VEGF promotes osteogenic differentiation of ASCs on ordered fluorapatite surfaces

Journal of Biomedical Materials Research - Part A

Volumn 103, Issue 2, 2015, Pages 639-645

  Clark, D ^a   Wang, X ^a,b   Chang, S ^a   Czajka Jakubowska, A ^c   Clarkson, B H ^a   Liu, J ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

differentiation; fluorapatite; mineralization; signaling pathway; vascular endothelial growth factor

Indexed keywords

ALIZARIN; BONE; CELL ENGINEERING; CELL SIGNALING; DIFFERENTIATION (CALCULUS); MINERALOGY; SIGNALING; STEM CELLS;

ADIPOSE DERIVED STEM CELLS; BONE REGENERATION; FLUORAPATITES; MINERALIZATION; OSTEOGENIC DIFFERENTIATION; SIGNALING PATHWAYS; STIMULATING EFFECTS; VASCULAR ENDOTHELIAL GROWTH FACTOR;

ENDOTHELIAL CELLS;

FLUORAPATITE; VASCULOTROPIN; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR; APATITE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ADIPOSE DERIVED STEM CELL; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; TISSUE SCAFFOLD; ADIPOSE TISSUE; ADSORPTION; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; METABOLISM; STEM CELL; SURFACE PROPERTY;

ADIPOSE TISSUE; ADSORPTION; APATITES; CELL DIFFERENTIATION; CELL LINE; HUMANS; OSTEOGENESIS; STEM CELLS; SURFACE PROPERTIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84924388284     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35215     Document Type: Article

References (40)

1. Farre-Guasch E, Marti-Page C, Hernadez-Alfaro F, Klein-Nulend J, Casals N,. Buccal fat pad, an oral access source of human adipose stem cells with potential for osteochondral tissue engineering: An in vitro study. Tissue Eng Part C Methods 2010; 16: 1083-1094.
2. Panetta NJ, Gupta DM, Longaker MT,. Bone regeneration and repair. Curr Stem Cell Res Ther 2010; 5: 122-128.
3. Gimble JM, Katz AJ, Bunnell BA,. Adipose-derived stem cells for regenerative medicine. Circ Res 2007; 100: 1249-1260.
4. Murohara T,. Autologus adipose tissue as a new source of progenitor cells for therapeutic angiogenesis. J Cardiol 2009; 53: 155-163.
5. Nakagami H, Morishita R, Maeda K, Kikuchi Y, Oglihara T, Kaneda Y,. Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy. J Atheroscler Thromb 2006; 13: 77-81.
6. Zeng Q, Li X, Beck G, Balian G, Shen F,. Growth and differentiation factor-5 (GDF-5) stimulates osteogenic differentiation and increases vascular endothelial growth factor (VEGF) levels in fat-derived stromal cells in vitro. Bone 2006; 40: 374-381.
7. Baltag I, Watanabe K, Kusakari H, Taguchi N, Miyakawa O, Kobayashi M, Ito N,. Long-term changes of hydroxyapatite-coated dental implants. J Biomed Mater Res 2000; 53: 76-85.
8. Mistry S, Kundu D, Datta S, Basu D,. Comparison of bioactive glass coated and hydroxyapatite coated titanium dental implants in the human jaw bone. Australian Dent J 2011; 56: 68-75.
9. Eom TG, Jeon GR, Jeong CM, Kim YK, Kim SG, Cho IH, Cho YS, Oh JS,. Experimental study of bone response to hydroxyapatite coating implants: Bone-implant contact and removal torque test. Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 114: 411-418.
10. Fazan F, Marquis PM,. Dissolution behavior of plasma-sprayed hydroxyapatite coatings. J Mater Sci: Mater Med 2000; 11: 787-792.
11. Chen H, Sun K, Tang Z, Law RV, Mansfield JF, Czajka-Jakubowska A, Clarkson BH,. Synthesis of fluorapatite nanorods and nanowires by direct precipitation from solution. Crys Growth Des 2006; 6: 1504-1508.
12. Chen H, Tang Z, Liu J, Sun K, Chang SR, Peters MC, Mansfield JF, Czajka-Jakubowska A, Clarkson BH,. Acellular synthesis of a Human Enamel-like Microstructure. Adv Mater 2006; 18: 1846-1851.
13. Liu J, Jin TC, Chang S, Czajka-Jakubowska A, Clarkson BH,. Adhesion and growth of dental pulp stem cells (DPSCs) on enamel-like fluorapatite (FA) surfaces. J Biomed Mater Res A 2011; 96: 528-534.
14. Liu J, Jin T, Chang S, Czajka-Jakubowska A, Zhang Z, Nor J, Clarkson BH,. The effect of novel fluorapatite (FA) surfaces on osteoblast-like cell adhesion, growth and mineralization. Tissue Eng Part A 2010; 16: 2977-2986.
15. Liu J, Wang X, Jin Q, Jin T, Chang S, Zhang Z, Czajka-Jakubowska A, Giannobile W, Nor J, Clarkson BH,. The stimulation of adipose-derived stem cell differentiation and mineralization by ordered rod-like fluorapatite coatings. Biomaterials 2012; 33: 5036-5046.
16. Behr B, Tang C, Germann G, Longaker M, Quarto N,. Locally applied VEGFA increases the osteogenic healing capacity of human adipose derived stem cells by promoting osteogenic and endothelial differentiation. Stem Cells 2011; 29: 286-296.
17. Murphy WL, Simmons CA, Kaigler D, Mooney DJ,. Bone regeneration via a mineral substrate and induced angiogenesis. J Dent Res 2004; 83: 204-210.
18. Gerber HP, Vu TH, Ryan AM, Kowalski J, Werb Z, Ferrara N,. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 1999; 5: 623-628.
19. Leach JK, Kaigler D, Wang Z, Krebsbach PH, Mooney DJ,. Coating of VEGF-releasing scaffolds with bioactive glass for angiogenesis and bone regeneration. Biomaterials 2006; 27: 3249-3255.
20. Brown G, Hughes PJ, Michell RH,. Cell differentiation and proliferation-Simultaneous but independent? Exp Cell Res 2003; 10: 282-288.
21. Kim BS, Kim JS, Chung YS, Sin YW, Ryu KH, Lee J, You HK,. Growth and osteogenic differentiation of alveolar human bone marrow-derived mesenchymal stem cells on chitosan/hydroxyapatite composite fabric. J Biomed Mater Res A 2013; 101: 1550-1558.
22. Matsubara H, Hogan DE, Morgan EF, Mortlock DP, Einhorn TA, Gerstenfeld LC,. Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis. Bone 2012; 51: 168-180.
23. Lu C, Marcucio R, Miclau T,. Assessing angiogenesis during fracture healing. Iowa Orthop J 2006; 26: 17-26.
24. Jacobsen KA, Al-Aql ZS, Wan C, Fitch JL, Stapleton SN, Mason ZD, Cole RM, Gilbert SR, Clemens TL, Morgan EF, Einhorn TA, Gerstenfeld LC,. Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. J Bone Miner Res 2008; 23: 596-609.
25. Furumatsu T, Shen ZN, Kawai A, Nishida K, Manabe H, Oohashi T, Inoue H, Ninomiya Y,. Vascular endothelial growth factor principally acts as the main angiogenic factor in the early stage of human osteoblastogenesis. J Biochem 2003; 133: 633-699.
26. Mayer H, Bertram H, Lindenmaier W, Korff T, Weber H, Weich H,. Vascular endothelial growth factor (VEGF-A) expression in human mesenchymal stem cells: Autocrine and paracrine role on osteoblastic and endothelial differentiation. J Cell Biochem 2005; 95: 827-839.
27. Morabito A, De Maio E, Di Maio M, Normanno N, Perrone F,. Tyrosine kinase inhibitors of vascular endothelial growth factor receptors in clinical trials: Current status and future directions. Oncologist 2006; 11: 753-764.
28. Nakamura K, Taguchi E, Miura T, Yamamoto A, Takahashi K, Bichat F, Guilbaud N, Hasegawa K, Kubo K, Fujiwara Y, Suzuki R, Kubo K, Shibuya M, Isae T,. KRN951, a highly potent and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases, has anti-tumor activities and affects functional vascular properties. Cancer Res 2006; 66: 9134-4.
29. Goodman VL, Rock EP, Dagher R, Ramchandani RP, Abraham S, Gobburu JV, Booth BP, Verbois SL, Morse DE, Liang CY, Chidambaram N, Jiang JX, Tang S, Mahjoob K, Justice R, Pazdur R,. Approval summary: Sunitinib for the treatment of imatinib refractory or intolerant gastrointestinal stromal tumors and advanced renal cell carcinoma. Clin Cancer Res 2007; 13: 1367-1373.
30. Rossler J, Monnet Y, Farace F, Opolon P, Daudigeos-Dubus E, Bourredjem A, Vassal G, Geoerger B,. The selective VEGFR1-3 inhibitor axitinib (AG-013736) shows antitumor activity in human neuroblastoma xenografts. Int J Cancer 2001; 128: 2748-2758.
31. Zhang Y, Madhu V, Dighe AS, Irvine JN, Cui Q,. Osteogenic response of human adipose derived stem cells to BMP-6, VEGF, and combined VEGF plus BMP-6 in vitro. Growth Factors 2012; 30: 333-343.
32. Li P, Bai Y, Yin G, Pu X, Huang Z, Liao X, Chen X, Yao Y,. Synergistic and sequential effects of BMP-2, bFGF and VEGF on osteogenic differentiation of rat osteoblasts. J Bone Miner Metab. DOI: 10.1007/s00774-013-0538-6.
33. Schonmeyr BH, Soares M, Avraham T, Clavin NW, Gewalli F, Mehrara BJ,. Vascular endothelial growth factor inhibits bone morphogenetic protein 2 expression in rat mesenchymal stem cells. Tissue Eng Part A 2010; 16: 653-662.
34. Kwon TG, Zhao X, Yang Q, Li Y, Ge C, Zhao G, Franceschi RT,. Physical and functional interactions between Runx2 and HIF-1α induce vascular endothelial growth factor gene expression. J Cell Biochem 2011; 112: 3582-3593.
35. Lee KY, Peters MC, Mooney DJ,. Comparison of vascular endothelial growth factor and basic fibroblast growth factor on angio genesis in SCID mice. J Control Release 2003; 21: 49-56.
36. Wang X, Zhang Z, Chang S, Czajka-Jakubowska A, Nor J, Clarkson BH, Ni LX, Liu J,. Fluorapatite enhances mineralization of mesenchymal/endothelial co-cultures. Tissue Eng Part A 2014; 20: 12-22.
37. Hanada K, Dennis JE, Caplan AI,. Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells. J Bone Miner Res 1997; 12: 1606-1614.
38. Kim JH, Kim TH, Jin GZ, Park JH, Yun YR, Jang JH, Kim HW,. Mineralized poly(lactic acid) scaffolds loading vascular endothelial growth factor and the in vivo performance in rat subcutaneous model. J Biomed Mater Res A 2013; 101: 1447-1455.
39. Kilpadi KL, Chang PL, Bellis SL,. Hydroxylapatite binds more serum proteins, purified integrins and osteoblast precursor cells than titanium or steel. J Biomed Mater Res 2001; 57: 258-267.
40. Sawyer AA, Hennessy KM, Bellis SL,. The effect of adsorbed serum proteins, RGD and proteoglycan-binding peptides on the adhesion of mesenchymal stem cells to hydroxyapatite. Biometerials 2007; 28: 383-392.