The deoxycholic acid targets miRNA-dependent CAC1 gene expression in multidrug resistance of human colorectal cancer

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 12, 2012, Pages 2321-2332

  Kong, Ying ^a   Bai, Pei Song ^a   Sun, Hong ^a   Nan, Ke Jun ^a   Chen, Nan Zheng ^a   Qi, Xiao Gai ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

CAC1; Colorectal cancer; Deoxycholic acid; miR 199a 5p; Multidrug resistance

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE 2; DEOXYCHOLIC ACID; DOXORUBICIN; MICRORNA; MIR 199A 5P; PROTEIN CAC1; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL CULTURE; CELL CYCLE ARREST; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; MALE; MICROARRAY ANALYSIS; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PROTEIN EXPRESSION; REPORTER GENE; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

3' UNTRANSLATED REGIONS; ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BASE SEQUENCE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL NEOPLASMS; CULLIN PROTEINS; DEOXYCHOLIC ACID; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; MIDDLE AGED; RNA INTERFERENCE; TRANSCRIPTOME; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84867742919     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.08.006     Document Type: Article

References (20)

1. D.F. Altomare, M. Di Lena, and S. Giuratrabocchetta MicroRNA: future perspectives in colorectal cancer Colorectal Disease 14 2012 133 134
2. J.C. Barrett Mechanisms of multistep carcinogenesis and carcinogen risk assessment Environmental Health Perspectives 100 1993 9 20
3. C. Bernstein, H. Holubec, A.K. Bhattacharyya, H. Nguyen, C.M. Payne, and B. Zaitlin Carcinogenicity of deoxycholate, a secondary bile acid Archives of Toxicology 85 2011 863 871
4. G.A. Calin, and C.M. Croce MicroRNA-cancer connection: the beginning of a new tale Cancer Research 66 2006 7390 7394
5. C.Z. Chen MicroRNAs as oncogenes and tumor suppressors New England Journal of Medicine 353 2005 1768 1771
6. H.H. Cheung, A.J. Davis, T.L. Lee, A.L. Pang, S. Nagrani, and O.M. Rennert Methylation of an intronic region regulates miR-199a in testicular tumor malignancy Oncogene 30 2011 3404 3415
7. Q. Duan, X. Wang, W. Gong, L. Ni, C. Chen, and X. He ER stress negatively modulates the expression of the miR-199a/214 cluster to regulates tumor survival and progression in human hepatocellular cancer PLoS ONE 7 2012 e31518
8. L. Gramantieri, M. Ferracin, F. Fornari, A. Veronese, S. Sabbioni, and C.G. Liu Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma Cancer Research 67 2007 6092 6099
9. R.I. Gregory, and R. Shiekhattar MicroRNA biogenesis and cancer Cancer Research 65 2005 3509 3512
10. Y. Han, T. Haraguchi, S. Iwanaga, H. Tomotake, Y. Okazaki, and S. Mineo Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer Journal of Agricultural and Food Chemistry 57 2009 8587 8590
11. R. Hummel, T. Wang, D.I. Watson, M.Z. Michael, M. Van der Hoek, and J. Haier Chemotherapy-induced modification of microRNA expression in esophageal cancer Oncology Reports 26 2011 1011 1017
12. Y. Kong, K. Nan, and Y. Yin Identification and characterization of CAC1 as a novel CDK2-associated cullin Cell Cycle 8 2009 3544 3553
13. Y. Kong, P.S. Bai, H. Sun, and K.J. Nan Expression of the newly identified gene CAC1 in the hippocampus of Alzheimer's disease patients Journal of Molecular Neuroscience 47 2012 207 218
14. C. Liu, and D.G. Tang MicroRNA regulation of cancer stem cells Cancer Research 71 2011 5950 5954
15. F.M. Nagengast, M.J. Grubben, and I.P. van Munster Role of bile acids in colorectal carcinogenesis European Journal of Cancer 31 1995 1067 1070
16. K. Sakurai, C. Furukawa, T. Haraguchi, K. Inada, K. Shiogama, and T. Tagawa MicroRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feedback loop in a variety of human cancers Cancer Research 71 2011 1680 1689
17. T. Schepeler, J.T. Reinert, M.S. Ostenfeld, L.L. Christensen, A.N. Silahtaroglu, and L. Dyrskjot Diagnostic and prognostic microRNAs in stage II colon cancer Cancer Research 68 2008 6416 6424
18. Q. Shen, V.R. Cicinnati, X. Zhang, S. Iacob, F. Weber, and G.C. Sotiropoulos Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion Molecular Cancer 9 2010 227
19. W.K. Wu, P.T. Law, C.W. Lee, C.H. Cho, D. Fan, and K. Wu MicroRNA in colorectal cancer: from benchtop to bedside Carcinogenesis 32 2011 247 253
20. R. Zarate, V. Boni, E. Bandres, and J. Garcia-Foncillas MiRNAs and LincRNAs: could they be considered as biomarkers in colorectal cancer International Journal of Molecular Sciences 13 2012 840 865