocampus of aged rats. Neurobiol Aging 33, 431 e431-413.
28. Zhang MY, Zheng CY, Zou MM, Zhu JW, Zhang Y, Wang J, Liu CF, Li QF, Xiao ZC, Li S, Ma QH, Xu RX (2014) Lamotrigine attenuates deficits in synaptic plasticity and accumulation of amyloid plaques in APP/PS1 transgenic mice. Neurobiol Aging 35, 2713-2725.
29. Shi JQ, Zhang CC, Sun XL, Cheng XX, Wang JB, Zhang YD, Xu J, Zou HQ (2013) Antimalarial drug artemisinin extenuates amyloidogenesis and neuroinflammation in APPswe/PS1dE9 transgenic mice via inhibition of nuclear factor-kappaB and NLRP3 inflammasome activation. CNS Neurosci Ther 19, 262-268.
30. Devi L, Ohno M (2013) Effects of levetiracetam, an antiepileptic drug, on memory impairments associated with aging and Alzheimer's disease in mice. Neurobiol Learn Mem 102, 7-11.
31. Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu GQ, Palop JJ, Mucke L (2012) Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model. Proc Natl Acad Sci U S A 109, E2895-2903.
32. Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind MD, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L (2013) Seizures and epileptiform activity in the early stages of Alzheimer disease. JAMA Neurol 70, 1158-1166.
33. Bakker A, Krauss GL, Albert MS, Speck CL, Jones LR, Stark CE, Yassa MA, Bassett SS, Shelton AL, Gallagher M (2012) Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron 74, 467-474.