Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Adomas, Aleksandra B ^a   Grimm, Sara A ^a   Malone, Christine ^a   Takaku, Motoki ^a   Sims, Jennifer K ^a   Wade, Paul A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Breast cancer; ChIP seq; GATA3; Mutation; Transcription factor

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYCLOHEXIMIDE; ESTRADIOL; FULVESTRANT; INITIATION FACTOR; PROTEASOME INHIBITOR; TRANSCRIPTION FACTOR GATA 3; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA, HUMAN; FOXA1 PROTEIN, HUMAN; GATA3 PROTEIN, HUMAN; HEPATOCYTE NUCLEAR FACTOR 3ALPHA;

AFFINITY CHROMATOGRAPHY; ARTICLE; BREAST TUMOR; CANCER CELL CULTURE; CELL FRACTIONATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING; FRAMESHIFT MUTATION; GATA3 GENE; GEL MOBILITY SHIFT ASSAY; GENE LOCATION; GENE MUTATION; GENETIC ASSOCIATION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN STABILITY; TRANSCRIPTION REGULATION; WILD TYPE; BREAST NEOPLASMS; DRUG EFFECTS; FEMALE; GENETIC TRANSCRIPTION; GENETICS; MCF 7 CELL LINE; METABOLISM; MUTATION; PATHOLOGY;

BREAST NEOPLASMS; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; GATA3 TRANSCRIPTION FACTOR; HEPATOCYTE NUCLEAR FACTOR 3-ALPHA; HUMANS; MCF-7 CELLS; MUTATION; PROTEIN STABILITY; TRANSCRIPTION, GENETIC;

EID: 84899911813     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-278     Document Type: Article

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