메뉴 건너뛰기




Volumn 12, Issue 2, 2015, Pages

Open Access to Large Scale Datasets Is Needed to Translate Knowledge of Cancer Heterogeneity into Better Patient Outcomes

Author keywords

[No Author keywords available]

Indexed keywords

CANCER RESEARCH; EDITORIAL; GENE SEQUENCE; GENETIC DATABASE; GENETIC HETEROGENEITY; GENOMICS; HUMAN; RANDOMIZED CONTROLLED TRIAL (TOPIC); ACCESS TO INFORMATION; FACTUAL DATABASE; GENETIC VARIATION; GENETICS; HEALTH SERVICE; INFORMATION PROCESSING; MOLECULARLY TARGETED THERAPY; NEOPLASMS; TRANSLATING (LANGUAGE); TRANSLATIONAL RESEARCH;

EID: 84924365665     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001794     Document Type: Editorial
Times cited : (15)

References (30)
  • 1
    • 77951115122 scopus 로고    scopus 로고
    • International network of cancer genome projects
    • Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, et al. (2010) International network of cancer genome projects. Nature 464: 993–998. doi: 10.1038/nature08987 20393554
    • (2010) Nature , vol.464 , pp. 993-998
    • Hudson, T.J.1    Anderson, W.2    Artez, A.3    Barker, A.D.4    Bell, C.5
  • 2
    • 84875758730 scopus 로고    scopus 로고
    • Lessons from the cancer genome
    • Garraway LA, Lander ES, (2013) Lessons from the cancer genome. Cell 153: 17–37. doi: 10.1016/j.cell.2013.03.002 23540688
    • (2013) Cell , vol.153 , pp. 17-37
    • Garraway, L.A.1    Lander, E.S.2
  • 3
    • 77956838065 scopus 로고    scopus 로고
    • Advances in understanding cancer genomes through second-generation sequencing
    • Meyerson M, Gabriel S, Getz G, (2010) Advances in understanding cancer genomes through second-generation sequencing. Nat Rev Genet 11: 685–696. doi: 10.1038/nrg2841 20847746
    • (2010) Nat Rev Genet , vol.11 , pp. 685-696
    • Meyerson, M.1    Gabriel, S.2    Getz, G.3
  • 4
    • 84907067643 scopus 로고    scopus 로고
    • Expanding the computational toolbox for mining cancer genomes
    • Ding L, Wendl MC, McMichael JF, Raphael BJ, (2014) Expanding the computational toolbox for mining cancer genomes. Nat Rev Genet 15: 556–570. doi: 10.1038/nrg3767 25001846
    • (2014) Nat Rev Genet , vol.15 , pp. 556-570
    • Ding, L.1    Wendl, M.C.2    McMichael, J.F.3    Raphael, B.J.4
  • 5
    • 84863652136 scopus 로고    scopus 로고
    • Circumventing cancer drug resistance in the era of personalized medicine
    • Garraway LA, Jänne PA, (2012) Circumventing cancer drug resistance in the era of personalized medicine. Cancer Discov 2: 214–226. doi: 10.1158/2159-8290.CD-12-0012 22585993
    • (2012) Cancer Discov , vol.2 , pp. 214-226
    • Garraway, L.A.1    Jänne, P.A.2
  • 6
    • 84884365015 scopus 로고    scopus 로고
    • The causes and consequences of genetic heterogeneity in cancer evolution
    • Burrell RA, McGranahan N, Bartek J, Swanton C, (2013) The causes and consequences of genetic heterogeneity in cancer evolution. Nature 501: 338–345. doi: 10.1038/nature12625 24048066
    • (2013) Nature , vol.501 , pp. 338-345
    • Burrell, R.A.1    McGranahan, N.2    Bartek, J.3    Swanton, C.4
  • 7
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, et al. (2012) Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 366: 883–892. doi: 10.1056/NEJMoa1113205 22397650
    • (2012) N Engl J Med , vol.366 , pp. 883-892
    • Gerlinger, M.1    Rowan, A.J.2    Horswell, S.3    Larkin, J.4    Endesfelder, D.5
  • 8
    • 84885092663 scopus 로고    scopus 로고
    • Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling
    • Bashashati A, Ha G, Tone A, Ding J, Prentice LM, et al. (2013) Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling. J Pathol 231: 21–34. doi: 10.1002/path.4230 23780408
    • (2013) J Pathol , vol.231 , pp. 21-34
    • Bashashati, A.1    Ha, G.2    Tone, A.3    Ding, J.4    Prentice, L.M.5
  • 9
    • 84907855592 scopus 로고    scopus 로고
    • Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
    • De Bruin EC, McGranahan N, Mitter R, Salm M, Wedge DC, et al. (2014) Spatial and temporal diversity in genomic instability processes defines lung cancer evolution. Science (80-) 346: 251–256.
    • (2014) Science , vol.346 , Issue.80 , pp. 251-256
    • De Bruin, E.C.1    McGranahan, N.2    Mitter, R.3    Salm, M.4    Wedge, D.C.5
  • 10
    • 84914112343 scopus 로고    scopus 로고
    • Tumour heterogeneity and the evolution of polyclonal drug resistance
    • Burrell RA, Swanton C, (2014) Tumour heterogeneity and the evolution of polyclonal drug resistance. Mol Oncol 8: 1095–1111. doi: 10.1016/j.molonc.2014.06.005 25087573
    • (2014) Mol Oncol , vol.8 , pp. 1095-1111
    • Burrell, R.A.1    Swanton, C.2
  • 11
    • 84901318643 scopus 로고    scopus 로고
    • Phylogenetic quantification of intra-tumour heterogeneity
    • Schwarz RF, Trinh A, Sipos B, Brenton JD, Goldman N, et al. (2014) Phylogenetic quantification of intra-tumour heterogeneity. PLoS Comput Biol 10: e1003535. doi: 10.1371/journal.pcbi.1003535 24743184
    • (2014) PLoS Comput Biol , vol.10 , pp. 1003535
    • Schwarz, R.F.1    Trinh, A.2    Sipos, B.3    Brenton, J.D.4    Goldman, N.5
  • 12
    • 84924359778 scopus 로고    scopus 로고
    • Spatial and Temporal Heterogeneity in High-Grade Serous Ovarian Cancer: A Phylogenetic Reconstruction
    • Schwarz RF, Ng CKY, Cooke SL, Newman S, Temple J, Piskorz AM, et al. (2015) Spatial and Temporal Heterogeneity in High-Grade Serous Ovarian Cancer: A Phylogenetic Reconstruction. PLoS Med 12: e1001789. doi: 10.1371/journal.pmed.1001789
    • (2015) PLoS Med , vol.12 , pp. 1001789
    • Schwarz, R.F.1    Ng, C.K.Y.2    Cooke, S.L.3    Newman, S.4    Temple, J.5    Piskorz, A.M.6
  • 14
    • 84902460514 scopus 로고    scopus 로고
    • Risk prediction for late-stage ovarian cancer by meta-analysis of 1525 patient samples
    • Riester M, Wei W, Waldron L, Culhane AC, Trippa L, et al. (2014) Risk prediction for late-stage ovarian cancer by meta-analysis of 1525 patient samples. J Natl Cancer Inst 106.
    • (2014) J Natl Cancer Inst , vol.106
    • Riester, M.1    Wei, W.2    Waldron, L.3    Culhane, A.C.4    Trippa, L.5
  • 15
    • 84924388105 scopus 로고    scopus 로고
    • Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from the Cancer Genome Atlas
    • Mroz EA, Tward AM, Hammon RJ, Ren Y, Rocco JW, (2015) Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from the Cancer Genome Atlas. PLoS Med 12: e1001786. doi: 10.1371/journal.pmed.1001786
    • (2015) PLoS Med , vol.12 , pp. 1001786
    • Mroz, E.A.1    Tward, A.M.2    Hammon, R.J.3    Ren, Y.4    Rocco, J.W.5
  • 16
    • 80052158097 scopus 로고    scopus 로고
    • The mutational landscape of head and neck squamous cell carcinoma
    • Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, et al. (2011) The mutational landscape of head and neck squamous cell carcinoma. Science 333: 1157–1160. doi: 10.1126/science.1208130 21798893
    • (2011) Science , vol.333 , pp. 1157-1160
    • Stransky, N.1    Egloff, A.M.2    Tward, A.D.3    Kostic, A.D.4    Cibulskis, K.5
  • 17
    • 84873412457 scopus 로고    scopus 로고
    • MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma
    • Mroz EA, Rocco JW, (2013) MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma. Oral Oncol 49: 211–215. doi: 10.1016/j.oraloncology.2012.09.007 23079694
    • (2013) Oral Oncol , vol.49 , pp. 211-215
    • Mroz, E.A.1    Rocco, J.W.2
  • 18
    • 84902148239 scopus 로고    scopus 로고
    • Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
    • Van Allen EM, Wagle N, Stojanov P, Perrin DL, Cibulskis K, et al. (2014) Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. Nat Med 20: 682–688. doi: 10.1038/nm.3559 24836576
    • (2014) Nat Med , vol.20 , pp. 682-688
    • Van Allen, E.M.1    Wagle, N.2    Stojanov, P.3    Perrin, D.L.4    Cibulskis, K.5
  • 19
    • 84924401681 scopus 로고    scopus 로고
    • Sage Bionetworks (2015) ICGC-TCGA DREAM Somatic Mutation Calling Challenge—Tumor Heterogeneity & Evolution. https://www.synapse.org/#!Synapse:syn2813581. Accessed 15 January 2015.
  • 20
    • 79953766940 scopus 로고    scopus 로고
    • Tumour evolution inferred by single-cell sequencing
    • Navin N, Kendall J, Troge J, Andrews P, Rodgers L, et al. (2011) Tumour evolution inferred by single-cell sequencing. Nature 472: 90–94. doi: 10.1038/nature09807 21399628
    • (2011) Nature , vol.472 , pp. 90-94
    • Navin, N.1    Kendall, J.2    Troge, J.3    Andrews, P.4    Rodgers, L.5
  • 21
    • 85027920141 scopus 로고    scopus 로고
    • Cancer genomics: one cell at a time
    • Navin NE, (2014) Cancer genomics: one cell at a time. Genome Biol 15: 452. doi: 10.1186/s13059-014-0452-9 25222669
    • (2014) Genome Biol , vol.15 , pp. 452
    • Navin, N.E.1
  • 22
    • 84902668801 scopus 로고    scopus 로고
    • Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
    • Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, et al. (2014) Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science 344: 1396–1401. doi: 10.1126/science.1254257 24925914
    • (2014) Science , vol.344 , pp. 1396-1401
    • Patel, A.P.1    Tirosh, I.2    Trombetta, J.J.3    Shalek, A.K.4    Gillespie, S.M.5
  • 23
    • 84897090228 scopus 로고    scopus 로고
    • Highly multiplexed subcellular RNA sequencing in situ
    • Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Yang JL, et al. (2014) Highly multiplexed subcellular RNA sequencing in situ. Science 343: 1360–1363. doi: 10.1126/science.1250212 24578530
    • (2014) Science , vol.343 , pp. 1360-1363
    • Lee, J.H.1    Daugharthy, E.R.2    Scheiman, J.3    Kalhor, R.4    Yang, J.L.5
  • 24
    • 84883459000 scopus 로고    scopus 로고
    • In situ sequencing for RNA analysis in preserved tissue and cells
    • Ke R, Mignardi M, Pacureanu A, Svedlund J, Botling J, et al. (2013) In situ sequencing for RNA analysis in preserved tissue and cells. Nat Methods 10: 857–860. doi: 10.1038/nmeth.2563 23852452
    • (2013) Nat Methods , vol.10 , pp. 857-860
    • Ke, R.1    Mignardi, M.2    Pacureanu, A.3    Svedlund, J.4    Botling, J.5
  • 25
    • 84897402237 scopus 로고    scopus 로고
    • Next-gen immunohistochemistry
    • Rimm DL, (2014) Next-gen immunohistochemistry. Nat Methods 11: 381–383. doi: 10.1038/nmeth.2896 24681723
    • (2014) Nat Methods , vol.11 , pp. 381-383
    • Rimm, D.L.1
  • 26
    • 84898402897 scopus 로고    scopus 로고
    • Multiplexed ion beam imaging of human breast tumors
    • Angelo M, Bendall SC, Finck R, Hale MB, Hitzman C, et al. (2014) Multiplexed ion beam imaging of human breast tumors. Nat Med 20: 436–442. doi: 10.1038/nm.3488 24584119
    • (2014) Nat Med , vol.20 , pp. 436-442
    • Angelo, M.1    Bendall, S.C.2    Finck, R.3    Hale, M.B.4    Hitzman, C.5
  • 27
    • 84897954497 scopus 로고    scopus 로고
    • Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
    • Giesen C, Wang HAO, Schapiro D, Zivanovic N, Jacobs A, et al. (2014) Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry. Nat Methods 11: 417–422. doi: 10.1038/nmeth.2869 24584193
    • (2014) Nat Methods , vol.11 , pp. 417-422
    • Giesen, C.1    Wang, H.A.O.2    Schapiro, D.3    Zivanovic, N.4    Jacobs, A.5
  • 28
    • 84880357794 scopus 로고    scopus 로고
    • Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue
    • Gerdes MJ, Sevinsky CJ, Sood A, Adak S, Bello MO, et al. (2013) Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue. Proc Natl Acad Sci U S A 110: 11982–11987. doi: 10.1073/pnas.1300136110 23818604
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 11982-11987
    • Gerdes, M.J.1    Sevinsky, C.J.2    Sood, A.3    Adak, S.4    Bello, M.O.5
  • 29
    • 70449420123 scopus 로고    scopus 로고
    • Use of archived specimens in evaluation of prognostic and predictive biomarkers
    • Simon RM, Paik S, Hayes DF, (2009) Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst 101: 1446–1452. doi: 10.1093/jnci/djp335 19815849
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1446-1452
    • Simon, R.M.1    Paik, S.2    Hayes, D.F.3
  • 30
    • 80054882456 scopus 로고    scopus 로고
    • Re: Use of archived specimens in evaluation of prognostic and predictive biomarkers
    • Ahern TP, Hankinson SE, (2011) Re: Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst 103: 1558–1559; author reply 1559–1560. doi: 10.1093/jnci/djr327 21917608
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1558-1559
    • Ahern, T.P.1    Hankinson, S.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.