Increase of miR-199a-5p by protoporphyrin IX, a photocatalyzer, directly inhibits E2F3, sensitizing mesenchymal tumor cells to anti-cancer agents

Oncotarget

Volumn 6, Issue 6, 2015, Pages 3918-3931

  Lee, Jung Min ^a   Heo, Mi Jeong ^a   Lee, Chan Gyu ^a   Yang, Yoon Mee ^a   Kim, Sang Geon ^a  

^a Seoul National University   (South Korea)

Author keywords

Chemotherapeutic agent; E2F3; Hepatocellular carcinoma; MiR 199a 5p; Protoporphyrin IX

Indexed keywords

CISPLATIN; DOXORUBICIN; MICRORNA; MICRORNA 199A 5P; PROTOPORPHYRIN; PROTOPORPHYRIN TIN; TRANSCRIPTION FACTOR E2F3; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; E2F3 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MIRN199 MICRORNA, HUMAN; PHOTOSENSITIZING AGENT;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER SIZE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG RESPONSE; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LIVER CANCER CELL LINE; LIVER CELL CARCINOMA; MESENCHYME CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR INVASION; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BIOSYNTHESIS; CARCINOMA, HEPATOCELLULAR; CELL MOTION; DRUG EFFECTS; DRUG SCREENING; GENETIC TRANSFECTION; GENETICS; HEP-G2 CELL LINE; LIVER NEOPLASMS; MESENCHYMAL STROMA CELL; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PATHOLOGY; RANDOMIZATION;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CELL MOVEMENT; DRUG SYNERGISM; E2F3 TRANSCRIPTION FACTOR; HEP G2 CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER NEOPLASMS; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; MOLECULAR SEQUENCE DATA; PHOTOSENSITIZING AGENTS; PROTOPORPHYRINS; RANDOM ALLOCATION; TRANSFECTION; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84924268719     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2928     Document Type: Article

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