-
1
-
-
0025068887
-
Suppression of tumourigenicity of human prostate carcinoma cells by replacing a mutated Rb gene
-
Brookstein R, Shew JY, Chen PL, Scully P, Lee WH (1990) Suppression of tumourigenicity of human prostate carcinoma cells by replacing a mutated Rb gene. Science 247:712-715
-
(1990)
Science
, vol.247
, pp. 712-715
-
-
Brookstein, R.1
Shew, J.Y.2
Chen, P.L.3
Scully, P.4
Lee, W.H.5
-
2
-
-
0025905183
-
The E2F transcription factor is a cellular target for the Rb protein
-
Chellapan SP, Hiebert S, Mudryj M, Horowitz JM, Nevin JR (1991) The E2F transcription factor is a cellular target for the Rb protein. Cell 65:1053-1061
-
(1991)
Cell
, vol.65
, pp. 1053-1061
-
-
Chellapan, S.P.1
Hiebert, S.2
Mudryj, M.3
Horowitz, J.M.4
Nevin, J.R.5
-
3
-
-
0028899480
-
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
-
Chen J, Jackson PK, Kirschner MW, Dutta (1995) Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature 374:386-388
-
(1995)
Nature
, vol.374
, pp. 386-388
-
-
Chen, J.1
Jackson, P.K.2
Kirschner, M.W.3
Dutta4
-
4
-
-
0027944070
-
Prognostic implications of p53 overexpression in supratentorial astrocytic tumors
-
Chozick BS, Pezzullo JC, Epstein MH, Finch PW (1994) Prognostic implications of p53 overexpression in supratentorial astrocytic tumors. Neurosurgery 35:831-838
-
(1994)
Neurosurgery
, vol.35
, pp. 831-838
-
-
Chozick, B.S.1
Pezzullo, J.C.2
Epstein, M.H.3
Finch, P.W.4
-
5
-
-
0027367487
-
Regional heterogeneity in the proliferative activity of human gliomas as measured by the Ki-67 labeling index
-
Coons SW, Johnson PC (1993) Regional heterogeneity in the proliferative activity of human gliomas as measured by the Ki-67 labeling index. J Neuropathol Exp Neurol 52:609-618
-
(1993)
J Neuropathol Exp Neurol
, vol.52
, pp. 609-618
-
-
Coons, S.W.1
Johnson, P.C.2
-
6
-
-
0000336139
-
Regression models and life tables
-
Cox DR (1972) Regression models and life tables. J Roy Stat B 34:187-220
-
(1972)
J Roy Stat B
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
7
-
-
0031033359
-
Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: Relationships and prognostic value
-
Cunningham J, Kimmel DW, Scheithauer BW, O'Fallon JR, Novotny PJ, Jenkins RB (1997) Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: relationships and prognostic value. J Neurosurg 86:121-130
-
(1997)
J Neurosurg
, vol.86
, pp. 121-130
-
-
Cunningham, J.1
Kimmel, D.W.2
Scheithauer, B.W.3
O'Fallon, J.R.4
Novotny, P.J.5
Jenkins, R.B.6
-
8
-
-
0026629404
-
p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma
-
Deimling A von, Eibl RH, Ohgaki H, Louis DN, Ammon K von, Petersen I, Kleihues P, Chung RY, Wiestler OD, Seizinger BR (1992) p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. Cancer Res 52:2987-2990
-
(1992)
Cancer Res
, vol.52
, pp. 2987-2990
-
-
Von Deimling, A.1
Eibl, R.H.2
Ohgaki, H.3
Louis, D.N.4
Von Ammon, K.5
Petersen, I.6
Kleihues, P.7
Chung, R.Y.8
Wiestler, O.D.9
Seizinger, B.R.10
-
9
-
-
0028970946
-
p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma
-
DiGiuseppe JA, Redstone MS, Yeo CJ, Kern SE, Hrulan RH (1995) p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma. Am J Pathol 147: 884-888
-
(1995)
Am J Pathol
, vol.147
, pp. 884-888
-
-
DiGiuseppe, J.A.1
Redstone, M.S.2
Yeo, C.J.3
Kern, S.E.4
Hrulan, R.H.5
-
10
-
-
0027359827
-
WAF1, a potent mediator of p53 tumor suppression
-
El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993) WAF1, a potent mediator of p53 tumor suppression. Cell 75: 817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
11
-
-
0028124690
-
Aberrant RB gene expression in routinely processed, archival tumor tissues determined by three different anti-RB antibodies
-
Geradts J, Hu S-X, Lincoln CE, Benedict WF, Xu H-J (1994) Aberrant RB gene expression in routinely processed, archival tumor tissues determined by three different anti-RB antibodies. Int J Caner 58:161-167
-
(1994)
Int J Caner
, vol.58
, pp. 161-167
-
-
Geradts, J.1
Hu, S.-X.2
Lincoln, C.E.3
Benedict, W.F.4
Xu, H.-J.5
-
12
-
-
0026058874
-
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
-
Goodrich DW, Wang WP, Qian Y-W, Lee E Y-P, Lee WH (1991) The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell 67:293-302
-
(1991)
Cell
, vol.67
, pp. 293-302
-
-
Goodrich, D.W.1
Wang, W.P.2
Qian, Y.-W.3
Lee, E.Y.-P.4
Lee, W.H.5
-
13
-
-
0029119740
-
Cell cycle control in mammalian cells: Role of cyclins, cyclin-dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)
-
Granna X, Reddy EP (1995) Cell cycle control in mammalian cells: role of cyclins, cyclin-dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 11:211-219
-
(1995)
Oncogene
, vol.11
, pp. 211-219
-
-
Granna, X.1
Reddy, E.P.2
-
14
-
-
0023686773
-
Abonormalities in structure and expression of the human retinoblastoma gene in SCLC
-
Harbour JW, Li S-L, Whang-Peng J, Gazdar AF, Minna JD, Kaye FJ (1988) Abonormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 241:353-357
-
(1988)
Science
, vol.241
, pp. 353-357
-
-
Harbour, J.W.1
Li, S.-L.2
Whang-Peng, J.3
Gazdar, A.F.4
Minna, J.D.5
Kaye, F.J.6
-
15
-
-
0027496935
-
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper JW, Adami GR, Wei N, Keyomarsi E, Elledge SJ (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, E.4
Elledge, S.J.5
-
16
-
-
0028970955
-
Lack of p16 (INK4) or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distrinct subsets of malignant glial cell tumors and cell lines
-
He J, Olson JJ, James CD (1995) Lack of p16 (INK4) or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distrinct subsets of malignant glial cell tumors and cell lines. Cancer Res 55:4833-4836
-
(1995)
Cancer Res
, vol.55
, pp. 4833-4836
-
-
He, J.1
Olson, J.J.2
James, C.D.3
-
17
-
-
0027943938
-
The retinoblastoma susceptibility (Rb) gene is involved in the malignant progression of human astrocytomas
-
Henson JW, Schnitker BL, Correa KM, Deimling A von, Fassbender F, Xu H-J, Benedict WF, Yandell DW, Louis DN (1994) The retinoblastoma susceptibility (Rb) gene is involved in the malignant progression of human astrocytomas. Ann Neurol 36: 714-721
-
(1994)
Ann Neurol
, vol.36
, pp. 714-721
-
-
Henson, J.W.1
Schnitker, B.L.2
Correa, K.M.3
Von Deimling, A.4
Fassbender, F.5
Xu, H.-J.6
Benedict, W.F.7
Yandell, D.W.8
Louis, D.N.9
-
18
-
-
0024500043
-
Point mutational inactivation of the retinoblastoma antioncogene
-
Horowitz JM, Yandell DW, Park S-H, Canning S, Whyte P, Buchkovich KJ, Harlew E, Weinberg RA, Dryja TP (1989) Point mutational inactivation of the retinoblastoma antioncogene. Science 243:937-940
-
(1989)
Science
, vol.243
, pp. 937-940
-
-
Horowitz, J.M.1
Yandell, D.W.2
Park, S.-H.3
Canning, S.4
Whyte, P.5
Buchkovich, K.J.6
Harlew, E.7
Weinberg, R.A.8
Dryja, T.P.9
-
19
-
-
0025304297
-
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells
-
Horowitz JM, Park S-H, Bogenmann E, Cheng J-C, Yandell DM, Kaye FJ, Minna JD, Dryja TP, Weinberg RA (1990) Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc Natl Acad Sci USA 87:2775-2779
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 2775-2779
-
-
Horowitz, J.M.1
Park, S.-H.2
Bogenmann, E.3
Cheng, J.-C.4
Yandell, D.M.5
Kaye, F.J.6
Minna, J.D.7
Dryja, T.P.8
Weinberg, R.A.9
-
20
-
-
0028973586
-
Increased levels of p21 (WAF1/Cip1) in human brain tumors
-
Jung J-M, Bruner JM, Ruan S, Langford LA, Kyritsis AP, Kobayashi T, Levin VA, Zhang W (1995) Increased levels of p21 (WAF1/Cip1) in human brain tumors. Oncogene 11:2021-2028
-
(1995)
Oncogene
, vol.11
, pp. 2021-2028
-
-
Jung, J.-M.1
Bruner, J.M.2
Ruan, S.3
Langford, L.A.4
Kyritsis, A.P.5
Kobayashi, T.6
Levin, V.A.7
Zhang, W.8
-
22
-
-
0028852067
-
Multiple polymorphisms, but no mutations, in the WAF1/CIP1 gene in human brain tumours
-
Koopmann J, Maintz D, Schild S, Schramm J, Louis DN, Wiestler OD, Deimling A von (1995) Multiple polymorphisms, but no mutations, in the WAF1/CIP1 gene in human brain tumours. Br J Cancer 72:1230-1233
-
(1995)
Br J Cancer
, vol.72
, pp. 1230-1233
-
-
Koopmann, J.1
Maintz, D.2
Schild, S.3
Schramm, J.4
Louis, D.N.5
Wiestler, O.D.6
Von Deimling, A.7
-
23
-
-
0024281617
-
Inactivation of the retinoblastoma susceptibility gene in human breast cancers
-
Lee EY-HP, To H, Shew J-Y, Brookstein R, Scully P, Lee W-H (1988) Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science 241:218-221
-
(1988)
Science
, vol.241
, pp. 218-221
-
-
Lee, E.Y.-H.P.1
To, H.2
Shew, J.-Y.3
Brookstein, R.4
Scully, P.5
Lee, W.-H.6
-
24
-
-
0026034418
-
Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase
-
Lin BT-Y, Gruenwold S, Morla AO, Lee WH, Wang JY (1991) Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase. EMBO J 10:857-864
-
(1991)
EMBO J
, vol.10
, pp. 857-864
-
-
Lin, B.T.-Y.1
Gruenwold, S.2
Morla, A.O.3
Lee, W.H.4
Wang, J.Y.5
-
25
-
-
0029063745
-
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21 Cip1
-
Luo Y, Hurwitz J, Massagué J (1995) Cell-cycle inhibition by independent CDK and PCNA binding domains in p21 Cip1. Nature 375:159-161
-
(1995)
Nature
, vol.375
, pp. 159-161
-
-
Luo, Y.1
Hurwitz, J.2
Massagué, J.3
-
26
-
-
0028967318
-
p53, Rb and bcl2 expression during the cell cycle: A study in phytohaemagglutinin stimulated lymphocytes and microware irradiated lymphoid tissue sections
-
Mateo MS, Sanchez-Beato M, Martinez JC, Orfao A, Orradre JL, Piris MA (1995) p53, Rb and bcl2 expression during the cell cycle: a study in phytohaemagglutinin stimulated lymphocytes and microware irradiated lymphoid tissue sections. J Clin Pathol 48:151-159
-
(1995)
J Clin Pathol
, vol.48
, pp. 151-159
-
-
Mateo, M.S.1
Sanchez-Beato, M.2
Martinez, J.C.3
Orfao, A.4
Orradre, J.L.5
Piris, M.A.6
-
27
-
-
0029916697
-
Immunohistochemical detection of CDKN2, retinoblastoma and p53 gene products in primary astrocytic tumors
-
Nakamura M, Konishi N, Hiasa Y, Tsunoda S, Fukushima Y, Tsuzuki T, Takemura K, Aoki H, Kobitsu K, Sakaki T (1996) Immunohistochemical detection of CDKN2, retinoblastoma and p53 gene products in primary astrocytic tumors. Int J Oncol 8:889-893
-
(1996)
Int J Oncol
, vol.8
, pp. 889-893
-
-
Nakamura, M.1
Konishi, N.2
Hiasa, Y.3
Tsunoda, S.4
Fukushima, Y.5
Tsuzuki, T.6
Takemura, K.7
Aoki, H.8
Kobitsu, K.9
Sakaki, T.10
-
28
-
-
0027980256
-
Brief, high-temperature heat denaturation (pressure cooking): A simple and effective method of antigen retrieval for routinely processed tissues
-
Norton AJ, Jordan S, Yeomans P (1994) Brief, high-temperature heat denaturation (pressure cooking): a simple and effective method of antigen retrieval for routinely processed tissues. J Pathol 173:371-379
-
(1994)
J Pathol
, vol.173
, pp. 371-379
-
-
Norton, A.J.1
Jordan, S.2
Yeomans, P.3
-
29
-
-
0029823960
-
Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices
-
Ono Y, Tamiya T, Ichikawa I, Kunishio K, Matsumoto K, Furuta T, Ohmoto T, Ueki K, Louis DN (1996) Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices. J Neuropathol Exp Neurol 55:1026-1031
-
(1996)
J Neuropathol Exp Neurol
, vol.55
, pp. 1026-1031
-
-
Ono, Y.1
Tamiya, T.2
Ichikawa, I.3
Kunishio, K.4
Matsumoto, K.5
Furuta, T.6
Ohmoto, T.7
Ueki, K.8
Louis, D.N.9
-
30
-
-
0030877997
-
Accumulation of wild-type p53 in astrocytomas is associated with increased p21 expression
-
Ono Y, Tamiya T, Ichikawa I, Matsumoto K, Furuta T, Ohmoto T, Akiyama K, Seki S, Ueki K, Louis DN (1997) Accumulation of wild-type p53 in astrocytomas is associated with increased p21 expression. Acta Neuropathol 94:21-27
-
(1997)
Acta Neuropathol
, vol.94
, pp. 21-27
-
-
Ono, Y.1
Tamiya, T.2
Ichikawa, I.3
Matsumoto, K.4
Furuta, T.5
Ohmoto, T.6
Akiyama, K.7
Seki, S.8
Ueki, K.9
Louis, D.N.10
-
32
-
-
0029743494
-
Anomalous retinoblastoma protein expression in Sternberg-Reed cells in Hodgkin's disease: A comparative study with p53 and Ki-67 expression
-
Sanchez-Beato M, Martinez-Montero JC, Doussis-Anagnostopoulou TA, Gatter KC, Garcia J, Garcia JF, LLoret E, Piris MA (1996) Anomalous retinoblastoma protein expression in Sternberg-Reed cells in Hodgkin's disease: a comparative study with p53 and Ki-67 expression. Br J Cancer 74:1056-1062
-
(1996)
Br J Cancer
, vol.74
, pp. 1056-1062
-
-
Sanchez-Beato, M.1
Martinez-Montero, J.C.2
Doussis-Anagnostopoulou, T.A.3
Gatter, K.C.4
Garcia, J.5
Garcia, J.F.6
Lloret, E.7
Piris, M.A.8
-
33
-
-
0027940495
-
Absence of WAF1 mutations in a variety of human malignancies
-
Shiohara M, El-Deiry WS, Wada M, Nakamaki T, Takenchi S, Yang R, Chen D-L, Vogelstein B, Koeffler PH (1994) Absence of WAF1 mutations in a variety of human malignancies. Blood 84:3781-3784
-
(1994)
Blood
, vol.84
, pp. 3781-3784
-
-
Shiohara, M.1
El-Deiry, W.S.2
Wada, M.3
Nakamaki, T.4
Takenchi, S.5
Yang, R.6
Chen, D.-L.7
Vogelstein, B.8
Koeffler, P.H.9
-
34
-
-
0028555778
-
p53 immunohistochemical positivity as a prognostic marker in intracranial tumours
-
Soini Y, Niemela A, Kamel D, Herva R, Bloigu R, Paako P, Vahakangas K (1994) p53 immunohistochemical positivity as a prognostic marker in intracranial tumours. APMIS 102:786-792
-
(1994)
APMIS
, vol.102
, pp. 786-792
-
-
Soini, Y.1
Niemela, A.2
Kamel, D.3
Herva, R.4
Bloigu, R.5
Paako, P.6
Vahakangas, K.7
-
35
-
-
0030056824
-
Alterations of retinoblastoma, p53, p16 (CDKN2) and p15 genes in human astrocytomas
-
Tsuzuki T, Tsunoda S, Sakaki T, Konishi N, Hiasa Y, Nakamura M (1996) Alterations of retinoblastoma, p53, p16 (CDKN2) and p15 genes in human astrocytomas. Cancer 78:287-293
-
(1996)
Cancer
, vol.78
, pp. 287-293
-
-
Tsuzuki, T.1
Tsunoda, S.2
Sakaki, T.3
Konishi, N.4
Hiasa, Y.5
Nakamura, M.6
-
36
-
-
0030070484
-
CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated
-
Ueki K, Ono Y, Henson JW, Efird JT, Deimling A von, Louis DN (1996) CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res 56: 150-153
-
(1996)
Cancer Res
, vol.56
, pp. 150-153
-
-
Ueki, K.1
Ono, Y.2
Henson, J.W.3
Efird, J.T.4
Von Deimling, A.5
Louis, D.N.6
-
37
-
-
0026033511
-
Retinoblastoma gene deletions in human glioblastomas
-
Venter DJ, Bevan KL, Ludwig RL, Riley TL, Jat PS, Thomas DG, Noble MD (1991) Retinoblastoma gene deletions in human glioblastomas. Oncogene 6:445-448
-
(1991)
Oncogene
, vol.6
, pp. 445-448
-
-
Venter, D.J.1
Bevan, K.L.2
Ludwig, R.L.3
Riley, T.L.4
Jat, P.S.5
Thomas, D.G.6
Noble, M.D.7
-
38
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kineases
-
Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D (1993) p21 is a universal inhibitor of cyclin kineases. Nature 366:701-704
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
39
-
-
0025883860
-
Lack of nuclear RB protein staining in G0/middle G1 cells: Correlation to changes in total RB protein level
-
Xu H-J, Xu S-X, Benedict WF (1991) Lack of nuclear RB protein staining in G0/middle G1 cells: correlation to changes in total RB protein level. Oncogene 6:1139-1144
-
(1991)
Oncogene
, vol.6
, pp. 1139-1144
-
-
Xu, H.-J.1
Xu, S.-X.2
Benedict, W.F.3
-
40
-
-
0028169236
-
p21-containing cyclin kinases exist in both active and inactive states
-
Zhang H, Hannon GJ, Beach D (1994) p21-containing cyclin kinases exist in both active and inactive states. Genes Dev 8: 1750-1758
-
(1994)
Genes Dev
, vol.8
, pp. 1750-1758
-
-
Zhang, H.1
Hannon, G.J.2
Beach, D.3
-
41
-
-
0028985518
-
p53 independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation
-
Zhang W, Grasso L, McClain CD, Gambel AM, Cha Y, Travoli S, Deisseroth AB, Mercer WE (1995) p53 independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation. Cancer Res 55:668-674
-
(1995)
Cancer Res
, vol.55
, pp. 668-674
-
-
Zhang, W.1
Grasso, L.2
McClain, C.D.3
Gambel, A.M.4
Cha, Y.5
Travoli, S.6
Deisseroth, A.B.7
Mercer, W.E.8
-
42
-
-
0029102010
-
High levels of constitutive WAF1/Cip1 protein are associated with chemoresistance in clinical acute myelogenous leukemia
-
Zhang W, Kornblau SM, Kobayashi T, Gambel A, Claxton D, Deisseroth AB (1995) High levels of constitutive WAF1/Cip1 protein are associated with chemoresistance in clinical acute myelogenous leukemia. Cancer Res 1:1051-1057
-
(1995)
Cancer Res
, vol.1
, pp. 1051-1057
-
-
Zhang, W.1
Kornblau, S.M.2
Kobayashi, T.3
Gambel, A.4
Claxton, D.5
Deisseroth, A.B.6
|