MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma

Oncotarget

Volumn 6, Issue 6, 2015, Pages 3770-3783

  Teplyuk, Nadiya M ^a   Uhlmann, Erik J ^a   Wong, Andus Hon Kit ^a   Karmali, Priya ^b   Basu, Meenakshi ^a   Gabriely, Galina ^a   Jain, Anant ^a   Wang, Yang ^a   Antonio Chiocca, E ^c   Stephens, Robert ^d   Marcusson, Eric ^b   Yi, Ming ^d   Krichevsky, Anna M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b REGULUS THERAPEUTICS   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

Author keywords

Cell cycle; E2F1 transcription; Glioblastoma; miR 10b; P21

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN E; MICRORNA; MICRORNA 10B; MICRORNA 15; MICRORNA 16; PROTEIN P21; TRANSCRIPTION FACTOR E2F1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; E2F1 PROTEIN, HUMAN; MIRN10 MICRORNA, HUMAN; MIRN15 MICRORNA, HUMAN; MIRN16 MICRORNA, HUMAN;

ARTICLE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CONTROLLED STUDY; DOWN REGULATION; ENZYME REPRESSION; EPIGENETICS; G2 PHASE CELL CYCLE CHECKPOINT; GENE ACTIVITY; GENE CLUSTER; GENE CONTROL; GENE TARGETING; GENETIC CODE; GENETIC TRANSCRIPTION; GLIOBLASTOMA; GLIOMA CELL LINE; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANTAGONISTS AND INHIBITORS; BRAIN TUMOR; CELL GROWTH; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

BRAIN NEOPLASMS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; MICRORNAS; TRANSCRIPTION, GENETIC;

EID: 84924244262     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3009     Document Type: Article

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