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Volumn 80, Issue 6, 2012, Pages 2076-2088

Toll-like receptor 2 ligand pretreatment attenuates retinal microglial inflammatory response but enhances phagocytic activity toward Staphylococcus aureus

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; TUMOR NECROSIS FACTOR ALPHA; N-PALMITOYL-S-(2,3-BIS(PALMITOYLOXY)PROPYL)CYSTEINYL-SERYL-LYSYL-LYSYL-LYSYL-LYSINE; CD45 ANTIGEN; LIGAND; LIPOPROTEIN; N PALMITOYL S (2,3 BIS(PALMITOYLOXY)PROPYL)CYSTEINYL SERYL LYSYL LYSYL LYSYL LYSINE; PTPRC PROTEIN, MOUSE; TLR2 PROTEIN, MOUSE;

EID: 85047688666     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00149-12     Document Type: Article
Times cited : (76)

References (62)
  • 1
    • 79960973055 scopus 로고    scopus 로고
    • Regulation of innate immune responses in the central nervous system
    • Bajramovic JJ. 2011. Regulation of innate immune responses in the central nervous system. CNS Neurol. Disord. Drug Targets 10:4 -24.
    • (2011) CNS Neurol. Disord. Drug Targets , vol.10 , pp. 4-24
    • Bajramovic, J.J.1
  • 2
    • 0035449358 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity
    • Bal-Price A, Brown GC. 2001. Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. J. Neurosci. 21:6480-6491.
    • (2001) J. Neurosci. , vol.21 , pp. 6480-6491
    • Bal-Price, A.1    Brown, G.C.2
  • 3
    • 33845627116 scopus 로고    scopus 로고
    • Toll-like receptor interactions, tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production
    • Broad A, Kirby JA, Jones DE. 2007. Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production. Immunology 120:103-111.
    • (2007) Immunology , vol.120 , pp. 103-111
    • Broad, A.1    Kirby, J.A.2    Jones, D.E.3
  • 4
    • 69949088960 scopus 로고    scopus 로고
    • NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens
    • Brodsky IE, Monack D. 2009. NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens. Semin. Immunol. 21:199 -207.
    • (2009) Semin. Immunol. , vol.21 , pp. 199-207
    • Brodsky, I.E.1    Monack, D.2
  • 6
    • 33846808899 scopus 로고    scopus 로고
    • Bacterial endophthalmitis Therapeutic challenges and host-pathogen interactions
    • Callegan MC, et al. 2007. Bacterial endophthalmitis: Therapeutic challenges and host-pathogen interactions. Prog. Ret. Eye Res. 26:189 -203.
    • (2007) Prog. Ret. Eye Res. , vol.26 , pp. 189-203
    • Callegan, M.C.1
  • 7
    • 34247235029 scopus 로고    scopus 로고
    • Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
    • Cario E, Gerken G, Podolsky DK. 2007. Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology 132:1359 -1374.
    • (2007) Gastroenterology , vol.132 , pp. 1359-1374
    • Cario, E.1    Gerken, G.2    Podolsky, D.K.3
  • 9
    • 84864605361 scopus 로고    scopus 로고
    • Accumulation of murine subretinal macrophages, effects of age, pigmentation and CX(3)CR1
    • Aging, in press
    • Chinnery HR, et al. Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX(3)CR1. Neurobiol. Aging, in press.
    • Neurobiol
    • Chinnery, H.R.1
  • 10
    • 78651352558 scopus 로고    scopus 로고
    • Endogenous endophthalmitis 10-year experience at a tertiary referral centre
    • Connell PP, et al. 2010. Endogenous endophthalmitis: 10-year experience at a tertiary referral centre. Eye (Lond.) 25:66 -72.
    • (2010) Eye (Lond. ) , vol.25 , pp. 66-72
    • Connell, P.P.1
  • 11
    • 37849046096 scopus 로고    scopus 로고
    • TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours
    • Conroy H, Marshall NA, Mills KH. 2008. TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours. Oncogene 27:168 -180.
    • (2008) Oncogene , vol.27 , pp. 168-180
    • Conroy, H.1    Marshall, N.A.2    Mills, K.H.3
  • 12
    • 79959379095 scopus 로고    scopus 로고
    • Repertoire of microglial and macrophage responses after spinal cord injury
    • David S, Kroner A. 2011. Repertoire of microglial and macrophage responses after spinal cord injury. Nat. Rev. Neurosci. 12:388 -399.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 388-399
    • David, S.1    Kroner, A.2
  • 13
    • 78649971307 scopus 로고    scopus 로고
    • In vitro characterization of the microglial inflammatory response to Streptococcus suis, an important emerging zoonotic agent of meningitis
    • Dominguez-Punaro MDL, et al. 2010. In vitro characterization of the microglial inflammatory response to Streptococcus suis, an important emerging zoonotic agent of meningitis. Infect. Immun. 78:5074 -5085.
    • (2010) Infect. Immun. , vol.78 , pp. 5074-5085
    • Dominguez-Punaro, M.D.L.1
  • 14
    • 0942287664 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus
    • Esen N, Tanga FY, DeLeo JA, Kielian T. 2004. Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus. J. Neurochem 88:746 -758.
    • (2004) J. Neurochem , vol.88 , pp. 746-758
    • Esen, N.1    Tanga, F.Y.2    DeLeo, J.A.3    Kielian, T.4
  • 15
    • 73149095799 scopus 로고    scopus 로고
    • Evaluation of capsular and acapsular strains of S. aureus in an experimental brain abscess model
    • Esen N, Wagoner G, Philips N. 2010. Evaluation of capsular and acapsular strains of S. aureus in an experimental brain abscess model. J. Neuroimmunol. 218:83-93.
    • (2010) J. Neuroimmunol. , vol.218 , pp. 83-93
    • Esen, N.1    Wagoner, G.2    Philips, N.3
  • 16
    • 23844515801 scopus 로고    scopus 로고
    • Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 upregulation
    • Feterowski C, et al. 2005. Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 upregulation. Int. Immunol. 17:1035-1046.
    • (2005) Int. Immunol. , vol.17 , pp. 1035-1046
    • Feterowski, C.1
  • 18
    • 77951950320 scopus 로고    scopus 로고
    • Mechanisms of injury in bacterial meningitis
    • Gerber J, Nau R. 2010. Mechanisms of injury in bacterial meningitis. Curr. Opin. Neurol. 23:312-318.
    • (2010) Curr. Opin. Neurol. , vol.23 , pp. 312-318
    • Gerber, J.1    Nau, R.2
  • 19
    • 0038238035 scopus 로고    scopus 로고
    • Mitigation of neutrophil infiltration in a rat model of early Staphylococcus aureus endophthalmitis
    • Giese MJ, et al. 2003. Mitigation of neutrophil infiltration in a rat model of early Staphylococcus aureus endophthalmitis. Invest. Ophthalmol. Vis. Sci. 44:3077-3082.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 3077-3082
    • Giese, M.J.1
  • 20
    • 33847614263 scopus 로고    scopus 로고
    • Peptidoglycan recognition proteins of the innate immune system
    • Guan R, Mariuzza RA. 2007. Peptidoglycan recognition proteins of the innate immune system. Trends Microbiol. 15:127-134.
    • (2007) Trends Microbiol , vol.15 , pp. 127-134
    • Guan, R.1    Mariuzza, R.A.2
  • 21
    • 35548986304 scopus 로고    scopus 로고
    • Microglia, active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch UK, Kettenmann H. 2007. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat. Neurosci. 10:1387- 1394.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 22
    • 77955421449 scopus 로고    scopus 로고
    • Microglia in the healthy and degenerating retina, insights from novel mouse models
    • Karlstetter M, Ebert S, Langmann T. 2010. Microglia in the healthy and degenerating retina: insights from novel mouse models. Immunobiology 215:685- 691.
    • (2010) Immunobiology , vol.215 , pp. 685-691
    • Karlstetter, M.1    Ebert, S.2    Langmann, T.3
  • 23
    • 36049033394 scopus 로고    scopus 로고
    • Signaling to NF-κB by Toll-like receptors
    • Kawai T, Akira S. 2007. Signaling to NF-κB by Toll-like receptors. Trends Mol. Med. 13:460-469.
    • (2007) Trends Mol. Med. , vol.13 , pp. 460-469
    • Kawai, T.1    Akira, S.2
  • 24
    • 14844348476 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia
    • Kielian T, Esen N, Bearden ED. 2005. Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia. Glia 49:567-576.
    • (2005) Glia , vol.49 , pp. 567-576
    • Kielian, T.1    Esen, N.2    Bearden, E.D.3
  • 25
    • 33748696772 scopus 로고    scopus 로고
    • The role of Toll-like receptors in CNS response to microbial challenge
    • Konat GW, Kielian T, Marriott I. 2006. The role of Toll-like receptors in CNS response to microbial challenge. J. Neurochem. 99:1-12.
    • (2006) J. Neurochem. , vol.99 , pp. 1-12
    • Konat, G.W.1    Kielian, T.2    Marriott, I.3
  • 26
    • 0030222037 scopus 로고    scopus 로고
    • Microglia, a sensor for pathological events in the CNS
    • Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 27
    • 77958105033 scopus 로고    scopus 로고
    • Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection
    • Kumar A, Gao N, Standiford TJ, Gallo RL, Yu FS. 2010. Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection. Microbes Infect. 12:978 -989.
    • (2010) Microbes Infect , vol.12 , pp. 978-989
    • Kumar, A.1    Gao, N.2    Standiford, T.J.3    Gallo, R.L.4    Yu, F.S.5
  • 28
    • 37749037714 scopus 로고    scopus 로고
    • Flagellin suppresses the inflammatory response and enhances bacterial clearance in a murine model of Pseudomonas aeruginosa keratitis
    • Kumar A, Hazlett LD, Yu FS. 2008. Flagellin suppresses the inflammatory response and enhances bacterial clearance in a murine model of Pseudomonas aeruginosa keratitis. Infect. Immun. 76:89 -96.
    • (2008) Infect. Immun. , vol.76 , pp. 89-96
    • Kumar, A.1    Hazlett, L.D.2    Yu, F.S.3
  • 29
    • 75649084602 scopus 로고    scopus 로고
    • Toll-like receptor 2 ligand-induced protection against bacterial endophthalmitis
    • Kumar A, Singh CN, Glybina IV, Mahmoud TH, Yu FS. 2010. Toll-like receptor 2 ligand-induced protection against bacterial endophthalmitis. J. Infect. Dis. 201:255-263.
    • (2010) J. Infect. Dis. , vol.201 , pp. 255-263
    • Kumar, A.1    Singh, C.N.2    Glybina, I.V.3    Mahmoud, T.H.4    Yu, F.S.5
  • 30
    • 35748965018 scopus 로고    scopus 로고
    • Modulation of corneal epithelial innate immune response to pseudomonas infection by flagellin pretreatment
    • Kumar A, Yin J, Zhang J, Yu FS. 2007. Modulation of corneal epithelial innate immune response to pseudomonas infection by flagellin pretreatment. Invest. Ophthalmol. Vis. Sci. 48:4664-4670.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 4664-4670
    • Kumar, A.1    Yin, J.2    Zhang, J.3    Yu, F.S.4
  • 31
    • 4644310244 scopus 로고    scopus 로고
    • Innate immune response of corneal epithelial cells to Staphylococcus aureus infection role of peptidoglycan in stimulating proinflammatory cytokine secretion
    • Kumar A, Zhang J, Yu FS. 2004. Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: role of peptidoglycan in stimulating proinflammatory cytokine secretion. Invest. Ophthalmol. Vis. Sci. 45:3513-3522.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 3513-3522
    • Kumar, A.1    Zhang, J.2    Yu, F.S.3
  • 32
    • 0035158914 scopus 로고    scopus 로고
    • Improved innate immunity of endotoxintolerant mice increases resistance to Salmonella enterica serovar Typhimurium infection despite attenuated cytokine response
    • Lehner MD, et al. 2001. Improved innate immunity of endotoxintolerant mice increases resistance to Salmonella enterica serovar Typhimurium infection despite attenuated cytokine response. Infect. Immun. 69:463- 471.
    • (2001) Infect. Immun. , vol.69 , pp. 463-471
    • Lehner, M.D.1
  • 33
    • 0036377910 scopus 로고    scopus 로고
    • Immunology of Staphylococcal biofilm infections in the eye new tools to study biofilm endophthalmitis
    • Leid JG, Costerton JW, Shirtliff ME, Gilmore MS, Engelbert M. 2002. Immunology of Staphylococcal biofilm infections in the eye: new tools to study biofilm endophthalmitis. DNA Cell Biol. 21:405- 413.
    • (2002) DNA Cell Biol , vol.21 , pp. 405-413
    • Leid, J.G.1    Costerton, J.W.2    Shirtliff, M.E.3    Gilmore, M.S.4    Engelbert, M.5
  • 34
    • 33746431489 scopus 로고    scopus 로고
    • Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation
    • Li CH, Wang JH, Redmond HP. 2006. Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation. J. Leukoc. Biol. 79:867- 875.
    • (2006) J. Leukoc. Biol. , vol.79 , pp. 867-875
    • Li, C.H.1    Wang, J.H.2    Redmond, H.P.3
  • 35
    • 79952434212 scopus 로고    scopus 로고
    • Peptidoglycan induces interleukin-6 expression through the TLR2 receptor, JNK, c-Jun, and AP-1 pathways in microglia
    • Lin HY, et al. 2011. Peptidoglycan induces interleukin-6 expression through the TLR2 receptor, JNK, c-Jun, and AP-1 pathways in microglia. J. Cell. Physiol. 226:1573-1582.
    • (2011) J. Cell. Physiol. , vol.226 , pp. 1573-1582
    • Lin, H.Y.1
  • 36
    • 77954167202 scopus 로고    scopus 로고
    • Microglial activation by Citrobacter koseri is mediated by TLR4-and MyD88-dependent pathways
    • Liu S, Kielian T. 2009. Microglial activation by Citrobacter koseri is mediated by TLR4- and MyD88-dependent pathways. J. Immunol. 183: 5537-5547.
    • (2009) J. Immunol. , vol.183 , pp. 5537-5547
    • Liu, S.1    Kielian, T.2
  • 37
    • 77952574671 scopus 로고    scopus 로고
    • NOD2 mediates inflammatory responses of primary murine glia to Streptococcus pneumoniae
    • Liu X, Chauhan VS, Young AB, Marriott I. 2010. NOD2 mediates inflammatory responses of primary murine glia to Streptococcus pneumoniae. Glia 58:839-847.
    • (2010) Glia , vol.58 , pp. 839-847
    • Liu, X.1    Chauhan, V.S.2    Young, A.B.3    Marriott, I.4
  • 38
    • 70449532049 scopus 로고    scopus 로고
    • Microglia in infectious diseases of the central nervous system
    • Mariani MM, Kielian T. 2009. Microglia in infectious diseases of the central nervous system. J. Neuroimmune Pharmacol. 4:448-461.
    • (2009) J. Neuroimmune Pharmacol. , vol.4 , pp. 448-461
    • Mariani, M.M.1    Kielian, T.2
  • 39
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mousemacrophages dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression
    • Medvedev AE, Kopydlowski KM, Vogel SN. 2000. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mousemacrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression. J. Immunol. 164:5564 -5574.
    • (2000) J. Immunol. , vol.164 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 40
    • 33745945755 scopus 로고    scopus 로고
    • Tolerance to microbial TLR ligands, molecular mechanisms and relevance to disease
    • Medvedev AE, Sabroe I, Hasday JD, Vogel SN. 2006. Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease. J. Endotoxin Res. 12:133-150.
    • (2006) J. Endotoxin Res. , vol.12 , pp. 133-150
    • Medvedev, A.E.1    Sabroe, I.2    Hasday, J.D.3    Vogel, S.N.4
  • 41
    • 33947629255 scopus 로고    scopus 로고
    • Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
    • Miyake K. 2007. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin. Immunol. 19:3-10.
    • (2007) Semin. Immunol. , vol.19 , pp. 3-10
    • Miyake, K.1
  • 42
  • 43
    • 33751555738 scopus 로고    scopus 로고
    • The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands
    • Mullaly SC, Kubes P. 2006. The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands. J. Immunol. 177: 8154-8163.
    • (2006) J. Immunol. , vol.177 , pp. 8154-8163
    • Mullaly, S.C.1    Kubes, P.2
  • 44
    • 67749144000 scopus 로고    scopus 로고
    • Endogenous endophthalmitis caused by methicillin-resistant Staphylococcus aureus (MRSA)
    • Ness T, Schneider C. 2009. Endogenous endophthalmitis caused by methicillin-resistant Staphylococcus aureus (MRSA). Retina 29:831- 834.
    • (2009) Retina , vol.29 , pp. 831-834
    • Ness, T.1    Schneider, C.2
  • 45
    • 58449119213 scopus 로고    scopus 로고
    • Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5α and Escherichia coli K1 strains by murine microglial cells
    • Ribes S, et al. 2009. Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5α and Escherichia coli K1 strains by murine microglial cells. Infect. Immun. 77:557-564.
    • (2009) Infect. Immun. , vol.77 , pp. 557-564
    • Ribes, S.1
  • 46
    • 76749104336 scopus 로고    scopus 로고
    • Toll-like receptor stimulation enhances phagocytosis and intracellular killing of nonencapsulated and encapsulated Streptococcus pneumoniae by murine microglia
    • Ribes S, et al. 2010. Toll-like receptor stimulation enhances phagocytosis and intracellular killing of nonencapsulated and encapsulated Streptococcus pneumoniae by murine microglia. Infect. Immun. 78:865- 871.
    • (2010) Infect. Immun. , vol.78 , pp. 865-871
    • Ribes, S.1
  • 48
    • 64049102506 scopus 로고    scopus 로고
    • Nucleotide oligomerization domain-2 (NOD2)-induced uveitis, dependence on IFN-gamma
    • Rosenzweig HL, et al. 2009. Nucleotide oligomerization domain-2 (NOD2)-induced uveitis: dependence on IFN-gamma. Invest. Ophthalmol. Vis. Sci. 50:1739 -1745.
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 1739-1745
    • Rosenzweig, H.L.1
  • 49
    • 45549085856 scopus 로고    scopus 로고
    • NOD2, the gene responsible for familial granulomatous uveitis, in a mouse model of uveitis
    • Rosenzweig HL, et al. 2008. NOD2, the gene responsible for familial granulomatous uveitis, in a mouse model of uveitis. Invest. Ophthalmol. Vis. Sci. 49:1518 -1524.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 1518-1524
    • Rosenzweig, H.L.1
  • 50
    • 0018905247 scopus 로고
    • Enhanced phagocytosis and bactericidal activity of hepatic reticuloendothelial system during endotoxin tolerance
    • Ruggiero G, Andreana A, Utili R, Galante D. 1980. Enhanced phagocytosis and bactericidal activity of hepatic reticuloendothelial system during endotoxin tolerance. Infect. Immun. 27:798-803.
    • (1980) Infect. Immun. , vol.27 , pp. 798-803
    • Ruggiero, G.1    Andreana, A.2    Utili, R.3    Galante, D.4
  • 51
    • 78650240246 scopus 로고    scopus 로고
    • The role of TLR2 in nerve injuryinduced neuropathic pain is essentially mediated through macrophages in peripheral inflammatory response
    • Shi XQ, Zekki H, Zhang J. 2011. The role of TLR2 in nerve injuryinduced neuropathic pain is essentially mediated through macrophages in peripheral inflammatory response. Glia 59:231-241.
    • (2011) Glia , vol.59 , pp. 231-241
    • Shi, X.Q.1    Zekki, H.2    Zhang, J.3
  • 52
    • 80355130080 scopus 로고    scopus 로고
    • Evisceration of mouse vitreous and retina for proteomic analyses
    • 2011
    • Skeie JM, Tsang SH, Mahajan VB. 2011. Evisceration of mouse vitreous and retina for proteomic analyses. J. Vis. Exp. 2011:2795.
    • (2011) J. Vis. Exp. , pp. 2795
    • Skeie, J.M.1    Tsang, S.H.2    Mahajan, V.B.3
  • 53
    • 75649087741 scopus 로고    scopus 로고
    • CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
    • Stewart CR, et al. 2010. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat. Immunol. 11:155-161.
    • (2010) Nat. Immunol. , vol.11 , pp. 155-161
    • Stewart, C.R.1
  • 54
    • 0034669910 scopus 로고    scopus 로고
    • Cutting edge TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection
    • Takeuchi O, Hoshino K, Akira S. 2000. Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection. J. Immunol. 165:5392-5396.
    • (2000) J. Immunol. , vol.165 , pp. 5392-5396
    • Takeuchi, O.1    Hoshino, K.2    Akira, S.3
  • 55
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • Takeuchi O, et al. 1999. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11:443- 451.
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1
  • 56
    • 27744598776 scopus 로고    scopus 로고
    • Endotoxin priming improves clearance of Pseudomonas aeruginosa in wild-type and interleukin-10 knockout mice
    • Varma TK, et al. 2005. Endotoxin priming improves clearance of Pseudomonas aeruginosa in wild-type and interleukin-10 knockout mice. Infect. Immun. 73:7340 -7347.
    • (2005) Infect. Immun. , vol.73 , pp. 7340-7347
    • Varma, T.K.1
  • 57
    • 79957925285 scopus 로고    scopus 로고
    • Roles of Toll-like receptor 2 (TLR2) and superantigens on adaptive immune responses during CNS staphylococcal infection
    • Vidlak D, Mariani MM, Aldrich A, Liu S, Kielian T. 2011. Roles of Toll-like receptor 2 (TLR2) and superantigens on adaptive immune responses during CNS staphylococcal infection. Brain Behav. Immun. 25: 905-914.
    • (2011) Brain Behav. Immun. , vol.25 , pp. 905-914
    • Vidlak, D.1    Mariani, M.M.2    Aldrich, A.3    Liu, S.4    Kielian, T.5
  • 58
    • 34248385381 scopus 로고    scopus 로고
    • Flagellin suppresses epithelial apoptosis and limits disease during enteric infection
    • Vijay-Kumar M, et al. 2006. Flagellin suppresses epithelial apoptosis and limits disease during enteric infection. Am. J. Pathol. 169:1686 -1700.
    • (2006) Am. J. Pathol. , vol.169 , pp. 1686-1700
    • Vijay-Kumar, M.1
  • 59
    • 77956056395 scopus 로고    scopus 로고
    • Walnut extract inhibits LPS-induced activation of BV-2 microglia via internalization of TLR4 possible involvement of phospholipase D2
    • Willis LM, Bielinski DF, Fisher DR, Matthan NR, Joseph JA. 2010. Walnut extract inhibits LPS-induced activation of BV-2 microglia via internalization of TLR4: possible involvement of phospholipase D2. Inflammation 33:325-333.
    • (2010) Inflammation , vol.33 , pp. 325-333
    • Willis, L.M.1    Bielinski, D.F.2    Fisher, D.R.3    Matthan, N.R.4    Joseph, J.A.5
  • 61
    • 41649115159 scopus 로고    scopus 로고
    • TLR2 -promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity
    • Zahringer U, Lindner B, Inamura S, Heine H, Alexander C. 2008. TLR2 - promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity. Immunobiology 213:205-224.
    • (2008) Immunobiology , vol.213 , pp. 205-224
    • Zahringer, U.1    Lindner, B.2    Inamura, S.3    Heine, H.4    Alexander, C.5
  • 62
    • 78650834047 scopus 로고    scopus 로고
    • Essential role of Toll-like receptor 2 in morphineinduced microglia activation in mice
    • Zhang Y, et al. 2011. Essential role of Toll-like receptor 2 in morphineinduced microglia activation in mice. Neurosci. Lett. 489:43- 47.
    • (2011) Neurosci. Lett. , vol.489 , pp. 43-47
    • Zhang, Y.1


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