Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen

Journal of Immunology

Volumn 194, Issue 6, 2015, Pages 2673-2682

  Onishi, Motoyasu ^a,b,c   Ozasa, Koji ^a   Kobiyama, Kouji ^a,b   Ohata, Keiichi ^a,b   Kitano, Mitsutaka ^c   Taniguchi, Keiichi ^c   Homma, Tomoyuki ^c   Kobayashi, Masanori ^c   Sato, Akihiko ^c   Katakai, Yuko ^d   Yasutomi, Yasuhiro ^a   Wijaya, Edward ^b   Igarashi, Yoshinobu ^a   Nakatsu, Noriyuki ^a   Ise, Wataru ^b   Inoue, Takeshi ^b   Yamada, Hiroshi ^e   Vandenbon, Alexis ^b   Standley, Daron M ^b   Kurosaki, Tomohiro ^b,e   Coban, Cevayir ^b   Aoshi, Taiki ^a,b   Kuroda, Etsushi ^a,b   Ishii, Ken J ^a,b   more..

^a NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c SHIONOGI AND CO LTD   (Japan)

^d The Corporation for Production and Research of Laboratory Primates   (Japan)

^e RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ALUMINUM SALT; DEOXYRIBONUCLEASE; DOUBLE STRANDED DNA; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G ANTIBODY; INFLUENZA VACCINE; MYELOID DIFFERENTIATION FACTOR 88; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN; ANTIGEN; BETA CYCLODEXTRIN DERIVATIVE; IMMUNOLOGICAL ADJUVANT; TRANSCRIPTOME;

2009 H1N1 INFLUENZA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HELPER CELL; IMMUNIZATION; INFLAMMATION; INFLUENZA VACCINATION; INJECTION SITE; INNATE IMMUNITY; MACACA; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; T FOLLICULAR HELPER CELL; TH2 CELL; ANIMAL; ANTIBODY PRODUCTION; C57BL MOUSE; DNA MICROARRAY; DRUG EFFECTS; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INFLUENZA VIRUS A H1N1; KNOCKOUT MOUSE; LYMPH NODE; MACACA FASCICULARIS; METABOLISM; MULTIPHOTON MICROSCOPY; ORTHOMYXOVIRIDAE INFECTIONS; PHYSIOLOGY; SPLEEN; VIROLOGY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODY FORMATION; ANTIGENS; BETA-CYCLODEXTRINS; HOST-PATHOGEN INTERACTIONS; INFLAMMATION; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA VACCINES; LYMPH NODES; MACACA FASCICULARIS; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORTHOMYXOVIRIDAE INFECTIONS; SPLEEN; T-LYMPHOCYTES, HELPER-INDUCER; TH2 CELLS; TRANSCRIPTOME;

EID: 84924559869     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402027     Document Type: Article

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