Differential regulation of leptin synthesis in rats during short-term hypoxia and short-term carbon monoxide inhalation

Endocrinology

Volumn 146, Issue 1, 2005, Pages 215-220

  Meißner, Udo ^a   Hänisch, Claudia ^a   Östreicher, Iris ^a   Knerr, Ina ^a   Hofbauer, Karl Heinz ^b   Blum, Werner F ^c,d   Allabauer, Ida ^a   Rascher, Wolfgang ^a   Dötsch, Jörg ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c LILLY DEUTSCHLAND GMBH   (Germany)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; HYPOXIA INDUCIBLE FACTOR 1; LEPTIN; MESSENGER RNA; OXYGEN;

ADIPOSE TISSUE; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPOSURE; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HORMONAL REGULATION; HORMONE SYNTHESIS; HYPOXIA; INHALATION; KIDNEY; LIVER; LUNG; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; UPREGULATION;

ACUTE DISEASE; ADIPOSE TISSUE; ADMINISTRATION, INHALATION; ANIMALS; ANOXIA; CARBON MONOXIDE; DRUG ADMINISTRATION SCHEDULE; GENE EXPRESSION; KIDNEY; LEPTIN; LIVER; LUNG; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 11144246924     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-0782     Document Type: Article

References (44)

1. Ahima RS, Flier JS 2000 Leptin. Annu Rev Physiol 62:413-437
2. Senaris R, Garcia-Caballero T, Casabiell X, Gallego R, Castro R, Considine RV, Dieguez C, Casanueva FF 1997 Synthesis of leptin in human placenta. Endocrinology 138:4501-4504
3. Casabiell X, Pineiro V, Tome MA, Peino R, Dieguez C, Casanueva FF 1997 Presence of leptin in colostrum and/or breast milk from lactating mothers: a potential role in the regulation of neonatal food intake. J Clin Endocrinol Metab 82:4270-4273
4. Masuzaki H, Ogawa Y, Sagawa N, Hosoda K, Matsumoto T, Mise H, Nishimura H, Yoshimasa Y, Tanaka I, Mori T, Nakao K 1997 Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat Med 3:1029-1033
5. Bado A, Levasseur S, Attoub S, Kermorgant S, Laigneau JP, Bortoluzzi MN, Moizo L, Lehy T, Guerre-Millo M, Le Marchand-Brustel Y, Lewin MJ 1998 The stomach is a source of leptin. Nature 394:790-793
6. Wang J, Liu R, Hawkins M, Barzilai N, Rossetti L 1998 A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 393: 684-688
7. Purdham DM, Zou MX, Rajapurohitam V, Karmazyn M 2004 Rat heart is a site of leptin production and action. Am J Physiol Heart Circ Physiol 287: H2877-H2884
8. Ikejima K, Lang T, Zhang YJ, Yamashina S, Honda H, Yoshikawa M, Hirose M, Enomoto N, Kitamura T, Takei Y, Sato N 2004 Expression of leptin receptors in hepatic sinusoidal cells. Comp Hepatol 3(Suppl 1):S12
9. Saladin R, De Vos P, Guerre-Millo M, Leturque A, Girard J, Staels B, Auwerx J 1995 Transient increase in obese gene expression after food intake or insulin administration. Nature 377:527-529
10. Rentsch J, Chiesi M 1996 Regulation of ob gene mRNA levels in cultured adipocytes. FEBS Lett 379:55-59
11. Meissner U, Ostreicher I, Allabauer I, Rascher W, Dotsch J 2003 Synergistic effects of hypoxia and insulin are regulated by different transcriptional elements of the human leptin promoter. Biochem Biophys Res Commun 303: 707-712
12. Slieker LJ, Sloop KW, Surface PL, Kriauciunas A, LaQuier F, Manetta J, Bue-Valleskey J, Stephens TW 1996 Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP. J Biol Chem 271:5301-5304
13. Murakami T, Iida M, Shima K 1995 Dexamethasone regulates obese expression in isolated rat adipocytes. Biochem Biophys Res Commun 214:1260-1267
14. Grosfeld A, Turban S, Andre J, Cauzac M, Challier JC, Hauguel-de Mouzon S, Guerte-Millo M 2001 Transcriptional effect of hypoxia on placental leptin. FEBS Lett 502:122-126
15. Grosfeld A, Andre J, Hauguel-De Mouzon S, Berra E, Pouyssegur J, Guerre-Millo M 2002 Hypoxia-inducible factor 1 transactivates the human leptin gene promoter. J Biol Chem 277:42953-42957
16. Grosfeld A, Zilberfarb V, Turban S, Andre J, Guene-Millo M, Issad T 2002 Hypoxia increases leptin expression in human PAZ6 adipose cells. Diabetologia 45:527-530
17. Mise H, Sagawa N, Matsumoto T, Yura S, Nanno H, Itoh H, Mori T, Masuzaki H, Hosoda K, Ogawa Y, Nakao K 1998 Augmented placental production of leptin in preeclampsia: possible involvement of placental hypoxia. J Clin Endocrinol Metab 83:3225-3229
18. Schafer H, Pauleit D, Sudhop T, Gouni-Berthold I, Ewig S, Berthold HK 2002 Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea. Chest 122:829-839
19. Phipps PR, Starritt E, Caterson I, Grunstein RR 2002 Association of serum leptin with hypoventilation in human obesity. Thorax 57:75-76
20. Raff H, Bruder ED, Jankowski BM, Colman RJ 2001 Effect of neonatal hypoxia on leptin, insulin, growth hormone and body composition in the rat. Horm Metab Res 33:151-155
21. Raff H, Bruder ED, Jankowski BM 1999 The effect of hypoxia on plasma leptin and insulin in newborn and juvenile rats. Endocrine 11:37-39
22. Yasumasu T, Takahara K, Nakashima Y 2002 Hypoxia inhibits leptin production by cultured rat adipocytes. Obes Res 10:128
23. Rosenberger C, Mandriota S, Jurgensen JS, Wiesener MS, Horstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU 2002 Expression of hypoxia-inducible factor-1α and -2α in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 13:1721-1732
24. Liu Y, Christou H, Morita T, Laughner E, Semenza GL, Kourembanas S 1998 Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5′ enhancer. J Biol Chem 273:15257-15262
25. Huang LE, Willmore WG, Gu J, Goldberg MA, Bunn HF 1999 Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling. J Biol Chem 274:9038-9044
26. Hofbauer KH, Jensen BL, Kurtz A, Sandner P 2000 Tissue hypoxygenation activates the adrenomedullin system in vivo. Am J Physiol 278:R513-R519
27. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159
28. Dotsch J, Adelmann M, Englaro P, Dotsch A, Hanze J, Blum WF, Kiess W, Rascher W 1997 Relation of leptin and neuropeptide Y in human blood and cerebrospinal fluid. J Neurol Sci 151:185-188
29. Knerr I, Nyul Z, Miller J, Rosch W, Dotsch J, Repp R, Weidner W, Rascher W 2001 Increased endothelin-1 and decreased adrenomedullin gene expression in the stenotic tissue of congenital pelvi-ureteric junction obstruction in children. BJU Int 87:667-671
30. Okamoto Y, Arita Y, Nishida M, Muraguchi M, Ouchi N, Takahashi M, Igura T, Inui Y, Kihara S, Nakamura T, Yamashita S, Miyagawa J, Funahashi T, Matsuzawa Y 2000 An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res 32:47-50
31. Blum WF, Englaro P, Hanitsch S, Juul A, Hertel NT, Muller J, Skakkebaek NE, Heiman ML, Birkett M, Attanasio AM, Kiess W, Rascher W 1997 Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone. J Clin Endocrinol Metab 82:2904-2910
32. Serin E, Ozer B, Gumurdulu Y, Kayaselcuk F, Kul K, Boyacioglu S 2003 Serum leptin level can be a negative marker of hepatocyte damage in nonalcoholic fatty liver. J Gastroenterol 38:471-476
33. Fruhbeck G 2002 Peripheral actions of leptin and its involvement in disease. Nutr Rev 60:S47-S55
34. Ring BD, Scully S, Davis CR, Baker MB, Cullen MJ, Pelleymounter MA, Danilenko DM 2000 Systemically and topically administered leptin both accelerate wound healing in diabetic ob/ob mice. Endocrinology 141:446-449
35. Tschop M, Strasburger CJ, Topfer M, Hautmann H, Riepl R, Fischer R, Hartmann G, Morrison K, Appenzeller M, Hildebrandt W, Biollaz J, Bartsch P 2000 Influence of hypobaric hypoxia on leptin levels in men. Int J Obes Relat Metab Disord 24(Suppl 2):S151
36. Schoof E, Stuppy A, Harig F, Singer H, Carbon R, Horbach T, Kratzsch J, Rascher W, Dotsch J 2003 No influence of surgical stress on postoperative leptin gene expression in different adipose tissues and soluble leptin receptor plasma levels. Horm Res 59:184-190
37. Semenza GL 2001 HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 13:167-171
38. Semenza GL 2000 HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 88:1474-1480
39. Hodges MR, Forster HV, Papanek PE, Dwinell MR, Hogan GE 2002 Ventilatory phenotypes among four strains of adult rats. J Appl Physiol 93:974-983
40. Wolf G, Chen S, Han DC, Ziyadeh FN 2002 Leptin and renal disease. Am J Kidney Dis 39:1-11
41. Fantuzzi G, Faggioni R 2000 Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol 68:437-446
42. Wei M, Stern MP, Haffner SM 1997 Serum leptin levels in Mexican Americans and non-Hispanic whites: association with body mass index and cigarette smoking. Ann Epidemiol 7:81-86
43. Bates C, McNeill A, Jarvis M, Gray N 1999 The future of tobacco product regulation and labelling in Europe: implications for the forthcoming European Union directive. Tob Control 8:225-235
44. Perkins KA, Fonte C 2002 Effects of smoking status and smoking cessation on leptin levels. Nicotine Tob Res 4:459-466