DNaseI protects against paraquat-induced acute lung injury and pulmonary fibrosis mediated by mitochondrial DNA

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Li, Guo ^a   Yuzhen, Li ^b   Yi, Chen ^b   Xiaoxiang, Chen ^a   Wei, Zhou ^b   Changqing, Zhu ^b   Shuang, Ye ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; COLLAGEN TYPE 1; DEOXYRIBONUCLEASE I; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOCHONDRIAL DNA; PARAQUAT; TRANSFORMING GROWTH FACTOR BETA1; PROTECTIVE AGENT; TUMOR NECROSIS FACTOR;

ACUTE LUNG INJURY; AMYOPATHIC DERMATOMYOSITIS-INTERSTITIAL LUNG DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERSTITIAL LUNG DISEASE; LUNG ALVEOLUS EPITHELIUM CELL; LUNG FIBROSIS; LUNG LAVAGE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED; EPITHELIUM CELL; GENETICS; METABOLISM; MITOCHONDRION; TUMOR CELL LINE;

ACUTE LUNG INJURY; ANIMALS; BLEOMYCIN; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CELL LINE, TUMOR; COLLAGEN TYPE I; DEOXYRIBONUCLEASE I; DNA, MITOCHONDRIAL; EPITHELIAL CELLS; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; PARAQUAT; PROTECTIVE AGENTS; PULMONARY FIBROSIS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84924122463     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/386952     Document Type: Article

References (44)

1. M. Cepkova and M. A. Matthay, "Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome," Journal of Intensive Care Medicine, vol. 21, no. 3, pp. 119-143, 2006.
2. R. E. Murray and J.E. Gibson, "Acomparative study of paraquat intoxication in rats, guinea pigs and monkeys," Experimental and Molecular Pathology, vol. 17, no. 3, pp. 317-325, 1972.
3. R. B. Bruyndonckx, A. I. Meulemans, M. B. Sabbe, A. A. Kumar, and H. H. Delooz, "Fatal intentional poisoning cases admitted to the University Hospitals of Leuven, Belgium from 1993 to 1996," European Journal of Emergency Medicine, vol. 9, no. 3, pp. 238-243, 2002.
4. C.-M. Chenand A. C. Lua, "Lung toxicityofparaquat inthe rat," Journal of Toxicology and Environmental Health A, vol. 60, no. 7, pp. 477-487, 2000.
5. R. J. Dinis-Oliveira, J. A. Duarte, A. Sánchez-Navarro, F. Remião, M. L. Bastos, and F. Carvalho, "Paraquat poisonings: mechanisms of lung toxicity, clinical features, and treatment," Critical Reviews in Toxicology, vol. 38, no. 1, pp. 13-71, 2008.
6. M. Ghazi-Khansari, G. Nasiri, and M. Honarjoo, "Decreasing the oxidant stress from paraquat in isolated perfused rat lung using captopril and niacin," Archives of Toxicology, vol. 79, no. 6, pp. 341-345, 2005.
7. P. Slade, "The fate of paraquat applied to plants," Weed Research, vol. 6, no. 2, pp. 158-167, 1966.
8. J. C. Gage, "The action of paraquat and diquat on the respiration of liver cell fractions," Biochemical Journal, vol. 109, no. 5, pp. 757-761, 1968.
9. K. I. Hirai, H. Witschi, and M. G. Cote, "Mitochondrial injury of pulmonary alveolar epithelial cells in acute paraquat intoxication," Experimental and Molecular Pathology, vol. 43, no. 2, pp. 242-252, 1985.
10. G. Y. Wang, K. Hirai, and H. Shimada, "Mitochondrial breakage induced by the herbicide paraquat in cultured human lung cells," Journal of Electron Microscopy (Tokyo), vol. 41, no. 3, pp. 181-184, 1992.
11. E. D. Carson, "Fatal paraquat poisoning in Northern Ireland," Journal of the Forensic Science Society, vol. 12, no. 3, pp. 437-443, 1972.
12. P. Costantini, V. Petronilli, R. Colonna, and P. Bernardi, "On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide," Toxicology, vol. 99, no. 1-2, pp. 77-88, 1995.
13. S. DiMauro and E. A. Schon, "Mitochondrial respiratory-chain diseases," The New England Journal of Medicine, vol. 348, no. 26, pp. 2656-2668, 2003.
14. H. Hemmi, O. Takeuchi, T. Kawai et al., "A Toll-like receptor recognizes bacterial DNA," Nature, vol. 408, no. 6813, pp. 740-745, 2000.
15. S. Bauer, C. J. Kirschning, H. Häcker et al., "Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition," Proceedings of the National Academy of Sciences of the United States of America, vol. 98, no. 16, pp. 9237-9242, 2001.
16. Q. Zhang, M. Raoof, Y. Chen et al., "Circulating mitochondrial DAMPs cause inflammatory responses to injury," Nature, vol. 464, no. 7285, pp. 104-107, 2010.
17. A. A. Manfredi and P. Rovere-Querini, "The mitochondrion-a Trojan horse that kicks off inflammation?" The New England Journal of Medicine, vol. 362, no. 22, pp. 2052-2134, 2010.
18. P. Mitsopoulos and Z. E. Suntres, "Cytotoxicity and gene array analysis of alveolar epithelial A549 cells exposed to paraquat," Chemico-Biological Interactions, vol. 188, no. 3, pp. 427-436, 2010.
19. Z. Fekete, C. J. Hauser, J. M. Adams et al., "Injury-enhanced calcium mobilization in circulating rat neutrophils models human PMN responses," Shock, vol. 16, no. 1, pp. 15-20, 2001.
20. S.M. Camp, R. Bittman, E. T. Chiang et al., "Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro," Journal of Pharmacology and Experimental Therapeutics, vol. 331, no. 1, pp. 54-64, 2009.
21. N. Hattori, J. L. Degen, T. H. Sisson et al., "Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice," Journal of Clinical Investigation, vol. 106, no. 11, pp. 1341-1350, 2000.
22. T. Ashcroft, J. M. Simpson, and V. Timbrell, "Simple method of estimating severity of pulmonary fibrosis on a numerical scale," Journal of Clinical Pathology, vol. 41, no. 4, pp. 467-470, 1988.
23. + monocytes into fibrocytes," Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 42, pp. 17892-17897, 2009.
24. J. S. Bus and J. E. Gibson, "Paraquat:model for oxidant-initiated toxicity," Environmental Health Perspectives, vol. 55, pp. 37-46, 1984.
25. V. Mollace, M. Iannone, C. Muscoli et al., "The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic," Neuroscience Letters, vol. 335, no. 3, pp. 163-166, 2003.
26. A. Mohammadi-Bardbori and M. Ghazi-Khansari, "Alternative electron acceptors: proposed mechanism of paraquat mitochondrial toxicity," Environmental Toxicology and Pharmacology, vol. 26, no. 1, pp. 1-5, 2008.
27. P. R. Castello, D. A. Drechsel, and M. Patel, "Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain," The Journal of Biological Chemistry, vol. 282, no. 19, pp. 14186-14193, 2007.
28. H. van Remmen and A. Richardson, "Oxidative damage to mitochondria and aging," Experimental Gerontology, vol. 36, no. 7, pp. 957-968, 2001.
29. K. Nakahira, J. A. Haspel, V. A. K. Rathinam et al., "Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome," Nature Immunology, vol. 12, no. 3, pp. 222-230, 2011.
30. Y.-W. Chen, Y.-T. Yang, D.-Z. Hung, C.-C. Su, and K.-L. Chen, "Paraquat induces lung alveolar epithelial cell apoptosis via Nrf-2-regulated mitochondrial dysfunction and ER stress," Archives of Toxicology, vol. 86, no. 10, pp. 1547-1558, 2012.
31. B. A. Davidson, R. R. Vethanayagam, M. J. Grimm et al., "NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury," The Journal of Immunology, vol. 190, no. 4, pp. 1714-1724, 2013.
32. J. Athale, A. Ulrich, N. Chou MacGarvey et al., "Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice," Free Radical Biology and Medicine, vol. 53, no. 8, pp. 1584-1594, 2012.
33. J. Qian, Y. Ye, L. Lv, C. Zhu, and S. Ye, "FTY720 attenuates paraquat-induced lung injury in mice," International Immunopharmacology, vol. 21, no. 2, pp. 426-431, 2014.
34. T. Izumo, M. Kondo, and A. Nagai, "Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis," European Respiratory Journal, vol. 34, no. 6, pp. 1444-1451, 2009.
35. H. J. Fuchs, D. S. Borowitz, D. H. Christiansen et al., "Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis," The New England Journal of Medicine, vol. 331, no. 10, pp. 637-642, 1994.
36. M. Napirei, H. Karsunky, B. Zevnik, H. Stephan, H. G. Mannherz, and T. Möröy, "Features of systemic lupus erythematosus in Dnase1-deficient mice," Nature Genetics, vol. 25, no. 2, pp. 177-181, 2000.
37. K. Yasutomo, T. Horiuchi, S. Kagami et al., "Mutation of DNASE1 in people with systemic lupus erythematosus," Nature Genetics, vol. 28, no. 4, pp. 313-314, 2001.
38. J.C. Davis Jr., S. Manzi, C. Yarboro et al., "Recombinant human Dnase I (rhDNase) in patients with lupus nephritis," Lupus, vol. 8, no. 1, pp. 68-76, 1999.
39. A. Caudrillier, K. Kessenbrock, B. M. Gilliss et al., "Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury," Journal of Clinical Investigation, vol. 122, no. 7, pp. 2661-2671, 2012.
40. S. Ye, X. X. Chen, X. Y. Lu et al., "Adult clinically amyopathic dermatomyositiswith rapid progressive interstitial lung disease: a retrospective cohort study," Clinical Rheumatology, vol. 26, no. 10, pp. 1647-1654, 2007.
41. M. Hashizume, M. Mouner, J. M. Chouteau et al., "Mitochondrial-targeted DNA repair enzyme 8-oxoguanine DNA glycosylase 1 protects against ventilator-induced lung injury in intact mice," The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 304, no. 4, pp. L287-L297, 2013.
42. S. A. Gebb, A. Decoux, A. Waggoner, G. L. Wilson, and M. N. Gillespie, "Mitochondrial DNA damage mediates hyperoxic dysmorphogenesis in rat fetal lung explants," Neonatology, vol. 103, no. 2, pp. 91-97, 2013.
43. J. M. Chouteau, B. Obiako, O. M. Gorodnya et al., "Mitochondrial DNA integritymay be a determinant of endothelial barrier properties in oxidant-challenged rat lungs," The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 301, no. 6, pp. L892-L898, 2011.
44. M. V. Ruchko, O. M. Gorodnya, A. Zuleta, V. M. Pastukh, and M. N. Gillespie, "The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells," Free Radical Biology and Medicine, vol. 50, no. 9, pp. 1107-1113, 2011.