Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 10, 2015, Pages 2935-2941

  Shen, Yiguo ^a,e   Ge, Woo Ping ^b,f   Li, Yulong ^c,g   Hirano, Arisa ^a   Lee, Hsien Yang ^a   Rohlmann, Astrid ^b   Missler, Markus ^b   Tsien, Richard W ^c,h   Jan, Lily Yeh ^b   Fu, Ying Hui ^a   Ptáček, Louis J ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY   (United States)

^d UNIVERSITY OF MÜNSTER   (Germany)

^e NVIGEN Inc   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g Tsinghua University   (China)

^h NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dyskinesia; Exocytosis; Neurological disease; Paroxysmal

Indexed keywords

CELL PROTEIN; MUTANT PROTEIN; NEUROTRANSMITTER; PAROXYSMAL NONKINESIGENIC DYSKINESIA PROTEIN; RAB3 INTERACTING MOLECULE 1 PROTEIN; RAB3 INTERACTING MOLECULE 2 PROTEIN; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER; ABC TRANSPORTER; ABCA4 PROTEIN, MOUSE; MUSCLE PROTEIN; MYOFIBRILLOGENESIS REGULATOR-1, MOUSE; PROTEIN BINDING;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHANNELOPATHY; CONTROLLED STUDY; DYSKINESIA; EXOCYTOSIS; GENE OVEREXPRESSION; KNOCKOUT MOUSE; MOUSE; NEUROTRANSMITTER RELEASE; NONHUMAN; PAROXYSMAL NONKINESIGENIC DYSKINESIA; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PYRAMIDAL NERVE CELL; SYNAPSE; SYNAPSE VESICLE; WILD TYPE; ANIMAL; CHOREA; GENETICS; METABOLISM; PHYSIOLOGY;

MUS;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHOREA; EXOCYTOSIS; MICE; MICE, KNOCKOUT; MUSCLE PROTEINS; PROTEIN BINDING; SYNAPTIC VESICLES;

EID: 84924359832     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1501364112     Document Type: Article

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