-
2
-
-
67651162340
-
Immunobiology of asthma
-
Hamid, Q., and M. Tulic. 2009. Immunobiology of asthma. Annu. Rev. Physiol. 71: 489-507.
-
(2009)
Annu. Rev. Physiol.
, vol.71
, pp. 489-507
-
-
Hamid, Q.1
Tulic, M.2
-
3
-
-
77956643496
-
The role of eosinophils in allergic airway inflammation
-
Walsh, E. R., K. Stokes, and A. August. 2010. The role of eosinophils in allergic airway inflammation. Discov. Med. 9: 357-362.
-
(2010)
Discov. Med.
, vol.9
, pp. 357-362
-
-
Walsh, E.R.1
Stokes, K.2
August, A.3
-
4
-
-
45149085743
-
Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma
-
Walsh, E. R., N. Sahu, J. Kearley, E. Benjamin, B. H. Kang, A. Humbles, and A. August. 2008. Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma. J. Exp. Med. 205: 1285-1292.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1285-1292
-
-
Walsh, E.R.1
Sahu, N.2
Kearley, J.3
Benjamin, E.4
Kang, B.H.5
Humbles, A.6
August, A.7
-
5
-
-
84906281796
-
Re-defining the unique roles for eosinophils in allergic respiratory inflammation
-
Jacobsen, E. A., N. A. Lee, and J. J. Lee. 2014. Re-defining the unique roles for eosinophils in allergic respiratory inflammation. Clin. Exp. Allergy 44: 1119-1136.
-
(2014)
Clin. Exp. Allergy
, vol.44
, pp. 1119-1136
-
-
Jacobsen, E.A.1
Lee, N.A.2
Lee, J.J.3
-
6
-
-
41149176997
-
Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells
-
Jacobsen, E. A., S. I. Ochkur, R. S. Pero, A. G. Taranova, C. A. Protheroe, D. C. Colbert, N. A. Lee, and J. J. Lee. 2008. Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells. J. Exp. Med. 205: 699-710.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 699-710
-
-
Jacobsen, E.A.1
Ochkur, S.I.2
Pero, R.S.3
Taranova, A.G.4
Protheroe, C.A.5
Colbert, D.C.6
Lee, N.A.7
Lee, J.J.8
-
7
-
-
79952749924
-
Computational and experimental analysis reveals a requirement for eosinophilderived IL-13 for the development of allergic airway responses in C57BL/6 mice
-
Walsh, E., J. Thakar, K. Stokes, F. Huang, R. Albert, and A. August. 2011. Computational and experimental analysis reveals a requirement for eosinophilderived IL-13 for the development of allergic airway responses in C57BL/6 mice. J. Immunol. 186: 2936-2949.
-
(2011)
J. Immunol.
, vol.186
, pp. 2936-2949
-
-
Walsh, E.1
Thakar, J.2
Stokes, K.3
Huang, F.4
Albert, R.5
August, A.6
-
8
-
-
79955574671
-
Transcriptional regulation by STAT6
-
Goenka, S., and M. H. Kaplan. 2011. Transcriptional regulation by STAT6. Immunol. Res. 50: 87-96.
-
(2011)
Immunol. Res.
, vol.50
, pp. 87-96
-
-
Goenka, S.1
Kaplan, M.H.2
-
9
-
-
0032536837
-
Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
-
Kuperman, D., B. Schofield, M. Wills-Karp, and M. J. Grusby. 1998. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J. Exp. Med. 187: 939-948.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 939-948
-
-
Kuperman, D.1
Schofield, B.2
Wills-Karp, M.3
Grusby, M.J.4
-
10
-
-
5044251100
-
STAT6-mediated signaling in Th2-dependent allergic asthma: Critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation
-
Hoshino, A., T. Tsuji, J. Matsuzaki, T. Jinushi, S. Ashino, T. Teramura, K. Chamoto, Y. Tanaka, Y. Asakura, T. Sakurai, et al. 2004. STAT6-mediated signaling in Th2-dependent allergic asthma: critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation. Int. Immunol. 16: 1497-1505.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1497-1505
-
-
Hoshino, A.1
Tsuji, T.2
Matsuzaki, J.3
Jinushi, T.4
Ashino, S.5
Teramura, T.6
Chamoto, K.7
Tanaka, Y.8
Asakura, Y.9
Sakurai, T.10
-
11
-
-
0033761127
-
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase-and cathepsin-dependent emphysema
-
Zheng, T., Z. Zhu, Z. Wang, R. J. Homer, B. Ma, R. J. Riese, Jr., H. A. Chapman, Jr., S. D. Shapiro, and J. A. Elias. 2000. Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase-and cathepsin-dependent emphysema. J. Clin. Invest. 106: 1081-1093.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1081-1093
-
-
Zheng, T.1
Zhu, Z.2
Wang, Z.3
Homer, R.J.4
Ma, B.5
Riese, R.J.6
Chapman, H.A.7
Shapiro, S.D.8
Elias, J.A.9
-
12
-
-
0034235875
-
Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity
-
Webb, D. C., A. N. McKenzie, A. M. Koskinen, M. Yang, J. Mattes, and P. S. Foster. 2000. Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity. J. Immunol. 165: 108-113.
-
(2000)
J. Immunol.
, vol.165
, pp. 108-113
-
-
Webb, D.C.1
McKenzie, A.N.2
Koskinen, A.M.3
Yang, M.4
Mattes, J.5
Foster, P.S.6
-
13
-
-
9644281044
-
Interleukin-13 in asthma pathogenesis
-
Wills-Karp, M. 2004. Interleukin-13 in asthma pathogenesis. Immunol. Rev. 202: 175-190.
-
(2004)
Immunol. Rev.
, vol.202
, pp. 175-190
-
-
Wills-Karp, M.1
-
14
-
-
0037013924
-
Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo
-
Yu, C., A. B. Cantor, H. Yang, C. Browne, R. A. Wells, Y. Fujiwara, and S. H. Orkin. 2002. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. J. Exp. Med. 195: 1387-1395.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1387-1395
-
-
Yu, C.1
Cantor, A.B.2
Yang, H.3
Browne, C.4
Wells, R.A.5
Fujiwara, Y.6
Orkin, S.H.7
-
15
-
-
0031068013
-
Expression of IL-5 in thymocytes/T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies
-
Lee, N. A., M. P. McGarry, K. A. Larson, M. A. Horton, A. B. Kristensen, and J. J. Lee. 1997. Expression of IL-5 in thymocytes/T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies. J. Immunol. 158: 1332-1344.
-
(1997)
J. Immunol.
, vol.158
, pp. 1332-1344
-
-
Lee, N.A.1
McGarry, M.P.2
Larson, K.A.3
Horton, M.A.4
Kristensen, A.B.5
Lee, J.J.6
-
16
-
-
44849086094
-
Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migration
-
Sahu, N., C. Mueller, A. Fischer, and A. August. 2008. Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migration. J. Immunol. 180: 3833-3838.
-
(2008)
J. Immunol.
, vol.180
, pp. 3833-3838
-
-
Sahu, N.1
Mueller, C.2
Fischer, A.3
August, A.4
-
17
-
-
3142727906
-
Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK
-
Fischer, A. M., J. C. Mercer, A. Iyer, M. J. Ragin, and A. August. 2004. Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK. J. Biol. Chem. 279: 29816-29820.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29816-29820
-
-
Fischer, A.M.1
Mercer, J.C.2
Iyer, A.3
Ragin, M.J.4
August, A.5
-
18
-
-
84863004070
-
IL-4 engagement of the type i IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro
-
Heller, N. M., W. M. Gwinn, R. P. Donnelly, S. L. Constant, and A. D. Keegan. 2012. IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro. PLoS ONE 7: e39673.
-
(2012)
PLoS ONE
, vol.7
, pp. e39673
-
-
Heller, N.M.1
Gwinn, W.M.2
Donnelly, R.P.3
Constant, S.L.4
Keegan, A.D.5
-
19
-
-
84910013639
-
STAT6 and lung inflammation
-
Walford, H. H., and T. A. Doherty. 2013. STAT6 and lung inflammation. JAKSTAT 2: e25301.
-
(2013)
JAKSTAT
, vol.2
, pp. e25301
-
-
Walford, H.H.1
Doherty, T.A.2
-
20
-
-
82755162138
-
Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation
-
Jacobsen, E. A., K. R. Zellner, D. Colbert, N. A. Lee, and J. J. Lee. 2011. Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation. J. Immunol. 187: 6059-6068.
-
(2011)
J. Immunol.
, vol.187
, pp. 6059-6068
-
-
Jacobsen, E.A.1
Zellner, K.R.2
Colbert, D.3
Lee, N.A.4
Lee, J.J.5
-
22
-
-
34249798763
-
Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling
-
Fulkerson, P. C., C. A. Fischetti, and M. E. Rothenberg. 2006. Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling. Am. J. Pathol. 169: 2117-2126.
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 2117-2126
-
-
Fulkerson, P.C.1
Fischetti, C.A.2
Rothenberg, M.E.3
-
23
-
-
0036199934
-
CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation
-
Ma, W., P. J. Bryce, A. A. Humbles, D. Laouini, A. Yalcindag, H. Alenius, D. S. Friend, H. C. Oettgen, C. Gerard, and R. S. Geha. 2002. CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation. J. Clin. Invest. 109: 621-628.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 621-628
-
-
Ma, W.1
Bryce, P.J.2
Humbles, A.A.3
Laouini, D.4
Yalcindag, A.5
Alenius, H.6
Friend, D.S.7
Oettgen, H.C.8
Gerard, C.9
Geha, R.S.10
-
24
-
-
0037022386
-
The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness
-
Humbles, A. A., B. Lu, D. S. Friend, S. Okinaga, J. Lora, A. Al-Garawi, T. R. Martin, N. P. Gerard, and C. Gerard. 2002. The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proc. Natl. Acad. Sci. USA 99: 1479-1484.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1479-1484
-
-
Humbles, A.A.1
Lu, B.2
Friend, D.S.3
Okinaga, S.4
Lora, J.5
Al-Garawi, A.6
Martin, T.R.7
Gerard, N.P.8
Gerard, C.9
-
25
-
-
0032482159
-
Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice
-
Akimoto, T., F. Numata, M. Tamura, Y. Takata, N. Higashida, T. Takashi, K. Takeda, and S. Akira. 1998. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice. J. Exp. Med. 187: 1537-1542.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1537-1542
-
-
Akimoto, T.1
Numata, F.2
Tamura, M.3
Takata, Y.4
Higashida, N.5
Takashi, T.6
Takeda, K.7
Akira, S.8
-
26
-
-
79951828807
-
STAT6 expression in multiple cell types mediates the cooperative development of allergic airway disease
-
Chapoval, S. P., P. Dasgupta, E. P. Smith, L. J. DeTolla, M. M. Lipsky, A. E. Kelly-Welch, and A. D. Keegan. 2011. STAT6 expression in multiple cell types mediates the cooperative development of allergic airway disease. J. Immunol. 186: 2571-2583.
-
(2011)
J. Immunol.
, vol.186
, pp. 2571-2583
-
-
Chapoval, S.P.1
Dasgupta, P.2
Smith, E.P.3
Detolla, L.J.4
Lipsky, M.M.5
Kelly-Welch, A.E.6
Keegan, A.D.7
-
27
-
-
0035821221
-
Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation
-
Mathew, A., J. A. MacLean, E. DeHaan, A. M. Tager, F. H. Green, and A. D. Luster. 2001. Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation. J. Exp. Med. 193: 1087-1096.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1087-1096
-
-
Mathew, A.1
Maclean, J.A.2
Dehaan, E.3
Tager, A.M.4
Green, F.H.5
Luster, A.D.6
-
28
-
-
24744469212
-
Induction of surface CCR4 and its functionality in mouse Th2 cells is regulated differently during Th2 development
-
Morimoto, Y., Y. Bian, P. Gao, Y. Yashiro-Ohtani, X. Y. Zhou, S. Ono, H. Nakahara, M. Kogo, T. Hamaoka, and H. Fujiwara. 2005. Induction of surface CCR4 and its functionality in mouse Th2 cells is regulated differently during Th2 development. J. Leukoc. Biol. 78: 753-761.
-
(2005)
J. Leukoc. Biol.
, vol.78
, pp. 753-761
-
-
Morimoto, Y.1
Bian, Y.2
Gao, P.3
Yashiro-Ohtani, Y.4
Zhou, X.Y.5
Ono, S.6
Nakahara, H.7
Kogo, M.8
Hamaoka, T.9
Fujiwara, H.10
-
29
-
-
0033905684
-
STAT6 is required for the regulation of IL-4-induced cytoskeletal events in B cells
-
Davey, E. J., G. Greicius, J. Thyberg, and E. Severinson. 2000. STAT6 is required for the regulation of IL-4-induced cytoskeletal events in B cells. Int. Immunol. 12: 995-1003.
-
(2000)
Int. Immunol.
, vol.12
, pp. 995-1003
-
-
Davey, E.J.1
Greicius, G.2
Thyberg, J.3
Severinson, E.4
-
30
-
-
84885456137
-
IL-33 markedly activates murine eosinophils by an NF-kB-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop
-
Bouffi, C., M. Rochman, C. B. Zust, E. M. Stucke, A. Kartashov, P. C. Fulkerson, A. Barski, and M. E. Rothenberg. 2013. IL-33 markedly activates murine eosinophils by an NF-kB-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop. J. Immunol. 191: 4317-4325.
-
(2013)
J. Immunol.
, vol.191
, pp. 4317-4325
-
-
Bouffi, C.1
Rochman, M.2
Zust, C.B.3
Stucke, E.M.4
Kartashov, A.5
Fulkerson, P.C.6
Barski, A.7
Rothenberg, M.E.8
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