Methotrexatehow does it really work?

Nature Reviews Rheumatology

Volumn 6, Issue 3, 2010, Pages 175-178

  Chan, Edwin S L ^a   Cronstein, Bruce N ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEAZAADENOSINE; ADENOSINE; CAFFEINE; DIHYDROFOLATE REDUCTASE; FOLIC ACID; FOLINIC ACID; INTERLEUKIN 1; LYMPHOTOXIN; METHOTREXATE; POLYAMINE; PTEROPTIN; RHEUMATOID FACTOR; TUMOR NECROSIS FACTOR; ANTIINFLAMMATORY AGENT; ANTIRHEUMATIC AGENT; FOLIC ACID ANTAGONIST;

ANTIINFLAMMATORY ACTIVITY; CELL CYCLE ARREST; CELL SECRETION; CHEMOTAXIS; COFFEE; CYTOKINE PRODUCTION; DRUG ANTAGONISM; DRUG EFFICACY; DRUG INHIBITION; DRUG UPTAKE; ENZYME INHIBITION; FOLATE ANTAGONISM; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; KNEE ARTHRITIS; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER PROTECTION; LIVER TOXICITY; LOW DRUG DOSE; NEUTROPHIL; NONHUMAN; NOTE; POLYAMINE INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; PROTEIN URINE LEVEL; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS; RHEUMATOID NODULE; ARTICLE; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECT; METABOLISM;

ANTI-INFLAMMATORY AGENTS; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FOLIC ACID ANTAGONISTS; HUMANS; METHOTREXATE; POLYAMINES;

EID: 77749277178     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2010.5     Document Type: Note

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