Antiproliferative activity and induction of apoptosis by Annona muricata (Annonaceae) extract on human cancer cells

BMC Complementary and Alternative Medicine

Volumn 14, Issue 1, 2014, Pages

  Pieme, Anatole ^a,b   Kumar, Guru ^b   Dongmo, Sylviane ^c   Moukette, Moukette ^a   Boyoum, Fekam ^a   Ngogang, Yonkeu ^a   Saxena, Kumar ^b  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^c UNIVERSITY OF BUEA   (Cameroon)

Author keywords

A. muricata; Antiproliferative; Apoptosis; Cell cycle; Membrane mitochondrial potential

Indexed keywords

ANNONA MURICATA EXTRACT; ANTINEOPLASTIC AGENT; FLAVONOID; FLAVONOL DERIVATIVE; PHENOL DERIVATIVE; REACTIVE OXYGEN METABOLITE; PLANT EXTRACT;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; G1 PHASE CELL CYCLE CHECKPOINT; HL 60 CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; AFRICA; ANNONA; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; LEUKEMIA, PROMYELOCYTIC, ACUTE; METABOLISM; MITOCHONDRION; PHYTOTHERAPY;

AFRICA; ANNONA; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LEUKEMIA, PROMYELOCYTIC, ACUTE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES;

EID: 84924291818     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-516     Document Type: Article

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