Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth

Breast Cancer Research

Volumn 16, Issue 1, 2014, Pages

  Izzo, Franco ^a   Mercogliano, Florencia ^a   Venturutti, Leandro ^a   Tkach, Mercedes ^a   Inurrigarro, Gloria ^b   Schillaci, Roxana ^a   Cerchietti, Leandro ^c   Elizalde, Patricia V ^a   Proietti, Cecilia J ^a  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b Sanatorio Mater Dei   (Argentina)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A2; GESTAGEN; MESSENGER RNA; PROGESTERONE RECEPTOR; PROTEASOME; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR GATA 3; ESTROGEN RECEPTOR; GATA3 PROTEIN, HUMAN; GATA3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER PROGNOSIS; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BREAST TUMOR; EXPERIMENTAL MAMMARY NEOPLASM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CYCLIN A2; DOWN-REGULATION; FEMALE; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MICE; PHOSPHORYLATION; PROGESTINS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE;

EID: 84924266522     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/s13058-014-0491-x     Document Type: Article

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