-
2
-
-
0035909930
-
Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease
-
Aslan M. Ryan T.M. Adler B. Townes T.M. Parks D.A. Thompson J.A. Tousson A. Gladwin M.T. Patel R.P. Tarpey M.M. Batinic-Haberle I. White C.R. Freeman B.A. 2001 Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease. Proceedings of the National Academy of Science of the United States of America, 98, 15215 15220.
-
(2001)
Proceedings of the National Academy of Science of the United States of America
, vol.98
, pp. 15215-15220
-
-
Aslan, M.1
Ryan, T.M.2
Adler, B.3
Townes, T.M.4
Parks, D.A.5
Thompson, J.A.6
Tousson, A.7
Gladwin, M.T.8
Patel, R.P.9
Tarpey, M.M.10
Batinic-Haberle, I.11
White, C.R.12
Freeman, B.A.13
-
3
-
-
14244257951
-
Pulmonary hypertension in sickle cell disease
-
Ataga K.I. Sood N. De Gent G. Kelly E. Henderson A.G. Jones S. Strayhorn D. Lail A. Lieff S. Orringer E.P. 2004a Pulmonary hypertension in sickle cell disease. American Journal of Medicine, 117, 665 669.
-
(2004)
American Journal of Medicine
, vol.117
, pp. 665-669
-
-
Ataga, K.I.1
Sood, N.2
De Gent, G.3
Kelly, E.4
Henderson, A.G.5
Jones, S.6
Strayhorn, D.7
Lail, A.8
Lieff, S.9
Orringer, E.P.10
-
4
-
-
26444480407
-
Efficacy and safety of the Gardos channel inhibitor, ICA-17043, in patients with sickle cell anemia
-
Ataga K.I. DeCastro L.M. Swerdlow P. Saunthararajah Y. Smith W. 2004b Efficacy and safety of the Gardos channel inhibitor, ICA-17043, in patients with sickle cell anemia. Blood, 104, 103a.
-
(2004)
Blood
, vol.104
-
-
Ataga, K.I.1
Decastro, L.M.2
Swerdlow, P.3
Saunthararajah, Y.4
Smith, W.5
-
5
-
-
0141701988
-
Hydroxyurea downregulates endothelin-1 gene expression and upregulates ICAM-1 gene expression in cultured human endothelial cells
-
Brun M. Bourdoulous S. Couraud P.O. Elion J. Krishnamoorthy R. Lapoumeroulie C. 2003 Hydroxyurea downregulates endothelin-1 gene expression and upregulates ICAM-1 gene expression in cultured human endothelial cells. The Pharmacogenomics Journal, 3, 215 226.
-
(2003)
The Pharmacogenomics Journal
, vol.3
, pp. 215-226
-
-
Brun, M.1
Bourdoulous, S.2
Couraud, P.O.3
Elion, J.4
Krishnamoorthy, R.5
Lapoumeroulie, C.6
-
6
-
-
0030853711
-
Pathogenesis and treatment of sickle cell disease
-
Bunn H.F. 1997 Pathogenesis and treatment of sickle cell disease. New England Journal Medicine, 337, 762 769.
-
(1997)
New England Journal Medicine
, vol.337
, pp. 762-769
-
-
Bunn, H.F.1
-
7
-
-
0028234283
-
The acute chest syndrome in sickle cell disease: Incidence and risk factors
-
Castro O. Brambilla D.J. Thorington B. Reindorf C.A. Scott R.B. Gillette P. Vera J.C. Levy P.S. 1994 The acute chest syndrome in sickle cell disease: incidence and risk factors. Blood, 84, 643 649.
-
(1994)
Blood
, vol.84
, pp. 643-649
-
-
Castro, O.1
Brambilla, D.J.2
Thorington, B.3
Reindorf, C.A.4
Scott, R.B.5
Gillette, P.6
Vera, J.C.7
Levy, P.S.8
-
8
-
-
0037441758
-
Pulmonary hypertension in sickle cell disease: Cardiac catheterization results and survival
-
Castro O. Hoque M. Brown B.D. 2003 Pulmonary hypertension in sickle cell disease: cardiac catheterization results and survival. Blood, 15, 1257 1261.
-
(2003)
Blood
, vol.15
, pp. 1257-1261
-
-
Castro, O.1
Hoque, M.2
Brown, B.D.3
-
9
-
-
0029025475
-
Multicenter study of hydroxyurea in sickle cell anemia: Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia
-
Charache S. Terrin M.L. Moore R.D. Dover G.J. Barton F.B. Erkert S.V. McMahon R.P. Bonds D.R. 1995 Multicenter study of hydroxyurea in sickle cell anemia: effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. New England Journal of Medicine, 332, 1317 1322.
-
(1995)
New England Journal of Medicine
, vol.332
, pp. 1317-1322
-
-
Charache, S.1
Terrin, M.L.2
Moore, R.D.3
Dover, G.J.4
Barton, F.B.5
Erkert, S.V.6
McMahon, R.P.7
Bonds, D.R.8
-
10
-
-
0020373126
-
Pulmonary hypertension and cor pulmonale in the sickle hemoglobinopathies
-
Collins F.S. Orringer E.P. 1982 Pulmonary hypertension and cor pulmonale in the sickle hemoglobinopathies. American Journal of Medicine, 73, 814 821.
-
(1982)
American Journal of Medicine
, vol.73
, pp. 814-821
-
-
Collins, F.S.1
Orringer, E.P.2
-
11
-
-
0036175090
-
Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease
-
Gladwin M.T. Shelhamer J.H. Ognibene F.P. Pease-Fye M.E. Nichols J.S. Link B. Patel D.B. Jankowski M.A. Pannell L.K. Schechter A.N. Rodgers G.P. 2002 Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease. British Journal of Haematology, 116, 436 444.
-
(2002)
British Journal of Haematology
, vol.116
, pp. 436-444
-
-
Gladwin, M.T.1
Shelhamer, J.H.2
Ognibene, F.P.3
Pease-Fye, M.E.4
Nichols, J.S.5
Link, B.6
Patel, D.B.7
Jankowski, M.A.8
Pannell, L.K.9
Schechter, A.N.10
Rodgers, G.P.11
-
12
-
-
10744233940
-
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
-
Gladwin M.T. Sachdev V. Jison M.L. Shizukuda Y. Plehn J.F. Minter K. Brown B. Coles W.A. Nichols J.S. Ernst I. Hunter L.A. Blackwelder W.C. Schechter A.N. Rodgers G.P. Castro O. Ognibene F.P. 2004 Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. New England Journal of Medicine, 350, 886 895.
-
(2004)
New England Journal of Medicine
, vol.350
, pp. 886-895
-
-
Gladwin, M.T.1
Sachdev, V.2
Jison, M.L.3
Shizukuda, Y.4
Plehn, J.F.5
Minter, K.6
Brown, B.7
Coles, W.A.8
Nichols, J.S.9
Ernst, I.10
Hunter, L.A.11
Blackwelder, W.C.12
Schechter, A.N.13
Rodgers, G.P.14
Castro, O.15
Ognibene, F.P.16
-
13
-
-
0032977037
-
Detection of nitrosyl hemoglobin in venous blood in the treatment of sickle cell anemia with hydroxyurea
-
Glover R.E. Ivy E.D. Orringer E.P. Maeda H. Mason R.P. 1999 Detection of nitrosyl hemoglobin in venous blood in the treatment of sickle cell anemia with hydroxyurea. Molecular Pharmacology, 55, 1006 1010.
-
(1999)
Molecular Pharmacology
, vol.55
, pp. 1006-1010
-
-
Glover, R.E.1
Ivy, E.D.2
Orringer, E.P.3
Maeda, H.4
Mason, R.P.5
-
14
-
-
0042805260
-
Hemolytic anemia-associated pulmonary hypertension of sickle cell disease and the nitric oxide/arginine pathway
-
Jison M.L. Gladwin M.T. 2003 Hemolytic anemia-associated pulmonary hypertension of sickle cell disease and the nitric oxide/arginine pathway. American Journal of Respiratory and Critical Care Medicine, 168, 3 4.
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.168
, pp. 3-4
-
-
Jison, M.L.1
Gladwin, M.T.2
-
15
-
-
20044379163
-
Acute on chronic pulmonary hypertension in patients with sickle cell disease
-
Kato G.J. Martyr S. Machado R. Sachdev V. Ernst I. Hunter L. Coles W. Nichols J. Hunter C.J. Gladwin M.T. 2004 Acute on chronic pulmonary hypertension in patients with sickle cell disease. Blood, 104, 1669a.
-
(2004)
Blood
, vol.104
-
-
Kato, G.J.1
Martyr, S.2
MacHado, R.3
Sachdev, V.4
Ernst, I.5
Hunter, L.6
Coles, W.7
Nichols, J.8
Hunter, C.J.9
Gladwin, M.T.10
-
16
-
-
27244435213
-
Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality
-
Kato G.J. Martyr S. Blackwelder W.C. Nichols J.S. Coles W.A. Hunter L.A. Brennan M.L. Hazen S.L. Gladwin M.T. 2005 Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality. British Journal of Haematology, 130, 943 953.
-
(2005)
British Journal of Haematology
, vol.130
, pp. 943-953
-
-
Kato, G.J.1
Martyr, S.2
Blackwelder, W.C.3
Nichols, J.S.4
Coles, W.A.5
Hunter, L.A.6
Brennan, M.L.7
Hazen, S.L.8
Gladwin, M.T.9
-
17
-
-
20044386727
-
Chronic sickle cell lung disease: New insights into the diagnosis, pathogenesis and treatment of pulmonary hypertension
-
Machado R.F. Gladwin M.T. 2005 Chronic sickle cell lung disease: new insights into the diagnosis, pathogenesis and treatment of pulmonary hypertension. British Journal of Haematology, 129, 449 464.
-
(2005)
British Journal of Haematology
, vol.129
, pp. 449-464
-
-
MacHado, R.F.1
Gladwin, M.T.2
-
18
-
-
33744827301
-
Natriuretic peptide levels correlate with pulmonary pressures and prospective mortality in SCD: Use of this biomarker to identify prevalence and mortality of pulmonary hypertension in the MSH cohort
-
Machado R. Steinberg M. Bonds D. Ballas S. Blackwelder W. Barton B. Waclawiw M. Castro O. Gladwin M.T. 2005 Natriuretic peptide levels correlate with pulmonary pressures and prospective mortality in SCD: use of this biomarker to identify prevalence and mortality of pulmonary hypertension in the MSH cohort. Blood, 106, 1a.
-
(2005)
Blood
, vol.106
-
-
MacHado, R.1
Steinberg, M.2
Bonds, D.3
Ballas, S.4
Blackwelder, W.5
Barton, B.6
Waclawiw, M.7
Castro, O.8
Gladwin, M.T.9
-
19
-
-
0142215534
-
Investigators of the cooperative study of sickle cell disease. Causes of death in sickle cell disease: An autopsy study
-
Manci E.A. Culberson D.E. Yang Y.M. Gardner T.M. Powell R. Haynes Jr., J. Shah A.K. Mankad V.N. 2003 Investigators of the cooperative study of sickle cell disease. Causes of death in sickle cell disease: an autopsy study. British Journal of Haematology, 123, 359 365.
-
(2003)
British Journal of Haematology
, vol.123
, pp. 359-365
-
-
Manci, E.A.1
Culberson, D.E.2
Yang, Y.M.3
Gardner, T.M.4
Powell, R.5
Haynesjr, J.6
Shah, A.K.7
Mankad, V.N.8
-
20
-
-
23244449046
-
B-type natriuretic peptide as a biomarker beyond heart failure: Speculations and opportunities
-
McKie P.M. Burnett Jr., J.C. 2005 B-type natriuretic peptide as a biomarker beyond heart failure: speculations and opportunities. Mayo Clinic Proceedings, 80, 1029 1036.
-
(2005)
Mayo Clinic Proceedings
, vol.80
, pp. 1029-1036
-
-
McKie, P.M.1
Burnettjr, C.J.2
-
21
-
-
0035808004
-
Clinical correlates and reference intervals for pulmonary artery systolic pressure among echocardiographically normal subjects
-
McQuillan B.M. Picard M.H. Leavitt M. Weyman A.E. 2001 Clinical correlates and reference intervals for pulmonary artery systolic pressure among echocardiographically normal subjects. Circulation, 104, 2797 2802.
-
(2001)
Circulation
, vol.104
, pp. 2797-2802
-
-
McQuillan, B.M.1
Picard, M.H.2
Leavitt, M.3
Weyman, A.E.4
-
22
-
-
0043204998
-
Arginine therapy: A new treatment for pulmonary hypertension in sickle cell disease
-
Morris C.R. Morris S.M. Hagar W. Van Warmerdam J. Claster S. Kepka-Lenhart D. Machado L. Kuypers F.A. Vichinsky E.P. 2003 Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease American Journal of Respiratory and Critical Care Medicine, 168, 63 69.
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.168
, pp. 63-69
-
-
Morris, C.R.1
Morris, S.M.2
Hagar, W.3
Van Warmerdam, J.4
Claster, S.5
Kepka-Lenhart, D.6
MacHado, L.7
Kuypers, F.A.8
Vichinsky, E.P.9
-
23
-
-
21444441271
-
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease
-
Morris C.R. Kato G.J. Poljakovic M. Wang X. Blackwelder W.C. Sachdev V. Hazen S.L. Vichinsky E.P. Morris Jr., S.M. Gladwin M.T. 2005 Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. Journal of the American Medical Association, 294, 81 90.
-
(2005)
Journal of the American Medical Association
, vol.294
, pp. 81-90
-
-
Morris, C.R.1
Kato, G.J.2
Poljakovic, M.3
Wang, X.4
Blackwelder, W.C.5
Sachdev, V.6
Hazen, S.L.7
Vichinsky, E.P.8
Morrisjr, M.S.9
Gladwin, M.T.10
-
25
-
-
0025770390
-
Pain in sickle cell disease. Rates and risk factors
-
Platt O.S. Thorington B.D. Brambilla D.J. Milner P.F. Rosse W.F. Vichinsky E. Kinney T.R. 1991 Pain in sickle cell disease. Rates and risk factors. New England Journal of Medicine, 325, 11 16.
-
(1991)
New England Journal of Medicine
, vol.325
, pp. 11-16
-
-
Platt, O.S.1
Thorington, B.D.2
Brambilla, D.J.3
Milner, P.F.4
Rosse, W.F.5
Vichinsky, E.6
Kinney, T.R.7
-
26
-
-
0028291736
-
Mortality in sickle cell disease: Life expectancy and risk factors for early death
-
Platt O.S. Brambilla D.J. Rosse W.F. Milner P.F. Castro O. Steinberg M.H. Klug P.P. 1994 Mortality in sickle cell disease: life expectancy and risk factors for early death. New England Journal of Medicine, 330, 1639 1644.
-
(1994)
New England Journal of Medicine
, vol.330
, pp. 1639-1644
-
-
Platt, O.S.1
Brambilla, D.J.2
Rosse, W.F.3
Milner, P.F.4
Castro, O.5
Steinberg, M.H.6
Klug, P.P.7
-
27
-
-
0036908599
-
Cell-free hemoglobin limits nitric oxide bioavailability in sickle cell disease
-
Reiter C.D. Wang X. Tanus-Santos J.E. Hogg N. Cannon R.O., III. Schechter A.N. Gladwin M.T. 2002 Cell-free hemoglobin limits nitric oxide bioavailability in sickle cell disease. Nature Medicine, 8, 1383 1389.
-
(2002)
Nature Medicine
, vol.8
, pp. 1383-1389
-
-
Reiter, C.D.1
Wang, X.2
Tanus-Santos, J.E.3
Hogg, N.4
Cannon, R.O.5
Iii6
Schechter, A.N.7
Gladwin, M.T.8
-
28
-
-
0032873984
-
Levels of endothelial, neutrophil and platelet-specific factors in sickle cell anemia patients during hydroxyurea therapy
-
Saleh A.W. Hillen H.F. Duits A.J. 1999 Levels of endothelial, neutrophil and platelet-specific factors in sickle cell anemia patients during hydroxyurea therapy. Acta Haematologica, 102, 31 37.
-
(1999)
Acta Haematologica
, vol.102
, pp. 31-37
-
-
Saleh, A.W.1
Hillen, H.F.2
Duits, A.J.3
-
29
-
-
0023772122
-
Two-dimensional echo and Doppler ultrasonographic findings in the hearts of adults with sickle cell anemia
-
Simons B.E. Santhanam V. Castaner A.J. Rao K.R. Sachdev N. Cooper R. 1988 Two-dimensional echo and Doppler ultrasonographic findings in the hearts of adults with sickle cell anemia. Archives of Internal Medicine, 148, 1526 1528.
-
(1988)
Archives of Internal Medicine
, vol.148
, pp. 1526-1528
-
-
Simons, B.E.1
Santhanam, V.2
Castaner, A.J.3
Rao, K.R.4
Sachdev, N.5
Cooper, R.6
-
30
-
-
0018565753
-
Gelation of sickle cell hemoglobin in mixtures with normal adult and fetal hemoglobins
-
Sunshine H.R. Hofrichter J. Eaton W.A. 1979 Gelation of sickle cell hemoglobin in mixtures with normal adult and fetal hemoglobins. Journal of Molecular Biology, 133, 435 467.
-
(1979)
Journal of Molecular Biology
, vol.133
, pp. 435-467
-
-
Sunshine, H.R.1
Hofrichter, J.2
Eaton, W.A.3
-
32
-
-
0031745980
-
Successful pulmonary thromboendarterectomy in two patients with sickle cell disease
-
Yung G.L. Channick R.N. Fedullo P.F. Auger W.R. Kerr K.M. Jamieson S.W. Kapelanski D.P. Moser K.M. 1998 Successful pulmonary thromboendarterectomy in two patients with sickle cell disease. American Journal of Respiratory and Critical Care Medicine, 157, 1690 1693.
-
(1998)
American Journal of Respiratory and Critical Care Medicine
, vol.157
, pp. 1690-1693
-
-
Yung, G.L.1
Channick, R.N.2
Fedullo, P.F.3
Auger, W.R.4
Kerr, K.M.5
Jamieson, S.W.6
Kapelanski, D.P.7
Moser, K.M.8
|