Intra-tumor Genetic Heterogeneity and Mortality in Head and Neck Cancer: Analysis of Data from The Cancer Genome Atlas

PLoS Medicine

Volumn 12, Issue 2, 2015, Pages

  Mroz, Edmund A ^a,d   Tward, Aaron M ^b,c,e   Hammon, Rebecca J ^b   Ren, Yin ^b   Rocco, James W ^a,b,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; DNA;

AGE; ARTICLE; CANCER MORTALITY; CANCER STAGING; CANCER THERAPY; CLINICAL TRIAL (TOPIC); DATA ANALYSIS; DEATH; DISEASE ASSOCIATION; FOLLOW UP; GENE MUTATION; GENETIC HETEROGENEITY; HEAD AND NECK CANCER; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; LYMPH NODE; OROPHARYNX CANCER; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PROGNOSTIC ASSESSMENT; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SMOKING; SQUAMOUS CELL CARCINOMA; WART VIRUS; AGED; ALLELE; CLINICAL TRIAL; DNA SEQUENCE; EXOME; FEMALE; GENETIC VARIATION; GENETICS; HEAD AND NECK TUMOR; MALE; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; MUTATION; OROPHARYNX TUMOR; PAPILLOMAVIRIDAE; PROPORTIONAL HAZARDS MODEL; VALIDATION STUDY; VIROLOGY;

AGED; ALLELES; CARCINOMA, SQUAMOUS CELL; DNA, NEOPLASM; EXOME; FEMALE; GENETIC VARIATION; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; MUTATION; OROPHARYNGEAL NEOPLASMS; PAPILLOMAVIRIDAE; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; SEQUENCE ANALYSIS, DNA;

EID: 84924388105     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001786     Document Type: Article

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