Review: Leptin gene expression in the placenta - Regulation of a key hormone in trophoblast proliferation and survival

Placenta

Volumn 32, Issue SUPPL. 2, 2011, Pages

  Maymo J L ^a   Perez Perez A ^b   Gambino, Y ^a   Calvo, J C ^a,c   Sanchez Margalet V ^b   Varone, C L ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

^c INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

Author keywords

Gene expression; Leptin; Placenta; Signal transduction pathways

Indexed keywords

CHORIONIC GONADOTROPIN; CYCLIC AMP; ESTRADIOL; JANUS KINASE; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; STAT PROTEIN;

CELL PROLIFERATION; CELL SURVIVAL; CONFERENCE PAPER; GENE EXPRESSION; GENE FUNCTION; HUMAN; NIDATION; PLACENTA; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TROPHOBLAST; UPREGULATION;

EID: 79952004504     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2011.01.004     Document Type: Conference Paper

References (60)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-32. (Pubitemid 24365442)
2. Reitman ML, Bi S, Marcus-Samuels B, Gavrilova O. Leptin and its role in pregnancy and fetal developmentean overview. Biochem Soc Trans 2001;29:68-72. (Pubitemid 32587480)
3. Cervero A, Horcajadas JA, Dominguez F, Pellicer A, Simon C. Leptin system in embryo development and implantation: a protein in search of a function. Reprod Biomed Online 2005;10:217-23. (Pubitemid 40246637)
4. Aplin JD. The cell biological basis of human implantation. Baillieres Best Pract Res Clin Obstet Gynaecol 2000;14:757-64.
5. Achache H, Revel A. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Update 2006;12:731-46. (Pubitemid 44605511)
6. Simon C, Dominguez F, Remohi J, Pellicer A. Embryo effects in human implantation: embryonic regulation of endometrial molecules in human implantation. Ann N Y Acad Sci 2001;943:1-16. (Pubitemid 32928297)
7. Chehab FF, Qiu J, Ogus S. The use of animal models to dissect the biology of leptin. Recent Prog Horm Res 2004;59:245-66. (Pubitemid 41327154)
8. Henson MC, Castracane VD. Leptin in pregnancy: an update. Biol Reprod 2006;74:218-29. (Pubitemid 43122272)
9. Antczak M, Van Blerkom J. Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Mol Hum Reprod 1997;3:1067-86. (Pubitemid 127509913)
10. Castellucci M, De Matteis R, Meisser A, Cancello R, Monsurro V, Islami D, et al. Leptin modulates extracellular matrix molecules and metalloproteinases: possible implications for trophoblast invasion. MolHumReprod 2000;6:951-8.
11. Cameo P, Bischof P, Calvo JC. Effect of leptin on progesterone, human chorionic gonadotropin, and interleukin-6 secretion by human term trophoblast cells in culture. Biol Reprod 2003;68:472-7. (Pubitemid 36139312)
12. Magarinos MP, Sanchez-Margalet V, Kotler M, Calvo JC, Varone CL. Leptin promotes cell proliferation and survival of trophoblastic cells. Biol Reprod 2007;76:203-10. (Pubitemid 46219334)
13. Perez-Perez A, Maymo J, Duenas JL, Goberna R, Calvo JC, Varone C, et al. Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway. Arch Biochem Biophys 2008;477:390-5.
14. Baumann H, Morella KK, White DW, Dembski M, Bailon PS, Kim H, et al. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. Proc Natl Acad Sci U S A 1996;93:8374-8. (Pubitemid 26269565)
15. Ashworth CJ, Hoggard N, Thomas L, Mercer JG, Wallace JM, Lea RG. Placental leptin. Rev Reprod 2000;5:18-24. (Pubitemid 30050349)
16. Challier J, Galtier M, Bintein T, Cortez A, Lepercq J, Hauguel-de Mouzon S. Placental leptin receptor isoforms in normal and pathological pregnancies. Placenta 2003;24:92-9. (Pubitemid 37184700)
17. Corvinus FM, Fitzgerald JS, Friedrich K, Markert UR. Evidence for a correlation between trophoblast invasiveness and STAT3 activity. Am J Reprod Immunol 2003;50:316-21. (Pubitemid 37203574)
18. Martin-Romero C, Sanchez-Margalet V. Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68. Cell Immunol 2001;212:83-91. (Pubitemid 34044539)
19. Pollheimer J, Knofler M. Signalling pathways regulating the invasive differentiation of human trophoblasts: a review. Placenta 2005;26(Suppl. A):S21-30.
20. Perez-Perez A, Maymo J, Gambino Y, Duenas JL, Goberna R, Varone C, et al. Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells. Biol Reprod 2009;81:826-32.
21. Perez-Perez A, Gambino Y, Maymo J, Goberna R, Fabiani F, Varone C, et al. MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells. Biochem Biophys Res Commun 2010;396:956-60.
22. Hardie L, Trayhurn P, Abramovich D, Fowler P. Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy. Clin Endocrinol (Oxf) 1997;47:101-6. (Pubitemid 27313995)
23. Hoggard N, Haggarty P, Thomas L, Lea RG. Leptin expression in placental and fetal tissues: does leptin have a functional role? Biochem Soc Trans 2001;29:57-63.
24. Chardonnens D, Cameo P, Aubert ML, Pralong FP, Islami D, Campana A, et al. Modulation of human cytotrophoblastic leptin secretion by interleukin-1alpha and 17beta-oestradiol and its effect on HCG secretion. Mol Hum Reprod 1999;5:1077-82. (Pubitemid 29518913)
25. Ambrosini G, Nath AK, Sierra-Honigmann MR, Flores-Riveros J. Transcriptional activation of the human leptin gene in response to hypoxia. Involvement of hypoxia-inducible factor 1. J Biol Chem 2002;277:34601-9.
26. Bi S, Gavrilova O, Gong DW, Mason MM, Reitman M. Identification of a placental enhancer for the human leptin gene. J Biol Chem 1997;272:30583-8. (Pubitemid 27512274)
27. Filicori M, Fazleabas AT, Huhtaniemi I, Licht P, Rao Ch V, Tesarik J, et al. Novel concepts of human chorionic gonadotropin: reproductive system interactions and potential in the management of infertility. Fertil Steril 2005;84:275-84.
28. Islami D, Bischof P, Chardonnens D. Possible interactions between leptin, gonadotrophin-releasing hormone (GnRH-I and II) and human chorionic gonadotrophin (hCG). Eur J Obstet Gynecol Reprod Biol 2003;110:169-75. (Pubitemid 37101314)
29. Islami D, Bischof P, Chardonnens D. Modulation of placental vascular endothelial growth factor by leptin and hCG. Mol Hum Reprod 2003;9:395-8. (Pubitemid 36874297)
30. Maymo JL, Perez Perez A, Sanchez-Margalet V, Duenas JL, Calvo JC, Varone CL. Up-regulation of placental leptin by human chorionic gonadotropin. Endocrinology 2009;150:304-13.
31. Mason MM, He Y, Chen H, Quon MJ, Reitman M. Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor. Endocrinology 1998;139:1013-22.
32. Sirois J, Richards JS. Transcriptional regulation of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells. Evidence for the role of a cis-acting C/EBP beta promoter element. J Biol Chem 1993;268:21931-8. (Pubitemid 23320698)
33. Nalbant D, Williams SC, Stocco DM, Khan SA. Luteinizing hormone-dependent gene regulation in Leydig cells may be mediated by CCAAT/enhancer-binding protein-beta. Endocrinology 1998;139:272-9. (Pubitemid 28166320)
34. Dos Santos E, Dieudonne MN, Leneveu MC, Pecquery R, Serazin V, Giudicelli Y. In vitro effects of chorionic gonadotropin hormone on human adipose development. J Endocrinol 2007;194:313-25.
35. Rao CV. An overview of the past, present, and future of nongonadal LH/hCG actions in reproductive biology andmedicine.Semin ReprodMed 2001;19:7-17.
36. Menon KM, Munshi UM, Clouser CL, Nair AK. Regulation of luteinizing hormone/human chorionic gonadotropin receptor expression: a perspective. Biol Reprod 2004;70:861-6. (Pubitemid 38387694)
37. Srisuparp S, Strakova Z, Brudney A, Mukherjee S, Reierstad S, Hunzicker-Dunn M, et al. Signal transduction pathways activated by chorionic gonadotropin in the primate endometrial epithelial cells. Biol Reprod 2003;68:457-64. (Pubitemid 36139310)
38. Carvalho CR, Carvalheira JB, Lima MH, Zimmerman SF, Caperuto LC, Amanso A, et al. Novel signal transduction pathway for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and phosphoinositol 3-kinase/Akt pathways. Endocrinology 2003;144:638-47. (Pubitemid 36205238)
39. Hoeffler JP, Meyer TE, Yun Y, Jameson JL, Habener JF. Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA. Science 1988;242:1430-3. (Pubitemid 19008071)
40. Slieker LJ, Sloop KW, Surface PL, Kriauciunas A, LaQuier F, Manetta J, et al. Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP. J Biol Chem 1996;271:5301-4. (Pubitemid 26083858)
41. Szkudelski T, Nowicka E, Szkudelska K. Leptin secretion and protein kinase A activity. Physiol Res 2005;54:79-85. (Pubitemid 40363657)
42. Yura S, Sagawa N, Ogawa Y, Masuzaki H, Mise H, Matsumoto T, et al. Augmentation of leptin synthesis and secretion through activation of protein kinases A and C in cultured human trophoblastic cells. J Clin Endocrinol Metab 1998;83:3609-14. (Pubitemid 28500898)
43. Cass LA, Summers SA, Prendergast GV, Backer JM, Birnbaum MJ, Meinkoth JL. Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation. Mol Cell Biol 1999;19:5882-91. (Pubitemid 29399293)
44. Strauss 3rd JF, Kido S, Sayegh R, Sakuragi N, Gafvels ME. The cAMP signalling system and human trophoblast function. Placenta 1992;13:389-403.
45. Maymo JL, Perez Perez A, Duenas JL, Calvo JC, Sanchez-Margalet V, Varone CL. Regulation of placental leptin expression by cyclic adenosine 5′-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways. Endocrinology; 2010.
46. Mukherjee A, Park-Sarge OK, Mayo KE. Gonadotropins induce rapid phosphorylation of the 3′,5′-cyclic adenosine monophosphate response element binding protein in ovarian granulosa cells. Endocrinology 1996;137:3234-45. (Pubitemid 26250169)
47. Fitzgerald JS, Busch S, Wengenmayer T, Foerster K, de la Motte T, Poehlmann TG, et al. Signal transduction in trophoblast invasion. Chem Immunol Allergy 2005;88:181-99. (Pubitemid 43094385)
48. Hatano N, Mori Y, Oh-hora M, Kosugi A, Fujikawa T, Nakai N, et al. Essential role for ERK2 mitogen-activated protein kinase in placental development. Genes Cells 2003;8:847-56. (Pubitemid 37428014)
49. Gerits N, Kostenko S, Shiryaev A, Johannessen M, Moens U. Relations between the mitogen-activated protein kinase and the cAMP-dependent protein kinase pathways: comradeship and hostility. Cell Signal 2008;20:1592-607.
50. Bornfeldt KE, Krebs EG. Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle. Cell Signal 1999;11:465-77. (Pubitemid 29234116)
51. Shaywitz AJ, Greenberg ME. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 1999;68:821-61. (Pubitemid 29449210)
52. Kawasaki H, Springett GM, Mochizuki N, Toki S, Nakaya M, Matsuda M, et al. A family of cAMP-binding proteins that directly activate Rap1. Science 1998;282:2275-9. (Pubitemid 29004080)
53. Chen Z, Katzenellenbogen BS, Katzenellenbogen JA, Zhao H. Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity. J Biol Chem 2004;279:33855-64. (Pubitemid 39063035)
54. Acconcia F, Kumar R. Signaling regulation of genomic and nongenomic functions of estrogen receptors. Cancer Lett 2006;238:1-14. (Pubitemid 43851144)
55. O'Neil JS, Burow ME, Green AE, McLachlan JA, Henson MC. Effects of estrogen on leptin gene promoter activation in MCF-7 breast cancer and JEG-3 choriocarcinoma cells: selective regulation via estrogen receptors alpha and beta. Mol Cell Endocrinol 2001;176:67-75. (Pubitemid 32454936)
56. Gambino YP, Maymo JL, Perez-Perez A, Duenas JL, Sanchez-Margalet V, Calvo JC, et al. 17Beta-estradiol enhances leptin expression in human placental cells through genomic and nongenomic actions. Biol Reprod; 2010.
57. Beato M, Herrlich P, Schutz G. Steroid hormone receptors: many actors in search of a plot. Cell 1995;83:851-7. (Pubitemid 26006527)
58. Gaub MP, Bellard M, Scheuer I, Chambon P, Sassone-Corsi P. Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex. Cell 1990;63:1267-76. (Pubitemid 120035075)
59. Porter W, Saville B, Hoivik D, Safe S. Functional synergy between the transcription factor Sp1 and the estrogen receptor. Mol Endocrinol 1997;11:1569-80. (Pubitemid 27435406)
60. Wade CB, Robinson S, Shapiro RA, Dorsa DM. Estrogen receptor (ER)alpha and ERbeta exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway. Endocrinology 2001;142:2336-42. (Pubitemid 32473088)