-
1
-
-
84860133437
-
Lentiviral vectors: Basic to translational
-
Sakuma, T., Barry, M. A. & Ikeda, Y. Lentiviral vectors: basic to translational. Biochem J 443, 603-618, doi:10.1042/bj20120146 (2012).
-
(2012)
Biochem J
, vol.443
, pp. 603-618
-
-
Sakuma, T.1
Barry, M.A.2
Ikeda, Y.3
-
2
-
-
79954692758
-
Ex vivo gene transfer and correction for cell-based therapies
-
Naldini, L. Ex vivo gene transfer and correction for cell-based therapies. Nature reviews. Genetics 12, 301-315, doi:10.1038/nrg2985 (2011).
-
(2011)
Nature Reviews. Genetics
, vol.12
, pp. 301-315
-
-
Naldini, L.1
-
3
-
-
79954650563
-
State-of-the-art gene-based therapies: The road ahead
-
Kay, M. A. State-of-the-art gene-based therapies: the road ahead. Nature reviews. Genetics 12, 316-328, doi:10.1038/nrg2971 (2011).
-
(2011)
Nature Reviews. Genetics
, vol.12
, pp. 316-328
-
-
Kay, M.A.1
-
4
-
-
84877575144
-
Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors. Nature reviews
-
Kochenderfer, J. N. & Rosenberg, S. A. Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors. Nature reviews. Clinical oncology 10, 267-276, doi:10.1038/nrclinonc.2013.46 (2013).
-
(2013)
Clinical Oncology
, vol.10
, pp. 267-276
-
-
Kochenderfer, J.N.1
Rosenberg, S.A.2
-
6
-
-
0036848194
-
HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation
-
Nie, Z. et al. HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation. Cell death and differentiation 9, 1172-1184, doi:10.1038/sj.cdd.4401094 (2002).
-
(2002)
Cell Death and Differentiation
, vol.9
, pp. 1172-1184
-
-
Nie, Z.1
-
7
-
-
78049408241
-
Fusion-active glycoprotein G mediates the cytotoxicity of vesicular stomatitis virus M mutants lacking host shut-off activity
-
Hoffmann, M. et al. Fusion-active glycoprotein G mediates the cytotoxicity of vesicular stomatitis virus M mutants lacking host shut-off activity. The Journal of general virology 91, 2782-2793, doi:10.1099/vir.0.023978-0 (2010).
-
(2010)
The Journal of General Virology
, vol.91
, pp. 2782-2793
-
-
Hoffmann, M.1
-
8
-
-
77956928344
-
Transfusion independence and HMGA2 activation after gene therapy of human beta-thalassaemia
-
Cavazzana-Calvo, M. et al. Transfusion independence and HMGA2 activation after gene therapy of human beta-thalassaemia. Nature 467, 318-322, doi:10.1038/nature09328 (2010).
-
(2010)
Nature
, vol.467
, pp. 318-322
-
-
Cavazzana-Calvo, M.1
-
9
-
-
70449427834
-
Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
-
Cartier, N. et al. Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. Science 326, 818-823, doi:10.1126/science.1171242 (2009).
-
(2009)
Science
, vol.326
, pp. 818-823
-
-
Cartier, N.1
-
10
-
-
84879873039
-
Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy
-
Biffi, A. et al. Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy. Science, doi:10.1126/science.1233158 (2013).
-
(2013)
Science
-
-
Biffi, A.1
-
11
-
-
84879867061
-
Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome
-
Aiuti, A. et al. Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome. Science, doi:10.1126/science.1233151 (2013).
-
(2013)
Science
-
-
Aiuti, A.1
-
12
-
-
84876475656
-
Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV
-
Tebas, P. et al. Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV. Blood 121, 1524-1533, doi:10.1182/blood-2012-07-447250 (2013).
-
(2013)
Blood
, vol.121
, pp. 1524-1533
-
-
Tebas, P.1
-
13
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos, M. et al. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Science translational medicine 3, 95ra73, doi:10.1126/scitranslmed.3002842 (2011).
-
(2011)
Science Translational Medicine
, vol.3
, pp. 95ra73
-
-
Kalos, M.1
-
14
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter, D. L., Levine, B. L., Kalos, M., Bagg, A. & June, C. H. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. The New England journal of medicine 365, 725-733, doi:10.1056/NEJMoa1103849 (2011).
-
(2011)
The New England Journal of Medicine
, vol.365
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
Bagg, A.4
June, C.H.5
-
15
-
-
33846081072
-
Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9
-
Pichlmair, A. et al. Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9. J Virol 81, 539-547, doi:10.1128/jvi.01818-06 (2007).
-
(2007)
J Virol
, vol.81
, pp. 539-547
-
-
Pichlmair, A.1
-
16
-
-
67149117119
-
Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection
-
Throm, R. E. et al. Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection. Blood 113, 5104-5110, doi:10.1182/blood-2008-11-191049 (2009).
-
(2009)
Blood
, vol.113
, pp. 5104-5110
-
-
Throm, R.E.1
-
17
-
-
84878746232
-
Transduction of human CD34+ repopulating cells with a self-inactivating lentiviral vector for SCID-X1 produced at clinical scale by a stable cell line
-
Greene, M. R. et al. Transduction of human CD34+ repopulating cells with a self-inactivating lentiviral vector for SCID-X1 produced at clinical scale by a stable cell line. Human gene therapy methods 23, 297-308, doi:10.1089/hgtb.2012.150 (2012).
-
(2012)
Human Gene Therapy Methods
, vol.23
, pp. 297-308
-
-
Greene, M.R.1
-
18
-
-
67349240866
-
Development of inducible EIAV-based lentiviral vector packaging and producer cell lines
-
Stewart, H. J., Leroux-Carlucci, M. A., Sion, C. J., Mitrophanous, K. A. & Radcliffe, P. A. Development of inducible EIAV-based lentiviral vector packaging and producer cell lines. Gene Ther 16, 805-814, doi:10.1038/gt.2009.20 (2009).
-
(2009)
Gene Ther
, vol.16
, pp. 805-814
-
-
Stewart, H.J.1
Leroux-Carlucci, M.A.2
Sion, C.J.3
Mitrophanous, K.A.4
Radcliffe, P.A.5
-
19
-
-
79952686685
-
A stable producer cell line for the manufacture of a lentiviral vector for gene therapy of Parkinson's disease
-
Stewart, H. J. et al. A stable producer cell line for the manufacture of a lentiviral vector for gene therapy of Parkinson's disease. Hum Gene Ther 22, 357-369, doi:10.1089/hum.2010.142 (2011).
-
(2011)
Hum Gene Ther
, vol.22
, pp. 357-369
-
-
Stewart, H.J.1
-
20
-
-
21044453936
-
Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector
-
Ni, Y. et al. Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector. J Gene Med 7, 818-834, doi:10.1002/jgm.726 (2005).
-
(2005)
J Gene Med
, vol.7
, pp. 818-834
-
-
Ni, Y.1
-
21
-
-
39849094316
-
Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture
-
Broussau, S. et al. Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture. Mol Ther 16, 500-507, doi:10.1038/sj.mt.6300383 (2008).
-
(2008)
Mol Ther
, vol.16
, pp. 500-507
-
-
Broussau, S.1
-
22
-
-
0034914353
-
A new-generation stable inducible packaging cell line for lentiviral vectors
-
Farson, D. et al. A new-generation stable inducible packaging cell line for lentiviral vectors. Hum Gene Ther 12, 981-997, doi:10.1089/104303401750195935 (2001).
-
(2001)
Hum Gene Ther
, vol.12
, pp. 981-997
-
-
Farson, D.1
-
23
-
-
0038333587
-
Continuous high-titer HIV-1 vector production
-
Ikeda, Y. et al. Continuous high-titer HIV-1 vector production. Nat Biotechnol 21, 569-572, doi:10.1038/nbt815 (2003).
-
(2003)
Nat Biotechnol
, vol.21
, pp. 569-572
-
-
Ikeda, Y.1
-
24
-
-
14044263641
-
Gene transfer to repopulating human CD34+ cells using amphotropic-, GALV-, or RD114-pseudotyped HIV-1-based vectors from stable producer cells
-
Relander, T. et al. Gene transfer to repopulating human CD34+ cells using amphotropic-, GALV-, or RD114-pseudotyped HIV-1-based vectors from stable producer cells. Mol Ther 11, 452-459, doi:10.1016/j.ymthe.2004.10.014 (2005).
-
(2005)
Mol Ther
, vol.11
, pp. 452-459
-
-
Relander, T.1
-
25
-
-
0036682935
-
Lentiviral vectors pseudotyped with amodified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates
-
Sandrin, V. et al. Lentiviral vectors pseudotyped with amodified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates. Blood 100, 823-832, doi:10.1182/blood-2001-11-0042 (2002).
-
(2002)
Blood
, vol.100
, pp. 823-832
-
-
Sandrin, V.1
-
26
-
-
0141889328
-
Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD341 cells
-
Brenner, S. et al. Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD341 cells. Blood 102, 2789-2797, doi:10.1182/blood-2002-05-1482 (2003).
-
(2003)
Blood
, vol.102
, pp. 2789-2797
-
-
Brenner, S.1
-
27
-
-
84883002841
-
RD2-MolPack-Chim3, a packaging cell line for stable production of lentiviral vectors for anti-HIV gene therapy
-
Stornaiuolo, A. et al. RD2-MolPack-Chim3, a packaging cell line for stable production of lentiviral vectors for anti-HIV gene therapy. Human gene therapy methods, doi:10.1089/hgtb.2012.190 (2013).
-
(2013)
Human Gene Therapy Methods
-
-
Stornaiuolo, A.1
-
28
-
-
80052327308
-
Host cells and cell banking
-
Stacey, G. N. & Merten, O. W. Host cells and cell banking. Methods in molecular biology (Clifton, N. J.) 737, 45-88, doi:10.1007/978-1-61779-095-9-3 (2011).
-
(2011)
Methods in Molecular Biology (Clifton, N. J.)
, vol.737
, pp. 45-88
-
-
Stacey, G.N.1
Merten, O.W.2
-
29
-
-
0030809406
-
Targeted integration of DNA using mutant lox sites in embryonic stem cells
-
Araki, K., Araki, M. & Yamamura, K. Targeted integration of DNA using mutant lox sites in embryonic stem cells. Nucleic Acids Res 25, 868-872 (1997).
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 868-872
-
-
Araki, K.1
Araki, M.2
Yamamura, K.3
-
31
-
-
6344228445
-
Influence of gag on human immunodeficiency virus type 1 species-specific tropism
-
Ikeda, Y., Ylinen, L. M., Kahar-Bador, M. & Towers, G. J. Influence of gag on human immunodeficiency virus type 1 species-specific tropism. J Virol 78, 11816-11822 (2004).
-
(2004)
J Virol
, vol.78
, pp. 11816-11822
-
-
Ikeda, Y.1
Ylinen, L.M.2
Kahar-Bador, M.3
Towers, G.J.4
-
32
-
-
28844479566
-
Naturally occurring capsid substitutions render HIV-1 cyclophilin Aindependent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells
-
Chatterji, U. et al. Naturally occurring capsid substitutions render HIV-1 cyclophilin Aindependent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells. J Biol Chem 280, 40293-40300 (2005).
-
(2005)
J Biol Chem
, vol.280
, pp. 40293-40300
-
-
Chatterji, U.1
-
33
-
-
34648840100
-
The presence of the Trim5alpha escape mutation H87Q in the capsid of late stage HIV-1 variants is preceded by a prolonged asymptomatic infection phase
-
Kootstra, N. A., Navis, M., Beugeling, C., van Dort, K. A. & Schuitemaker, H. The presence of the Trim5alpha escape mutation H87Q in the capsid of late stage HIV-1 variants is preceded by a prolonged asymptomatic infection phase. Aids 21, 2015-2023, doi:10.1097/QAD.0b013e3282effa87 (2007).
-
(2007)
Aids
, vol.21
, pp. 2015-2023
-
-
Kootstra, N.A.1
Navis, M.2
Beugeling, C.3
Van Dort, K.A.4
Schuitemaker, H.5
-
34
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey, R. et al. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 72, 9873-9880 (1998).
-
(1998)
J Virol
, vol.72
, pp. 9873-9880
-
-
Zufferey, R.1
-
35
-
-
65249101260
-
The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
-
Montini, E. et al. The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy. The Journal of clinical investigation 119, 964-975, doi:10.1172/jci37630 (2009).
-
(2009)
The Journal of Clinical Investigation
, vol.119
, pp. 964-975
-
-
Montini, E.1
-
36
-
-
70449127230
-
Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors
-
Modlich, U. et al. Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors. Mol Ther 17, 1919-1928, doi:10.1038/mt.2009.179 (2009).
-
(2009)
Mol Ther
, vol.17
, pp. 1919-1928
-
-
Modlich, U.1
-
37
-
-
0033780046
-
Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
-
O'Doherty, U., Swiggard, W. J. & Malim, M. H. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding. J Virol 74, 10074-10080 (2000).
-
(2000)
J Virol
, vol.74
, pp. 10074-10080
-
-
O'Doherty, U.1
Swiggard, W.J.2
Malim, M.H.3
-
38
-
-
1842429029
-
Characterization of HIV-1 vectors with gammaretrovirus envelope glycoproteins produced from stable packaging cells
-
Strang, B. L., Ikeda, Y., Cosset, F. L., Collins, M. K. & Takeuchi, Y. Characterization of HIV-1 vectors with gammaretrovirus envelope glycoproteins produced from stable packaging cells. Gene Ther 11, 591-598, doi:10.1038/sj.gt.3302189 (2004).
-
(2004)
Gene Ther
, vol.11
, pp. 591-598
-
-
Strang, B.L.1
Ikeda, Y.2
Cosset, F.L.3
Collins, M.K.4
Takeuchi, Y.5
-
39
-
-
77957825561
-
RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectors
-
Bell, A. J., Jr., Fegen, D., Ward, M. & Bank, A. RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectors. Exp Biol Med (Maywood) 235, 1269-1276, doi:10.1258/ebm.2010.010053 (2010).
-
(2010)
Exp Biol Med (Maywood)
, vol.235
, pp. 1269-1276
-
-
Bell, A.J.1
Fegen, D.2
Ward, M.3
Bank, A.4
-
41
-
-
0037043699
-
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
-
Sheehy, A. M., Gaddis, N. C., Choi, J. D. & Malim, M. H. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 418, 646-650, doi:10.1038/nature00939 (2002).
-
(2002)
Nature
, vol.418
, pp. 646-650
-
-
Sheehy, A.M.1
Gaddis, N.C.2
Choi, J.D.3
Malim, M.H.4
-
42
-
-
79955939275
-
APOBEC3-mediated hypermutation of retroviral vectors produced from some retrovirus packaging cell lines
-
Miller, A. D. & Metzger, M. J. APOBEC3-mediated hypermutation of retroviral vectors produced from some retrovirus packaging cell lines. Gene Ther 18, 528-530, doi:10.1038/gt.2010.177 (2011).
-
(2011)
Gene Ther
, vol.18
, pp. 528-530
-
-
Miller, A.D.1
Metzger, M.J.2
-
43
-
-
34250688401
-
All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition
-
Kinomoto, M. et al. All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition. Nucleic Acids Res 35, 2955-2964, doi:10.1093/nar/gkm181 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 2955-2964
-
-
Kinomoto, M.1
-
44
-
-
84879883823
-
Gene therapy for PIDs: Progress, pitfalls and prospects
-
Mukherjee, S. & Thrasher, A. J. Gene therapy for PIDs: Progress, pitfalls and prospects. Gene, doi:10.1016/j.gene.2013.03.098 (2013).
-
(2013)
Gene
-
-
Mukherjee, S.1
Thrasher, A.J.2
-
45
-
-
0030819379
-
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
-
Zufferey, R., Nagy, D., Mandel, R. J., Naldini, L. & Trono, D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol 15, 871-875, doi:10.1038/nbt0997-871 (1997).
-
(1997)
Nat Biotechnol
, vol.15
, pp. 871-875
-
-
Zufferey, R.1
Nagy, D.2
Mandel, R.J.3
Naldini, L.4
Trono, D.5
-
46
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L. et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267 (1996).
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
-
47
-
-
0026566559
-
DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood
-
Bergsagel, D. J., Finegold, M. J., Butel, J. S., Kupsky, W. J. & Garcea, R. L. DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood. The New England journal of medicine 326, 988-993, doi:10.1056/nejm199204093261504 (1992).
-
(1992)
The New England Journal of Medicine
, vol.326
, pp. 988-993
-
-
Bergsagel, D.J.1
Finegold, M.J.2
Butel, J.S.3
Kupsky, W.J.4
Garcea, R.L.5
-
48
-
-
1142309492
-
Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment
-
Sastry, L., Xu, Y., Cooper, R., Pollok, K. & Cornetta, K. Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment. Hum Gene Ther 15, 221-226, doi:10.1089/104303404772680029 (2004).
-
(2004)
Hum Gene Ther
, vol.15
, pp. 221-226
-
-
Sastry, L.1
Xu, Y.2
Cooper, R.3
Pollok, K.4
Cornetta, K.5
|