메뉴 건너뛰기




Volumn 56, Issue 3, 2015, Pages 1719-1732

In vivo role of TLR2 and MyD88 signaling in eliciting innate immune responses in staphylococcal endophthalmitis

Author keywords

CRAMP; Endophthalmitis; Inflammation; MyD88; Retinal damage; Staphylococcus aureus; TLR2

Indexed keywords

CHEMOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; POLYPEPTIDE ANTIBIOTIC AGENT; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE; CYTOKINE; MYD88 PROTEIN, MOUSE; TLR2 PROTEIN, MOUSE;

EID: 84924529735     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.14-16087     Document Type: Article
Times cited : (46)

References (52)
  • 1
    • 77953460085 scopus 로고    scopus 로고
    • Endophthalmitis: Pathogenesis, clinical presentation, management, and perspectives
    • Kernt M, Kampik A. Endophthalmitis: pathogenesis, clinical presentation, management, and perspectives. Clin Ophthal-mol. 2010;4:121-135.
    • (2010) Clin Ophthal-Mol , vol.4 , pp. 121-135
    • Kernt, M.1    Kampik, A.2
  • 2
    • 75649084602 scopus 로고    scopus 로고
    • Toll-like receptor 2 ligand-induced protection against bacterial endoph-thalmitis
    • Kumar A, Singh CN, Glybina IV, Mahmoud TH, Yu FS. Toll-like receptor 2 ligand-induced protection against bacterial endoph-thalmitis. J Infect Dis. 2010;201:255-263.
    • (2010) J Infect Dis , vol.201 , pp. 255-263
    • Kumar, A.1    Singh, C.N.2    Glybina, I.V.3    Mahmoud, T.H.4    Yu, F.S.5
  • 3
    • 79959546869 scopus 로고    scopus 로고
    • TLR2 mediates the innate response of retinal Muller glia to Staphylococcus aureus
    • Shamsuddin N, Kumar A. TLR2 mediates the innate response of retinal Muller glia to Staphylococcus aureus. J Immunol. 2011;186:7089-7097.
    • (2011) J Immunol , vol.186 , pp. 7089-7097
    • Shamsuddin, N.1    Kumar, A.2
  • 4
    • 42149127827 scopus 로고    scopus 로고
    • AlphaB-crystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis
    • Whiston EA, Sugi N, Kamradt MC, et al. alphaB-crystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis. Infect Immun. 2008;76:1781-1790.
    • (2008) Infect Immun , vol.76 , pp. 1781-1790
    • Whiston, E.A.1    Sugi, N.2    Kamradt, M.C.3
  • 5
    • 33846808899 scopus 로고    scopus 로고
    • Bacterial endoph-thalmitis: Therapeutic challenges and host-pathogen interac- tions
    • Callegan M, Gilmore M, Gregory M, et al. Bacterial endoph-thalmitis: therapeutic challenges and host-pathogen interac- tions. Prog Retin Eye Res. 2007;26:189-203.
    • (2007) Prog Retin Eye Res , vol.26 , pp. 189-203
    • Callegan, M.1    Gilmore, M.2    Gregory, M.3
  • 6
    • 77957917480 scopus 로고    scopus 로고
    • Severe bacterial endophthalmitis: Towards improving clinical outcomes
    • Novosad BD, Callegan MC. Severe bacterial endophthalmitis: towards improving clinical outcomes. Expert Rev Ophthal-mol. 2010;5:689-698.
    • (2010) Expert Rev Ophthal-Mol , vol.5 , pp. 689-698
    • Novosad, B.D.1    Callegan, M.C.2
  • 7
    • 84861459508 scopus 로고    scopus 로고
    • Bacterial endophthalmitis in the age of outpatient intravitreal therapies and cataract surgeries: Host-microbe interactions in intraocular infection
    • Sadaka A, Durand M, Gilmore M. Bacterial endophthalmitis in the age of outpatient intravitreal therapies and cataract surgeries: host-microbe interactions in intraocular infection. Prog Retin Eye Res. 2012;31:316-331.
    • (2012) Prog Retin Eye Res , vol.31 , pp. 316-331
    • Sadaka, A.1    Durand, M.2    Gilmore, M.3
  • 8
    • 5644249574 scopus 로고    scopus 로고
    • Update of the management of postoper- ative endophthalmitis
    • Yam JC, Kwok AK. Update of the management of postoper- ative endophthalmitis. Hong Kong Med J. 2004;10:337-343.
    • (2004) Hong Kong Med J , vol.10 , pp. 337-343
    • Yam, J.C.1    Kwok, A.K.2
  • 9
    • 77955589135 scopus 로고    scopus 로고
    • Emerging antibiotic resistance in ocular infections and the role of fluoroquinolones
    • McDonald M, Blondeau JM. Emerging antibiotic resistance in ocular infections and the role of fluoroquinolones. J Cataract Refract Surg. 2010;36:1588-1598.
    • (2010) J Cataract Refract Surg , vol.36 , pp. 1588-1598
    • McDonald, M.1    Blondeau, J.M.2
  • 10
    • 84901844737 scopus 로고    scopus 로고
    • Virulence properties of multidrug resistant ocular isolates of Acineto-bacter baumannii
    • Talreja D, Muraleedharan C, Gunathilaka G, et al. Virulence properties of multidrug resistant ocular isolates of Acineto-bacter baumannii. Curr Eye Res. 2014;39:695-704.
    • (2014) Curr Eye Res , vol.39 , pp. 695-704
    • Talreja, D.1    Muraleedharan, C.2    Gunathilaka, G.3
  • 11
    • 73549111770 scopus 로고    scopus 로고
    • Staphylococcus aureus endophthalmitis: Antibiotic susceptibilities, methicillin resistance, and clinical outcomes
    • Major JC Jr, Engelbert M, Flynn HW Jr, Miller D, Smiddy WE, Davis JL. Staphylococcus aureus endophthalmitis: antibiotic susceptibilities, methicillin resistance, and clinical outcomes. Am J Ophthalmol. 2010;149:278-283.
    • (2010) Am J Ophthalmol , vol.149 , pp. 278-283
    • Major, J.C.1    Engelbert, M.2    Flynn, H.W.3    Miller, D.4    Smiddy, W.E.5    Davis, J.L.6
  • 12
    • 78650701468 scopus 로고    scopus 로고
    • Methicillin resistance of Staphylococcus species among health care and nonhealth care workers undergoing cataract surgery
    • Olson R, Donnenfeld E, Bucci FA Jr, et al. Methicillin resistance of Staphylococcus species among health care and nonhealth care workers undergoing cataract surgery. Clin Ophthalmol. 2010;4:1505-1514.
    • (2010) Clin Ophthalmol , vol.4 , pp. 1505-1514
    • Olson, R.1    Donnenfeld, E.2    Bucci, F.A.3
  • 13
    • 84879571880 scopus 로고    scopus 로고
    • Staphylococcus aureus corneal infections: Effect of the Panton-Valentine leukocidin (PVL) and antibody to PVL on virulence and pathology
    • Zaidi T, Yoong P, Pier GB. Staphylococcus aureus corneal infections: effect of the Panton-Valentine leukocidin (PVL) and antibody to PVL on virulence and pathology. Invest Ophthal- mol Vis Sci. 2013;54:4430-4438.
    • (2013) Invest Ophthal- Mol Vis Sci , vol.54 , pp. 4430-4438
    • Zaidi, T.1    Yoong, P.2    Pier, G.B.3
  • 14
    • 39149140368 scopus 로고    scopus 로고
    • Visual outcome and bacterial sensitivity after methicillin-resistant Staphylo-coccus aureus-associated acute endophthalmitis
    • Deramo VA, Lai JC, Winokur J, Luchs J, Udell IJ. Visual outcome and bacterial sensitivity after methicillin-resistant Staphylo-coccus aureus-associated acute endophthalmitis. Am J Oph- thalmol. 2008;145:413-417.
    • (2008) Am J Oph- Thalmol , vol.145 , pp. 413-417
    • Deramo, V.A.1    Lai, J.C.2    Winokur, J.3    Luchs, J.4    Udell, I.J.5
  • 15
    • 0036142980 scopus 로고    scopus 로고
    • Bacterial endophthalmitis: Epidemiology, therapeutics, and bacterium-host interactions
    • Callegan MC, Engelbert M, Parke DW II, Jett BD, Gilmore MS. Bacterial endophthalmitis: epidemiology, therapeutics, and bacterium-host interactions. Clin Microbiol Rev. 2002;15:111-124.
    • (2002) Clin Microbiol Rev , vol.15 , pp. 111-124
    • Callegan, M.C.1    Engelbert, M.2    Parke, D.3    Jett, B.D.4    Gilmore, M.S.5
  • 16
    • 0036377910 scopus 로고    scopus 로고
    • Immunology of staphylococcal biofilm infections in the eye: New tools to study biofilm endophthalmitis
    • Leid JG, Costerton JW, Shirtliff ME, Gilmore MS, Engelbert M. Immunology of staphylococcal biofilm infections in the eye: new tools to study biofilm endophthalmitis. DNA Cell Biol. 2002;21:405-413.
    • (2002) DNA Cell Biol , vol.21 , pp. 405-413
    • Leid, J.G.1    Costerton, J.W.2    Shirtliff, M.E.3    Gilmore, M.S.4    Engelbert, M.5
  • 17
    • 84877807508 scopus 로고    scopus 로고
    • Increased resistance to Staphylococcus aureus endophthalmitis in BALB/c mice: Fas ligand is required for resolution of inflammation but not for bacterial clearance
    • Sugi N, Whiston EA, Ksander BR, Gregory MS. Increased resistance to Staphylococcus aureus endophthalmitis in BALB/c mice: Fas ligand is required for resolution of inflammation but not for bacterial clearance. Infect Immun. 2013;81:2217-2225.
    • (2013) Infect Immun , vol.81 , pp. 2217-2225
    • Sugi, N.1    Whiston, E.A.2    Ksander, B.R.3    Gregory, M.S.4
  • 19
    • 85047688666 scopus 로고    scopus 로고
    • Toll-like receptor 2 ligand pretreatment attenuates retinal microglial inflammatory re-sponse but enhances phagocytic activity toward Staphylococ- cus aureus
    • Kochan T, Singla A, Tosi J, Kumar A. Toll-like receptor 2 ligand pretreatment attenuates retinal microglial inflammatory re-sponse but enhances phagocytic activity toward Staphylococ- cus aureus. Infect Immun. 2012;80:2076-2088.
    • (2012) Infect Immun , vol.80 , pp. 2076-2088
    • Kochan, T.1    Singla, A.2    Tosi, J.3    Kumar, A.4
  • 20
    • 84875939928 scopus 로고    scopus 로고
    • Muller glia in retinal innate immunity: A perspective on their roles in endophthalmitis
    • Kumar A, Pandey RK, Miller LJ, Singh PK, Kanwar M. Muller glia in retinal innate immunity: a perspective on their roles in endophthalmitis. Crit Rev Immunol. 2013;33:119-135.
    • (2013) Crit Rev Immunol , vol.33 , pp. 119-135
    • Kumar, A.1    Pandey, R.K.2    Miller, L.J.3    Singh, P.K.4    Kanwar, M.5
  • 21
    • 84891702527 scopus 로고    scopus 로고
    • Targeting toll-like receptor signaling as a novel approach to prevent ocular infectious diseases
    • Pandey RK, Yu FS, Kumar A. Targeting toll-like receptor signaling as a novel approach to prevent ocular infectious diseases. Indian J Med Res. 2013;138:609-619.
    • (2013) Indian J Med Res , vol.138 , pp. 609-619
    • Pandey, R.K.1    Yu, F.S.2    Kumar, A.3
  • 22
    • 84855489606 scopus 로고    scopus 로고
    • Retinal Muller glia initiate innate response to infectious stimuli via Toll-like receptor signaling
    • Kumar A, Shamsuddin N. Retinal Muller glia initiate innate response to infectious stimuli via Toll-like receptor signaling. PLoS One. 2012;7:e29830.
    • (2012) Plos One , vol.7
    • Kumar, A.1    Shamsuddin, N.2
  • 23
    • 84896389865 scopus 로고    scopus 로고
    • Antibacterial responses of retinal Müller glia: Production of antimicrobial peptides, oxidative burst and phagocytosis
    • Singh P, Shiha M, Kumar A. Antibacterial responses of retinal Müller glia: production of antimicrobial peptides, oxidative burst and phagocytosis. J Neuroinflammation. 2014;11:33.
    • (2014) J Neuroinflammation , vol.11 , pp. 33
    • Singh, P.1    Shiha, M.2    Kumar, A.3
  • 24
    • 84856868606 scopus 로고    scopus 로고
    • Staphylococcus aureus isolated from endophthalmitis are hospital-acquired based on Panton-Valentine leukocidin and antibiotic susceptibility testing
    • Rarey KA, Shanks RM, Romanowski EG, Mah FS, Kowalski RP. Staphylococcus aureus isolated from endophthalmitis are hospital-acquired based on Panton-Valentine leukocidin and antibiotic susceptibility testing. J Ocul Pharmacol Ther. 2012; 28:12-16.
    • (2012) J Ocul Pharmacol Ther , vol.28 , pp. 12-16
    • Rarey, K.A.1    Shanks, R.M.2    Romanowski, E.G.3    Mah, F.S.4    Kowalski, R.P.5
  • 25
    • 33751187318 scopus 로고    scopus 로고
    • Acute inflammation and loss of retinal architecture and function during experimental Bacillus endophthalmitis
    • Ramadan RT, Ramirez R, Novosad BD, Callegan MC. Acute inflammation and loss of retinal architecture and function during experimental Bacillus endophthalmitis. Curr Eye Res. 2006;31:955-965.
    • (2006) Curr Eye Res , vol.31 , pp. 955-965
    • Ramadan, R.T.1    Ramirez, R.2    Novosad, B.D.3    Callegan, M.C.4
  • 26
    • 84898918728 scopus 로고    scopus 로고
    • Pathogenicity of ocular isolates of Acinetobacter baumannii in a mouse model of bacterial endophthalmitis
    • Talreja D, Kaye KS, Yu FS, Walia SK, Kumar A. Pathogenicity of ocular isolates of Acinetobacter baumannii in a mouse model of bacterial endophthalmitis. Invest Ophthalmol Vis Sci. 2014; 55:2392-2402.
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , pp. 2392-2402
    • Talreja, D.1    Kaye, K.S.2    Yu, F.S.3    Walia, S.K.4    Kumar, A.5
  • 27
    • 84905403715 scopus 로고    scopus 로고
    • Intravitreal injection of the chimeric phage endolysin Ply187 protects mice from Staph-ylococcus aureus endophthalmitis
    • Singh PK, Donovan DM, Kumar A. Intravitreal injection of the chimeric phage endolysin Ply187 protects mice from Staph-ylococcus aureus endophthalmitis. Antimicrob Agents Che- mother. 2014;58:4621-4629.
    • (2014) Antimicrob Agents Che- Mother , vol.58 , pp. 4621-4629
    • Singh, P.K.1    Donovan, D.M.2    Kumar, A.3
  • 28
    • 23244444708 scopus 로고    scopus 로고
    • Gilmore MS. Fas ligand but not complement is critical for control of experimental Staphylococcus aureus Endophthalmitis
    • Engelbert M, Gilmore MS. Fas ligand but not complement is critical for control of experimental Staphylococcus aureus Endophthalmitis. Invest Ophthalmol Vis Sci. 2005;46:2479-2486.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 2479-2486
    • Engelbert, M.1
  • 29
    • 82755187031 scopus 로고    scopus 로고
    • Role of Toll-like receptor (TLR) 2 in experimental Bacillus cereus endophthalmitis
    • Novosad BD, Astley RA, Callegan MC. Role of Toll-like receptor (TLR) 2 in experimental Bacillus cereus endophthalmitis. PLoS One. 2011;6:e28619.
    • (2011) Plos One , vol.6
    • Novosad, B.D.1    Astley, R.A.2    Callegan, M.C.3
  • 30
    • 84903534092 scopus 로고    scopus 로고
    • Role of TLR5 and flagella in bacillus intraocular infection
    • Parkunan SM, Astley R, Callegan MC. Role of TLR5 and flagella in bacillus intraocular infection. PLoS One. 2014;9:e100543.
    • (2014) Plos One , vol.9
    • Parkunan, S.M.1    Astley, R.2    Callegan, M.C.3
  • 31
    • 37749037714 scopus 로고    scopus 로고
    • Flagellin suppresses the inflammatory response and enhances bacterial clearance in a murine model of Pseudomonas aeruginosa keratitis
    • Kumar A, Hazlett LD, Yu FS. Flagellin suppresses the inflammatory response and enhances bacterial clearance in a murine model of Pseudomonas aeruginosa keratitis. Infect Immun. 2008;76:89-96.
    • (2008) Infect Immun , vol.76 , pp. 89-96
    • Kumar, A.1    Hazlett, L.D.2    Yu, F.S.3
  • 32
    • 33748077451 scopus 로고    scopus 로고
    • Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88
    • Sun Y, Hise AG, Kalsow CM, Pearlman E. Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88. Infect Immun. 2006;74:5325-5332.
    • (2006) Infect Immun , vol.74 , pp. 5325-5332
    • Sun, Y.1    Hise, A.G.2    Kalsow, C.M.3    Pearlman, E.4
  • 33
    • 84904348543 scopus 로고    scopus 로고
    • TLR4 Contributes to the host response to Klebsiella intraocular infection
    • Hunt JJ, Astley R, Wheatley N, Wang JT, Callegan MC. TLR4 Contributes to the host response to Klebsiella intraocular infection. Curr Eye Res. 2014;39:790-802.
    • (2014) Curr Eye Res , vol.39 , pp. 790-802
    • Hunt, J.J.1    Astley, R.2    Wheatley, N.3    Wang, J.T.4    Callegan, M.C.5
  • 35
    • 79960132943 scopus 로고    scopus 로고
    • Cytokine release from innate immune cells: Association with diverse membrane trafficking pathways
    • Lacy P, Stow JL. Cytokine release from innate immune cells: association with diverse membrane trafficking pathways. Blood. 2011;118:9-18.
    • (2011) Blood , vol.118 , pp. 9-18
    • Lacy, P.1    Stow, J.L.2
  • 36
    • 0038238035 scopus 로고    scopus 로고
    • Mitigation of neutrophil infiltration in a rat model of early Staphylococcus aureus endophthalmitis
    • Giese MJ, Rayner SA, Fardin B, et al. Mitigation of neutrophil infiltration in a rat model of early Staphylococcus aureus endophthalmitis. Invest Ophthalmol Vis Sci. 2003;44:3077-3082.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3077-3082
    • Giese, M.J.1    Rayner, S.A.2    Fardin, B.3
  • 37
    • 84884135406 scopus 로고    scopus 로고
    • Contribution of Toll-like receptor 2 to the innate response against Staphylococcus aureus infection in mice
    • Yimin, Kohanawa M, Zhao S, et al. Contribution of Toll-like receptor 2 to the innate response against Staphylococcus aureus infection in mice. PLoS One. 2013;8:e74287.
    • (2013) Plos One , vol.8
    • Yimin, K.M.1    Zhao, S.2
  • 38
    • 0034669910 scopus 로고    scopus 로고
    • Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylo- coccus aureus infection
    • Takeuchi O, Hoshino K, Akira S. Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylo- coccus aureus infection. J Immunol. 2000;165:5392-5396.
    • (2000) J Immunol , vol.165 , pp. 5392-5396
    • Takeuchi, O.1    Hoshino, K.2    Akira, S.3
  • 40
    • 84901844737 scopus 로고    scopus 로고
    • Virulence properties of multidrug resistant ocular isolates of Acineto-bacter baumannii
    • Talreja D, Muraleedharan C, Gunathilaka G, et al. Virulence properties of multidrug resistant ocular isolates of Acineto-bacter baumannii. Curr Eye Res. 2014;39:695-704.
    • (2014) Curr Eye Res , vol.39 , pp. 695-704
    • Talreja, D.1    Muraleedharan, C.2    Gunathilaka, G.3
  • 41
    • 42049086745 scopus 로고    scopus 로고
    • Staphylococcus aureus lipoproteins trigger human corneal epithelial innate response through toll-like receptor-2
    • Li Q, Kumar A, Gui JF, Yu FS. Staphylococcus aureus lipoproteins trigger human corneal epithelial innate response through toll-like receptor-2. Microb Pathog. 2008;44:426-434.
    • (2008) Microb Pathog , vol.44 , pp. 426-434
    • Li, Q.1    Kumar, A.2    Gui, J.F.3    Yu, F.S.4
  • 42
    • 81355142848 scopus 로고    scopus 로고
    • Toll-like receptors (TLRs) in innate immune defense against Staphylococcus aureus
    • Pietrocola G, Arciola CR, Rindi S, et al. Toll-like receptors (TLRs) in innate immune defense against Staphylococcus aureus. Int J Artif Organs. 2011;34:799-810.
    • (2011) Int J Artif Organs , vol.34 , pp. 799-810
    • Pietrocola, G.1    Arciola, C.R.2    Rindi, S.3
  • 43
    • 0742324860 scopus 로고    scopus 로고
    • TLR signaling pathways
    • Takeda K, Akira S. TLR signaling pathways. Semin Immunol. 2004;16:3-9.
    • (2004) Semin Immunol , vol.16 , pp. 3-9
    • Takeda, K.1    Akira, S.2
  • 44
    • 79960845616 scopus 로고    scopus 로고
    • Immunity against Staphylococcus aureus cutaneous infections
    • Miller LS, Cho JS. Immunity against Staphylococcus aureus cutaneous infections. Nat Rev Immunol. 2011;11:505-518.
    • (2011) Nat Rev Immunol , vol.11 , pp. 505-518
    • Miller, L.S.1    Cho, J.S.2
  • 45
    • 84871839728 scopus 로고    scopus 로고
    • MyD88: A critical adaptor protein in innate immunity signal transduction
    • Warner N, Núñez G. MyD88: a critical adaptor protein in innate immunity signal transduction. J Immunol. 2013;190:3-4.
    • (2013) J Immunol , vol.190 , pp. 3-4
    • Warner, N.1    Núñez, G.2
  • 46
    • 77958105033 scopus 로고    scopus 로고
    • Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection
    • Kumar A, Gao N, Standiford TJ, Gallo RL, Yu FS. Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection. Microbes Infect. 2010;12:978-989.
    • (2010) Microbes Infect , vol.12 , pp. 978-989
    • Kumar, A.1    Gao, N.2    Standiford, T.J.3    Gallo, R.L.4    Yu, F.S.5
  • 47
    • 35748985576 scopus 로고    scopus 로고
    • Cathelicidin-deficient (Cnlp/) mice show increased susceptibility to Pseudomonas aeruginosa keratitis
    • Huang LC, Reins RY, Gallo RL, McDermott AM. Cathelicidin-deficient (Cnlp/) mice show increased susceptibility to Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci. 2007;48:4498-4508.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 4498-4508
    • Huang, L.C.1    Reins, R.Y.2    Gallo, R.L.3    McDermott, A.M.4
  • 48
    • 80655147145 scopus 로고    scopus 로고
    • Cathelicidin peptide LL-37 modulates TREM-1 expression and inflammatory responses to microbial compounds
    • Amatngalim GD, Nijnik A, Hiemstra PS, Hancock RE. Cathelicidin peptide LL-37 modulates TREM-1 expression and inflammatory responses to microbial compounds. In- flammation. 2011;34:412-425.
    • (2011) In- Flammation , vol.34 , pp. 412-425
    • Amatngalim, G.D.1    Nijnik, A.2    Hiemstra, P.S.3    Hancock, R.E.4
  • 49
    • 18644363054 scopus 로고    scopus 로고
    • Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant
    • Kurosaka K, Chen Q, Yarovinsky F, Oppenheim JJ, Yang D. Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant. J Immunol. 2005;174:6257-6265.
    • (2005) J Immunol , vol.174 , pp. 6257-6265
    • Kurosaka, K.1    Chen, Q.2    Yarovinsky, F.3    Oppenheim, J.J.4    Yang, D.5
  • 51
    • 77951044334 scopus 로고    scopus 로고
    • The antimicrobial peptide LL-37 modulates the inflammatory and host defense response of human neutrophils
    • Alalwani SM, Sierigk J, Herr C, et al. The antimicrobial peptide LL-37 modulates the inflammatory and host defense response of human neutrophils. Eur J Immunol. 2010;40: 1118-1126.
    • (2010) Eur J Immunol , vol.40 , pp. 1118-1126
    • Alalwani, S.M.1    Sierigk, J.2    Herr, C.3
  • 52
    • 36148980891 scopus 로고    scopus 로고
    • Cathelicidin LL-37 induces the generation of reactive oxygen species and release of human a-defensins from neutrophils
    • Zheng Y, Niyonsaba F, Ushio H, et al. Cathelicidin LL-37 induces the generation of reactive oxygen species and release of human a-defensins from neutrophils. Br J Dermatol. 2007; 157:1124-1131.
    • (2007) Br J Dermatol , vol.157 , pp. 1124-1131
    • Zheng, Y.1    Niyonsaba, F.2    Ushio, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.