Strong hypoxia reduces leptin synthesis in purified primary human trophoblasts

Placenta

Volumn 36, Issue 4, 2015, Pages 427-432

  Nusken E ^a   Herrmann, Y ^b   Wohlfarth, M ^a   Goecke, T W ^b,c   Appel, S ^a   Schneider, H ^b   Dotsch J ^a,b   Nusken K D ^a,b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Hypoxia; Leptin leptin receptor; Placenta; Trophoblast

Indexed keywords

CASPASE 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN RECEPTOR; LEPTIN; LEPTIN RECEPTOR; OXYGEN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; VASCULOTROPIN A; HIF1A PROTEIN, HUMAN; INSR PROTEIN, HUMAN; LEPTIN RECEPTOR, HUMAN; LEUKOCYTE ANTIGEN; MESSENGER RNA;

APOPTOSIS; ARTICLE; FEMALE; GENE EXPRESSION; HORMONE SYNTHESIS; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYPOXIA; OXYGEN CONCENTRATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; TROPHOBLAST; UPREGULATION; ADULT; CELL CULTURE; CELL HYPOXIA; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PLACENTA; PREGNANCY; PROTEIN STABILITY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THIRD TRIMESTER PREGNANCY; WESTERN BLOTTING;

ADULT; ANTIGENS, CD; APOPTOSIS; BLOTTING, WESTERN; CELL HYPOXIA; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LEPTIN; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, THIRD; PROTEIN STABILITY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, INSULIN; RECEPTORS, LEPTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TROPHOBLASTS;

EID: 84924595551     PISSN: 01434004     EISSN: 15323102     Source Type: Journal    
DOI: 10.1016/j.placenta.2015.01.191     Document Type: Article

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