Matrix stiffness determines the fate of nucleus pulposus-derived stem cells

Biomaterials

Volumn 49, Issue , 2015, Pages 68-76

  Navaro, Yosi ^a   Bleich Kimelman, Nadav ^a   Hazanov, Lena ^b   Mironi Harpaz, Iris ^b   Shachaf, Yonatan ^b   Garty, Shai ^c,f   Smith, Yoav ^d   Pelled, Gadi ^a,e   Gazit, Dan ^a,e   Seliktar, Dror ^b   Gazit, Zulma ^a,e  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d HEBREW UNIVERSITY   (Israel)

^e CEDARS SINAI MEDICAL CENTER   (United States)

^f MAX PLANCK INSTITUTE FOR INTELLIGENT SYSTEMS   (Germany)

Author keywords

Elasticity; Fibrinogen; Hydrogel; Intervertebral disc; Matrix stiffness; Stem cells

Indexed keywords

CYTOLOGY; DISEASE CONTROL; ELASTIC MODULI; ELASTICITY; HYDROGELS; SCANNING ELECTRON MICROSCOPY; STEM CELLS; STIFFNESS;

CELL MATRIX INTERACTIONS; CHONDROGENIC DIFFERENTIATION; FIBRINOGEN; INTERVERTEBRAL DISCS; OSTEOGENIC DIFFERENTIATION; PATHOLOGICAL CONDITIONS; SHEAR STORAGE MODULUS; THREE DIMENSIONAL MATRICES;

STIFFNESS MATRIX;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL INTERACTION; CELL PROLIFERATION; CELL SURVIVAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; RIGIDITY; SCANNING ELECTRON MICROSCOPY; SHEAR STRESS; STEM CELL; ANIMAL; BIOMECHANICS; CELL LINEAGE; CELL MEMBRANE; CELL SHAPE; CHONDROGENESIS; CYTOLOGY; DRUG EFFECTS; FLOW KINETICS; HYDROGEL; INTERVERTEBRAL DISK; METABOLISM; PHARMACOLOGY; PHYSIOLOGY; PIG; YOUNG MODULUS;

ETHYLENEDIAMINE DERIVATIVE; HYDROGEL;

ANIMALS; BIOMECHANICAL PHENOMENA; CELL DIFFERENTIATION; CELL LINEAGE; CELL SHAPE; CELL SURVIVAL; CELL-MATRIX JUNCTIONS; CELLS, CULTURED; CHONDROGENESIS; ELASTIC MODULUS; ETHYLENEDIAMINES; EXTRACELLULAR MATRIX; HYDROGELS; INTERVERTEBRAL DISC; RHEOLOGY; STEM CELLS; SUS SCROFA;

EID: 84924455748     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.01.021     Document Type: Article

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