-
2
-
-
70449705831
-
The spectrum of latent tuberculosis: Rethinking the biology and intervention strategies
-
C. E. Barry, H. I. Boshoff, V. Dartois, T. Dick, S. Ehrt, J. Flynn, D. Schnappinger, R. J. Wilkinson and D. Young, The spectrum of latent tuberculosis: Rethinking the biology and intervention strategies, Nature reviews. Microbiology, 7 (2009), 845-855.
-
(2009)
Nature Reviews. Microbiology
, vol.7
, pp. 845-855
-
-
Barry, C.E.1
Boshoff, H.I.2
Dartois, V.3
Dick, T.4
Ehrt, S.5
Flynn, J.6
Schnappinger, D.7
Wilkinson, R.J.8
Young, D.9
-
3
-
-
0029114828
-
The intrinsic transmission dynamics of tuberculosis epidemics
-
S. M. Blower, A. R. McLean, T. C. Porco, P. M. Small, P. C. Hopewell, M. A. Sanchez and A. R. Moss, The intrinsic transmission dynamics of tuberculosis epidemics, Nature Medicine, 1 (1995), 815-821.
-
(1995)
Nature Medicine
, vol.1
, pp. 815-821
-
-
Blower, S.M.1
McLean, A.R.2
Porco, T.C.3
Small, P.M.4
Hopewell, P.C.5
Sanchez, M.A.6
Moss, A.R.7
-
4
-
-
33947711645
-
New insights on the nature of latent tuberculosis infection and its treatment
-
P.-J. Cardona, New insights on the nature of latent tuberculosis infection and its treatment, Inflammation & allergy drug targets, 6 (2007), 27-39.
-
(2007)
Inflammation & Allergy Drug Targets
, vol.6
, pp. 27-39
-
-
Cardona, P.-J.1
-
7
-
-
0036078710
-
Dissemination of mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity
-
A. A. Chackerian, J. M. Alt, T. V. Perera, C. C. Dascher and S. M. Behar, Dissemination of Mycobacterium tuberculosis Is Influenced by Host Factors and Precedes the Initiation of T-Cell Immunity, Infection and Immunity, 70 (2002), 4501-4509.
-
(2002)
Infection and Immunity
, vol.70
, pp. 4501-4509
-
-
Chackerian, A.A.1
Alt, J.M.2
Perera, T.V.3
Dascher, C.C.4
Behar, S.M.5
-
8
-
-
84880273351
-
Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during mycobacterium tuberculosis infection
-
N. A. Cilfone, C. R. Perry, D. E. Kirschner and J. J. Linderman, Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection, PloS one, 8 (2013), e68680.
-
(2013)
PloS One
, vol.8
-
-
Cilfone, N.A.1
Perry, C.R.2
Kirschner, D.E.3
Linderman, J.J.4
-
9
-
-
84915818775
-
PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis
-
M. T. Coleman, R. Y. Chen, M. Lee, P. L. Lin, L. E. Dodd, P. Maiello, L. E. Via, Y. Kim, G. Marriner, V. Dartois, C. Scanga, C. Janssen, J. Wang, E. Klein, S. N. Cho, C. E. Barry 3rd and J. L. Flynn, PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis, Sci Transl Med, 6 (2014), p265ra167.
-
(2014)
Sci Transl Med
, vol.6
-
-
Coleman, M.T.1
Chen, R.Y.2
Lee, M.3
Lin, P.L.4
Dodd, L.E.5
Maiello, P.6
Via, L.E.7
Kim, Y.8
Marriner, G.9
Dartois, V.10
Scanga, C.11
Janssen, C.12
Wang, J.13
Klein, E.14
Cho, S.N.15
Barry, C.E.16
Flynn, J.L.17
-
10
-
-
0022648221
-
Drug-induced pulmonary disease. Part 1: Cytotoxic drugs
-
J. A. Cooper, D. A. White and R. A. Matthay, Drug-induced pulmonary disease. Part 1: Cytotoxic drugs, The American review of respiratory disease, 133 (1986), 321-340.
-
(1986)
The American Review of Respiratory Disease
, vol.133
, pp. 321-340
-
-
Cooper, J.A.1
White, D.A.2
Matthay, R.A.3
-
11
-
-
0012746992
-
The growing burden of tuberculosis: Global trends and interactions with the HIV epidemic
-
E. L. Corbett, C. J. Watt, N. Walker, D. Maher, B. G. Williams, M. C. Raviglione and C. Dye, The growing burden of tuberculosis: Global trends and interactions with the HIV epidemic, Archives of internal medicine, 163 (2003), 1009-1021.
-
(2003)
Archives of Internal Medicine
, vol.163
, pp. 1009-1021
-
-
Corbett, E.L.1
Watt, C.J.2
Walker, N.3
Maher, D.4
Williams, B.G.5
Raviglione, M.C.6
Dye, C.7
-
13
-
-
77953160649
-
The construction of next-generation matrices for compartmental epidemic models
-
O. Diekmann, J. A. P. Heesterbeek and M. G. Roberts, The construction of next-generation matrices for compartmental epidemic models, Journal of the Royal Society, Interface / the Royal Society, 7 (2010), 873-885.
-
(2010)
Journal of the Royal Society, Interface / the Royal Society
, vol.7
, pp. 873-885
-
-
Diekmann, O.1
Heesterbeek, J.A.P.2
Roberts, M.G.3
-
14
-
-
0032512283
-
Prospects for worldwide tuberculosis control under the WHO DOTS strategy
-
C. Dye, G. P. Garnett, K. Sleeman and B. G. Williams, Prospects for worldwide tuberculosis control under the WHO DOTS strategy, The Lancet, 352 (1998), 1886-1891.
-
(1998)
The Lancet
, vol.352
, pp. 1886-1891
-
-
Dye, C.1
Garnett, G.P.2
Sleeman, K.3
Williams, B.G.4
-
15
-
-
84859377308
-
Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability
-
M. Fallahi-Sichani, J. L. Flynn, J. J. Linderman and D. E. Kirschner, Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability, Journal of immunology (Baltimore, Md.: 1950), 188 (2012), 3169-3178.
-
(2012)
Journal of Immunology (Baltimore, Md.: 1950)
, vol.188
, pp. 3169-3178
-
-
Fallahi-Sichani, M.1
Flynn, J.L.2
Linderman, J.J.3
Kirschner, D.E.4
-
17
-
-
77955478490
-
Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma
-
M. Fallahi-Sichani, M. A. Schaller, D. E. Kirschner, S. L. Kunkel and J. J. Linderman, Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma, PLoS computational biology, 6 (2010), e1000778, 19pp.
-
(2010)
PLoS Computational Biology
, vol.6
-
-
Fallahi-Sichani, M.1
Schaller, M.A.2
Kirschner, D.E.3
Kunkel, S.L.4
Linderman, J.J.5
-
18
-
-
0034040084
-
A model for tuberculosis with exogenous reinfection
-
Z. Feng, C. Castillo-Chavez and A. F. Capurro, A model for tuberculosis with exogenous reinfection, Theoretical population biology, 57 (2000), 235-247.
-
(2000)
Theoretical Population Biology
, vol.57
, pp. 235-247
-
-
Feng, Z.1
Castillo-Chavez, C.2
Capurro, A.F.3
-
20
-
-
84880946832
-
Predicting lymph node output efficiency using systems biology
-
C. Gong, J. T. Mattila, M. Miller, J. L. Flynn, J. J. Linderman and D. Kirschner, Predicting lymph node output efficiency using systems biology, Journal of theoretical biology, 335 (2013), 169-184.
-
(2013)
Journal of Theoretical Biology
, vol.335
, pp. 169-184
-
-
Gong, C.1
Mattila, J.T.2
Miller, M.3
Flynn, J.L.4
Linderman, J.J.5
Kirschner, D.6
-
21
-
-
80052824125
-
Modeling sociodemography to capture tuberculosis transmission dynamics in a low burden setting
-
G. Guzzetta, M. Ajelli, Z. Yang, S. Merler, C. Furlanello and D. Kirschner, Modeling sociodemography to capture tuberculosis transmission dynamics in a low burden setting, Journal of theoretical biology, 289 (2011), 197-205.
-
(2011)
Journal of Theoretical Biology
, vol.289
, pp. 197-205
-
-
Guzzetta, G.1
Ajelli, M.2
Yang, Z.3
Merler, S.4
Furlanello, C.5
Kirschner, D.6
-
22
-
-
0033080472
-
Dynamics of co-infection with M. Tuberculosis and HIV-1
-
D. Kirschner, Dynamics of co-infection with M. Tuberculosis and HIV-1, Theoretical population biology, 55 (1999), 94-109.
-
(1999)
Theoretical Population Biology
, vol.55
, pp. 94-109
-
-
Kirschner, D.1
-
23
-
-
33947236071
-
Toward a multiscale model of antigen presentation in immunity
-
D. E. Kirschner, S. T. Chang, T. W. Riggs, N. Perry and J. J. Linderman, Toward a multiscale model of antigen presentation in immunity, Immunological reviews, 216 (2007), 93-118.
-
(2007)
Immunological Reviews
, vol.216
, pp. 93-118
-
-
Kirschner, D.E.1
Chang, S.T.2
Riggs, T.W.3
Perry, N.4
Linderman, J.J.5
-
24
-
-
84882427707
-
Radiologic responses in cynomolgous macaques for assessing tuberculosis chemotherapy regimens
-
P. L. Lin, T. Coleman, J. P. J. Carney, B. J. Lopresti, J. Tomko, D. Fillmore, V. Dartois, C. Scanga, L. J. Frye, Ch. Janssen, E. Klein, C. E. Barry and Joanne L Flynn, Radiologic responses in cynomolgous macaques for assessing tuberculosis chemotherapy regimens, Antimicrobial agents and chemotherapy, 57 (2013), 4237-4244.
-
(2013)
Antimicrobial Agents and Chemotherapy
, vol.57
, pp. 4237-4244
-
-
Lin, P.L.1
Coleman, T.2
Carney, J.P.J.3
Lopresti, B.J.4
Tomko, J.5
Fillmore, D.6
Dartois, V.7
Scanga, C.8
Frye, L.J.9
Janssen, C.10
Klein, E.11
Barry, C.E.12
Flynn, J.L.13
-
25
-
-
84891853921
-
Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
-
P. L. Lin, C. B. Ford, M. T. Coleman, A. J. Myers, R. Gawande, T. Ioerger, J. Sacchettini, S. M. Fortune and J. L. Flynn, Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing, Nature medicine, 20 (2014), 75-79.
-
(2014)
Nature Medicine
, vol.20
, pp. 75-79
-
-
Lin, P.L.1
Ford, C.B.2
Coleman, M.T.3
Myers, A.J.4
Gawande, R.5
Ioerger, T.6
Sacchettini, J.7
Fortune, S.M.8
Flynn, J.L.9
-
26
-
-
70349427123
-
Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model
-
P. L. Lin, M. Rodgers, L. Smith, M. Bigbee, A. Myers, C. Bigbee, I. Chiosea, S. V. Capuano, C. Fuhrman, E. Klein and J. L. Flynn, Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model, Infection and immunity, 77 (2009), 4631-4642.
-
(2009)
Infection and Immunity
, vol.77
, pp. 4631-4642
-
-
Lin, P.L.1
Rodgers, M.2
Smith, L.3
Bigbee, M.4
Myers, A.5
Bigbee, C.6
Chiosea, I.7
Capuano, S.V.8
Fuhrman, C.9
Klein, E.10
Flynn, J.L.11
-
27
-
-
77951888203
-
Characterizing the dynamics of CD4+ T cell priming within a lymph node
-
J. J. Linderman, T. Riggs, M. Pande, M. Miller, S. Marino and D. E. Kirschner, Characterizing the dynamics of CD4+ T cell priming within a lymph node, Journal of immunology (Baltimore, Md.: 1950), 184 (2010), 2873-2885.
-
(2010)
Journal of Immunology (Baltimore, Md.: 1950)
, vol.184
, pp. 2873-2885
-
-
Linderman, J.J.1
Riggs, T.2
Pande, M.3
Miller, M.4
Marino, S.5
Kirschner, D.E.6
-
28
-
-
33846994373
-
Modelling the human immune response mechanisms to mycobacterium tuberculosis infection in the lungs
-
G. Magombedze, W. Garira and E. Mwenje, Modelling the human immune response mechanisms to mycobacterium tuberculosis infection in the lungs, Mathematical biosciences and engineering: MBE, 3 (2006), 661-682.
-
(2006)
Mathematical Biosciences and Engineering: MBE
, vol.3
, pp. 661-682
-
-
Magombedze, G.1
Garira, W.2
Mwenje, E.3
-
29
-
-
80053931194
-
A mathematical representation of the development of mycobacterium tuberculosis active, latent and dormant stages
-
G. Magombedze and N. Mulder, A mathematical representation of the development of Mycobacterium tuberculosis active, latent and dormant stages, Journal of theoretical biology, 292 (2012), 44-59.
-
(2012)
Journal of Theoretical Biology
, vol.292
, pp. 44-59
-
-
Magombedze, G.1
Mulder, N.2
-
30
-
-
79954611569
-
A hybrid multi-compartment model of granuloma formation and T cell priming in tuberculosis
-
S. Marino, M. El-Kebir and D. Kirschner, A hybrid multi-compartment model of granuloma formation and T cell priming in tuberculosis, Journal of theoretical biology, 280 (2011), 50-62.
-
(2011)
Journal of Theoretical Biology
, vol.280
, pp. 50-62
-
-
Marino, S.1
El-Kebir, M.2
Kirschner, D.3
-
31
-
-
45449094504
-
A methodology for performing global uncertainty and sensitivity analysis in systems biology
-
S. Marino, I. B. Hogue, C. J. Ray and D. E. Kirschner, A methodology for performing global uncertainty and sensitivity analysis in systems biology, Journal of theoretical biology, 254 (2008), 178-196.
-
(2008)
Journal of Theoretical Biology
, vol.254
, pp. 178-196
-
-
Marino, S.1
Hogue, I.B.2
Ray, C.J.3
Kirschner, D.E.4
-
32
-
-
1642407734
-
The human immune response to mycobacterium tuberculosis in lung and lymph node
-
S. Marino and D. E. Kirschner, The human immune response to Mycobacterium tuberculosis in lung and lymph node, Journal of theoretical biology, 227 (2004), 463-486.
-
(2004)
Journal of Theoretical Biology
, vol.227
, pp. 463-486
-
-
Marino, S.1
Kirschner, D.E.2
-
33
-
-
79960290056
-
A multifaceted approach to modeling the immune response in tuberculosis
-
S. Marino, J. J. Linderman and D. E. Kirschner, A multifaceted approach to modeling the immune response in tuberculosis, Wiley interdisciplinary reviews. Systems biology and medicine, 3 (2011), 479-489.
-
(2011)
Wiley Interdisciplinary Reviews. Systems Biology and Medicine
, vol.3
, pp. 479-489
-
-
Marino, S.1
Linderman, J.J.2
Kirschner, D.E.3
-
34
-
-
0036588794
-
A two-strain tuberculosis model with age of infection
-
F. A. Milner, M. Iannelli and Z. Feng, A Two-Strain Tuberculosis Model with Age of Infection, SIAM Journal on Applied Mathematics, 62 (2002), 1634-1656.
-
(2002)
SIAM Journal on Applied Mathematics
, vol.62
, pp. 1634-1656
-
-
Milner, F.A.1
Iannelli, M.2
Feng, Z.3
-
35
-
-
0036845362
-
Comparing epidemic tuberculosis in demographically distinct heterogeneous populations
-
B. M. Murphy, B. H. Singer, S. Anderson and D. Kirschner, Comparing epidemic tuberculosis in demographically distinct heterogeneous populations, Mathematical Biosciences, 180 (2002), 161-185.
-
(2002)
Mathematical Biosciences
, vol.180
, pp. 161-185
-
-
Murphy, B.M.1
Singer, B.H.2
Anderson, S.3
Kirschner, D.4
-
36
-
-
0038042464
-
On treatment of tuberculosis in heterogeneous populations
-
B. M. Murphy, B. H. Singer and D. Kirschner, On treatment of tuberculosis in heterogeneous populations, Journal of Theoretical Biology, 223 (2003), 391-404.
-
(2003)
Journal of Theoretical Biology
, vol.223
, pp. 391-404
-
-
Murphy, B.M.1
Singer, B.H.2
Kirschner, D.3
-
37
-
-
84875498895
-
The immune response in tuberculosis
-
A. O'Garra, P. S. Redford, F. W. McNab, C. I. Bloom, R. J. Wilkinson and M. P. R. Berry, The immune response in tuberculosis, Annual review of immunology, 31 (2013), 475-527.
-
(2013)
Annual Review of Immunology
, vol.31
, pp. 475-527
-
-
O'Garra, A.1
Redford, P.S.2
McNab, F.W.3
Bloom, C.I.4
Wilkinson, R.J.5
Berry, M.P.R.6
-
39
-
-
0025989790
-
Immunoarchitecture of regenerated splenic and lymph node transplants
-
R. Pabst, J. Westermann and H. J. Rothkotter, Immunoarchitecture of regenerated splenic and lymph node transplants, Int Rev Cytol, 128 (1991), 215-260.
-
(1991)
Int Rev Cytol
, vol.128
, pp. 215-260
-
-
Pabst, R.1
Westermann, J.2
Rothkotter, H.J.3
-
40
-
-
77955115175
-
Tissue-engineered lungs for in vivo implantation
-
T. H. Petersen, E. A. Calle, L. Zhao, E. J. Lee, L. Gui, M. B. Raredon, K. Gavrilov, T. Yi, Z. W. Zhuang, C. Breuer, E. Herzog and L. E. Niklason, Tissue-engineered lungs for in vivo implantation, Science, 329 (2010), 538-541.
-
(2010)
Science
, vol.329
, pp. 538-541
-
-
Petersen, T.H.1
Calle, E.A.2
Zhao, L.3
Lee, E.J.4
Gui, L.5
Raredon, M.B.6
Gavrilov, K.7
Yi, T.8
Zhuang, Z.W.9
Breuer, C.10
Herzog, E.11
Niklason, L.E.12
-
41
-
-
84860247190
-
Revisiting the role of the granuloma in tuberculosis
-
L. Ramakrishnan, Revisiting the role of the granuloma in tuberculosis, Nature reviews. Immunology, 12 (2012), 352-366.
-
(2012)
Nature Reviews. Immunology
, vol.12
, pp. 352-366
-
-
Ramakrishnan, L.1
-
42
-
-
20444419421
-
Genome-wide requirements for mycobacterium tuberculosis adaptation and survival in macrophages
-
J. Rengarajan, B. R. Bloom and E. J. Rubin, Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages, Proceedings of the National Academy of Sciences of the United States of America, 102 (2005), 8327-8332.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 8327-8332
-
-
Rengarajan, J.1
Bloom, B.R.2
Rubin, E.J.3
-
43
-
-
6344281115
-
Identifying control mechanisms of granuloma formation during M. Tuberculosis infection using an agent-based model
-
J. L. Segovia-Juarez, S. Ganguli and D. Kirschner, Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model, Journal of theoretical biology, 231 (2004), 357-376.
-
(2004)
Journal of Theoretical Biology
, vol.231
, pp. 357-376
-
-
Segovia-Juarez, J.L.1
Ganguli, S.2
Kirschner, D.3
-
44
-
-
6344221834
-
Influence of backward bifurcation on interpretation of r(0) in a model of epidemic tuberculosis with reinfection
-
B. H. Singer and D. E. Kirschner, Influence of backward bifurcation on interpretation of r(0) in a model of epidemic tuberculosis with reinfection, Mathematical biosciences and engineering: MBE, 1 (2004), 81-93.
-
(2004)
Mathematical Biosciences and Engineering: MBE
, vol.1
, pp. 81-93
-
-
Singer, B.H.1
Kirschner, D.E.2
-
45
-
-
84880664059
-
Differential virulence and disease progression following mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus)
-
L. E. Via, D. M. Weiner, D. Schimel, P. L. Lin, E. Dayao, S. L. Tankersley, Y. Cai, M. T. Coleman, J. Tomko, P. Paripati, M. Orandle, R. J. Kastenmayer, M. Tartakovsky, A. Rosenthal, D. Portevin, S. Y. Eum, S. Lahouar, S. Gagneux, D. B. Young, J. L. Flynn and C. E. Barry, Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus), Infection and immunity, 81 (2013), 2909-2919.
-
(2013)
Infection and Immunity
, vol.81
, pp. 2909-2919
-
-
Via, L.E.1
Weiner, D.M.2
Schimel, D.3
Lin, P.L.4
Dayao, E.5
Tankersley, S.L.6
Cai, Y.7
Coleman, M.T.8
Tomko, J.9
Paripati, P.10
Orandle, M.11
Kastenmayer, R.J.12
Tartakovsky, M.13
Rosenthal, A.14
Portevin, D.15
Eum, S.Y.16
Lahouar, S.17
Gagneux, S.18
Young, D.B.19
Flynn, J.L.20
Barry, C.E.21
more..
-
46
-
-
0035253576
-
A model to predict cell-mediated immune regulatory mechanisms during human infection with mycobacterium tuberculosis
-
J. E. Wigginton and D. Kirschner, A Model to Predict Cell-Mediated Immune Regulatory Mechanisms During Human Infection with Mycobacterium tuberculosis, The Journal of Immunology, 166 (2001), 1951-1967.
-
(2001)
The Journal of Immunology
, vol.166
, pp. 1951-1967
-
-
Wigginton, J.E.1
Kirschner, D.2
-
47
-
-
0037093992
-
Reevaluation of T cell receptor excision circles as a measure of human recent thymic emigrants
-
P. Ye and D. E. Kirschner, Reevaluation of T Cell Receptor Excision Circles as a Measure of Human Recent Thymic Emigrants, The Journal of Immunology, 168 (2002), 4968-4979.
-
(2002)
The Journal of Immunology
, vol.168
, pp. 4968-4979
-
-
Ye, P.1
Kirschner, D.E.2
-
48
-
-
45449110225
-
Systems biology of persistent infection: Tuberculosis as a case study
-
D. Young, J. Stark and D. Kirschner, Systems biology of persistent infection: Tuberculosis as a case study, Nature reviews. Microbiology, 6 (2008), 520-528.
-
(2008)
Nature Reviews. Microbiology
, vol.6
, pp. 520-528
-
-
Young, D.1
Stark, J.2
Kirschner, D.3
|