Prion Infections and Anti-PrP Antibodies Trigger Converging Neurotoxic Pathways

PLoS Pathogens

Volumn 11, Issue 2, 2015, Pages

  Herrmann, Uli S ^a   Sonati, Tiziana ^a   Falsig, Jeppe ^a   Reimann, Regina R ^a   Dametto, Paolo ^a   O’Connor, Tracy ^a   Li, Bei ^a   Lau, Agnes ^a   Hornemann, Simone ^a   Sorce, Silvia ^a   Wagner, Uli ^b   Sanoudou, Despina ^c   Aguzzi, Adriano ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; PRION PROTEIN ANTIBODY; PROTEIN ELF2; PROTEIN PERK; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ANTIBODY; PERK KINASE; PRION PROTEIN; PROTEIN KINASE R;

ANIMAL TISSUE; ARTICLE; CELL ASSAY; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; EXCITOTOXICITY; GENE EXPRESSION; GENE REGULATORY NETWORK; IMMUNOFLUORESCENCE; MICROARRAY ANALYSIS; MOUSE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRION DISEASE; PROTEIN ANALYSIS; PROTEIN INTERACTION; SCRAPIE CELL ASSAY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UNFOLDED PROTEIN RESPONSE; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; GENETICS; IMMUNOLOGY; PATHOLOGY; TRANSGENIC MOUSE;

MUS;

ANIMALS; ANTIBODIES; EIF-2 KINASE; MICE; MICE, TRANSGENIC; PRION DISEASES; PRPSC PROTEINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84924390410     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004662     Document Type: Article

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