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Volumn 5, Issue , 2015, Pages

Construction of stable packaging cell lines for clinical lentiviral vector production

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; POL PROTEIN; PR160 GAG-POL PRECURSOR PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; PROTEIN PRECURSOR; REV PROTEIN; REV PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS-1; VIRUS ENVELOPE PROTEIN;

EID: 84924546283     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep09021     Document Type: Article
Times cited : (77)

References (48)
  • 1
    • 84860133437 scopus 로고    scopus 로고
    • Lentiviral vectors: Basic to translational
    • Sakuma, T., Barry, M. A. & Ikeda, Y. Lentiviral vectors: basic to translational. Biochem J 443, 603-618, doi:10.1042/bj20120146 (2012).
    • (2012) Biochem J , vol.443 , pp. 603-618
    • Sakuma, T.1    Barry, M.A.2    Ikeda, Y.3
  • 2
    • 79954692758 scopus 로고    scopus 로고
    • Ex vivo gene transfer and correction for cell-based therapies
    • Naldini, L. Ex vivo gene transfer and correction for cell-based therapies. Nature reviews. Genetics 12, 301-315, doi:10.1038/nrg2985 (2011).
    • (2011) Nature Reviews. Genetics , vol.12 , pp. 301-315
    • Naldini, L.1
  • 3
    • 79954650563 scopus 로고    scopus 로고
    • State-of-the-art gene-based therapies: The road ahead
    • Kay, M. A. State-of-the-art gene-based therapies: the road ahead. Nature reviews. Genetics 12, 316-328, doi:10.1038/nrg2971 (2011).
    • (2011) Nature Reviews. Genetics , vol.12 , pp. 316-328
    • Kay, M.A.1
  • 4
    • 84877575144 scopus 로고    scopus 로고
    • Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors. Nature reviews
    • Kochenderfer, J. N. & Rosenberg, S. A. Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors. Nature reviews. Clinical oncology 10, 267-276, doi:10.1038/nrclinonc.2013.46 (2013).
    • (2013) Clinical Oncology , vol.10 , pp. 267-276
    • Kochenderfer, J.N.1    Rosenberg, S.A.2
  • 6
    • 0036848194 scopus 로고    scopus 로고
    • HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation
    • Nie, Z. et al. HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation. Cell death and differentiation 9, 1172-1184, doi:10.1038/sj.cdd.4401094 (2002).
    • (2002) Cell Death and Differentiation , vol.9 , pp. 1172-1184
    • Nie, Z.1
  • 7
    • 78049408241 scopus 로고    scopus 로고
    • Fusion-active glycoprotein G mediates the cytotoxicity of vesicular stomatitis virus M mutants lacking host shut-off activity
    • Hoffmann, M. et al. Fusion-active glycoprotein G mediates the cytotoxicity of vesicular stomatitis virus M mutants lacking host shut-off activity. The Journal of general virology 91, 2782-2793, doi:10.1099/vir.0.023978-0 (2010).
    • (2010) The Journal of General Virology , vol.91 , pp. 2782-2793
    • Hoffmann, M.1
  • 8
    • 77956928344 scopus 로고    scopus 로고
    • Transfusion independence and HMGA2 activation after gene therapy of human beta-thalassaemia
    • Cavazzana-Calvo, M. et al. Transfusion independence and HMGA2 activation after gene therapy of human beta-thalassaemia. Nature 467, 318-322, doi:10.1038/nature09328 (2010).
    • (2010) Nature , vol.467 , pp. 318-322
    • Cavazzana-Calvo, M.1
  • 9
    • 70449427834 scopus 로고    scopus 로고
    • Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
    • Cartier, N. et al. Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. Science 326, 818-823, doi:10.1126/science.1171242 (2009).
    • (2009) Science , vol.326 , pp. 818-823
    • Cartier, N.1
  • 10
    • 84879873039 scopus 로고    scopus 로고
    • Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy
    • Biffi, A. et al. Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy. Science, doi:10.1126/science.1233158 (2013).
    • (2013) Science
    • Biffi, A.1
  • 11
    • 84879867061 scopus 로고    scopus 로고
    • Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome
    • Aiuti, A. et al. Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome. Science, doi:10.1126/science.1233151 (2013).
    • (2013) Science
    • Aiuti, A.1
  • 12
    • 84876475656 scopus 로고    scopus 로고
    • Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV
    • Tebas, P. et al. Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV. Blood 121, 1524-1533, doi:10.1182/blood-2012-07-447250 (2013).
    • (2013) Blood , vol.121 , pp. 1524-1533
    • Tebas, P.1
  • 13
    • 80051775476 scopus 로고    scopus 로고
    • T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
    • Kalos, M. et al. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Science translational medicine 3, 95ra73, doi:10.1126/scitranslmed.3002842 (2011).
    • (2011) Science Translational Medicine , vol.3 , pp. 95ra73
    • Kalos, M.1
  • 15
    • 33846081072 scopus 로고    scopus 로고
    • Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9
    • Pichlmair, A. et al. Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9. J Virol 81, 539-547, doi:10.1128/jvi.01818-06 (2007).
    • (2007) J Virol , vol.81 , pp. 539-547
    • Pichlmair, A.1
  • 16
    • 67149117119 scopus 로고    scopus 로고
    • Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection
    • Throm, R. E. et al. Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection. Blood 113, 5104-5110, doi:10.1182/blood-2008-11-191049 (2009).
    • (2009) Blood , vol.113 , pp. 5104-5110
    • Throm, R.E.1
  • 17
    • 84878746232 scopus 로고    scopus 로고
    • Transduction of human CD34+ repopulating cells with a self-inactivating lentiviral vector for SCID-X1 produced at clinical scale by a stable cell line
    • Greene, M. R. et al. Transduction of human CD34+ repopulating cells with a self-inactivating lentiviral vector for SCID-X1 produced at clinical scale by a stable cell line. Human gene therapy methods 23, 297-308, doi:10.1089/hgtb.2012.150 (2012).
    • (2012) Human Gene Therapy Methods , vol.23 , pp. 297-308
    • Greene, M.R.1
  • 18
    • 67349240866 scopus 로고    scopus 로고
    • Development of inducible EIAV-based lentiviral vector packaging and producer cell lines
    • Stewart, H. J., Leroux-Carlucci, M. A., Sion, C. J., Mitrophanous, K. A. & Radcliffe, P. A. Development of inducible EIAV-based lentiviral vector packaging and producer cell lines. Gene Ther 16, 805-814, doi:10.1038/gt.2009.20 (2009).
    • (2009) Gene Ther , vol.16 , pp. 805-814
    • Stewart, H.J.1    Leroux-Carlucci, M.A.2    Sion, C.J.3    Mitrophanous, K.A.4    Radcliffe, P.A.5
  • 19
    • 79952686685 scopus 로고    scopus 로고
    • A stable producer cell line for the manufacture of a lentiviral vector for gene therapy of Parkinson's disease
    • Stewart, H. J. et al. A stable producer cell line for the manufacture of a lentiviral vector for gene therapy of Parkinson's disease. Hum Gene Ther 22, 357-369, doi:10.1089/hum.2010.142 (2011).
    • (2011) Hum Gene Ther , vol.22 , pp. 357-369
    • Stewart, H.J.1
  • 20
    • 21044453936 scopus 로고    scopus 로고
    • Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector
    • Ni, Y. et al. Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector. J Gene Med 7, 818-834, doi:10.1002/jgm.726 (2005).
    • (2005) J Gene Med , vol.7 , pp. 818-834
    • Ni, Y.1
  • 21
    • 39849094316 scopus 로고    scopus 로고
    • Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture
    • Broussau, S. et al. Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture. Mol Ther 16, 500-507, doi:10.1038/sj.mt.6300383 (2008).
    • (2008) Mol Ther , vol.16 , pp. 500-507
    • Broussau, S.1
  • 22
    • 0034914353 scopus 로고    scopus 로고
    • A new-generation stable inducible packaging cell line for lentiviral vectors
    • Farson, D. et al. A new-generation stable inducible packaging cell line for lentiviral vectors. Hum Gene Ther 12, 981-997, doi:10.1089/104303401750195935 (2001).
    • (2001) Hum Gene Ther , vol.12 , pp. 981-997
    • Farson, D.1
  • 23
    • 0038333587 scopus 로고    scopus 로고
    • Continuous high-titer HIV-1 vector production
    • Ikeda, Y. et al. Continuous high-titer HIV-1 vector production. Nat Biotechnol 21, 569-572, doi:10.1038/nbt815 (2003).
    • (2003) Nat Biotechnol , vol.21 , pp. 569-572
    • Ikeda, Y.1
  • 24
    • 14044263641 scopus 로고    scopus 로고
    • Gene transfer to repopulating human CD34+ cells using amphotropic-, GALV-, or RD114-pseudotyped HIV-1-based vectors from stable producer cells
    • Relander, T. et al. Gene transfer to repopulating human CD34+ cells using amphotropic-, GALV-, or RD114-pseudotyped HIV-1-based vectors from stable producer cells. Mol Ther 11, 452-459, doi:10.1016/j.ymthe.2004.10.014 (2005).
    • (2005) Mol Ther , vol.11 , pp. 452-459
    • Relander, T.1
  • 25
    • 0036682935 scopus 로고    scopus 로고
    • Lentiviral vectors pseudotyped with amodified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates
    • Sandrin, V. et al. Lentiviral vectors pseudotyped with amodified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates. Blood 100, 823-832, doi:10.1182/blood-2001-11-0042 (2002).
    • (2002) Blood , vol.100 , pp. 823-832
    • Sandrin, V.1
  • 26
    • 0141889328 scopus 로고    scopus 로고
    • Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD341 cells
    • Brenner, S. et al. Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD341 cells. Blood 102, 2789-2797, doi:10.1182/blood-2002-05-1482 (2003).
    • (2003) Blood , vol.102 , pp. 2789-2797
    • Brenner, S.1
  • 27
    • 84883002841 scopus 로고    scopus 로고
    • RD2-MolPack-Chim3, a packaging cell line for stable production of lentiviral vectors for anti-HIV gene therapy
    • Stornaiuolo, A. et al. RD2-MolPack-Chim3, a packaging cell line for stable production of lentiviral vectors for anti-HIV gene therapy. Human gene therapy methods, doi:10.1089/hgtb.2012.190 (2013).
    • (2013) Human Gene Therapy Methods
    • Stornaiuolo, A.1
  • 29
    • 0030809406 scopus 로고    scopus 로고
    • Targeted integration of DNA using mutant lox sites in embryonic stem cells
    • Araki, K., Araki, M. & Yamamura, K. Targeted integration of DNA using mutant lox sites in embryonic stem cells. Nucleic Acids Res 25, 868-872 (1997).
    • (1997) Nucleic Acids Res , vol.25 , pp. 868-872
    • Araki, K.1    Araki, M.2    Yamamura, K.3
  • 31
    • 6344228445 scopus 로고    scopus 로고
    • Influence of gag on human immunodeficiency virus type 1 species-specific tropism
    • Ikeda, Y., Ylinen, L. M., Kahar-Bador, M. & Towers, G. J. Influence of gag on human immunodeficiency virus type 1 species-specific tropism. J Virol 78, 11816-11822 (2004).
    • (2004) J Virol , vol.78 , pp. 11816-11822
    • Ikeda, Y.1    Ylinen, L.M.2    Kahar-Bador, M.3    Towers, G.J.4
  • 32
    • 28844479566 scopus 로고    scopus 로고
    • Naturally occurring capsid substitutions render HIV-1 cyclophilin Aindependent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells
    • Chatterji, U. et al. Naturally occurring capsid substitutions render HIV-1 cyclophilin Aindependent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells. J Biol Chem 280, 40293-40300 (2005).
    • (2005) J Biol Chem , vol.280 , pp. 40293-40300
    • Chatterji, U.1
  • 33
    • 34648840100 scopus 로고    scopus 로고
    • The presence of the Trim5alpha escape mutation H87Q in the capsid of late stage HIV-1 variants is preceded by a prolonged asymptomatic infection phase
    • Kootstra, N. A., Navis, M., Beugeling, C., van Dort, K. A. & Schuitemaker, H. The presence of the Trim5alpha escape mutation H87Q in the capsid of late stage HIV-1 variants is preceded by a prolonged asymptomatic infection phase. Aids 21, 2015-2023, doi:10.1097/QAD.0b013e3282effa87 (2007).
    • (2007) Aids , vol.21 , pp. 2015-2023
    • Kootstra, N.A.1    Navis, M.2    Beugeling, C.3    Van Dort, K.A.4    Schuitemaker, H.5
  • 34
    • 0031743608 scopus 로고    scopus 로고
    • Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
    • Zufferey, R. et al. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 72, 9873-9880 (1998).
    • (1998) J Virol , vol.72 , pp. 9873-9880
    • Zufferey, R.1
  • 35
    • 65249101260 scopus 로고    scopus 로고
    • The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
    • Montini, E. et al. The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy. The Journal of clinical investigation 119, 964-975, doi:10.1172/jci37630 (2009).
    • (2009) The Journal of Clinical Investigation , vol.119 , pp. 964-975
    • Montini, E.1
  • 36
    • 70449127230 scopus 로고    scopus 로고
    • Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors
    • Modlich, U. et al. Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors. Mol Ther 17, 1919-1928, doi:10.1038/mt.2009.179 (2009).
    • (2009) Mol Ther , vol.17 , pp. 1919-1928
    • Modlich, U.1
  • 37
    • 0033780046 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
    • O'Doherty, U., Swiggard, W. J. & Malim, M. H. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding. J Virol 74, 10074-10080 (2000).
    • (2000) J Virol , vol.74 , pp. 10074-10080
    • O'Doherty, U.1    Swiggard, W.J.2    Malim, M.H.3
  • 38
    • 1842429029 scopus 로고    scopus 로고
    • Characterization of HIV-1 vectors with gammaretrovirus envelope glycoproteins produced from stable packaging cells
    • Strang, B. L., Ikeda, Y., Cosset, F. L., Collins, M. K. & Takeuchi, Y. Characterization of HIV-1 vectors with gammaretrovirus envelope glycoproteins produced from stable packaging cells. Gene Ther 11, 591-598, doi:10.1038/sj.gt.3302189 (2004).
    • (2004) Gene Ther , vol.11 , pp. 591-598
    • Strang, B.L.1    Ikeda, Y.2    Cosset, F.L.3    Collins, M.K.4    Takeuchi, Y.5
  • 39
    • 77957825561 scopus 로고    scopus 로고
    • RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectors
    • Bell, A. J., Jr., Fegen, D., Ward, M. & Bank, A. RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectors. Exp Biol Med (Maywood) 235, 1269-1276, doi:10.1258/ebm.2010.010053 (2010).
    • (2010) Exp Biol Med (Maywood) , vol.235 , pp. 1269-1276
    • Bell, A.J.1    Fegen, D.2    Ward, M.3    Bank, A.4
  • 41
    • 0037043699 scopus 로고    scopus 로고
    • Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
    • Sheehy, A. M., Gaddis, N. C., Choi, J. D. & Malim, M. H. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 418, 646-650, doi:10.1038/nature00939 (2002).
    • (2002) Nature , vol.418 , pp. 646-650
    • Sheehy, A.M.1    Gaddis, N.C.2    Choi, J.D.3    Malim, M.H.4
  • 42
    • 79955939275 scopus 로고    scopus 로고
    • APOBEC3-mediated hypermutation of retroviral vectors produced from some retrovirus packaging cell lines
    • Miller, A. D. & Metzger, M. J. APOBEC3-mediated hypermutation of retroviral vectors produced from some retrovirus packaging cell lines. Gene Ther 18, 528-530, doi:10.1038/gt.2010.177 (2011).
    • (2011) Gene Ther , vol.18 , pp. 528-530
    • Miller, A.D.1    Metzger, M.J.2
  • 43
    • 34250688401 scopus 로고    scopus 로고
    • All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition
    • Kinomoto, M. et al. All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition. Nucleic Acids Res 35, 2955-2964, doi:10.1093/nar/gkm181 (2007).
    • (2007) Nucleic Acids Res , vol.35 , pp. 2955-2964
    • Kinomoto, M.1
  • 44
    • 84879883823 scopus 로고    scopus 로고
    • Gene therapy for PIDs: Progress, pitfalls and prospects
    • Mukherjee, S. & Thrasher, A. J. Gene therapy for PIDs: Progress, pitfalls and prospects. Gene, doi:10.1016/j.gene.2013.03.098 (2013).
    • (2013) Gene
    • Mukherjee, S.1    Thrasher, A.J.2
  • 45
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • Zufferey, R., Nagy, D., Mandel, R. J., Naldini, L. & Trono, D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol 15, 871-875, doi:10.1038/nbt0997-871 (1997).
    • (1997) Nat Biotechnol , vol.15 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4    Trono, D.5
  • 46
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini, L. et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267 (1996).
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1
  • 47
    • 0026566559 scopus 로고
    • DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood
    • Bergsagel, D. J., Finegold, M. J., Butel, J. S., Kupsky, W. J. & Garcea, R. L. DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood. The New England journal of medicine 326, 988-993, doi:10.1056/nejm199204093261504 (1992).
    • (1992) The New England Journal of Medicine , vol.326 , pp. 988-993
    • Bergsagel, D.J.1    Finegold, M.J.2    Butel, J.S.3    Kupsky, W.J.4    Garcea, R.L.5
  • 48
    • 1142309492 scopus 로고    scopus 로고
    • Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment
    • Sastry, L., Xu, Y., Cooper, R., Pollok, K. & Cornetta, K. Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment. Hum Gene Ther 15, 221-226, doi:10.1089/104303404772680029 (2004).
    • (2004) Hum Gene Ther , vol.15 , pp. 221-226
    • Sastry, L.1    Xu, Y.2    Cooper, R.3    Pollok, K.4    Cornetta, K.5


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