Attenuation of acute stroke injury in rat brain by minocycline promotes blood-brain barrier remodeling and alternative microglia/macrophage activation during recovery

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Yang, Yirong ^b   Salayandia, Victor M ^a   Thompson, Jeffrey F ^a   Yang, Lisa Y ^a   Estrada, Eduardo Y ^a   Yang, Yi ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

Inflammatory phenotypes; Microglia macrophage; Minocycline; MRI; Neurovascular remodeling; Stroke recovery; Tight junction proteins

Indexed keywords

CYTOKINE; GELATINASE A; INTERLEUKIN 10; INTERLEUKIN 1BETA; MINOCYCLINE; STROMELYSIN; TIGHT JUNCTION PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; YM1 PROTEIN; GELATINASE B; RECA PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL SPIN LABELING; ARTICLE; BIOCHEMISTRY; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN PERFUSION; BRAIN TISSUE; CEREBROVASCULAR ACCIDENT; CONTRAST ENHANCEMENT; CONTROLLED STUDY; HEMISPHERE; IMMUNOHISTOCHEMISTRY; MACROPHAGE ACTIVATION; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; RAT; SINGLE DRUG DOSE; SPIN LABELING; SPONTANEOUSLY HYPERTENSIVE RAT; TISSUE INJURY; WESTERN BLOTTING; ANIMAL; BRAIN CIRCULATION; CONVALESCENCE; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; MACROPHAGE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REPERFUSION; TIME FACTOR;

ANIMALS; BLOOD-BRAIN BARRIER; CEREBROVASCULAR CIRCULATION; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICROGLIA; MINOCYCLINE; RATS; RATS, INBRED SHR; REC A RECOMBINASES; RECOVERY OF FUNCTION; REPERFUSION; TIME FACTORS;

EID: 84924096827     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0245-4     Document Type: Article

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