Evolutionarily emerged G tracts between the polypyrimidine tract and 3' AG are splicing silencers enriched in genes involved in cancer

BMC Genomics

Volumn 15, Issue 1, 2014, Pages

  Sohail, Muhammad ^a   Cao, Wenguang ^a   Mahmood, Niaz ^b   Myschyshyn, Mike ^a   Hong, Say Pham ^a   Xie, Jiuyong ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

3' splice site; Alternative splicing; Cancer; Evolution; G tract

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN F; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H; POLYPYRIMIDINE TRACT BINDING PROTEIN; UNCLASSIFIED DRUG; RNA SPLICING;

ALTERNATIVE RNA SPLICING; ARTICLE; BIOINFORMATICS; CARRE1 GENE; CONTROLLED STUDY; EXON; GENE; GENE SILENCING; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC VARIABILITY; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN GENOME; INTRON; MALIGNANT NEOPLASTIC DISEASE; MAMMAL; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE MOTIF; REGULATORY RNA SEQUENCE; RNA INTERFERENCE; RNA PROCESSING; SPECIES COMPARISON; VERTEBRATE; ANIMAL; CONSENSUS SEQUENCE; GC RICH SEQUENCE; GENETICS; GENOMICS; MUTATION; NEOPLASM; NUCLEOTIDE SEQUENCE; RNA SPLICING; TUMOR GENE;

MAMMALIA; VERTEBRATA;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; CONSENSUS SEQUENCE; EVOLUTION, MOLECULAR; GC RICH SEQUENCE; GENE SILENCING; GENES, NEOPLASM; GENOMICS; HUMANS; MUTATION; NEOPLASMS; RNA SPLICE SITES; RNA SPLICING;

EID: 84924292739     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-15-1143     Document Type: Article

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