Inflammasomes induced by 7-ketocholesterol and other stimuli in rpe and in bone marrow-derived cells differ markedly in their production of IL-1β and IL-18

Investigative Ophthalmology and Visual Science

Volumn 56, Issue 3, 2015, Pages 1658-1664

  Shi, Guangpu ^a   Chen, Siqi ^a   Wandu, Wambui S ^a   Ogbeifun, Osato ^a   Nugent, Lindsey F ^a   Maminishkis, Arvydas ^a   Hinshaw, Samuel J H ^a   Rodriguez, Ignacio R ^a   Gery, Igal ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

Bone marrow derived cells; IL 1; IL 18; Inflammasomes; RPE cells

Indexed keywords

7 OXOCHOLESTEROL; CHOLESTEROL; COLONY STIMULATING FACTOR 1; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; SILICON DIOXIDE; 7-KETOCHOLESTEROL; CHOLESTEROL DERIVATIVE;

AGE RELATED MACULAR DEGENERATION; ARPE19 CELL LINE; ARTICLE; BONE MARROW DERIVED MAST CELL; CELL LINE; CHEMOLUMINESCENCE; CHOROID; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; MICROGLIA; PIGMENT EPITHELIUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RNA EXTRACTION; THP 1 CELL LINE; WESTERN BLOTTING; BONE MARROW CELL; CELL CULTURE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; RETINAL PIGMENT EPITHELIUM;

BLOTTING, WESTERN; BONE MARROW CELLS; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; KETOCHOLESTEROLS; RETINAL PIGMENT EPITHELIUM;

EID: 84924559361     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.14-14557     Document Type: Article

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