Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 10, 2015, Pages 3056-3061

  Krishnaswamy, Jayendra Kumar ^a   Singh, Arpita ^a   Gowthaman, Uthaman ^a   Wu, Renee ^a   Gorrepati, Pavane ^a   Nascimento, Manuela Sales ^a   Gallman, Antonia ^a   Liu, Dong ^a   Rhebergen, Anne Marie ^a   Calabro, Samuele ^a   Xu, Lan ^a   Ranney, Patricia ^a   Srivastava, Anuj ^b   Ranson, Matthew ^c   Gorham, James D ^c   McCaw, Zachary ^d   Kleeberger, Steven R ^d   Heinz, Leonhard X ^e   Müller, André C ^e   Bennett, Keiryn L ^e   Superti Furga, Giulio ^e   Henao Mejia, Jorge ^f   Sutterwala, Fayyaz S ^g   Williams, Adam ^h   Flavell, Richard A ^a   Eisenbarth, Stephanie C ^a   more..

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JACKSON LABORATORY   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g UNIVERSITY OF IOWA   (United States)

^h UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

C3H HeJ; CDC42; Dendritic cell; DOCK8; NLRP10

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR 8; INFLAMMASOME; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; NLR FAMILY PYRIN DOMAIN CONTAINING 10; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; T LYMPHOCYTE RECEPTOR; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; CARRIER PROTEIN; DOCK8 PROTEIN, MOUSE; NLRP10 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CELL MIGRATION; CELL POPULATION; CONTROLLED STUDY; CYTOKINESIS; CYTOSKELETON; DENDRITIC CELL; ENZYME MECHANISM; EXOME; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; HUMAN; IMMUNE DEFICIENCY; IMMUNE RESPONSE; KNOCKOUT MOUSE; LEUKOCYTE; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; PATTERN RECOGNITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEOMICS; SPONTANEOUS MUTATION; T LYMPHOCYTE ACTIVATION; ANIMAL; C3H MOUSE; CELL MOTION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; POINT MUTATION;

MURINAE; MUS; RUMEX;

ANIMALS; CARRIER PROTEINS; CELL MOVEMENT; DENDRITIC CELLS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; POINT MUTATION;

EID: 84924308188     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1501554112     Document Type: Article

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