-
1
-
-
68149124572
-
Quantitative signal detection using spontaneous ADR reporting
-
Bate A., Evans S.J.W. Quantitative signal detection using spontaneous ADR reporting. Pharmacoepidem Drug Safety 2009, 18(6):427-436.
-
(2009)
Pharmacoepidem Drug Safety
, vol.18
, Issue.6
, pp. 427-436
-
-
Bate, A.1
Evans, S.J.W.2
-
2
-
-
84870987376
-
Automated design of ligands to polypharmacological profiles
-
Besnard J., Ruda G.F., Setola V., Abecassis K., Rodriguiz R.M., Huang X.P., et al. Automated design of ligands to polypharmacological profiles. Nature 2012, 492(7428):215-220.
-
(2012)
Nature
, vol.492
, Issue.7428
, pp. 215-220
-
-
Besnard, J.1
Ruda, G.F.2
Setola, V.3
Abecassis, K.4
Rodriguiz, R.M.5
Huang, X.P.6
-
3
-
-
84255172340
-
Predicting adverse drug events using pharmacological network models
-
114ra27
-
Cami A., Arnold A., Manzi S., Reis B. Predicting adverse drug events using pharmacological network models. Sci Transl Med 2011, 3(114):114ra27.
-
(2011)
Sci Transl Med
, vol.3
, Issue.114
-
-
Cami, A.1
Arnold, A.2
Manzi, S.3
Reis, B.4
-
4
-
-
0345863927
-
The unified medical language system (UMLS): integrating biomedical terminology
-
Bodenreider O. The unified medical language system (UMLS): integrating biomedical terminology. Nucl Acid Res 2004, 32(suppl 1):D267-D270.
-
(2004)
Nucl Acid Res
, vol.32
, pp. D267-D270
-
-
Bodenreider, O.1
-
5
-
-
47249146126
-
Drug target identification using side-effect similarity
-
Campillos M., Kuhn M., Gavin A.C., Jensen L.J., Bork P. Drug target identification using side-effect similarity. Science 2008, 321(5886):263-266.
-
(2008)
Science
, vol.321
, Issue.5886
, pp. 263-266
-
-
Campillos, M.1
Kuhn, M.2
Gavin, A.C.3
Jensen, L.J.4
Bork, P.5
-
6
-
-
84856055845
-
Recycling side-effects into clinical markers for drug repositioning
-
Duran-Frigola M., Aloy P. Recycling side-effects into clinical markers for drug repositioning. Genome Med 2012, 4(3).
-
(2012)
Genome Med
, vol.4
, Issue.3
-
-
Duran-Frigola, M.1
Aloy, P.2
-
7
-
-
32344440237
-
Analysis of drug-induced effect patterns to link structure and side effects of medicines
-
Fliri A.F., Loging W.T., Thadeio P.F., Volkmann R.A. Analysis of drug-induced effect patterns to link structure and side effects of medicines. Nature Chem Biol 2005, 1(7):389-397.
-
(2005)
Nature Chem Biol
, vol.1
, Issue.7
, pp. 389-397
-
-
Fliri, A.F.1
Loging, W.T.2
Thadeio, P.F.3
Volkmann, R.A.4
-
8
-
-
70350236893
-
Discovering novel adverse drug events using natural language processing and mining of the electronic health record
-
Springer, Berlin Heidelberg
-
Friedman C. Discovering novel adverse drug events using natural language processing and mining of the electronic health record. Artificial intelligence in medicine 2009, 1-5. Springer, Berlin Heidelberg.
-
(2009)
Artificial intelligence in medicine
, pp. 1-5
-
-
Friedman, C.1
-
9
-
-
84942412129
-
Extraction of potential adverse drug events from medical case reports
-
Gurulingappa H., MateenRajput A., Toldo L. Extraction of potential adverse drug events from medical case reports. J Biomed Semantics 2012, 3(1):15.
-
(2012)
J Biomed Semantics
, vol.3
, Issue.1
, pp. 15
-
-
Gurulingappa, H.1
MateenRajput, A.2
Toldo, L.3
-
10
-
-
76749092270
-
The WEKA data mining software: an update
-
Hall M., Frank E., Holmes G., Pfahringer B., Reutemann P., Witten I.H. The WEKA data mining software: an update. ACM SIGKDD Explor Newslett 2009, 11(1):10-18.
-
(2009)
ACM SIGKDD Explor Newslett
, vol.11
, Issue.1
, pp. 10-18
-
-
Hall, M.1
Frank, E.2
Holmes, G.3
Pfahringer, B.4
Reutemann, P.5
Witten, I.H.6
-
11
-
-
77953811317
-
Prediction of adverse drug reactions using decision tree modeling
-
Hammann F., Gutmann H., Vogt N., Helma C., Drewe J. Prediction of adverse drug reactions using decision tree modeling. Clin Pharmacol Therapeut 2010, 88(1):52-59.
-
(2010)
Clin Pharmacol Therapeut
, vol.88
, Issue.1
, pp. 52-59
-
-
Hammann, F.1
Gutmann, H.2
Vogt, N.3
Helma, C.4
Drewe, J.5
-
12
-
-
84861346585
-
Novel data-mining methodologies for adverse drug event discovery and analysis
-
Harpaz R., DuMouchel W., Shah N.H., Madigan D., Ryan P., Friedman C. Novel data-mining methodologies for adverse drug event discovery and analysis. Clin Pharmacol Therapeut 2012, 91(6):1010-1021.
-
(2012)
Clin Pharmacol Therapeut
, vol.91
, Issue.6
, pp. 1010-1021
-
-
Harpaz, R.1
DuMouchel, W.2
Shah, N.H.3
Madigan, D.4
Ryan, P.5
Friedman, C.6
-
13
-
-
84875459651
-
Computational drug repositioning: from data to therapeutics
-
Hurle M.R., Yang L., Xie Q., Rajpal D.K., Sanseau P., Agarwal P. Computational drug repositioning: from data to therapeutics. Clinical Pharmacology & Therapeutics 2013, 93(4):335-341. 10.1038/clpt.2013.1.
-
(2013)
Clinical Pharmacology & Therapeutics
, vol.93
, Issue.4
, pp. 335-341
-
-
Hurle, M.R.1
Yang, L.2
Xie, Q.3
Rajpal, D.K.4
Sanseau, P.5
Agarwal, P.6
-
14
-
-
70449634957
-
Predicting new molecular targets for known drugs
-
Keiser M.J., Setola V., Irwin J.J., Laggner C., Abbas A.I., Hufeisen S.J., et al. Predicting new molecular targets for known drugs. Nature 2009, 462(7270):175-181.
-
(2009)
Nature
, vol.462
, Issue.7270
, pp. 175-181
-
-
Keiser, M.J.1
Setola, V.2
Irwin, J.J.3
Laggner, C.4
Abbas, A.I.5
Hufeisen, S.J.6
-
15
-
-
76149120425
-
A side effect resource to capture phenotypic effects of drugs
-
Kuhn M., Campillos M., Letunic I., Jensen L.J., Bork P. A side effect resource to capture phenotypic effects of drugs. Mol Syst Biol 2010, 6(1).
-
(2010)
Mol Syst Biol
, vol.6
, Issue.1
-
-
Kuhn, M.1
Campillos, M.2
Letunic, I.3
Jensen, L.J.4
Bork, P.5
-
16
-
-
84902548120
-
Towards internet-age pharmacovigilance: extracting adverse drug reactions from user posts to health-related social networks
-
Association for Computational Linguistics
-
Leaman R., Wojtulewicz L., Sullivan R., Skariah A., Yang J., Gonzalez G. Towards internet-age pharmacovigilance: extracting adverse drug reactions from user posts to health-related social networks. Proceedings of the 2010 workshop on biomedical natural language processing 2010, 117-125. Association for Computational Linguistics.
-
(2010)
Proceedings of the 2010 workshop on biomedical natural language processing
, pp. 117-125
-
-
Leaman, R.1
Wojtulewicz, L.2
Sullivan, R.3
Skariah, A.4
Yang, J.5
Gonzalez, G.6
-
17
-
-
84862510972
-
Large-scale prediction and testing of drug activity on side-effect targets
-
Lounkine E., Keiser M.J., Whitebread S., Mikhailov D., Hamon J., Jenkins J.L., et al. Large-scale prediction and testing of drug activity on side-effect targets. Nature 2012, 486(7403):361-367.
-
(2012)
Nature
, vol.486
, Issue.7403
, pp. 361-367
-
-
Lounkine, E.1
Keiser, M.J.2
Whitebread, S.3
Mikhailov, D.4
Hamon, J.5
Jenkins, J.L.6
-
18
-
-
79955969387
-
Predicting drug side-effect profiles: a chemical fragment-based approach
-
Pauwels E., Stoven V., Yamanishi Y. Predicting drug side-effect profiles: a chemical fragment-based approach. BMC Bioinform 2011, 12(1):169.
-
(2011)
BMC Bioinform
, vol.12
, Issue.1
, pp. 169
-
-
Pauwels, E.1
Stoven, V.2
Yamanishi, Y.3
-
19
-
-
68849085448
-
The new sentinel network improving the evidence of medical-product safety
-
Platt R., Wilson M., Chan K.A., Benner J.S., Marchibroda J., McClellan M. The new sentinel network improving the evidence of medical-product safety. New Engl J Med 2009, 361(7):645-647.
-
(2009)
New Engl J Med
, vol.361
, Issue.7
, pp. 645-647
-
-
Platt, R.1
Wilson, M.2
Chan, K.A.3
Benner, J.S.4
Marchibroda, J.5
McClellan, M.6
-
20
-
-
79959380528
-
Predicting adverse drug reactions using publicly available PubChem BioAssay data
-
Pouliot Y., Chiang A.P., Butte A.J. Predicting adverse drug reactions using publicly available PubChem BioAssay data. Clin Pharmacol Therapeut 2011, 90(1):90-99.
-
(2011)
Clin Pharmacol Therapeut
, vol.90
, Issue.1
, pp. 90-99
-
-
Pouliot, Y.1
Chiang, A.P.2
Butte, A.J.3
-
21
-
-
79951981575
-
Reporting of serious adverse drug reactions of targeted anticancer agents in pivotal phase III clinical trials
-
Seruga B., et al. Reporting of serious adverse drug reactions of targeted anticancer agents in pivotal phase III clinical trials. J Clin Oncol 2011, 29:174-185.
-
(2011)
J Clin Oncol
, vol.29
, pp. 174-185
-
-
Seruga, B.1
-
22
-
-
80053254385
-
Using information mining of the medical literature to improve drug safety
-
Shetty K.D., Dalal S.R. Using information mining of the medical literature to improve drug safety. J Am Med Inform Assoc 2011, 18(5):668-674.
-
(2011)
J Am Med Inform Assoc
, vol.18
, Issue.5
, pp. 668-674
-
-
Shetty, K.D.1
Dalal, S.R.2
-
23
-
-
84858329412
-
Data-driven prediction of drug effects and interactions
-
125ra31
-
Tatonetti N.P., Patrick P.Y., Daneshjou R., Altman R.B. Data-driven prediction of drug effects and interactions. Sci Transl Med 2012, 4(125):125ra31.
-
(2012)
Sci Transl Med
, vol.4
, Issue.125
-
-
Tatonetti, N.P.1
Patrick, P.Y.2
Daneshjou, R.3
Altman, R.B.4
-
24
-
-
84866611528
-
Pharmacogenomics knowledge for personalized medicine
-
Whirl-Carrillo M., McDonagh E.M., Hebert J.M., Gong Li., Sangkuhl K., Thorn C.F., et al. Pharmacogenomics knowledge for personalized medicine. Clin Pharmacol Therapeut 2012, 92(4):414-417.
-
(2012)
Clin Pharmacol Therapeut
, vol.92
, Issue.4
, pp. 414-417
-
-
Whirl-Carrillo, M.1
McDonagh, E.M.2
Hebert, J.M.3
Gong, L.4
Sangkuhl, K.5
Thorn, C.F.6
-
25
-
-
33644876210
-
DrugBank: a comprehensive resource for in silico drug discovery and exploration
-
Wishart D.S., Knox C., Guo A.C., Shrivastava S., Hassanali M., Stothard P., et al. DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucl Acids Res 2006, 34(suppl 1):D668-D672.
-
(2006)
Nucl Acids Res
, vol.34
, pp. D668-D672
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
Shrivastava, S.4
Hassanali, M.5
Stothard, P.6
-
26
-
-
79955562721
-
Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavir
-
Xie L., Evangelidis T., Xie L., Bourne P.E. Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavir. PLoS Comput Biol 2011, 7(4):e1002037.
-
(2011)
PLoS Comput Biol
, vol.7
, Issue.4
, pp. e1002037
-
-
Xie, L.1
Evangelidis, T.2
Xie, L.3
Bourne, P.E.4
-
27
-
-
84908035482
-
Automatic construction and integrated analysis of a cancer drug side effect knowledge base
-
Xu R., Wang Q. Automatic construction and integrated analysis of a cancer drug side effect knowledge base. J Am Med Inform Assoc 2013, 10.1136/amiajnl-2012-001584.
-
(2013)
J Am Med Inform Assoc
-
-
Xu, R.1
Wang, Q.2
-
28
-
-
84895421624
-
Automatic signal prioritizing and filtering approaches in detecting post-marketing cardiovascular events associated with targeted cancer drugs from the FDA Adverse Event Reporting System (FAERS)
-
Xu R., Wang Q. Automatic signal prioritizing and filtering approaches in detecting post-marketing cardiovascular events associated with targeted cancer drugs from the FDA Adverse Event Reporting System (FAERS). J Biomed Informs 2014, 171-177.
-
(2014)
J Biomed Informs
, pp. 171-177
-
-
Xu, R.1
Wang, Q.2
-
29
-
-
84893172915
-
Large-scale combining signals from both biomedical literature and the FDA adverse event reporting system (FAERS) to improve post-marketing drug safety signal detection
-
Xu R., Wang Q. Large-scale combining signals from both biomedical literature and the FDA adverse event reporting system (FAERS) to improve post-marketing drug safety signal detection. BMC Bioinform 2014, 15:17. 10.1186/10.1186/1471-2105-15-17.
-
(2014)
BMC Bioinform
, vol.15
, pp. 17
-
-
Xu, R.1
Wang, Q.2
-
30
-
-
84908037538
-
Automatic construction of a large-scale and accurate drug-side-effect association knowledge base from biomedical literature
-
pii: S1532-0464(14)00138-5
-
Xu R., Wang Q. Automatic construction of a large-scale and accurate drug-side-effect association knowledge base from biomedical literature. J Biomed Inform 2014, 51:191-199. pii: S1532-0464(14)00138-5. 10.1016/j.jbi.2014.05.013.
-
(2014)
J Biomed Inform
, vol.51
, pp. 191-199
-
-
Xu, R.1
Wang, Q.2
-
31
-
-
84924499250
-
Comparing a knowledge-driven approach to a supervised machine learning approach in constructing a large-scale drug-side effect relationship knowledge base for computational drug discovery
-
Xu R, Wang Q. Comparing a knowledge-driven approach to a supervised machine learning approach in constructing a large-scale drug-side effect relationship knowledge base for computational drug discovery. In: International symposium on bioinformatics research and applications (ISBRA) 2014 conference; 2014.
-
(2014)
International symposium on bioinformatics research and applications (ISBRA) 2014 conference
-
-
Xu, R.1
Wang, Q.2
-
32
-
-
65349157361
-
Active computerized pharmacovigilance using natural language processing, statistics, and electronic health records: a feasibility study
-
Wang X., Hripcsak G., Markatou M., Friedman C. Active computerized pharmacovigilance using natural language processing, statistics, and electronic health records: a feasibility study. J Am Med Inform Assoc 2009, 16(3):328-337.
-
(2009)
J Am Med Inform Assoc
, vol.16
, Issue.3
, pp. 328-337
-
-
Wang, X.1
Hripcsak, G.2
Markatou, M.3
Friedman, C.4
-
33
-
-
84879892778
-
Web-scale pharmacovigilance: listening to signals from the crowd
-
White R.W., Tatonetti N.P., Shah N.H., Altman R.B., Horvitz E. Web-scale pharmacovigilance: listening to signals from the crowd. J Am Med Inform Assoc 2013, 20(3):404-408.
-
(2013)
J Am Med Inform Assoc
, vol.20
, Issue.3
, pp. 404-408
-
-
White, R.W.1
Tatonetti, N.P.2
Shah, N.H.3
Altman, R.B.4
Horvitz, E.5
-
34
-
-
79953669856
-
Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactomeclozapine-induced agranulocytosis as a case study
-
Yang L., Wang K., Chen J., Jegga A.G., Luo H., Shi L., et al. Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactomeclozapine-induced agranulocytosis as a case study. PLoS Comput Biol 2011, 7(3):e1002016.
-
(2011)
PLoS Comput Biol
, vol.7
, Issue.3
, pp. e1002016
-
-
Yang, L.1
Wang, K.2
Chen, J.3
Jegga, A.G.4
Luo, H.5
Shi, L.6
-
35
-
-
35148838537
-
Drugtarget network
-
Yildirim M.A., Goh K.I., Cusick M.E., Barabsi A.L., Vidal M. Drugtarget network. Nature Biotechnol 2007, 25(10):1119.
-
(2007)
Nature Biotechnol
, vol.25
, Issue.10
, pp. 1119
-
-
Yildirim, M.A.1
Goh, K.I.2
Cusick, M.E.3
Barabsi, A.L.4
Vidal, M.5
|